CAR-T CELL THERAPY IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA by Ugo Testa, Simona Sica, Elvira Pelosi, Germana Castelli, Giuseppe Leone

“…CD19 CAR-T cells induce a high rate (80-90%) of complete remissions in both pediatric and adult R/R B-ALL patients. However, despite this impressive rate of responses, about half of responding patients relapse within 1-2 years after CAR-T cell therapy. …”
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Evaluating ChatGPT-4's performance on oral and maxillofacial queries: Chain of Thought and standard method by Kaiyuan Ji, Zhihan Wu, Jing Han, Guangtao Zhai, Guangtao Zhai, Jiannan Liu

“…These questions encompass 12 areas of oral and maxillofacial surgery, including Prosthodontics, Pediatric Dentistry, Maxillofacial Tumors and Salivary Gland Diseases, and maxillofacial Infections.ResultsUsing CoT approach, ChatGPT-4 exhibited marked enhancements in accuracy, structure, completeness, professionalism, and overall impression for open-ended questions, revealing statistically significant differences compared to its performance on general oral and maxillofacial inquiries. …”
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Prevalence of vitamin D deficiency in children with cerebral palsy and autism spectrum disorder: a comparative pilot study by Ruzha Pancheva, Albena Toneva, Yana Bocheva, Miglena Georgieva, Krassimira Koleva, Ivan Yankov

“…The findings emphasize the role of biological and sociocultural factors in the prevalence of VDD, contributing valuable insights into pediatric health in moderate-climate regions.…”
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Fingertip traumatic amputations in children. Treatment with semiocclusive foil dressings-preliminary results by Dimitar Trizlov, Dimitar Raykov, Stoyan Ivanov, Ivan Trizlov

“…Treatment with semi-occlusive dressings is a minimally invasive method, particularly suitable for the pediatric age group. Conclusion: Treatment of fingertip amputations with semi-occlusive foil dressings offers several advantages in childhood. …”
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Case report: Clinical characteristics and Genetical analysis of HSD11B2 in three Chinese children with apparent mineralocorticoid excess: a case series by Yuan Ding, Yuan Ding, Ming Cheng, Ming Cheng, Bingyan Cao, Bingyan Cao, Min Liu, Min Liu, Xuyun Hu, Xuyun Hu, Di Wu, Di Wu, Di Wu

“…Treatment with oral spironolactone and potassium chloride resulted in the normalization of both blood pressure and serum potassium levels in all patients.ConclusionThis study presents the diagnostic and treatment experiences of three Chinese pediatric patients with AME type I. Through our analysis, four novel variants of the HSD11B2 gene were identified, thereby enhancing the genotype-phenotype spectrum associated with AME. …”
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Impact of laparoscopic surgeries on optic nerve sheath diameter (ONSD) in children by Mohsina Yasmeen, Sumaiya Sabreen, Akshay Bettanayaka, Saraswathi Nagappa

“…Methods: In this prospective observational study, 23 pediatric patients aged between 5 and 16 years, undergoing elective laparoscopic procedures under general anesthesia, were included. …”
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Combining interictal intracranial EEG and fMRI to compute a dynamic resting-state index for surgical outcome validation by Varina L. Boerwinkle, Kristin M. Gunnarsdottir, Bethany L. Sussman, Sarah N. Wyckoff, Emilio G. Cediel, Belfin Robinson, William R. Reuther, Aryan Kodali, Sridevi V. Sarma

“…The SSI scores were evaluated in 17 pediatric drug-resistant epilepsy (DRE) patients (ages 3–15 years) by comparing outcomes classified as successful (Engel I or II) versus unsuccessful (Engel III or IV) at 1 year post-surgery.ResultsOf 30 reviewed patients, 17 met the inclusion criteria. …”
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Seizures elicited by transcorneal 6 Hz stimulation in developing rats. by Pavel Mareš, Cameron S Metcalf, Jiří Baloun, Hana Kubová

“…The data extend the use of the rat 6 Hz model to immature animals and may be useful as a model of pediatric temporal lobe seizures.…”
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UPDATE ON CYTOMEGALOVIRUS INFECTION MANAGEMENT IN ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANT RECIPIENTS by José Luis Piñana, Estela Giménez, Lourdes Vázquez, María Ángeles Marcos, Manuel Guerreiro, Rafael Duarte, Ariadna Pérez, Carlos de Miguel, Ildefonso Espigado, Marta González-Vicent, María Suarez-Lledó, Irene García-Cadenas, Rodrigo Martino, Angel Cedillo, Monserrat Rovira, Rafael de la Cámara, David Navarro, Carlos Solano

“…Further research is warranted to validate these recommendations and address ongoing challenges in CMV management with emerging antiviral combinations, particularly in pediatric populations. …”
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Post-traumatic pituitary stalk transection syndrome (PSTS) expeditiously manifested after a fall from a height combined with acute traumatic spinal cord injury: a rare case report... by Yohei Ishiki, Atsuko Tamaki, Ken-ichiro Honma, Ken Yonaha, Takamitsu Yabiku, Taiki Teruya, Moriyuki Uehara, Yoshiro Nakayama, Rei Chinen, Tsugumi Uema, Sawako Nakachi, Shiki Okamoto, Hiroaki Masuzaki

“…In typical PSIS, anterior pituitary hormone deficiencies are restricted to growth hormone (GH) and gonadotropin during the pediatric age, gradually and generally progressing to panhypopituitarism in most cases. …”
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Urethral Prolapse Case Report: Surgical and Social Considerations in Senegal by Mohamed Jalloh, Jennifer Heibig, Oumar Gaye, William Ghaul, Gabrielle Yankelevich, Medina Ndoye, Mouhamadou Moustapha Mbodji, Ayun Cassell, Lamine Niang, Serigne Magueye Gueye

“…This case report on pediatric urethral prolapse showcases the different presentations and modalities of treatment, as the literature does not show that a specific treatment is always undertaken. …”
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Anxiety and depression in childhood rheumatologic conditions: A topical review by Mallet R Reid, Jacqueline Fabricius, Ashley Danguecan, Kaveh Ardalan, Andrea Knight, Natoshia R Cunningham

“…An improved understanding of mental health functioning in pediatric patients presenting for rheumatologic care may inform the development and testing of tailored and effective treatments.…”
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Risk factors for type 2 diabetes mellitus in adolescentes by Wendy Valdés Gómez, Arianna Almirall Sánchez, Miguel Ángel Gutiérrez Pérez

“…<strong>Foundation:</strong> The increasing prevalence of diabetes mellitus type 2 (DM2) from the pediatric ages, has made its morbidity and mortality a major public health problem. …”
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Text messaging to improve connection between adolescents and their health care providers by Claire R Galvin, Astrid M De Souza, James E Potts, Penny L Sneddon, Shubhayan Sanatani, Kathryn R Armstrong

“…Methods Participants (age 12–18) with access to a personal mobile phone were recruited from a pediatric dysautonomia clinic. A weekly automated text message asking “How are you?” …”
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Dermoscopic Features of Diaper Dermatoses in Children: A Descriptive Pilot Study by Neha Dhawan, Mohammed Shahana, Mudiam Nagaswetha, Rama M. Cheedirala, Sudharani Chintagunta, G. Narasimha Rao Netha

“…Conclusion: This study highlights the dermoscopic features of diaper dermatoses and demonstrates the potential of dermoscopy to enhance diagnostic accuracy and optimize patient care without invasive investigations, underscoring its unique role in pediatric dermatology.…”
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Making respiratory care safe for neonatal and paediatric intensive care unit staff: Mitigation strategies and use of filters by Bradley G Carter, Edward Harcourt, Alexandra Harris, Michael Zampetti, Trevor Duke, David Tingay

“…# Background Many medical devices in pediatric and newborn intensive care units can potentially expose healthcare workers (HCWs) and others to transmission of respiratory and other viruses and bacteria. …”
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Effect of Tronclass combined with team-based learning on nursing students’ self-directed learning and academic performance: a pretest-posttest study by Longyi Hu, Siqi Li, Leshan Zhou

“…Methods This study used Tronclass to carry out team-based learning in the teaching process of pediatric nursing courses. It compared the self-directed learning ability nursing students before and after courses, and juxtaposed their academic performance with those of their counterparts who graduated in previous years. …”
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The Impact of Preoperative Fasting Duration on Blood Glucose and Hemodynamics in Children by Pouran Hajian, Minoo Shabani, Elham Khanlarzadeh, Mahshid Nikooseresht

“…Prolonged preoperative fasting is one of the concerns of pediatricians and anesthesiologists in pediatric surgery. The aim of this study was to assess the impact of preoperative fasting duration on blood glucose and hemodynamics in children. …”
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Cardiovascular Characterization of Children and Adolescents with Sickle Cell Anemia by Nancy González Vales, Ximena Laura Graña, Lucía Díaz Morejón, Tamara Sánchez Estrada, Belkis Rodríguez Jorge, Ifraín Machín Caride

“…<br /><strong>Methods:</strong> a descriptive and cross-sectional study was conducted in the hematology and cardiology consultations of the Paquito González Cueto de Cienfuegos University Pediatric Hospital from July 1, 2011 to July 31, 2012. …”
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Evaluation of the Relationship Between Histopathological Tissue Diagnosis and Endometrial Thickness in Cases with Postmenopausal Bleeding by Mehmet Şükrü Budak, Mehmet Baki Şentürk, Sedat Akgöl, Mehmet Obut, Ali Emre Tahaoğlu, Cihan Toğrul, Ayhan Yıldırım

“…STUDY DESIGN: The results of 235 cases, where endometrial sampling has been made due to postmenopausal bleeding at the Diyarbakır Maternity and Pediatric Hospital between January 2013 and December 2013, have been evaluated retrospectively. …”
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