Understanding variation in management of early-onset neonatal sepsis in India: a vignette-based survey by Christina M Schumacher, Samuel McAleese, Tushar B Parikh, Basma Ouddi, Julia Johnson

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Normothermic Ex Vivo Heart Perfusion with Mesenchymal Stem Cell-Derived Conditioned Medium Improves Myocardial Tissue Protection in Rat Donation after Circulatory Death Hearts by Zifeng Zeng, Liwei Xu, Yu Xu, Yongsheng Ruan, Deshen Liu, Jiale Li, Chuanjie Niu, Shaoyi Zheng, Pengyu Zhou, Zezhou Xiao

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Long-term Results in Children with Henoch-Schönlein Nephritis by Caner ASLAN, Nilufer GOKNAR, Emre KELESOGLU, Diana UCKARDES, Cengiz CANDAN

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Preclinical use of a clinically-relevant scAAV9/SUMF1 vector for the treatment of multiple sulfatase deficiency by Maximiliano Presa, Rachel M. Bailey, Somdatta Ray, Lauren Bailey, Saurabh Tata, Tara Murphy, Pierre-Alexandre Piec, Harold Combs, Steven J. Gray, Cathleen Lutz

“…Abstract Background Multiple Sulfatase Deficiency (MSD) is a rare inherited lysosomal storage disorder characterized by loss of function mutations in the SUMF1 gene that manifests as a severe pediatric neurological disease. There are no available targeted therapies for MSD. …”
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Chronic Kidney Disease Stage Is a Modulator on the Association between High-Sensitivity C-Reactive Protein and Coronary Vasospastic Angina by Heng-Jung Hsu, Chiung-Hui Yen, Kuang-Hung Hsu, I-Wen Wu, Chin-Chan Lee, Chiao-Yin Sun, Chia-Chi Chou, Chun-Yu Chen, Shih-Ying Yang, Chi-Jen Tsai, Mai-Szu Wu, Ming-Jui Hung

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Consequences of early life exposure to the 1983–1985 Ethiopian Great Famine on cognitive function in adults: a historical cohort study by Mubarek Abera, Getachew Arage, Tefera Belachew, Fedilu Abdulhay, Misra Abdulahi, Kalkidan Hassen Abate

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Prenatal Counseling and Diagnosis of COX20 Gene-Related Mitochondrial Complex IV Deficiency: A Case Report and Literature Review by Su J, Zeng L, Chen H, Tong J, Chen Y, Huang L, Deng L, Huang Y

“…We report a case of COX20 gene associated mitochondrial complex IV deficiency in a child, and describe the prenatal counseling and prenatal diagnosis of the mother in subsequent pregnancies to provide reference for prenatal counseling and prenatal diagnosis of this disease.Case Presentation: In this study, we presented a case of a pediatric patient who displayed symptoms such as gait instability, ataxia, cognitive impairment, dysarthria, muscle weakness, and absent reflexes. …”
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Hypoxia inducible factor-dependent upregulation of Agrp in glomus type I cells of the carotid body by Luis Leon-Mercado, Ivan Menendez-Montes, Jonathan Tao, Bandy Chen, David P. Olson, C. Mackaaij, C.G.J. Cleypool, Laurent Gautron

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Learned phenotypes emerge during social stress modifying hippocampal orexin receptor gene expression by Jazmine D. W. Yaeger, Justin K. Achua, Clarissa D. Booth, Delan Khalid, Megan M. John, Leighton J. Ledesma, Trent L. Greschke, Ashley M. Potter, Chase B. Howe, Kevin T. Krupp, Justin P. Smith, Patrick J. Ronan, Cliff H. Summers

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Decreased Taurine and Creatine in the Thalamus May Relate to Behavioral Impairments in Ethanol-Fed Mice: A Pilot Study of Proton Magnetic Resonance Spectroscopy by Su Xu PhD, Wenjun Zhu MS, Yamin Wan MD, PhD, JiaBei Wang PhD, Xi Chen PhD, Liya Pi PhD, Mary Kay Lobo PhD, Bin Ren PhD, Zhekang Ying PhD, Michael Morris MD, Qi Cao MD, PhD

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Point-of-care lung ultrasound in detecting pneumonia: A systematic review by Iqra Abid, Nadia Qureshi, Nicola Lategan, Simon Williams, Sidra Shahid

“…This review aimed to investigate the benefits of point-of-care LUS for the early diagnosis of pneumonia compared to traditional chest X-rays (CXR) in a subgroup analysis including pediatric, adult, and geriatric populations. # Material and Methods This systematic review examined systematic reviews, meta-analyses, and original research from 2017 to 2021, comparing point-of-care LUS and CXR in diagnosing pneumonia among adults, pediatrics and geriatrics. …”
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Disorder of intracellular cobalamin metabolism: Importance of rapid diagnostic illustrated by a case report of early-onset methylmalonic aciduria and homocystinuria, cobalamin C ty... by Etienne Mondesert, Bastien Baud, Agathe Roubertie, Jean-François Benoist, Pierre-Edouard Grillet, Jean-Paul Cristol, Marie Céline Francois-Heude, Manuel Schiff, Stéphanie Badiou

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Routine antibiotics for infants less than 6 months of age with growth failure/faltering: a systematic review by Jai K Das, Zulfiqar Ahmed Bhutta, Abigail Smith, Aamer Imdad, Olivia Tsistinas, Emily Tanner-Smith, Melissa François, Fanny F Chen, Momal Sana

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CXCL8 modulates M0 macrophage proliferation and polarization to influence tumor progression in cervical cancer by Xiyan Zhao, Li Yang, Jigang Pan, Zhirui Zeng, Tuo Zhang, Yushi Yang, Jingjing Zhang, Tengxiang Chen, Ziwen Xiao, Wei Pan

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Association of Xmn I Polymorphism and Hemoglobin E Haplotypes on Postnatal Gamma Globin Gene Expression in Homozygous Hemoglobin E by Supachai Ekwattanakit, Yuwarat Monteerarat, Suchada Riolueang, Kalaya Tachavanich, Vip Viprakasit

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Case studies in adaptation: centring equity in global health education during the COVID-19 pandemic and beyond by Anna Pancheshnikov, C Nicholas Cuneo, Wilfredo R Matias, Rebeca Cázares-Adame, Abner Gamaliel Santos López, Ryan M Paxton, Chi Chiung Grace Chen

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Impact of Long COVID on Lung Function in Children by Zeynep Reyhan ONAY, Sinem CAN OKSAY, Deniz MAVI TORTOP, Gulay BILGIN, Yetkin AYHAN, Ferit DURANKUS, Saniye GIRIT

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Perspectives on adapting a mobile application for pain self-management in neurofibromatosis type 1: results of online focus group discussions with individuals living with neurofibr... by Chitra Lalloo, Lauretta E Grau, Kaitlyn Larkin, Jennifer N Stinson, William T Zempsky, Samuel A Ball, Frank D Buono

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Reliability, Objectivity, Validity and Reference Levels of the Austrian Balance Check (ABC)—A Novel Balance Field Test for Children, Adolescents and Young Adults to Assess Static B... by Gerald Jarnig, Reinhold Kerbl, Mireille N. M. van Poppel

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Mitochondrial trifunctional protein deficiency caused by a deep intronic deletion leading to aberrant splicing by Thomas Cassini, Sarah Silverstein, Molly Behan, Cynthia J. Tifft, May Christine Malicdan, David R. Adams, Undiagnosed Diseases Network, Sun‐Young Ahn, Debra S. Regier

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