Conversion from clinically isolated syndrome to multiple sclerosis: what paraclinical tests findings are the most characteristic? by M. Malciūtė, I. Čelpačenko, R. Stankevičiūtė, R. Balnytė

“…The results indicate that pathological CSF findings (positive OCBs, elevated IgG levels) and prolonged BAEP latency are characteristic in patients with CIS who later progress to MS. …”
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Relationship between CCL25/CCR9 Levels in Follicular Fluid and High Ovarian Response in Patients with Polycystic Ovary Syndrome by Yongxin Hao, Qianqian Yin, Fangfang Hu, Xiaoyan Liu, Yaru Yang, Fang Sun, Xiaonan Yan

“…The current study aimed at investigating whether CCL25/CCR9 plays a role in the pathological process of high ovarian response (HOR) during COS procedures. …”
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Simulated low-dose dark-field radiography for detection of COVID-19 pneumonia. by Rafael C Schick, Henriette Bast, Manuela Frank, Theresa Urban, Thomas Koehler, Florian T Gassert, Andreas P Sauter, Bernhard Renger, Alexander A Fingerle, Alexandra Karrer, Marcus R Makowski, Daniela Pfeiffer, Franz Pfeiffer

“…Patients were included if they had a CO-RADS (COVID-19 Reporting and Data System) score ≥ 4 (COVID-19 group) or if they had no pathologic lung changes (controls). A total of 89 participants with a median age of 60 years (interquartile range 48 to 68 yrs.) were included in this study. …”
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The infiltration risk prediction models by logistic regression for ground-glass pulmonary nodules: a systematic review and meta-analysis by Mengqian Li, Mengqian Li, Xiaomei Zhang, Yuxin Lai, Yunlong Sun, Tianshu Yang, Xinlei Tan

“…The modeling group was patients with a pathological diagnosis of ground-glass pulmonary nodules. …”
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Meta-analysis of the accuracy for RASSF1A methylation in bronchial aspirates for the diagnosis of lung cancer. by Xu-Ping Chen, Shi-Xu He, Meng-You Chen, Fu-Bin Chen, Peng Wu, Ping Shi, Shi-Cai Zhao, Ling-Yan Zhao, Xiao-Min Xiong, Jia Zeng

“…The pooled results for the diagnosis of lung cancer were as follows, when compared to the pathological diagnosis: sensitivity of 0.47 (95% CI: 0.45-0.50), specificity of 0.96 (95% CI: 0.95-0.97), positive LR of 12.18 (95% CI: 8.96-16.55), negative LR of 0.56 (95% CI: 0.52-0.61), DOR of 24.05 (95% CI: 17.29-33.47), and AUC of 0.78 (Q index = 0.72), respectively. …”
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Construction and validation of a prognostic model for NK/T-cell lymphoma based on random survival forest algorithm by HUANG Zhen, HUANG Zhen, WU Yazhou

“…Methods‍　‍Demographic and clinical pathological data of NKTL patients were collected from the SEER database during 2000 and 2020. …”
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Multivariate description of gait changes in a mouse model of peripheral nerve injury and trauma. by Bilal A Naved, Shuling Han, Kyle M Koss, Mary J Kando, Jiao-Jing Wang, Craig Weiss, Maya G Passman, Jason A Wertheim, Yuan Luo, Zheng J Zhang

“…This study contributes a comprehensive, multivariate characterization pipeline for application in the study of any pathologies in which gait is a quantitative translational outcome metric.…”
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Clinical and endoscopical and morphofunctional scores in evaluation of development of gastroesophageal reflux disease in various age groups by M. A. Osadchuk, A. M. Zolotovitskaya, N. V. Kireyeva, S. N. Nikolenko, I. M. Kvetnoy

“…However, disorder of neurohumoral regulation and pathological acid production, exhausting compensatory potential of the body, play the leading role. …”
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Automated Quantification of Retinopathy of Prematurity Stage via Ultrawidefield OCT by Spencer S. Burt, BA, Aaron S. Coyner, PhD, Elizabeth V. Roti, BS, Yakub Bayhaqi, PhD, John Jackson, MD, Mani K. Woodward, MS, Shuibin Ni, PhD, Susan R. Ostmo, MS, Guangru Liang, BS, Yali Jia, PhD, David Huang, MD, Michael F. Chiang, MD, Benjamin K. Young, MD, Yifan Jian, PhD, John Peter Campbell, MD

“…Purpose: Retinopathy of prematurity (ROP) stage is defined by the visual appearance of the vascular-avascular border, which reflects a spectrum of pathologic neurovascular tissue (NVT). Previous work demonstrated that the thickness of the ridge lesion, measured using OCT, corresponds to higher clinical diagnosis of stage. …”
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Nonspecific response of Lake Baikal phytoplankton to anthropogenic impact by A. A. Nikonova, S. S. Vorobyeva

“…The presence of these substances in a water ecosystem can result in exhausting of phytoplankton cell resources, homeostasis imbalance, stress, pathological changes, and rearrangements in phytoplankton assemblage.…”
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Structure of mycoses of the skin and its appendices in HIV-infected patients by V.D. Moskaliuk, I.I. Kravchuk, Yu.O. Randiuk, I.V. Balaniuk

“…Mycological examination included micro­scopy of pathological material and cultural diagnosis. Analysing the structure of the disease it was found that skin mycoses and its appendages were detected in 334 (41,7%) HIV-infected patients. …”
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Breeding results for Echinacea purpurea (L.) Moench in Moscow Province by I. N. Korotkikh, E. Yu. Babaeva, A. E. Burova

“…Preparations from crude herbal materials of E. purpurea have a widerange effect against pathologies of the immune system, infectious and inflammatory diseases of the respiratory tract, genitourinary system and musculoskeletal system. …”
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Disruption of tumor-intrinsic PGAM5 increases anti-PD-1 efficacy through the CCL2 signaling pathway by Yan Li, Hong Wang, Xiaoyang Li, Yuan He, Huiquan Liu, Dong Han, Ting Mei, Yixuan Li, Zilong Xu, Xiaoying Wei, Jianguo Wang, Peijie Zhou, Yuwen Wang, Ziye Li, Junhao Ning, Anlin Wang, Jingjing Cheng, Dong Qian

“…High tumor-intrinsic PGAM5 expression promoting M2 TAMs infiltration correlated with poor clinical-pathological characteristics and prognosis in patients with HCC. …”
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Transplantation of mitochondria from human malignant tumor cells as a method of tumor growth formation in the lungs of laboratory animals by O. I. Kit, E. M. Frantsiyants, A. I. Shikhlyarova, I. V. Neskubina

“…Multinucleated cells, as well as pathological mitoses with clearly marked division figures, which testified to their proliferative activity, were encountered with a rather high frequency.Conclusions. …”
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Antimicrobial Resistance Genes in Clinical <i>Escherichia coli</i> Strains from Livestock and Poultry in Shandong Province, China During 2015–2020 by Miaoli Wang, Shaopeng Wu, Yao Wang, Feng Chen, Zhangqi Shen, Zouran Lan

“…<b>Objective:</b> The aim of this study was to explore the genetic characteristics, co-occurrence, and correlations between ARGs of <i>E. coli</i> isolated from the pathological tissues of livestock and poultry in Shandong Province, East China during 2015–2020. …”
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Machine learning for predicting neoadjuvant chemotherapy effectiveness using ultrasound radiomics features and routine clinical data of patients with breast cancer by Pu Zhou, Pu Zhou, Hongyan Qian, Pengfei Zhu, Jiangyuan Ben, Jiangyuan Ben, Guifang Chen, Qiuyi Chen, Lingli Chen, Jia Chen, Ying He, Ying He

“…BackgroundThis study explores the clinical value of a machine learning (ML) model based on ultrasound radiomics features of primary foci, combined with clinicopathologic factors to predict the pathological complete response (pCR) of neoadjuvant chemotherapy (NAC) for patients with breast cancer (BC).MethodWe retrospectively analyzed ultrasound images and clinical information from 231 participants with BC who received NAC. …”
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Estudio genético en adultos con glomeruloesclerosis focal y segmentaria by Melissa Pilco-Terán, Amir Shabaka, Mónica Furlano, Ana Tato Ribera, Isabel Galán Carrillo, Eduardo Gutiérrez, Roser Torra, Gema Fernández-Juárez

“…Abstract: Focal segmental glomerulosclerosis (FSGS) is a histological pattern of injury that derives from various pathological processes that affect podocytes, resulting in loss of selectivity of the glomerular filtration membrane, proteinuria and the development of renal failure that progresses to end-stage kidney disease in a significant number of patients. …”
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Healthcare practitioners as accomplices: a qualitative study of gender affirmation in a context of ambiguous regulation in Indonesia by Benjamin Hegarty, Alegra Wolter, Amalia Puri Handayani, Kevin Marian, Jamee Newland, Dede Oetomo, Ignatius Praptoraharjo, Angela Kelly-Hanku

“…Conclusions An empirical study based on an “ethics from below” helps to show that arguments grounded in autonomy, or based on biomedical evidence, are unlikely to alter unjust laws or facilitate a change to pathologizing guidelines governing understanding of trans people’s healthcare and legal needs in Indonesia. …”
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Clinicopathological characteristics and survival outcomes of women aged ≤45 and >45 years with endometrial adenocarcinoma in tertiary referral hospital: a 21-year cohort study by Tarinee Manchana, Pinyada Panyavaranant, Juthamas Rattanachaipipat

“…Among the population, 188 patients (16.9%) were ≤45 years old and 926 patients (83.1%) were &gt;45 years old.Outcome measures The primary outcome measures were disease-free survival (DFS) and overall survival (OS) at 5, 10 and 15 years, with an analysis of survival rates based on patient age groups and prognostic factors.Results Younger patients (≤45 years) displayed significantly higher rates of obesity, nulliparity and polycystic ovary syndrome (PCOS), as well as favourable pathological characteristics such as well-differentiated tumours and lower rates of myometrial invasion. …”
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Correction of Dysbiosis in Diversion Proctitis: Possibilities of Intraluminal Sanitation and the Prevention of Complications after Reconstructive Surgery by V. S. Groshilin, D. V. Martynov, Yu. L. Naboka, M. Yu. Bakulyarov, G. A. Mrykhin

“…Rifaximin-α (Alpha Normix®) intolerance and pathological reactions associated with its use were not observed. …”
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