Neuropsychological outcome of indoor rehabilitation in post-COVID-19 condition—results of the PoCoRe study by Michael Jöbges, Melanie Tempfli, Melanie Tempfli, Christoph Kohl, Christoph Herrmann, Stefan Kelm, Alexa Kupferschmitt, Alexa Kupferschmitt, Alexa Kupferschmitt, Ida Montanari, Nike Walter, Gerhard Suetfels, Thomas Loew, Volker Köllner, Volker Köllner, Thilo Hinterberger

“…Furthermore, of the 27% of participants with pathological MoCA scores at admission, 63% improved to normative levels during rehabilitation, indicating a significant treatment effect (p ≤ 0.001). …”
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Mesothelial cell responses to acute appendicitis or small bowel obstruction reactive ascites: Insights into immunoregulation of abdominal adhesion. by Melissa A Hausburg, Kaysie L Banton, Christopher D Cassidy, Robert M Madayag, Carlos H Palacio, Jason S Williams, Raphael Bar-Or, Rebecca J Ryznar, David Bar-Or

“…., acute appendicitis (AA), causes formation of reactive ascitic fluid (rA) that activates peritoneum surface mesothelial cells (MCs) to form adhesions. Pathologic adhesions may arise if restoration of MC-regulated fibrinolysis and secretion of glycocalyx (GCX) are disrupted. …”
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Deep-learning-based extraction of circle of Willis topology with anatomical priors by Dieuwertje Alblas, Iris N. Vos, Micha M. Lipplaa, Christoph Brune, Irene C. van der Schaaf, Mireille R. E. Velthuis, Birgitta K. Velthuis, Hugo J. Kuijf, Ynte M. Ruigrok, Jelmer M. Wolterink

“…The CoW is extensively studied in relation to neurovascular pathologies, with certain anatomical variants previously linked to ischemic stroke and intracranial aneurysms. …”
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Relationship between Blood Lipid Profiles and Risk of Lupus Nephritis in Children by Jiajia Liu, Wenqi Song, Dawei Cui

“…A total of 134 children with newly diagnosed SLE were divided into LN and non-LN groups according to pathological renal biopsy results. Clinical manifestations and blood lipid profiles were analyzed and compared between the two groups, and the relationships between blood lipid profiles and risk of LN were evaluated. …”
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Identifying Risk Factors Associated With False‐Negative Results in US‐Guided Percutaneous Transthoracic Needle Lung Biopsy of Subpleural Pulmonary Lesions by Jiawei Yi, Mengjun Shen, Junhui He, Runhe Xia, Xinyu Zhao, Yin Wang

“…Materials and Methods This ambispective cohort study included patients with subpleural pulmonary lesions who underwent US‐PTLB with benign pathological findings between April 2017 and June 2022 (retrospective cohort) and between July 2022 and October 2022 (prospective cohort). …”
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Relevance of superoxide dismutase type 1 to lipoid pneumonia: the first retrospective case-control study by Yinan Hu, Yanhong Ren, Yinzhen Han, Zhen Li, Weiqing Meng, Yuhui Qiang, Mengyuan Liu, Huaping Dai

“…LP is difficult to differentiate from other similar diseases without pathological evidence, such as upper respiratory tract infection (URTI), pneumonia, cryptogenic organizing pneumonia (COP), pulmonary alveolar proteinosis (PAP), lung mucinous adenocarcinoma and pulmonary edema. …”
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Comparison of clinicopathological characteristics and prognosis between primary squamous cell carcinoma of the thyroid and squamous cell carcinoma combined with papillary thyroid c... by Wanyun Yan, Huiying Chen, Xiaoyu Lin, Ruifa Zhou, Feng Zhao, Jiping Su

“…In addition, the publications in CNKI, Wanfang, VIP, PubMed, Embase, Web of Science, and ProQuest databases were systematically searched to collect patient information. According to pathological diagnosis, patients were divided into the PSCCT and SCC-PTC groups, and compared their clinical characteristics, treatment, and prognosis, respectively.Results308 patients in the PSCCT group and 60 patients in the SCC-PTC group were enrolled in the study. …”
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Comprehensive analysis of causal pathogens and determinants influencing black rot disease development in MD2 pineapples by Manori Kuruppu, Yasmeen Siddiqui, Hala Badr Khalil, Hala Badr Khalil

“…However, postharvest losses due to pathological diseases remain a challenge. Black rot, a major postharvest disease, causes significant economic losses in pineapples. …”
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Gain-of-function ANXA11 mutation cause late-onset ALS with aberrant protein aggregation, neuroinflammation and autophagy impairment by Qing Liu, Ye Sun, Baodong He, Haodong Chen, Lijing Wang, Gaojie Wang, Kang Zhang, Ximeng Zhao, Xinzhe Zhang, Dongchao Shen, Xue Zhang, Liying Cui

“…Both groups exhibited late-onset motor dysfunction at approximately 10 months of age, with similar survival rates to wild-type (> 24 months) and no signs of dementia. Pathological analysis revealed early abnormal aggregates in spinal cord motor neurons, cortical neurons, and muscle cells of homozygous mice. …”
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Emerging PET Radiotracers and Targets for Imaging of Neuroinflammation in Neurodegenerative Diseases: Outlook Beyond TSPO by Vidya Narayanaswami PhD, Kenneth Dahl PhD, Vadim Bernard-Gauthier PhD, Lee Josephson PhD, Paul Cumming PhD, Neil Vasdev PhD

“…On the other hand, chronic neuroglial activation is a major pathological mechanism in neurodegenerative diseases, likely contributing to neuronal dysfunction, injury, and disease progression. …”
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Decreased Gray Matter Volume in the Frontal Cortex of Migraine Patients with Associated Functional Connectivity Alterations: A VBM and rs-FC Study by Zhijian Cao, Wenjing Yu, Zhengxiang Zhang, Maosheng Xu, Jiangnan Lin, Luping Zhang, Wenwen Song

“…However, the pathophysiology and imaging markers specific for migraine pathologies are not well understood. In this study, we combined both structural and functional images to explore the concurrence and process of migraines. …”
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Patients with symptoms of delayed gastric emptying have a high prevalence of oesophageal dysmotility, irrespective of scintigraphic evidence of gastroparesis by George Triadafilopoulos, John O Clarke, Linda Nguyen

“…There was no relationship between oesophageal symptoms and motor or pH abnormalities in either groups.Conclusions Irrespective of gastric emptying delay by scintigraphy, patients with symptoms suggestive of gastric neuromuscular dysfunction have a high prevalence of oesophageal motor disorder and pathological oesophageal acid exposure that may contribute to their symptoms and may require therapy. …”
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Cytoreductive Nephrectomy and Nephrectomy/Complete Metastasectomy for Metastatic Renal Cancer by Paul Russo, Mark Synder, Andrew Vickers, Varuni Kondagunta, Robert Motzer

“…Between July 1989 and September 2003, we queried our department's renal tumor database for patients undergoing cytoreductive nephrectomy alone or in conjunction with complete metastasectomy. Clinical and pathological factors analyzed included primary tumor size, stage and histological subtype, age, gender, Karnofsky Performance Status (KPS) prior to nephrectomy, number and location of metastatic sites, and the presence or absence of any systemic therapy. …”
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Heterogeneity of avian infectious bronchitis virus population by Ye. V. Ovchinnikova, L. O. Scherbakova, S. N. Kolosov, A. N. Andriyasova, N. G. Zinyakov, Z. B. Nikonova, A. A. Kozlov, P. B. Akshalova, D. A. Altunin, D. B. Andreychuk

“…The data obtained indicate that, despite the vaccination used, a genetically diverse population of the infectious bronchitis virus circulates in the poultry farm, while the infection may not manifest itself at an early age, but may affect the flock productivity in the future due to pathological changes in the reproductive organs of laying chickens.…”
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Study on the safety and efficacy of HIFU in the treatment of VaIN by Susu Wu, Xiang Li, Dabao Xu, Mingzhu Ye

“…Purpose This study aimed to investigate the safety and efficacy of High-Intensity Focused Ultrasound (HIFU) treatment for vaginal intraepithelial neoplasia(VaIN).Methods Retrospective analysis was conducted on clinical, pathological, and follow-up data of 43 patients who underwent HIFU treatment for VaIN at Xiangya Third Hospital of Central South University between January 2018 and December 2022. …”
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Effect of Zhuanggu Jianxi Decoction on Synovitis in Knee Osteoarthritis Rabbits via LXRs/NF-κB Pathway by CHEN Peng, GUO Jiemei, XIAO Yan, WANG Jianhui, SU Youxin

“…Compared with the Zhuanggu Jianxi decoction group, the morphological score of pathological changes in the LXRα and N-CoR inhibitor groups was significantly increased (<italic>P</italic>&lt;0.05). 2) Inflammation-related indicators: compared with the blank group after intervention, the contents of IL-1β, TNF-α, MMP-3 and MMP-13 in the model group were significantly increased (<italic>P</italic>&lt;0.05); compared with the model group, the indexes above in the LXRα inhibitor group, N-CoR inhibitor group and Zhuanggu Jianxi decoction group were significantly decreased (<italic>P</italic>&lt;0.05); compared with the Zhuanggu Jianxi decoction group, the indexes above in the LXRα and N-CoR inhibitor groups were significantly increased (<italic>P</italic>&lt;0.05). …”
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Antiedemic Effect of the Myosin Light Chain Kinase Inhibitor PIK7 in the Rat Model of Myocardial Ischemia Reperfusion Injury by Dmitry L. Sonin, Mikhail S. Medved, Asker Y. Khapchaev, Maria V. Sidorova, Marina E. Palkeeva, Olga A. Kazakova, Garry V. Papayan, Daniil A. Mochalov, Sarkis M. Minasyan, Ilya E. Anufriev, Daria V. Mukhametdinova, Natalia M. Paramonova, Ksenia M. Balabanova, Anastasia S. Lopatina, Ilia V. Aleksandrov, Natalya Yu. Semenova, Anna A. Kordyukova, Kirill V. Zaichenko, Vladimir P. Shirinsky, Michael M. Galagudza

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Effect of Xingbi Gel Nasal Drops on Rats with Allergic Rhinitis Based on the Nasal Mucosa-Hippocampus Neuroimmune Mechanism by FAN Xueqi, QIU Caixia, YAN Shuiping, ZHUANG Xiangli, AI Si, GUO Lihua, ZHENG Jian

“…Compared with the model group, IgE and TGF-β1 contents in serum in both the traditional Chinese medicine group and the western medicine group were significantly lower (<italic>P</italic>&lt;0.05). (4) Pathological changes of nasal mucosa and EOS counts: the nasal mucosa in the model group was edematous and the epithelial cells were arranged in disorder; the nasal mucosa edema were alleviated significantly in the traditional Chinese medicine group and the western medicine group after treatment, and the epithelial cell structure was more intact. …”
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Clinical experience with recombinant prourokinase for complex retinal diseases in type 2 diabetes by L.K. Moshetova, Yu.B. Slonimsky, I.V. Vorobyeva, A. Dgebuadze, O.V. Agafonova, E.P. Delver, A.A. Belogurov

“…&nbsp;</i> </p> <p> <b>Conclusion: </b><i>fibrinolytic treatment provided stabilization of pathological process in patients with complex retinal diseases since VEGF-A tear levels did not change significantly. …”
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Defects at the Posttranscriptional Level Account for the Low TCRζ Chain Expression Detected in Gastric Cancer Independently of Caspase-3 Activity by Ana Aguinaga-Barrilero, Patricia Castro-Sánchez, Ignacio Juárez, Alberto Gutiérrez-Calvo, Noelia Rodríguez-Pérez, Adela Lopez, Remedios Gómez, José M. Martin-Villa

“…These results further place the defect responsible for the low TCRζ expression in cancer at the posttranscriptional level and suggests contrary to what has been proposed in other pathologies that elevated caspase-3 activity is not the causative agent.…”
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