A Comparative Evaluation for Biologic Width following Surgical Crown Lengthening Using Gingivectomy and Ostectomy Procedure by Kiran Kumar Ganji, Veena Ashok Patil, Jiji John

“…Surgical crown lengthening has been proposed as a means of facilitating restorative procedures and preventing injuries in teeth with structurally inadequate clinical crown or exposing tooth structure in the presence of deep, subgingival pathologies which may hamper the access for proper restorative measures. …”
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Exploring Azithromycin’s Neuroprotective Role in Traumatic Brain Injury: Insights into Cognitive and Motor Recovery and Neuroinflammatory Modulation by Mohannad A. Almikhlafi, Nehad A. Abdallah, Aakash Kumar, Tarun Sharma, Zuber Khan, Haifa A. Fadil, Sultan Althagfan, Ahmed K. B. Aljohani, Sara A. Almadani, Samar F. Miski, Tahani Saeedi, Rayan S. Alharbi, Abdulrahman M. Al-Harthe, Mohammed H. Alsubhi, Hanaa Wanas, Ahmed Aldhafiri, Sidharth Mehan, Hossein M. Elbadawy

“…Histological assessments revealed enhanced neuronal integrity and fewer pathological changes in AZI-treated rats compared to untreated TBI controls. …”
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Comparison of Oncological Outcomes After Curative Resection for Right-side Colon Cancer and Left-side Colon Cancer: a Retrospective Observational Study by Mehmet Torun, Orhan Uzun, Mustafa Duman, Erdal Polat, Aziz Serkan Senger, Mürşit Dinçer, Ömer Özduman, Selçuk Gülmez, Ahmet Orhan Sunar

“…Conclusion: Despite clinical and pathological differences between RCC and LCC, no significant difference was observed in 2- and 5-year survival. …”
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Deciphering the generation of heterogeneity in esophageal squamous cell carcinoma metastasis via single-cell multiomics analysis by Kaiwen Sheng, Jun Chen, Ruitang Xu, Haoqiang Sun, Ran Liu, Yongjie Wang, Wenwen Xu, Jiao Guo, Miao Zhang, Shuai Liu, Juan Lei, Yawen Sun, Yang Jia, Dianhao Guo

“…Methods We performed single-cell assay for transposase-accessible chromatin sequencing (scATAC-seq) on cancerous and adjacent noncancerous tissues from four ESCC patients who were pathological staged as T1a, T2b, T3b, or T4a, to investigate whether regulatory elements are pivotal in instigating cellular heterogeneity during ESCC metastasis. …”
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A novel biomarker of COVID-19: MMP8 emerged by integrated bulk RNAseq and single-cell sequencing by Zhenguo Liu, Shunda Wang

“…Therefore, a deep understanding of the pathological progression and molecular alteration is an urgent issue for settling the diagnosis and therapy problems of COVID-19. …”
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Joint Group and Multi Institutional Position Opinion: Cirrhotic Cardiomyopathy—From Fundamentals to Applied Tactics by Ivan Rankovic, Ivana Babic, Jelena Martinov Nestorov, Jelena Bogdanovic, Maja Stojanovic, Jovanka Trifunovic, Nikola Panic, Mihailo Bezmarevic, Jelena Jevtovic, Dusan Micic, Vladimir Dedovic, Nemanja Djuricic, Filip Pilipovic, Elena Curakova Ristovska, Tijana Glisic, Sanja Kostic, Nemanja Stojkovic, Nata Joksimovic, Mileva Bascarevic, Aleksandra Bozovic, Lewis Elvin, Ajibola Onifade, Keith Siau, Elizaveta Koriakovskaia, Vladimir Milivojevic

“…However, our group still advocates them as essential tools in optimizing the neurohumoral pathologic axis that perpetuates CCM. Other targeted therapies with direct anti-inflammatory and antioxidative effects still lack sufficient evidence for wide approval. …”
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Correlations among PPAR𝜸, DNMT1, and DNMT3B Expression Levels and Pancreatic Cancer by Valerio Pazienza, Francesca Tavano, Giorgia Benegiamo, Manlio Vinciguerra, Francesca Paola Burbaci, Massimiliano Copetti, Fabio Francesco di Mola, Angelo Andriulli, Pierluigi di Sebastiano

“…In this study we aimed to evaluate the expression of PPARγ, DNMT1, and DNMT3B and their correlation with clinical-pathological features in patients with pancreatic cancer (PC), and to define the effect of PPARγ activation on DNMTs expression in PC cell lines. qRT-PCR analysis showed that DNMT3B expression was downregulated in tumors compared to normal tissues (𝑃=0.03), whereas PPARγ and DNMT1 levels did not show significant alterations in PC patients. …”
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Structure and dynamics analysis of brain functional hypernetworks based on the null models by Chen Cheng, Yao Li, Chunyan Wang, Yanli Yang, Hao Guo

“…Such studies can help to explore how the important functional features of brain functional hypernetworks characterize the working and pathological mechanisms of the human brain. Therefore, this article introduces the hypernetwork null model to analyze the dependencies between the features of interest. …”
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Chat GPT 4o vs residents: French language evaluation in ophthalmology by Leah Attal, Elad Shvartz, Nakhoul Nakhoul, Daniel Bahir

“…ChatGPT 4o demonstrated consistent accuracy over time, with particular strength in the fundamentals of ophthalmology, ocular pathologies, and refractive surgery. Its performance in image processing was significantly improved compared to other chatbots, though still inferior to text-based processing. …”
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Lupeol Attenuates Palmitate-Induced Hypertrophy in 3T3-L1 Adipocytes by Vaithinathan Selvaraju, Shivani R. Babu, Robert L. Judd, Thangiah Geetha

“…These adiposity-associated pathologies can be influenced by dietary components and their potential health benefits. …”
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An Intelligent Medical Imaging Approach for Various Blood Structure Classifications by Madallah Alruwaili

“…Blood is a vital body fluid and can be instrumental in identifying various pathological conditions. Nowadays, a lot of people are suffering from COVID-19 and every country has its own limited testing capacity. …”
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Remote Inflammatory Preconditioning Alleviates Lipopolysaccharide-Induced Acute Lung Injury via Inhibition of Intrinsic Apoptosis in Rats by Yong Liu, Jiahang Xu, Liang Zhao, Jing Cheng, Baojun Chen

“…As inflammation and oxidative stress are the common pathological basis of endotoxin-induced inflammatory injury and ischemic reperfusion injury (IRI), we speculate that remote ischemic preconditioning (RIPC) can be protective for ALI when used as remote inflammatory preconditioning (RInPC). …”
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Complex approach to the prevention and treatment of progressive myopia in school children by Tarutta E.P, Iomdina E.N, Tarasova N.A., Markosyan G.A., Maksimova M.V.

“…With the appointment of an adequate treatment complex, an individual approach is needed that takes into account the child’s health and the functional features of his organ of vision, which will stop the progression of myopia and prevent the development of irreversible pathological changes in the fundus of myopic genesis.…”
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25-Gauge Vitrectomy in Open Eye Injury with Retained Foreign Body by G. Sborgia, N. Recchimurzo, A. Niro, L. Sborgia, A. Sborgia, G. Alessio

“…In the last year small gauge vitrectomy has become safer and more efficient, extending the range of pathologies successfully treated. Aims. To evaluate the safety and outcomes in patients with open eye injury with retained foreign body that underwent early 25-gauge vitrectomy. …”
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Effects of Polystyrene Microplastic Exposure on Liver Cell Damage, Oxidative Stress, and Gene Expression in Juvenile Crucian Carp (<i>Carassius auratus</i>) by Xiangtong Li, Yuequn Huang, Wenrong Li, Chaoyang Deng, Weiyuan Cao, Yi Yao

“…The results demonstrated that: (1) Different concentrations of PS-MPs cause varying degrees of pathological and oxidative damage to liver tissue cells of crucian carp. …”
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Exosomes derived from liver failure patients’ plasma stimulated mesenchymal stem cells alleviate acute liver failure by Zhuoran Wang, Jun Ling, Shaoli You, Bing Zhu

“…Compared to NC-Exos, LF-Exos induced AKT phosphorylation in hepatocytes and liver tissues, inhibited D-GalN/LPS-induced apoptosis in hepatocytes, and reduced pathological liver injury in the mouse model of ALF. …”
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Cognition Deficits in Parkinson’s Disease: Mechanisms and Treatment by Congcong Fang, Longqin Lv, Shanping Mao, Huimin Dong, Baohui Liu

“…In our review, we focus on a description of cognitive decline in PD, expound emphatically the pathological mechanisms underlying cognition deficits in PD, then give a comprehensive overview of specific therapeutic strategies, and finally dissect what fresh insights may bring new exciting prospect for the subfield.…”
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Clinical Presentation and Course of Pulmonary Involvement in Chronic Nonbacterial Osteomyelitis by Toni Hospach, Friederike Blankenburg, Anita Heinkele, Kristina Rücklová, Peter Müller‐Abt, Frank Weller‐Heinemann, Laura Buchtala, Jan Maier, Jasmin Kümmerle‐Deschner, Christiane Reiser, Ales Janda, Andreas Urban, Reiner Berendes, Andrea Skrabl‐Baumgartner, Jürgen Brunner, Ralf Trauzeddel, Johannes Peter Haas, Annette Holl‐Wieden, Henner Morbach, Anja Schnabel, Normi Brück, Gabriele Hahn, Wolfgang Emminger, Isabella Valent, Regine Borchers, Christian Klemann, Ilias Tsiflikas, Jens Klotsche, Kirsten Minden, Christian M. Hedrich, Thekla von Kalle

“…Although prominent hilar lymph nodes were present (in 19% of patients), no pathologic enlargement (>1 cm) was seen. When available (3 of 22 patients), histology revealed granulomatous inflammation with lymphocyte infiltration. …”
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Automated skin melanoma diagnostics based on mathematical model of artificial convolutional neural network by D. A. Gavrilov, E. I. Zakirov, E. V. Gameeva, V. Yu. Semenov, O. Yu. Aleksandrova

“…Among the most promising applica ons: automated recogni on and classifi ca on of skin diseases, detec on of pathologies on X-ray, CT, MRI, ultrasound imaging. In the proposed project, we will focusour a en on on the diagnosis of human skin diseases.At the moment, melanoma is one of the most dangerous types of malignant tumors of the skin with a lot of deaths due to rapid metastasis, which is difficult to treat. …”
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Applications of MR Finger printing derived T1 and T2 values in Adult brain: A Systematic review [version 1; peer review: 2 approved] by Rajagopal Kadavigere, Obhuli Chandran M, Kaushik Nayak, Abhijith S, Saikiran Pendem, Varsha Raghu, Shailesh Nayak S, Riyan Mohamed Sajer, Tancia Pires, Priyanka -

“…With reduced acquisition times, MRF outperforms conventional MRI in detecting subtle pathologies, distinguishing properties, and providing reliable biomarkers.…”
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