Radiomic prediction for durable response to high‐dose methotrexate‐based chemotherapy in primary central nervous system lymphoma by Haoyi Li, Mingming Xiong, Ming Li, Caixia Sun, Dao Zheng, Leilei Yuan, Qian Chen, Song Lin, Zhenyu Liu, Xiaohui Ren

“…Methods A total of 159 patients pathologically diagnosed with PCNSL between 2011 and 2021 across two institutions were enrolled. …”
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[18F]PARPi Imaging Is Not Affected by HPV Status In Vitro by Navjot Guru, Paula Demétrio De Souza França, Giacomo Pirovano, Cien Huang, Snehal G. Patel, Thomas Reiner

“…Human papillomavirus- (HPV-) associated oropharyngeal squamous cell carcinomas (OPSCCs) are clinically and pathologically distinct from HPV-negative tumors. Here, we explore whether HPV affects functional biomarkers, including γH2AX, RAD51, and PARP1. …”
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Early Transcriptional Changes Induced by Wnt/β-Catenin Signaling in Hippocampal Neurons by Eduardo Pérez-Palma, Víctor Andrade, Mario O. Caracci, Bernabé I. Bustos, Camilo Villaman, Matías A. Medina, Miguel E. Ávila, Giorgia D. Ugarte, Giancarlo V. De Ferrari

“…Wnt/β-catenin signaling modulates brain development and function and its deregulation underlies pathological changes occurring in neurodegenerative and neurodevelopmental disorders. …”
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Graphene oxide scaffolds promote functional improvements mediated by scaffold-invading axons in thoracic transected rats by Marta Zaforas, Esther Benayas, Raquel Madroñero-Mariscal, Ana Domínguez-Bajo, Elena Fernández-López, Yasmina Hernández-Martín, Ankor González-Mayorga, Elena Alonso-Calviño, Eduardo R. Hernández, Elisa López-Dolado, Juliana M. Rosa, Juan Aguilar, María C. Serrano

“…Despite outstanding advances in the field to both understand and tackle these pathologies, a cure for SCI patients, with their peculiar characteristics, is still a mirage. …”
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Discovery and in vitro characterization of a human anti-CD36 scFv by Cecilia Mata-Cruz, Cecilia Mata-Cruz, Sandra L. Guerrero-Rodríguez, Keyla Gómez-Castellano, Gregorio Carballo-Uicab, Juan Carlos Almagro, Juan Carlos Almagro, S. Mayra Pérez-Tapia, S. Mayra Pérez-Tapia, S. Mayra Pérez-Tapia, Marco A. Velasco-Velázquez

“…CD36 overexpression favors progression of different pathologies, such as atherosclerosis and cancer. Thus, CD36 targeting has medicinal relevance. …”
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Circadian Clock Gene Bmal1: A Molecular Bridge from AKI to CKD by Songyuan Yang, Zehua Ye, Lijia Chen, Xiangjun Zhou, Wei Li, Fan Cheng

“…In this study, we conducted a retrospective analysis of Bmal1’s role in AKI and CKD, reviewed recent research advancements, and investigated how Bmal1 influences the pathological mechanisms underlying the progression from AKI to CKD. …”
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Exploring Advances in Natural Plant Molecules for Allergic Rhinitis Immunomodulation in Vivo and in Vitro by Li B, Dong B, Xie L, Li Y

“…These treatments have demonstrated efficacy in alleviating clinical symptoms and pathological states. However, with the growing awareness of AR and rising expectations for improvements in quality of life, these treatments have become associated with a higher incidence of side effects and an elevated risk of drug resistance. …”
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Validity of Accelerometers for the Evaluation of Energy Expenditure in Obese and Overweight Individuals: A Systematic Review by Silvia Pisanu, Andrea Deledda, Andrea Loviselli, Inge Huybrechts, Fernanda Velluzzi

“…The following descriptive information was extracted for each study: sample size, characteristics of participants (sex, age, BMI, fat mass percentage, any pathological conditions, modality of recruitment in the study, and exclusion criteria), accelerometer description (model, type and body position), and type of gold standard and validity protocol (duration, conditions, and requirements during and before the experiment). …”
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Profile of Lumbar Spinal Stenosis Patients at Dr. M. Djamil Central Public Hospital from 2018-2022 by Inasa Faiza Akbar, Roni Eka Sahputra, Eka Fithra Elfi, Rizki Rahmadian, Dina Arfiani Rusjdi, Nelmi Silvia

“…Background: Lumbar Spinal Stenosis (LSS) is a pathological condition characterized by narrowing of the spinal canal in the lower back. …”
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Volatile Organic Compounds as Biomarkers of Gastrointestinal Diseases and Nutritional Status by Mariangela Rondanelli, Federica Perdoni, Vittoria Infantino, Milena Anna Faliva, Gabriella Peroni, Giancarlo Iannello, Mara Nichetti, Tariq A. Alalwan, Simone Perna, Clementina Cocuzza

“…New innovative methods have been described that allow the detection and quantification of a broad spectrum of metabolites present in exhaled breath even at very low levels, some of which have been shown to be indicators of pathological conditions. Results. Five studies were analyzed that involved VOC analysis in relation to type of diet. …”
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Study Protocol of the Korean EGFR Registry: A Multicenter Prospective and Retrospective Cohort Study in Nonsmall Cell Lung Cancer Patients With EGFR Mutation by Chang Dong Yeo, Dong Won Park, Seong Hoon Yoon, Eun Young Kim, Jeong Eun Lee, Shin Yup Lee, Chang‐Min Choi, In‐Jae Oh, Do Jin Kim, Jeong Seon Ryu, Jae Cheol Lee, Young‐Chul Kim, Tae Won Jang, Kye Young Lee, Seung Hun Jang, Seung Joon Kim, for the Korean EGFR Registry Investigators

“…Data collection will include patient demographics, smoking history, quality of life assessments, pathological data, and treatment outcomes, with follow‐up until December 2026. …”
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Application of Metagenomic Next-Generation Sequencing in the Diagnosis of Infectious Keratitis by Xin-Yu Pan, Meng Wang, Yi-Dan Xu, Lin-Nong Wang

“…The positivity rates of secretion culture, corneal laser confocal microscopy (CM), mNGS, and pathological sections were 47.3% (133/281), 45.3% (111/245), 83.9% (104/124), and 19.3% (40/207), respectively. …”
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Exploring Liraglutide’s mechanism in reducing renal fibrosis: the Fsp1-CoQ10-NAD(P)H pathway by Qi Chen, Ji-Xian Song, Zhi Zhang, Ji-Ren An, Yu-Jing Gou, Miao Tan, Yashuo Zhao

“…The mice were intraperitoneally injected with LIRA (200 µg/kg/d) daily for 6 weeks. Renal function, pathologic changes, lipid peroxidation levels, iron levels, and ferroptosis were assessed. …”
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Genetic diversity leads to differential inflammatory responses to cigarette smoke in mice by Md Imam Faizan, Gagandeep Kaur, Sadiya Bi Shaikh, Felix Effah, Hoshang Unwalla, Irfan Rahman

“…The UM‐HET3 (HET3) mouse strain, typically used in aging intervention studies, has also been used to evaluate the translatability of this model for age‐associated pathologies. The study involves a comprehensive approach, including BALF cytokine analysis, evaluation of lung tissue architecture, assessment of macrophages and its associated proteins (MMP9 & MMP12) abundance. …”
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Characterization of Novel Nonobese Type 2 Diabetes Rat Model with Enlarged Kidneys by Ayaka Domon, Kentaro Katayama, Yuki Tochigi, Hiroetsu Suzuki

“…Affected males exhibited disorganized architecture of pancreatic islets, decreased numbers of β cells, and markedly decreased expression of insulin, despite no pathological findings of hemorrhage or infiltration of inflammatory cells in the pancreatic islet. …”
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Comparing personality traits of healthcare workers with and without long COVID: Cross‐sectional study by Keiko Sakai, Seiichiro Tarutani, Takehiko Okamura, Hiroshi Yoneda, Tatsuhito Kawasaki, Masatoshi Takeda

“…Abstract Aim Pathological mechanisms of “long COVID” after recovery from the main symptoms of COVID‐19 are unclear. …”
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Correlation between axial and coronal common bile duct diameters in computed tomography: a retrospective study of 1064 patients by Adisak Kasemassawachanont, Natinee Chuangsuwanich, Wanicha Lertpipopmetha, Nutthanun Panrong, Kittipott Thusneyapan, Sasima Tongsai, Napakadol Noppakunsomboon, Rathachai Kaewlai

“…Abstract Background The measurement of the common bile duct (CBD) diameter is essential for evaluating bile duct pathologies. The axial plane of computed tomography (CT) images is the established method for CBD diameter measurement. …”
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Mechanisms of (Fisch.) Bge. var. mongholicus (Bge.) Hsiao (huang qi) and (Oliv.) Diels (dang gui) in Ameliorating Hypoxia and Angiogenesis to Delay Pulmonary Nodule Malignant Tra... by Ying Guo PhD, Peng Yang MS, Zihong Wu PhD, Sanyin Zhang PhD, Fengming You PhD

“…However, current treatments relying on follow-up and surgical excision fail to fully address clinical needs. Pathological angiogenesis plays a pivotal role in supplying oxygen necessary for the progression of PN to LC. …”
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Prospective Randomized Study on the Influence of Myoinositol in PCOS Women Undergoing IVF in the Improvement of Oocyte Quality, Fertilization Rate, and Embryo Quality by Bernd Lesoine, Pedro-Antonio Regidor

“…Polycystic ovarian syndrome (PCOS) is one of the pathological factors involved in the failure of in vitro fertilization (IvF). …”
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Analysis of macular retinal thickness in polyarteritis nodosa using spectral domain optical coherence tomography by Che-Ning Yang, Chia-Ping Chen, Yi-Ting Hsieh

“…Abstract Purpose To identify the macular retinal layer thickness changes in polyarteritis nodosa (PAN) patients without pathological findings appearing in color fundus photography (CFP), and to investigate the correlations with disease durations. …”
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