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12721
Downregulation of TNF-α/TNF-R1 Signals by AT-Lipoxin A4 May Be a Significant Mechanism of Attenuation in SAP-Associated Lung Injury
Published 2019-01-01“…In vivo, AT-Lipoxin A4 significantly decreased pathological scores of the pancreas and lungs and the serum levels of IL-6 and TNF-α. …”
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12722
Spinal cord injury enhances lung inflammation and exacerbates immune response following exposure to LPS
Published 2025-01-01“…Despite this connection, the underlying pathological mechanisms in the lungs post-SCI are not well understood. …”
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12723
Characterization of G2/M checkpoint classifier for personalized treatment in uterine corpus endometrial carcinoma
Published 2025-02-01“…Compared with the subtype C2, the subtype C1 exhibited higher G2MC scores and was associated with faster disease progression, higher clinical staging, poorer pathological types, and lower therapy responsiveness of cisplatin, radiotherapy and immunotherapy. …”
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12724
Food-Induced Adverse Reactions: A Review of Physiological Food Quality Control, Mucosal Defense Mechanisms, and Gastrointestinal Physiology
Published 2025-01-01“…Furthermore, due to the persistent toxicity of harmful food components, the failure of defense mechanisms can also result in pathological effects triggered by food. This article review presents a food quality control framework that aims to clarify how these reactions relate to normal physiological processes. …”
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12725
Impact of Chronic Statins Use on the Development of Esophagitis in Patients with Gastroesophageal Reflux Disease
Published 2019-01-01“…Statins, lipid lowering drugs with a pleiotropic effect, are recently implicated in various pathologies. Nevertheless, the possible impact of statins in esophagitis development has never been assessed. …”
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12726
Assessment of factors implicated in bone fusion after percutaneous endoscopic lumbar intervertebral fusion
Published 2024-11-01“…Methods: This single-center retrospective study reviewed the medical records of 96 patients who underwent single-level PELIF for degenerative pathologies between 2018 and 2020. Fusion was evaluated using thin-slice computed tomography scans at 12 months by 2 independent radiologists and defined as no detectable lucency between bone and graft. …”
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12727
A Nomogram Based on Apelin-12 for the Prediction of Major Adverse Cardiovascular Events after Percutaneous Coronary Intervention among Patients with ST-Segment Elevation Myocardial...
Published 2020-01-01“…Apelin-12 change rate, apelin-12 level, age, pathological Q wave, myocardial infarction history, anterior wall myocardial infarction, Killip’s classification > I, uric acid, total cholesterol, cTnI, and the left atrial diameter were independently associated with MACEs (all P<0.05). …”
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12728
Role of YAP/TAZ in bone diseases: A transductor from mechanics to biology
Published 2025-03-01“…Abnormal YAP/TAZ activity is linked to several bone pathologies, positioning these proteins as promising targets for new treatments. …”
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12729
Risk of adverse cardiovascular events following spinal cord injury in patients with osteoporosis: Real-world evidence
Published 2025-03-01“…Furthermore, mortality risk is higher in individuals with SCI, particularly those with pathological fracture. Subgroup analyses based on sex and age supported these findings. …”
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12730
Acute oral toxicity study of novel polyherbal formulations by using wistar rats and Swiss albino mice as per OECD 425 TG
Published 2025-02-01“…At the end of the study, animals were euthanized by using the CO2 asphyxiation technique and subjected to gross pathological examinations. Results: According to the assessment of the experimental data, the single-dose acute toxicity study of Hydaljss08 and Immunoboost-Tab formulations in mice and rats was fine. …”
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12731
COMPARATION OF MASTOID TRIANGLE AREA MEASUREMENT TECHNIQUES USING VOLUME RENDERING POST PROCESSING AND MULTI PLANAR REFORMATION
Published 2020-11-01“…The number of samples used were 152 raw data of patients with criteria aged 26-65 years and without any pathological changes in the mastoid process area. This research uses simple random sampling technique. …”
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12732
Exploring serum miR-33b as a novel diagnostic marker for hypercholesterolemia and obesity: insights from a pilot case-control study
Published 2025-01-01“…MicroRNAs (miRNAs) are small, conserved, non-coding RNA sequences consisting of approximately 22 nucleotides, playing crucial roles in biological and pathological functions. Among these, miR-33a/b is particularly associated with metabolic diseases, notably obesity and atherosclerosis. …”
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12733
A Novel Capsule Lumbar Interbody Fusion (CLIF) in Treating Foot Drop due to Lumbar Degenerative Diseases: a Prospective, Observational Study
Published 2021-01-01“…Our preliminary study revealed that the axial tension of L5 nerve root may be involved in the pathological mechanism of foot drop. The novel technique of CLIF can shorten the lumbar spine and can be effective and safe for the treatment of foot drop due to lumbar degeneration-related diseases.…”
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12734
Radiological Staging of Thyroid-Associated Ophthalmopathy: Comparison of T1 Mapping with Conventional MRI
Published 2020-01-01“…Accurate staging of patients with thyroid-associated ophthalmopathy (TAO) is crucial for clinical decision. Full cognition of pathologic changes and staging TAO using conventional T2-weighted imaging is still limited. …”
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12735
B-cell non-Hodgkin's lymphoma in the patient with chronic hepatitis C and mixed cryoglobulinemia
Published 2015-03-01“…At US of the chest soft tissues and anterior abdominal wall no pathological mass lesions were revealed, at investigation of abdominal organs and retroperitoneum no lymph nodes were visualized.Conclusions. …”
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12736
The effects of Fraxini cortex and Andrographis herba on Escherichia coli-induced diarrhea in chicken
Published 2025-02-01“…The findings indicated that Fraxini cortex and Andrographis herba dramatically lowered mortality rates and alleviated pathologic changes in cases of avian E. coli diarrhea (P < 0.05). …”
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12737
Apoptotic PET Imaging of Rat Pulmonary Fibrosis With [F]ML-8
Published 2018-10-01“…In BLM-treated rats, the lung to muscle relative uptake ratio of [ 18 F]ML-8 was also higher than that of [ 18 F]FDG ( P < .05). Pathological examination showed overproliferation of fibroblasts and deposition of collagen in lungs from BLM-treated rats. …”
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12738
Topical issues of drug addiction criminological characteristics in Ukraine
Published 2023-07-01“…In the course of drug addiction, a pathological dependence on any narcotic substance develops, which is accompanied by physical and mental addiction to the drug, which in turn negatively affects the psychophysiological functioning of the body. …”
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12739
NADPH Oxidase 2-Mediated Insult in the Auditory Cortex of Zucker Diabetic Fatty Rats
Published 2019-01-01“…However, mechanisms underlying pathologic changes that occur in the auditory system, especially in the central auditory system (CAS), remain poorly understood. …”
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12740
Clinical characteristics, metastasis patterns, and treatment outcomes of HER2-low breast cancer
Published 2025-02-01“…HER2-positive showed worse MFS, RFS, and OS than HER2-zero and HER2-low subtypes. Pathological complete response (pCR) rates after neoadjuvant chemotherapy were highest in HER2-positive. …”
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