Changes in tear cytokine and lactoferrin levels in postmenopausal women with primary acquired nasolacrimal duct obstruction complicated with obstructed meibomian gland dysfunction by Haili Jin, Xianjie Chen, Feng Ji, Yin Liu, Yonghong Sheng, Guoping Wang, Linfeng Han, Xiaohu Wang, He Ding, Jing Liu, Qingqing Fu

“…We aimed to investigate the changes in tear cytokine and lactoferrin levels in postmenopausal women with primary acquired nasolacrimal duct obstruction (PANDO) complicated with obstructed meibomian gland dysfunction (OMGD) and preliminary explore the pathological mechanisms of OMGD in patients with PANDO. …”
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Evaluating Electrochemical Marker for Udavarta (Slow Transit Constipation) and Risk of Cardiovascular Events: A Cross-Sectional Study by Divya Kajaria, Punam N. Khobarkar

“…To evaluate the association between Udavarta (STC), changes in lead III of ECG, and heart disease score to demonstrate the earliest pathological changes in the heart. A cross-sectional observational study using a survey method to collect data from November 11, 2021 to January 5, 2022. …”
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Hydroxychloroquine Potentiates Apoptosis Induced by PPARα Antagonist in 786-O Clear Cell Renal Cell Carcinoma Cells Associated with Inhibiting Autophagy by Ruizhe Mao, Jian Shi, Xuyi Ma, Haiyan Xu

“…Clear cell renal cell carcinoma (ccRCC) is the major pathological pattern of renal cell carcinoma. The ccRCC cells exhibit a certain degree of inherent drug resistance due to some genetic mutations. …”
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Association of Antibiotic Route and Outcomes in Children with Methicillin-Resistant Staphylococcus aureus Bacteremic Osteomyelitis by Jared Olson, Rana F. Hamdy, Alice J. Hsu, Pranita D. Tamma, Jeffrey S. Gerber, Nora F. Fino, Adam L. Hersh

“…The primary outcome was treatment failure within 6 months of discharge, defined as any of the following: diagnosis of chronic osteomyelitis, conversion from oral to IV antibiotic route, an operative procedure after the index hospitalization (abscess drainage, bone biopsy, arthrocentesis, or pathologic fracture) and/or recrudescence of MRSA bacteremia. …”
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New treatment options for generalized myasthenia gravis by Antanas Vaitkus, J. Čiauškaitė, M. Malakauskaitė, M. Baublytė

“…Myasthenia gravis is an autoimmune disease in which autoantibodies against the postsynaptic membrane proteins of the neuromuscular junction disrupt impulse transmission thus causing pathological muscle weakness and fatigue that worsens throughout the day. …”
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Gut–brain axis and neuropsychiatric health: recent advances by Ceymi Doenyas, Gerard Clarke, Renáta Cserjési

“…Recent studies have underscored the role of the gut microbiome in conditions such as Parkinson’s disease (PD), with evidence indicating that gut dysfunction and pathological features can precede motor symptoms by decades. …”
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Phytocannabinoids: a new frontier in Alzheimer’s disease management by Jagadeesh S. Rao

“…Multiple preclinical studies conducted on animal models of AD have shown that THC specifically targets and modifies the pathological markers of AD while simultaneously enhancing cognitive function. …”
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Primary cardiac lymphoma: a clinicopathological study of 121 cases by Shuhui Zhuang, Liudi Chang, Liudi Chang, Xiaoxi Feng, Xiaoxi Feng, Weiwen Hu, Weiwen Hu, Zhaobo Yang, Yuanyuan Zhang

“…Echocardiography served as the primary diagnostic method in 92.6% of cases, while a definitive diagnosis was achieved through pathological examination in all cases (100%). Treatment strategies predominantly included surgical intervention (44.6%) and chemotherapy (76.0%). …”
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655Val and 1170Pro ERBB2 SNPs in Familial Breast Cancer Risk and BRCA1 Alterations by Stefania Tommasi, Vita Fedele, Rosanna Lacalamita, Michele Bruno, Francesco Schittulli, David Ginzinger, Gery Scott, Serenella Eppenberger-Castori, Daniele Calistri, Silvia Casadei, Ian Seymour, Salvatore Longo, Gianluigi Giannelli, Brunella Pilato, Giovanni Simone, Christopher C. Benz, Angelo Paradiso

“…The aim of this study was to investigate the association of rare alleles of both SNPs and the risk of developing breast cancer, BRCA1 alterations and clinical-pathological features of Caucasian breast cancer patients with familial history of breast/ovarian cancer. …”
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The Association between Platelet Glycocalicin and High Microsatellite Instability in Colorectal Cancer by Zeng-yao Liu, Qing-chun Jia, Wen Wang, Yu-xi Liu, Rui-tao Wang, Jia-yu Li

“…The glycocalicin levels were measured with an enzyme-linked immunosorbent assay, and the cut-off point was determined with the receiver-operating characteristics curve. The clinical and pathological characteristics were collected via electronic medical records. …”
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Voluntary isometric contractions at maximal shortening as a new technique to achieve neuromuscular re-education in healthy subjects by Julio-Artemi Hernández-Trujillo, María-Dolores González-Rivera, Jorge M. González-Hernández

“…Background: objectives: Neuromuscular re-education has focused on improving motor activities in patients with pathologies by retraining the nervous system. However, this has not yet been investigated in healthy individuals. …”
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Evaluation of the Proximity of Root Apices of Maxillary Posterior Teeth to the Maxillary Sinus Floor using CBCT among Different Age Groups: A Retrospective Study by Nadia Rasool, S. Vidhyadhara Shetty, Sajad A. Buch, Prathap MS Nair, S Kalaichelvan, Nishi Jayasheelan

“…Aim: The increased thickness of the Schneiderian membrane under pathological conditions may result in a thickness of up to 3 mm, thereby making it evident on the radiograph. …”
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Interleukin-6 related signaling pathways as the intersection between chronic diseases and sepsis by Jie Yang, Lin Yang, Yanjiao Wang, Lu Huai, Bohan Shi, Di Zhang, Wei Xu, Di Cui

“…In PubMed and Google Scholar, the studies were searched out, which correlating to IL-6 related pathways and associating with the pathological process of sepsis. Focused on the interactions of sepsis and IL-6 related pathways, some chronic diseases have been studied for association with sepsis, containing insulin resistance, Alcoholic liver disease (ALD), Alzheimer disease (AD), and atherosclerosis. …”
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Glucose-6-Phosphate Dehydrogenase Deficiency and Sickle Cell Trait among Prospective Blood Donors: A Cross-Sectional Study in Berekum, Ghana by Patrick Adu, David Larbi Simpong, Godfred Takyi, Richard K. D. Ephraim

“…Screening for red cell pathologies must be incorporated into existing protocols for populations with high incidence of haemoglobinopathies to protect high-risk recipients.…”
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The Role of Anatomical Imaging and Intraoperative Neuromonitoring (IONM) for Successful Prediction of a Nonrecurrent Laryngeal Nerve by Hiroki Kuwazoe, Keisuke Enomoto, Daichi Murakami, Naoko Kumashiro, Saori Takeda, Muneki Hotomi

“…After complete dissection of right thyroid lobe, we again stimulated the NRLN by 0.5 mA and the electromyographic response was confirmed. The pathological analysis confirmed nodular hyperplasia without malignancy; the condition was diagnosed as an adenomatous goiter. …”
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Topography and dimensions of the auditory tube at the end of the fetal period by O.D. Sapunkov, L.O. Bogdanova, A.L. Kosakovskyi, I.A. Kosakivska, V.V. Syniachenko

“…This often leads to the development of pathological changes in the hearing organ and the need for surgical intervention. …”
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PROTEOMIC PROFILING OF BLOOD-BASED BIOMARKERS IN THE EARLY DETECTION OF ALZHEIMERS DISEASE by Syeda Uroosa Hashmi, Fahad Farooq Lasi

“…Now AD is considered a chronic disease which progresses slowly with the consequences of various complex pathologies. AD is linked directly to the amyloid-beta peptides. …”
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Reconstruction of Alzheimer’s Disease Cell Model In Vitro via Extracted Peripheral Blood Molecular Cells from a Sporadic Patient by Sijun Liu, Yuying Zhao, Xiaoying Su, Chengcheng Zhou, Peifen Yang, Qiusan Lin, Shijun Li, Hanxu Tan, Qi Wang, Changjun Wang, Qingguang Wu

“…In conclusion, this study has successfully generated an AD cell model with pathological features of beta-amyloid peptide deposition using PBMC from a patient with sAD.…”
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Characterization of Pregnant Women with Heart Disease at the “Ramón Gonzalez Coro” Gynecologic and Obstetric Teaching Hospital by Yanara Gutierrez Aliaga, Ileana Chio Naranjo, Elena Guerra Chang, Marlén Rodríguez Jorge, Mario Joel Arroyo Díaz, Mayelin Díaz Gutiérrez

“…<strong>Introduction:</strong> pregnancy-related heart disease is nowadays the first cause of maternal morbidity and mortality among pregnancy-related pathologies. <br /><strong>Objective:</strong> to characterize pregnant women with heart disease according to demographic and clinical features. …”
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Advancing Alzheimer’s Diagnosis: The Role of AI - A Review by Dominka Rehan, Sven Solisch, Anna Blazhkova, Anna Susłow, Adam Szwed, Ewa Szczęsna

“…However, theories of neurodegeneration related to the deposition of pathological proteins in the brain and the imbalance between individual neurotransmitters have allowed the development of effective diagnostic methods - laboratory determination of specific biomarkers (tau protein, β-amyloid) and their marking using PET (Amyloid PET, Tau PET). …”
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