Prevalence and risk factors of teat end hyperkeratosis in cows from the Urals region of Russia by A.S. Barkova, V.V. Verkhoturov

“…Analysis of morbidity in farms with different levels of milk productivity showed that as animal productivity increases, more teats with signs of pathological changes are registered. Simultaneously, teat lesions are also observed when using robotic milking machines, but in smaller numbers. …”
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Endoplasmic Reticulum Stress: Its Role in Disease and Novel Prospects for Therapy by Axel H. Schönthal

“…A number of physiological and pathological conditions, as well as a variety of pharmacological agents, are able to disturb proper ER function and thereby cause ER stress, which severely impairs protein folding and therefore poses the risk of proteotoxicity. …”
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Study on the Nomogram Model Based on Dual-energy Computed Tomography for Predicting Lymph Node Metastasis in Papillary Thyroid Carcinoma by Bo GAO, Jingbin ZHANG, Huizhi MI, Haiqiao SUN, Xiaohui LI, Jiaxing WU, Kexin ZHANG, Shaotong WANG, Xuan SU, Xinyue CUI

“…Each patient underwent preoperative neck dual-energy-enhanced CT, and postoperative pathological results revealed 105 lymph nodes as metastatic and 136 as non-metastatic. …”
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Pediatric pancreatic acinar cell carcinoma with a non-canonical BRAF-KMT2C fusion and a classic SND1-BRAF fusion: a case report and literature review by Yaqin Wang, Jiasi Zhang, Dimin Nie, Ai Zhang, Qun Hu, Aiguo Liu

“…Case presentation We report a case of pediatric PACC in a 7-year-old male presenting with a large, non-tender abdominal mass (11 cm x 11 cm) on the right side. Pathological and imaging evidence confirmed the diagnosis of PACC, with no lymph node infiltration or distant metastasis. …”
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Neoadjuvant Endocrine Therapy Compared to Neoadjuvant Chemotherapy in Node-Positive HR+, HER2− Breast Cancer (Nodal pCR and the Rate of ALND): A Systematic Review and Meta-Analysis... by Mahtab Vasigh, Mohammadreza Karoobi, Austin D. Williams, Fasika Molla Abreha, Richard J. Bleicher, Seyed Mostafa Meshkati Yazd, Tahereh Shamsi, Ramesh Omranipour, Ahmad Elahi, David Farhat, Mehran Habibi

“…We evaluated the node pathologic complete response (pCR) and axillary lymph node dissection (ALND) rates after neoadjuvant endocrine therapy (NET). …”
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Point prevalence survey of antibiotics in a pediatric tertiary hospital in the Republic of Panama by Ximena Norero, Dora Estripeaut, Elizabeth Castaño, Jacqueline Levy, Paola Lichtenberger, José Pablo Díaz-Madriz, José Luis Bustos, Robin Rojas Cortés, Gabriel Levy-Hara

“…The findings suggest it is necessary to assess the need for ampicillin, gentamicin, and piperacillin-tazobactam use in patients admitted to pediatric critical care units, with special emphasis on children with pneumonia and sepsis diagnosis, the most common pathologies for which an antimicrobial was prescribed.…”
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Research of Osteoarthritis Based on the Academic Thought of Chen Keji by Xianxiang LIU

“…Objective:To dig, inherit and carry forward the academic thought of Chen Ke-ji in the treatment of osteoarthritis, and then explore the core pathogenesis and treatment concept of osteoarthritis.Methods:Carrying out the basic theory, clinical application and development research by reading scholarly works, such as Medical Selection of Chen Keji, Academic Thought and Medical Record of Chen Keji, Medical Records of Qing Dynasty Palace, listening to Chen Keji's words.Results:(1) The basic pathological characteristics of osteoarthritis are articular cartilage degeneration, hyperosteogeny is followed by. …”
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Unique Biomarker Characteristics in Gestational Diabetes Mellitus Identified by LC-MS-Based Metabolic Profiling by Xingjun Meng, Bo Zhu, Yan Liu, Lei Fang, Binbin Yin, Yanni Sun, Mengni Ma, Yuli Huang, Yuning Zhu, Yunlong Zhang

“…In addition, we provide a critical insight into the pathological and biological mechanisms for GDM.…”
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MYH9 promotes malignant progression of glioma cells through regulating β-catenin stability via epithelial-mesenchymal transition signaling pathway by Zigui Chen, Chao Liu, Wei Zheng, Zhilong Li, Yuanhui Tang, Jun Peng, Changfeng Miao, Dandan Zheng, Ying Xia

“…EMT is involved in multiple physiological and pathological processes in the human body. The occurrence of EMT involves many signal transduction pathways and complex molecular mechanisms related to calnexin, growth factors, transcription factors, and the microenvironment. …”
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Deep learning and radiomics for gastric cancer serosal invasion: automated segmentation and multi-machine learning from two centers by Hui Shang, Tao Feng, Dong Han, Fengying Liang, Bin Zhao, Lihang Xu, Zhendong Cao

“…Methods This study enrolled 311 patients from two centers with pathologically confirmed of GC. we employed a deep learning model, U-Mamba, to obtain fully automatic segmentation of the spleen CT images. …”
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Monascus red pigment influence on hydroxyapatite nanoparticles-mediated renal toxicity in rats by Nasser N. Alqurashy, Mokhtar I. Yousef, Ahmed A. Hussein, Maher A. Kamel, Abeer El Wakil

“…Moreover, an increase in inflammatory (TNF-α and TGF-β) and apoptotic (caspace-3) markers, an elevation in gene-based kidney injuries markers (Kim-1 and lipocalin-2), and pathological tissue changes were determined. Meanwhile, co-treatment with different doses of biopigment and HANPs have reduced oxidative stress via their potent antioxidant effect. …”
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Immunogenic characteristics of <i>Avibacterium paragallinаrum</i> (serogroup B) isolates and strains by M. S. Firsova, V. A. Yevgrafova, A. V. Potekhin, R. V. Yashin, O. V. Pruntova, V. S. Russaleyev

“…The paper presents the results of tests for immunogenic properties of antigens of 13 infectious coryza isolates recovered from the pathological material delivered to the FGBI “ARRIAH” from poultry farms of the Russian Federation and the Republic of Belarus. …”
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SHMT2 Overexpression Predicts Poor Prognosis in Intrahepatic Cholangiocarcinoma by Shanglei Ning, Siquan Ma, Abdul Qahar Saleh, Lingyu Guo, Zixiao Zhao, Yuxin Chen

“…Furthermore, SHMT2 level was closely associated with tumor T stage (P=0.017) and tumor TNM stage (P=0.041) in patients with iCCA, but not with age, gender, tumor size, tumor number, pathological grade, vascular invasion, or N stage. Moreover, Kaplan-Meier analysis suggested that patients with lower SHMT2 level have longer survival rate than those with high expression (45.8 vs 23.1%, P=0.030). …”
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Shedding light on DNA methylation and its clinical implications: the impact of long-read-based nanopore technology by Alexandra Chera, Mircea Stancu-Cretu, Nicolae Radu Zabet, Octavian Bucur

“…Abstract DNA methylation is an essential epigenetic mechanism for regulation of gene expression, through which many physiological (X-chromosome inactivation, genetic imprinting, chromatin structure and miRNA regulation, genome defense, silencing of transposable elements) and pathological processes (cancer and repetitive sequences-associated diseases) are regulated. …”
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Prevalence of low bone mineral density in ankylosing spondylitis, correlation with disease activity, and serum sclerostin levels by Anupam Wakhlu, Akhil Pawan Goel, Puneet Kumar

“…Background: Ankylosing spondylitis (AS) involves pathological new bone formation in the cortical zone of vertebrae and excessive loss of trabecular bone in the center of the vertebral body causing osteoporosis (OP). …”
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BVDV comprehensive studies and species identification in high-yielding livestock populations in the Sverdlovsk Oblast by N. A. Bezborodova, V. V. Kozhukhovskaya, E. V. Pechura, N. A. Martynov, O G. Tomskikh, A. N. Vasilyeva

“…The BVDV RNA, Mycoplasma bovis and Chlamydophila pecorum DNAs were detected simultaneously in 44% of vaginal swab samples from aborted cows and, in single cases, in the placenta and parenchymatous organs of dead calves; BVDV RNA and Bovine herpesvirus type 1 DNA were detected in 16% of pathological samples from dead calves. In some cases, the BVDV RNA, Chlamydophila pecorum and Mycoplasma bovigenitalium DNA were detected in nasopharyngeal swabs of calves. …”
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Altered Brain Structural Networks in Patients with Brain Arteriovenous Malformations Located in Broca’s Area by Maogui Li, Pengjun Jiang, Jun Wu, Rui Guo, Xiaofeng Deng, Yong Cao, Shuo Wang

“…Our preliminary findings contribute extra insights into the understanding of brain plasticity and pathological state in patients with AVMs.…”
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Serum microRNAs as Diagnostic Markers in Polycystic Ovary Syndrome: A Narrative Review by K Lavanya, N Palaniappan, VM Vinodhini, Santhi Silambanan

“…It has been discovered that the altered pattern of microRNAs under pathological circumstances is specific to certain disorders. …”
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Macro-anatomic, cross-sectional anatomic, and computerized tomographic examination of anal region in dogs by Cüneyt Tunahan Maviş, Memduh Gezici

“…<p> <b>Conclusion:</b> The contribution of this study is important for development of diagnostic and treatment methods in approaches to be exhibited especially towards pathological and clinical cases such as perineal hernia, rectal prolapse, urethrotomy, anal sac inflammation and fistulae.…”
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Determination of Mammalian Target of Rapamycin Hyperactivation as Prognostic Factor in Well-Differentiated Neuroendocrine Tumors by G. Lamberti, C. Ceccarelli, N. Brighi, I. Maggio, D. Santini, C. Mosconi, C. Ricci, G. Biasco, D. Campana

“…We evaluated clinical, pathological, and immunohistochemistry features for association with the presence of advanced disease at diagnosis and disease relapse in patients who have undergone radical surgery. …”
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