Laryngeal Carcinoma Characteristics Associated with Positive Margins and Endoscopic Understaging by Nia Labaš, Andro Košec, Mirta Peček, Tomislav Gregurić, Siniša Stevanović

“…<b>Conclusions</b>: The study highlights several clinical and pathological factors associated with positive margins and endoscopic understaging in laryngeal carcinoma. …”
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A CFA-Induced Model of Inflammatory Skin Disease in Miniature Swine by Nalú Navarro-Alvarez, Beatriz M. M. Gonçalves, Alec R. Andrews, David H. Sachs, Christene A. Huang

“…In addition, the side effects of CFA injections were evaluated based on clinical findings, behavioral changes, physiologic state, and (histo)pathologic lesions. Pigs were injected with CFA at the back of the neck’s skin at different depths. …”
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COVID-19 and the Black Death: Nutrition, frailty, inequity, and mortality by Katherine D. VAN SCHAIK, Sharon N. DeWITTE

“…During the Black Death, people with pathological indicators that can reflect undernourishment due to inadequate caloric intake were more likely to die of plague. …”
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The human‐specific noncoding RNA RP11‐424G14.1 functions at the intersection of sexually dimorphic pathways in inflammation, senescence, and metabolism by Kameron Kennicott, Yun Liang

“…Abstract Sexual dimorphism is a fundamental characteristic of various physiological and pathological processes in humans, including immune responses, senescence, and metabolism. …”
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Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis by Shumin Zhao, Shumin Zhao, Ranran Chen, Ranran Chen, Yi An, Yali Zhang, Yali Zhang, Cheng Ma, Ying Gao, Ying Gao, Yanchao Lu, Yanchao Lu, Fei Yang, Fei Yang, Xue Bai, Xue Bai, Jingjing Zhang, Jingjing Zhang, Jingjing Zhang

“…The phenotype onset date, life span, locomotor activity, and pathological changes in the spinal cord were determined and recorded subsequently. …”
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Effects of ALA-PDT on the murine footpad model of Fonsecaea monophora infection and its related mechanisms in vivo by Xuelin Wu, Wenyi Chen, Muhammad Danish Yaqoob, Kangxing Liu, Yanqing Hu, Yan Lu, Yongxuan Hu

“…Results: : ALA-PDT reduced infected footpad volume, fungal burden, and pathological inflammatory infiltration in vivo. It also increased the expression of Marco in the murine infection model. …”
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Proteomic Analysis Reveals the Vital Role of Synaptic Plasticity in the Pathogenesis of Temporal Lobe Epilepsy by Xu Qian, Ji-Qiang Ding, Xin Zhao, Xin-Wen Sheng, Zhao-Rui Wang, Qi-xing Yang, Jing-Jun Zheng, Jia-Gui Zhong, Teng-Yue Zhang, Shu-Qiao He, Wei-Dong Ji, Wei Li, Mei Zhang

“…In the present study, a lithium-pilocarpine-induced TLE model was employed to reveal the pathological changes of hippocampus in rats. Hippocampal samples were taken for proteomic analysis at 2 weeks after the onset of spontaneous seizure (a chronic stage of epileptogenesis). …”
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Pembrolizumab with external radiation therapy effectively controlled TMB-high unresectable recurrent parathyroid cancer: a case report with review of literature by Hiroshi Katoh, Tomoya Mitsuma, Riku Okamoto, Kanako Naito, Takaaki Tokito, Mariko Kikuchi, Takafumi Sangai

“…A 48-year-old male patient, with previous history of left single parathyroidectomy for primary hyperparathyroidism, underwent surgeries for recurrent hyperparathyroidism at 47 and 48 years of age, and was pathologically diagnosed with PC. He was referred to our hospital due to persistent hypercalcemia and elevated PTH. …”
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Outcome and Complications of Combined Phacoemulsification and 23-Gauge Pars Plana Vitrectomy by Selcuk Sizmaz, Ebru Esen, Puren Isik, Burcu Cam, Nihal Demircan

“…Phacoemulsification combined with PPV is a safe and efficient way of management in cases where cataract coexists with vitreoretinal pathologies.…”
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Risk Factors for Amputation in the Surgical Treatment of Hemophilic Osteoarthropathy: A 20-Year Single-Center Report by Yiming Xu, Bin Feng, Wei Zhu, Yingjie Wang, Xisheng Weng

“…The reasons of amputation contained severe pseudotumor with factor inhibitor and large bone defects, recurrent pathological fracture with pseudotumor, skin ulcer with chronic osteomyelitis, and pseudotumor with systematic infection. …”
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Influence of age, sex, and presence of cleft lip and palate on the quantity and quality of saliva-derived DNA by Lina M. Escobar, Zita Bendahan, Deisy Abril, David Díaz-Baez, Adolfo Paternina, Farith González-Martinez, Ma Clara González-Carrera

“…The quantity and quality of DNA are crucial factors in determining polymorphisms in samples from individuals with and without pathologies such as cleft lip and palate (CL/P). Saliva is increasingly being evaluated as a collection method. …”
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Post-chemoradiotherapy adjuvant chemotherapy of rectal cancer by E. V. Ledin, A. V. Kochatkov

“…The decision to prescribe adjuvant chemotherapy seems to be correct in relation to pathologic study results and degree of preoperative chemoradiotherapy response.…”
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Identified VCAM1 as prognostic gene in gastric cancer by co-expression network analysis by Wenjuan Li, Hong Gao, Jianjun Liu

“…Data from RNA sequencing and clinical pathological details were acquired from The Cancer Genome Atlas (TCGA) database and the Gene Expression Omnibus (GEO) dataset. …”
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In silico evaluation of missense SNPs in cancer-associated Cystatin A protein and their potential to disrupt Cathepsin B interaction by Shafaat Hossain, Omar Hamza Bin Manjur, Mst Sharmin Sultana Shimu, Tamanna Sultana, Mustafizur Rahman Naim, Shahariar Siddique, Abdullah Al Mamun, Md Miftaur Rahman, Md Abu Saleh, Md Rakibul Hasan, Tania Rahman

“…These findings suggest that the E94K mutation could affect the protein structure and cathepsin B interaction, potentially leading to pathological consequences as evidenced by colorectal adenocarcinoma patients in the COSMIC (Catalogue of Somatic Mutations in Cancer) database.…”
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Hyperthermia and targeting heat shock proteins: innovative approaches for neurodegenerative disorders and Long COVID by David M. Smadja, David M. Smadja, M. Marc Abreu, M. Marc Abreu

“…HSPs such as HSP70 and HSP90 play pivotal roles in protein folding, aggregation prevention, and cellular protection, directly targeting pathological processes seen in NDs like Alzheimer's, Parkinson's, and Huntington's disease. …”
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Gut microbial subtypes and clinicopathological value for colorectal cancer by Shuwen Han, Jing Zhuang, Yifei Song, Xinyue Wu, Xiaojian Yu, Ye Tao, Jian Chu, Zhanbo Qu, Yinhang Wu, Shugao Han, Xi Yang

“…., free fatty acids and total cholesterol) and CRC pathological information (e.g., tumor depth) varied among gut microbial subtypes. …”
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Dexmedetomidine alleviates acute kidney injury in a rat model of veno‐arterial extracorporeal membrane oxygenation by Min Yu, Shilin Wei, Xueyang Shen, Junjie Ying, Dezhi Mu, Xiangyang Wu, Yongnan Li

“…Immunohistochemical staining was used to evaluate neutrophil infiltration in the kidney. Results The pathological Paller score was substantially lower in the ECMO + DEX group. …”
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Pathogenicity of tick-derived lymphocytic choriomeningitis virus in BALB/c mice by Ziyan Liu, Xiaojie Liang, Liang Li, Ning Liu, Zedong Wang, Feng Wei

“…A total of 16 amino acid substitutions were identified in the L, Z, and GPC proteins between the original JX14 strain and the strain obtained after six months of infection in BALB/c mice. Pathological lesions were identified in most organs within 5 dpi except for the kidneys and testicles. …”
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Prevalence of supernumerary teeth among a sample of patients attending college of dentistry in Erbil, Iraq by Fighan Jalal Hussein, Heran Ibrahim Hassan, Alaa Mahmud Mustafa

“…Conclusion: The identification of this anomaly provides a clue towards the possibility of any complication, pathologies, other related dental anomalies, syndromes and familial association in Erbil, Iraq. …”
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A New Method of Evaluating the Symmetry of Movement Used to Assess the Gait of Patients after Unilateral Total Hip Replacement by Slawomir Winiarski, Alicja Rutkowska-Kucharska, Andrzej Pozowski, Krzysztof Aleksandrowicz

“…Regions of the greatest asymmetry in pathological movements are usually different from the region of the greatest range of motion. …”
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