Predicting high sensitivity C-reactive protein levels and their associations in a large population using decision tree and linear regression by Somayeh Ghiasi Hafezi, Toktam Sahranavard, Alireza Kooshki, Marzieh Hosseini, Amin Mansoori, Elham Amir Fakhrian, Helia Rezaeifard, Mark Ghamsary, Habibollah Esmaily, Majid Ghayour-Mobarhan

“…Abstract High-sensitivity C-reactive protein (hs-CRP) is a biomarker of inflammation predicting the incidence of different health pathologies. In this study, we aimed to evaluate the association between hematological and demographic factors with hs-CRP levels using decision tree (DT) and linear regression (LR) modeling. …”
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“A quality of heart, of presence, and of really caring”: toward affirmative intersex health communication in Canada by Terese Knoppers, Angelica Voutsinas, Nicole Palmour, Kaleb Saulnier, Kaleb Saulnier, Morgan Holmes, Marilou Charron, Hortense Gallois, Hortense Gallois, Narges Jamali, Narges Jamali, Leslie Ordal, Yann Joly

“…They also connected broader societal stigma and pathologization to harmful medical practices and called for naturalization and normalization of intersex variations.ConclusionThis study highlights the need for collaborative efforts across multiple sectors and by multiple stakeholders to drive meaningful change. …”
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A convolutional autoencoder framework for ECG signal analysis by Ugo Lomoio, Patrizia Vizza, Raffaele Giancotti, Salvatore Petrolo, Sergio Flesca, Fabiola Boccuto, Pietro Hiram Guzzi, Pierangelo Veltri, Giuseppe Tradigo

“…The trained framework has been tested on 12 lead ECG signals on a benchmark dataset and applied in scenarios where anomalies are related to cardiological risks and pathologies. The results show interesting results in automatic anomaly detection to support physicians in the decision process. …”
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THE ROLE OF BLACK TEA AND PINEAPPLE JUICE AS NEGATIVE ORAL CONTRASTS ON MAGNETIC RESONANCE CHOLANGIOPANCREATOGRAPHY (MRCP) EXAMINATION by Shinta J. Hapsari, Risalatul Latifah, Muhaimin Muhaimin

“…Background: Magnetic resonance cholangiopancreatography examination is a superior examination in the detection of anatomic structures or pathological abnormalities in the human pancreatobiliary system. …”
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Hyaluronic acid-curcumin nanoparticles for preventing the progression of experimental autoimmune uveitis through the Keap1/Nrf2/HO-1 signaling pathway by Weiwei Tang, Xiaomin Huang, Yun-Di Yi, Fan Cao, Manli Deng, Jiawei Fan, Zheng-Xuan Jiang, Li-Ming Tao, Xianwen Wang, Lei Shi

“…Further in vitro and in vivo experimental results validated the protective function of HA-CUR NPs against oxidative stress-induced damage and inflammatory responses, attenuated pathological progression, relieved microvascular damage, and regulated fundus blood flow in retinal vascular networks. …”
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Identification of TUBB3 as an immunotherapy target in lung cancer by genome wide in vivo CRISPR screening by Dan Zhao, Ravindra Deshpande, Kerui Wu, Abhishek Tyagi, Sambad Sharma, Shih-Ying Wu, Fei Xing, Stacey O'Neill, Jimmy Ruiz, Feng Lyu, Kounosuke Watabe

“…Although these drugs show dramatic effects on a subset of cancer patients, many other tumors are non-responsive and the pathological mechanism of the resistance is largely unknown. …”
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Long COVID in patients with rheumatologic disease: A single center observational study by Horacio Quinones-Moya, Armando Ocampo-Del Valle, Adolfo Camargo-Coronel, Francisco Javier Jimenez-Balderas, Miriam Berenice Bernal-Enriquez, Pedro Madinabeitia-Rodríguez, Kenia Nahomi Morales-Medino, Cynthia Roque-Ibanez, Mario Raúl Hernandez-Zavala

“…The prevalence of fatigue was significantly lower in SLE compared to RA and the rest of the pathologies, but there were no other significant differences between them. …”
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The effect of Garcinia livingstonei aqueous leaf extract on hyperglycaemic-induced human sperm cell: An in-vitro study by Murendeni Nethengwe, Kunle Okaiyeto, Chinyerum S. Opuwari, Oluwafemi O. Oguntibeju

“…However, the use of an appropriate dosage depending on the pathological target is paramount.…”
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Clinical-surgical characterization of patients with acute pancreatitis. Cienfuegos, 2018- 2020 by Jorge Luis Estepa Ramos, Tahiluma Santana Pedraza, Jorge Luis Estepa Pérez, Yudis Acea Paredes, Roberto Pérez García

“…In most patients, serum amylase was pathological; Gallstones prevailed as an ultrasound finding; most of the patients presented mild pancreatitis. …”
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JK-1, a useful erythroleukemic cell line model to study a controlled erythroid differentiation from progenitors to terminal erythropoiesis by Sylvain Metral, Sandrine Genetet, Benoît Gamain, Isabelle Mouro-Chanteloup

“…The possibility of obtaining large quantities of JK-1 cells at each stage of differentiation, as shown in this study, as well as the potential to genetically modify these cells, via CrisprCas9, makes their use of considerable interest for studying pathologies occurring during erythropoiesis.…”
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Metabolic Alteration in Hepatocellular Carcinoma: Mechanism of Lipid Accumulation in Well-Differentiated Hepatocellular Carcinoma by Hideo Suzuki, Motoyuki Kohjima, Masatake Tanaka, Takeshi Goya, Shinji Itoh, Tomoharu Yoshizumi, Masaki Mori, Mariko Tsuda, Motoi Takahashi, Miho Kurokawa, Koji Imoto, Shigeki Tashiro, Akifumi Kuwano, Masaki Kato, Seiji Okada, Makoto Nakamuta, Yoshihiro Ogawa

“…Hepatocellular carcinoma (HCC) presents a unique pathological feature in which lipid accumulation is common in well-differentiated HCC and rare in poorly differentiated HCC; however, the underlying mechanism remains unclear. …”
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Pretreatment with G-CSF Could Enhance the Antifibrotic Effect of BM-MSCs on Pulmonary Fibrosis by Feiyan Zhao, Wei Liu, Shaojie Yue, Lei Yang, Qingzhong Hua, Yan Zhou, Haipeng Cheng, Ziqiang Luo, Siyuan Tang

“…The antifibrotic effects of BM-MSCs in mice were tested on day 21 by using pathological examination and collagen content assay. …”
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Cryopreserved Umbilical Cord Mesenchymal Stem Cells Show Comparable Effects to Un-Cryopreserved Cells in Treating Osteoarthritis by Bo Yan, Huixin Chen, Li Yan, Qiang Yuan, Le Guo

“…In vivo, UC-MSCs and C-MSCs exhibited similar cartilage-repairing effects by attenuating pain and alleviating pathological changes in OA rat joints. In vitro, C-CFM and UC-CM promoted the proliferation of chondrocytes, improved the expression of anabolism-related molecules ( Col2 , COL2, and SOX9), and decreased the expression of catabolism-related molecules ( Adamts5 , Mmp13 , Il6 , COL10, and MMP13). …”
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Comprehensive Insight of Neurodegenerative Diseases and The Role of Neurotoxin Agents — Glutamate by Hui-Min Yap, Kwan-Liang Lye, Loh Teng-Hern Tan

“…Glutamate toxicity, which can be caused by excessive intake of monosodium glutamate (MSG), is the major contributor to pathological neuronal cell death. It causes neuronal dysfunction and degeneration in the central nervous system (CNS). …”
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Investigation of the Pulmonary Artery Hypertension Using an Ad Hoc OpenFOAM CFD Solver by Francesco Duronio, Paola Marchetti

“…A detailed comparative analysis highlights the differences between healthy and pathological cases in hemodynamic terms. The outcomes of this work contribute to enlarging the knowledge of the blood flow characteristics in the human pulmonary artery, revealing substantial differences between the two clinical scenarios investigated and highlighting how arterial hypertension drastically changes the blood flow. …”
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Association of retinal sensitivity with gestational hypertension and obesity by Debasmita Nandi, Swati Majumdar, Prosenjit Banerjee

“…Background: Pregnancy-induced hypertensive disorders occur in about 5% to 8% of all pregnant women in the world and are associated with various pathological changes in the retina due to vasospasm which might have long-term effects on other vital organs too. …”
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Comparison of radiological and computed tomography results of elbow joint in dogs by Canan Kondak Yılmaz, Kurtuluş Parlak, Elgin Orçum Uzunlu, Mustafa Yalçın, Mustafa Arıcan

“…<b>Aim:</b> The aim of this study was to evaluate and compare clinical, radiological and computed tomography results in the early diagnosis of elbow dysplasia which might be a major pathological problem in elbow joint in dogs.<p> <b>Materials and Methods:</b> A total of Twelve dogs prone to articulatio cubiti dysplasia were used as a materials. …”
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Upper Extremity Superficial Vein Thromboses Presenting as Acute Neck Pain in a Young and Healthy Male: A Case Report by Kristen L Zosel, Max K Dummar, Benjamin G Adams, Nancy C Henderson, Richard B Westrick

“…While the majority of neck pain in young and healthy individuals is neuromusculoskeletal in nature, screening for red flags is necessary for ruling-out serious medical pathologies. The purpose of this case report is to describe a young and healthy male subject with a primary complaint of acute neck pain with multiple underlying upper extremity superficial vein thromboses (UESVTs)…”
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Comprehensive analysis of publications concerning combinations of immunotherapy and targeted therapies for hepatocellular carcinoma: a bibliometric study by Biling Gan, Lei Wu, Shunan Zhou, Zhihong Chen, Fan Wu, Lianqun Xu, Zhenrong Chen, Honghui Ma, Peijia He, Dan Fang, Ning Shi

“…Early research primarily focused on angiogenesis, dendritic cells, and expression markers, while recent trends have shifted towards phase III trials, adverse reactions, and checkpoint inhibitors, underscoring the field’s dynamic progression.ConclusionFuture research will expand on the pathological mechanisms underlying these therapies and novel interventions and combination strategies. …”
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Is reflux hypersensitivity truly a functional gastrointestinal disorder? A retrospective cross-sectional study. by Yanping Wu, Siyu Liao, Tianyao Qu, Jiaxuan Zhou, Fei Dai, Bin Qin, Xiaoyu Xu, Jun Zhang, Yan Cheng

“…<h4>Conclusions</h4>Clear pathological alterations, which are distinct from those of other FGIDs, are observable in RH. …”
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