Bilateral inguinal hernioplasty in emergency surgery: Is it feasible? Comparative retrospective study using “propensity score matching” by A. Bravo-Salva, F. Ochoa-Segarra, A. M. González-Castillo, M. Juvany-Gómez, C. Téllez-Marques, L. Riba-Combatti, M. Pérez-Guitart, J. A. Pereira-Rodríguez

“…INTRODUCTION: Hernias, particularly groin hernias, are prevalent surgical pathologies worldwide, often necessitating surgery in cases of complications. …”
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Anisodamine ameliorates crystalline silica-exposed pulmonary inflammation and fibrosis via the α7nAChR/JAK2/STAT3 signaling pathway by Meng Liu, Hui Liu, Hong Kang, Juan Wu, Puhua Xing, Xiaorui Ding, Yangyang Wei, Xiaomei Kong

“…Animal experiments demonstrated that ANI significantly reduced alveolar structure damage and the formation of silicosis nodules in affected mice, as confirmed by pathological slides. ANI inhibited the expression of tumor necrosis factor (TNF-α) in bronchoalveolar lavage fluid (BALF) while promoting the secretion of interleukin-4 (IL-4) and interleukin-10 (IL-10). …”
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Magnetic Induction Phase Difference for Cerebral Hemorrhage Detection by Jie Liu, Lian Yan, Huangsen Deng, Mingxin Qin, Mingsheng Chen

“…This sensor could accurately detect three stages in the pathological process. Blood loss of 1 mL meant that the compensatory mechanism of cerebrospinal fluid began to fail, and 1.4 mL of blood loss meant that the compensatory mechanism failed completely. …”
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Study of Zuojin Pill in Treating Chronic Atrophic Gastritis by UPLC-Q-TOF/MS Based on Serum and Urine Metabolomics Combined with Network Pharmacology by Shihua Wu, Xing Chen, Honghong Liu, Ruilin Wang, Jianyu Li, Jianxia Wen, Tao Yang, Ying Wei, Sichen Ren, Shizhang Wei, Manyi Jing, Haotian Li, Min Wang, Houlin Xia, Yanling Zhao

“…ZJP and omeprazole significantly reduce contents of IL-1β, IL-6, IL-10, and iNOS and improve pathological characteristics. Metabolomic results indicated that the therapeutic effects of ZJP were mainly related to ten metabolites, namely, choline, L-threonine, hydroxypyruvic acid, creatine, taurine, succinic acid, cis-aconitic acid, citric acid, succinic acid semialdehyde, and uric acid. …”
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Interleukin-17: Potential Target for Chronic Wounds by Yasmin Hadian, Michelle D. Bagood, Sara E. Dahle, Apra Sood, R. Rivkah Isseroff

“…The published work supports a pathologic role for interleukin-17 family members in chronic wounds, though this needs to be more conclusively proven. …”
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Unveiling Cathepsin B inhibition with repurposed drugs for anticancer and anti-Alzheimer's drug discovery. by Mohammed Alrouji, Sabina Yasmin, Mohammed S Alshammari, Fahad A Alhumaydhi, Sharaf E Sharaf, Moyad Shahwan, Anas Shamsi

“…Apart from AD, CatB is implicated in various physiological and pathological processes, including cancer. Given the critical role of CatB in these diseases, identifying effective inhibitors is of significant therapeutic interest. …”
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Ventricular Depolarization Abnormalities and Their Role in Cardiac Risk Stratification — A Narrative Review by Maarten Blondeel, Tomas Robyns, Rik Willems, Bert Vandenberk

“…Abnormalities in ventricular depolarization may indicate various pathologies and can be present in all leads if the condition is general, or in a subgroup of anatomically contiguous leads if the condition is limited to the corresponding anatomic location of the heart. …”
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D-Psicose intake exacerbates dextran sulfate sodium-induced colitis in mice through alteration in the gut microbiota and dysfunction of mucosal barrier by Xuejiao Zhang, Ang Li, Yuanyifei Wang, Jin Wang, Bowei Zhang, Yan Zhang, Jingmin Liu, Shuo Wang

“…Here, we firstly evaluated the effect of the D-psicose prophylactic intervention on dextran sulfate sodium-induced colitis in C57BL/6 mice. The pathological symptoms, inflammatory cytokines levels, gut microbiota composition, short chain fatty acids (SCFAs) production and colonic barrier integrity were comprehensively evaluated. …”
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Methimazole Inhibits the Expression of GFAP and the Migration of Astrocyte in Scratched Wound Model In Vitro by Lina Zhao, Xianyu Zhang, Chunhai Zhang

“…Here, we found that methimazole could effectively inhibit the GFAP expression in physiological and pathological conditions. Moreover, we scratched primary cultures of cerebral cortical astrocytes with and without methimazole pretreatment and investigated whether methimazole could slow the healing process in these cultures. …”
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Effect of Nasal Obstructive Disorders on Sinonasal Symptoms in Children with Different Levels of Bronchial Asthma Control by T. I. Eliseeva, S. V. Krasilnikova, N. A. Geppe, S. Yu. Babaev, E. V. Tush, O. V. Khaletskaya, D. Yu. Ovsyannikov, I. I. Balabolkin, S. K. Ignatov, N. I. Kubysheva

“…Allergic rhinitis (AR) and allergic rhinosinusitis (ARS) are typical upper airway pathologies (UAP) in children with bronchial asthma (BA) frequently accompanied with nasal obstructive diseases (NOD). …”
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Factors influencing lateral margin diagnosis challenges in Barrett’s esophageal cancer: a bicenter retrospective study in Japan by Ippei Tanaka, Shuhei Unno, Kazuki Yamamoto, Yoshitaka Nawata, Kimihiro Igarashi, Tomoki Matsuda, Dai Hirasawa

“…Multivariate analysis revealed long-segment Barrett’s esophagus (LSBE) as the sole significant risk factor for BEA (odds ratio, 12.17; 95% confidence interval, 2.84–47.6; p=0.001). Regarding pathological analysis, significant differences were observed in the length and width of the foveolar structure between cancerous and surrounding mucosa in the CD group (p=0.03 and p=0.00, respectively); however, no significant difference was observed in the UD group (p=0.53 and p=0.72, respectively). …”
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Influence of cataract surgery in biopsychosocial adaptation in the elderly by Leonor Rosario Diaz Alfonso, Elvira Machado Héctor, Bárbara Suárez Rodríguez, Mariela Julia Curbelo Gómez

“…Most frequent personal pathological records were arthropathies, diabetes mellitus and hypertension. …”
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Vestibular Dysfunction in Euthyroid Children with Hashimoto’s Thyroiditis by Gülcan Seymen, Gözde Günay, Ahmet Adnan Cirik, Reyhan Sürmeli, Mehmet Sürmeli

“…The vHIT seems to be a valuable tool for identifying and screening preclinical vestibular pathologies in this patient group. …”
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Ultra-small curcumin-ruthenium coordination polymer nanodots prevent renal ischemia-reperfusion injury and the progression to chronic kidney disease by Xian Liu, Qin Yu, Hai-Bo Mao, Jing-Bo Hu, Wei-Hua Liu

“…In summary, our findings confirm that Ru/Cur nanodots mitigate the pathological conditions associated with both AKI and its progression to CKD by reducing IR-induced tubular cell injury.…”
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Role of bovine respiratory syncytial virus in etiology of respiratory diseases on milk farms by S. V. Koteneva, A. V. Nefedchenko, T. I. Glotova, A. G. Glotov

“…The agent spreads widely in all the countries with intensive livestock farming and can cause pathologic changes in respiratory system either alone or in combination with other viruses and bacteria. …”
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Introduction : « La Duchesse d’Amalfi, des humeurs baroques à une passion moderne ? » by Gisèle Venet

“…Webster uses his stage to dissect the pathologically perverse and dominating brothers as in a « Barber-Chirurgeon's-hall », with Bosola as the actor and stage-manager of their passions. …”
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Therapeutic Potential of Stem Cells in Follicle Regeneration by Agnieszka Owczarczyk-Saczonek, Magdalena Krajewska-Włodarczyk, Anna Kruszewska, Łukasz Banasiak, Waldemar Placek, Wojciech Maksymowicz, Joanna Wojtkiewicz

“…We know that stem cells can be used to regenerate hair in several therapeutic strategies: reversing the pathological mechanisms which contribute to hair loss, regeneration of complete hair follicles from their parts, and neogenesis of hair follicles from a stem cell culture with isolated cells or tissue engineering. …”
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Clinical case of combined correction of children's psychotraumatic experience and distress in the development of cancer by K. A. Blinova, E. V. Pchelintseva, N. P. Lapochkina

“…The clinical example described in the article illustrates the close pathological relationship of childhood traumatic experience and the occurrence of the disease, and also confirms the presence of a nonspecific psychosomatic disease in the framework of the diathesis-stress model. …”
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Challenges of early renal cancer detection: symptom patterns and incidental diagnosis rate in a multicentre prospective UK cohort of patients presenting with suspected renal cancer by Michelle Wilson, Naveen S Vasudev, Grant D Stewart, Adebanji Adeyoju, Jon Cartledge, Michael Kimuli, Shibendra Datta, Damian Hanbury, David Hrouda, Grenville Oades, Poulam Patel, Naeem Soomro, Mark Sullivan, Jeff Webster, Peter J Selby, Rosamonde E Banks

“…Comprehensive clinico-pathological and outcome data were also collected.Outcomes Type and frequency of reported symptoms, incidental diagnosis rate, metastasis-free survival and cancer-specific survival.Results Of 706 patients recruited between 2011 and 2014, 608 patients with a confirmed RCC formed the primary study population. …”
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A lineage 1 branch porcine reproductive and respiratory syndrome virus live vaccine candidate provides broad cross-protection against HP-like PRRSV in piglets by Chao Li, Jinhao Li, Bangjun Gong, Hu Xu, Zhenyang Guo, Lirun Xiang, Siyu Zhang, Qi Sun, Jing Zhao, Menglin Zhang, Yan-Dong Tang, Chaoliang Leng, Jianan Wu, Qian Wang, Jinmei Peng, Guohui Zhou, Huairan Liu, Tongqing An, Xuehui Cai, Zhi-Jun Tian, Hongliang Zhang

“…Importantly, the piglets immunised with SD-R exhibited notable reductions in pathological damage, especially of decreases in DLF-induced thymic atrophy. …”
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