Difficultés diagnostiques de la tuberculose cérébrale by Chahrazed Benrabah

“…The diagnosis is postoperative, based on the pathological examination. The prognosis depends on the early diagnosis, the site of the lesion and the response to anti-tuberculosis treatment. …”
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AI-Assisted Compressed Sensing Enables Faster Brain MRI for the Elderly: Image Quality and Diagnostic Equivalence with Conventional Imaging by Gu W, Yang C, Wang Y, Hu W, Wu D, Cai S, Hong G, Hu P, Zhang Q, Dai Y

“…Both protocols showed no significant difference in detecting pathological conditions. The 95% CI for the individual equivalence index was below 5% for all variables except enlarged perivascular spaces, indicating the interchangeability of the conventional and ACS protocols in most cases. …”
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Cytotoxicity towards human endothelial cells, induced by neutrophil myeloperoxidase: protection by ceftazidime by M. Mathy-Hartert, G. Deby-Dupont, C. Deby, L. Jadoul, A. Vandenberghe, M. Lamy

“…These antioxidant properties of CAZ may be clinically useful in pathological situations where excessive activation of neutrophils occurs, such as in sepsis.…”
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Research progress of hypoxia-inducible factor-1α and zinc in the mechanism of diabetic kidney disease by Wei Qin, Ping Nie, Xuejun Hui, Fei Chen, Xingbao Hu, Wenjiao Shi, Manyu Luo, Bing Li

“…This article provides a detailed review of the multiple roles of hypoxia-inducible factor-1α in the pathogenesis of diabetic kidney disease, including: regulating angiogenesis, increasing the expression of erythropoietin, modulating oxidative stress through the PI3K/AKT and HIF-1α/HO-1 pathways, promoting inflammatory cell infiltration and the release of inflammatory factors to induce inflammatory responses, facilitating epithelial-mesenchymal transition, pathological angiogenesis, and promoting the release of fibrotic factors, ultimately leading to renal fibrosis. …”
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Feasibility study of focused ultrasound in the treatment of vulvar low-grade squamous intraepithelial lesions with persistent symptoms by Chang Su, Xinglin Liu, Can Wu, Xi Wang, Chengzhi Li

“…Clinical and histological response were assessed to elucidate the efficacy.Results A total of 22 patients completed follow-up and post-treatment pathological biopsies. After treatment, the clinical scores of itching decreased from 2.55 ± 0.51 to 0.77 ± 0.81 (p < 0.05). …”
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A narrative review of the literature on the pediatric orthopedic management of fibrous dysplasia by Elio Paris, Giacomo De Marco, Oscar Vazquez, Christina Steiger, Sana Boudabbous, Romain Dayer, Dimitri Ceroni

“…Surgical treatment remains appropriate when pain is unresponsive to other medical treatments, when a pathological fracture is impending or has happened, when a deformity is worsening or has formed, or when there is a suspicion of malignant transformation. …”
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Quantification of Macular Vascular Density Using Optical Coherence Tomography Angiography and Its Relationship with Retinal Thickness in Myopic Eyes of Young Adults by Shiqi Yang, Minwen Zhou, Bing Lu, Pengfei Zhang, Jingke Zhao, Mei Kang, Ruoshi Wang, Fenghua Wang, Xiaodong Sun

“…In this cross-sectional study, 268 myopic eyes without pathological changes were recruited and divided into three groups: mild myopia (n=81), moderate myopia (n=117), and high myopia (n=70). …”
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Social behavior and spatial orientation in rat strains with genetic predisposition to catatonia (GC) and stereotypes (PM) by V. S. Plekanchuk, O. I. Prokudina, M. A. Ryazanova

“…Rats with genetic catatonia (GC) and pendulum-like movements (PM) of the anterior half of the body have physiological and behavioral changes similar to those observed in schizophrenia and depression in humans and can be considered as incomplete experimental models of these pathologies. The social behavior of the GC and PM rats has not been previously studied, and the cognitive abilities of animals of these strains are also insufficiently studied. …”
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Predictors of Incisional Hernia after Robotic Assisted Radical Prostatectomy by Avinash Chennamsetty, Jason Hafron, Luke Edwards, Scott Pew, Behdod Poushanchi, Jay Hollander, Kim A. Killinger, Mary P. Coffey, Kenneth M. Peters

“…No statistically significant differences were found in preoperative diabetes, smoking, pathological stage, age, intraoperative/postoperative complications, operative time, blood loss, BMI, and drain type between patients with and without incisional hernias. …”
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Fetal Sacrococcygeal Teratoma: A Case Report of a Giant Tumor with an Excellent Outcome by Anna Kornete, Diana Bokucava, Natalija Vedmedovska

“…The tumor measured 190×160×100 mm and weighed 1100 g. Pathological examination confirmed the diagnosis of a mature teratoma (Grade 0), and the resection margins were negative. …”
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Characterization of NGF, trkANGFR, and p75NTR in Retina of Mice Lacking Reelin Glycoprotein by Bijorn Omar Balzamino, Filippo Biamonte, Graziana Esposito, Ramona Marino, Francesca Fanelli, Flavio Keller, Alessandra Micera

“…This first NGF-trkANGFR/ p75NTR characterization suggests that E-reeler might be suitable for exploring Reelin-NGF cross-talk, representing an additional information source in those pathologies characterized by retinal degeneration.…”
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Isovitexin targets SIRT3 to prevent steroid-induced osteonecrosis of the femoral head by modulating mitophagy-mediated ferroptosis by Yinuo Fan, Zhiwen Chen, Haixing Wang, Mengyu Jiang, Hongduo Lu, Yangwenxiang Wei, Yunhao Hu, Liang Mo, Yuhao Liu, Chi Zhou, Wei He, Zhenqiu Chen

“…Strikingly, restoring SIRT3 expression significantly inhibited pathological mitophagy mediated by the BNIP3/NIX pathway. …”
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Infected burn wound healing using Hydroxy-propyl-methyl cellulose gel containing bacteriophages against Pseudomonas aeruginosa and Klebsiella pneumoniae by Meysam Adibi, Kazem Javanmardi, Noor Al-Huda Ali A.H. Saeed, Mohammad Ali Mobasher, Javad Jokar, Abdolmajid Ghasemian, Niloofar Rahimian, Ava Soltani Hekmat

“…Results: Phages appear to be effective in gel forms. Pathologic samples of different groups confirmed therapeutic results of phages. …”
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Exosomes Regulate the Transformation of Cancer Cells in Cancer Stem Cell Homeostasis by Jiasheng Xu, Kaili Liao, Weimin Zhou

“…Exosomes, as extracellular vesicles, participate in physiological and pathological processes by transmitting signaling molecules such as proteins, nucleic acids, and lipids. …”
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PARylation of HMGA1 desensitizes esophageal squamous cell carcinoma to olaparib by Xin‐Yuan Lei, Kai‐Yue He, Qiu‐Tong Li, Lei Zhang, Dan‐Hui Wu, Jing‐Yu Yang, Jin‐Rong Guo, Meng‐Jie Liu, Zi‐Long Zhao, Jun‐Qi Li, Huai Liu, Yuan Zhao, Yu‐Jia Li, Qian‐Hui Sun, Chen‐Guang Wu, Yun‐Fan Wang, Geng‐Sheng Cao, Gang Wang, Yong‐Ping Jian, Zhi‐Xiang Xu

“…Abstract As a chromatin remodelling factor, high mobility group A1 (HMGA1) plays various roles in both physiological and pathological conditions. However, its role in DNA damage response and DNA damage‐based chemotherapy remains largely unexplored. …”
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Transcriptome analysis of liver injury of fatty liver disease induced by ALDH2 deficiency by Ziying Xu, Yagang Gao, Zihui Yu, Rui Zhang, Ruikun Wang, Shang Li, Shuowen Wang, Bing Du, Ziyan Tian, Lijuan Huang, Zanbo Ding, Jing Yuan

“…Abstract Aldehyde dehydrogenase 2 (Aldh2) Glu504Lys mutation, common in East Asians, is linked to various alcohol-related pathologies, notably fatty liver disease. Recent findings suggest that high ethanol-producing Klebsiella pneumoniae(HiAlc Kpn) exacerbates liver injury in non-alcoholic fatty liver disease (NAFLD). …”
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RatDEGdb: a knowledge base of differentially expressed genes in the rat as a model object in biomedical research by I. V. Chadaeva, S. V. Filonov, K. A. Zolotareva, B. M. Khandaev, N. I. Ershov, N. L. Podkolodnyy, R. V. Kozhemyakina, D. A. Rasskazov, A. G. Bogomolov, E. Yu. Kondratyuk, N. V. Klimova, S. G. Shikhevich, M. A.  Ryazanova, L. A. Fedoseeva, О. Е. Redina, О. S. Kozhevnikova, N. A. Stefanova, N. G. Kolosova, A. L. Markel, M. P. Ponomarenko, Yu. D. Oshchepkov

“…RatDEGdb is novel in that, unlike any other biomedical database, it offers the manually curated annotations of DEGs in model rats with the use of independent clinical data on equal changes in the expression of homologous genes revealed in people with pathologies. The rat DEGs put in RatDEGdb were annotated with equal changes in the expression of their human homologs in affected people. …”
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Perinatal Outcome of Fetal Echogenic Bowel: A Single-Center Retrospective Cohort Study by Hidayet Sal, Erhan Huseyin Comert, Yasin Semih Ekici, Turhan Aran

“…Demographic questionnaire and face to face interview were used to obtain data including immune system diseases and respiratory system pathologies in infants. Results: A total of 100 fetuses with echogenic bowel were included in the study. …”
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Numerical characterization of hemodynamics conditions near aortic valve after implantation of left ventricular assist device by Annalisa Quaini, Sunčica Čanić, David Paniagua

“…The use of LVADs has been associated with thrombus formation next to the aortic valve and close to the anastomosis region,especially in patients in which the native cardiac function isnegligible and the aortic valve remains closed.Stagnation points and recirculation zones have been implicated as the main fluid dynamics factors contributing to thrombus formation.The purpose of the present study was to develop and use computer simulations based on afluid-structure interaction (FSI) solver to study flow conditions corresponding to different strategies inLVAD ascending aortic anastomosis providing a scenario with the lowest likelihood of thrombus formation.A novel FSI algorithm was developed to dealwith the presence of multiple structures corresponding to different elastic properties ofthe native aorta and of the LVAD cannula.A sensitivity analysis of different variables was performed to assess their impact of flow conditionspotentially leading to thrombus formation.It was found that the location of the anastomosis closest to the aortic valve(within 4 cm away from the valve)and at the angle of 30$^\circ$ minimizes the likelihood of thrombus formation.Furthermore, it was shownthat the rigidity of the dacron anastomosis cannula plays almost no role in generating pathologicalconditions downstream from the anastomosis.Additionally, the flow analysis presented in this manuscriptindicates that compliance of the cardiovascular tissue acts as a natural inhibitor of pathological flow conditions conducive to thrombus formationand should not be neglected in computer simulations.…”
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Clinical characteristics of pediatric patients with SARS-CoV-2 infection. Cienfuegos, 2020-2021 by Mercedes Fonseca Hernández, Dunia María Chávez Amaro, Vivian Isabel Chávez Pérez, Julio Héctor Jova Dueñas, Tamara L. Jiménez Sáez, Ifrain Machín Caride

“…The analyzed variables were: age, sex, origin, personal pathological history, initial symptoms, nutritional status, source of infection, laboratory results, persistence of positive RT-PCR, associated clinical manifestations to treatment and evolution. …”
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