Capability of biodentine and the mineral trioxide aggregate mta sealing in furcal perforation repair. Literature review by Silvana Benavides, Alejandra Guallo, Yecenia Carrillo

“…A furcal perforation is a complication that refers to the mechanical or pathological communication between the pulp chamber and supporting ligament, in the lower area of the pulp chamber and leads to the worst result of the treatment. …”
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Preliminary Diagnosis and Characterization of a Spontaneous Immature Testicular Teratoma in an Interferon Receptor-Deficient Mouse Model by ZHAO He, ZHANG Fan, XIAO Yuzhou, AN Xuefang, ZHANG Tao, LI Li

“…The results of HE staining showed that the tumor tissue developed from tissues derived from multiple germ layers, with nerve tissue, bone tissue, muscle tissue, and adipose tissue inside, exhibiting an irregular morphological structure.ConclusionBased on the tumor development, gross morphological structure, and the HE staining results of the pathological sections, the tumor in this mouse was preliminarily diagnosed as an immature teratoma.…”
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Radiation-Associated Fracture Nonunion of the Clavicle Treated with Locking Plate Fixation and Autologous Bone Grafting by Takahiro Niikura, Sang Yang Lee, Yoshitada Sakai, Kotaro Nishida, Ryosuke Kuroda, Masahiro Kurosaka

“…Eight years later, he suffered a pathological fracture of the right clavicle. One year after the fracture, surgical treatment was performed due to persistent pain and weakness. …”
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Gut Microbiota at the Crossroad of Hepatic Oxidative Stress and MASLD by Fabrizio Termite, Sebastiano Archilei, Francesca D’Ambrosio, Lucrezia Petrucci, Nicholas Viceconti, Roberta Iaccarino, Antonio Liguori, Antonio Gasbarrini, Luca Miele

“…This disorder can lead to a range of pathological outcomes, including metabolic dysfunction-associated steatohepatitis (MASH) and cirrhosis. …”
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The Microtubule-Associated Protein Tau and Its Relevance for Pancreatic Beta Cells by Magdalena Maj, Gregor Hoermann, Sazan Rasul, Wolfgang Base, Ludwig Wagner, Johannes Attems

“…We have previously shown that MAPT is present in human islets of Langerhans, human insulinomas, and pancreatic beta-cell line models, with biophysical similarities to the pathological MAPT in the brain. Here, we further studied MAPT in pancreatic endocrine tissue to better understand the mechanisms that lead to functional dysregulation of pancreatic beta cells. …”
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Hyperactivity and Pro-inflammatory Functions of Platelets in Diabetes by Jordan Greaves, Giordano Pula

“…The understanding of the mechanisms underlying the contribution of platelets to cardiovascular pathologies in DM will help the development of targeted therapeutic strategies able to reduce cardiovascular risk in these patients. …”
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Ion‐Permeable Electrospun Scaffolds Enable Controlled In‐Vitro Electrostimulation Assay of Myoblasts by Serafina Pacilio, Francesco Decataldo, Roberta Costa, Tobias Cramer, Beatrice Fraboni, Giovanna Cenacchi, Maria Letizia Focarete

“…This work paves the way for the quantitative study of muscular cell dynamic behavior and physiology, further evaluating therapy effectiveness for muscular pathologies.…”
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Per1/Per2 double knockout transcriptome analysis reveals circadian regulation of hepatic lipid metabolism by Yiran Bu, Si Chen, Mengcheng Ruan, Libang Wu, Hualin Wang, Na Li, Xiuju Zhao, Xiaoli Yu, Zhiguo Liu

“…At the end of the experiment, mice were sacrificed at zeitgeber time (ZT) 0 (7:00 am) or ZT12 (7:00 pm). Pathological indicators were determined using histological and biochemical methods. …”
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Patient Experience and Virtual Reality: The Use of an MRI Exam Simulator by Jaqueline da Silva, Marcus de Souza, Mônica dos Santos, Milena Melo, Lorena Almeida, Alayde Silva, Êmilly Vieira, Alessandra Pontes, Jandson Soares

“…Magnetic resonance (MR) imaging is a safe diagnostic method of high accuracy detection and characterization of various pathological conditions. However, due to the very closed aspect of the apparatus, the high sound amplitude emitted and the need to remain motionless for a significant time, some patients experience discomfort and high levels of anxiety, compromising time and image quality management that can impair the clinical outcome of the patient or even give up the performance of this procedure. …”
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Comparison Of Metacognitions Between Obsessive Compulsive Disorder’s Subtypes And Normal Healthy Controls by Katre DOĞAN, Özgür Saygın SOLAK, Kadir ÖZDEL, Mehmet Hakan TÜRKÇAPAR

“…When it comes to the MCQ-30 scores in autogenous and reactive subtypes of OCD, there was no significant statistical difference between the two groups (p>0.05) Conclusion: Similar metacognitive pathologies in the OCD subtype groups and the difference between OCD and the control group support the thought of using Metacognitive Therapy as a treatment option with no consideration of the subtype. …”
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AKRs confer oligodendrocytes resistance to differentiation-stimulated ferroptosis by Valentina Saverio, Emanuele Ferrario, Romina Monzani, Mara Gagliardi, Francesco Favero, Davide Corà, Claudio Santoro, Marco Corazzari

“…Ferroptosis is a recently characterized form of cell death that has gained attention for its roles in both pathological and physiological contexts. The existence of multiple anti-ferroptotic pathways in both neoplastic and healthy cells, along with the critical regulation of iron metabolism involved in lipid peroxides (lipid-ROS) production—the primary mediators of this cell death process—underscores the necessity of precisely controlling or preventing accidental/unwanted ferroptosis. …”
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Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice by José Belizário, Luiz Vieira-Cordeiro, Sylvia Enns

“…Here we outline the recent discoveries into how the necrotic cell death execution pathway is engaged in many physiological and pathological outcome based on genetic analysis of knockout mice.…”
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Antidiabetic Effect of Young and Old Ethanolic Leaf Extracts of Vernonia amygdalina: A Comparative Study by Du-Bois Asante, Emmanuel Effah-Yeboah, Precious Barnes, Heckel Amoabeng Abban, Elvis Ofori Ameyaw, Johnson Nyarko Boampong, Eric Gyamerah Ofori, Joseph Budu Dadzie

“…Moreover histopathological analysis revealed ameliorative effect of pathological insults induced by the STZ in the pancreas, liver, and spleen, most significantly the regeneration of the beta cells of the islets of Langerhans in treated rats.…”
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Comparison of Scapulohumeral rhythm in individuals with and without Forward Shoulder Posture [version 1; peer review: 1 approved, 2 approved with reservations] by Bhamini Krishna Rao, Divya S, Eliseus Chettiar, Kiransha R. Velingkar, Indu Reddy, Shalini H, Ganesh Balthillaya M, Shyamasunder Bhat N

“…Clinicians, trainers, and sports therapists should be aware of this change to intervene at an early stage and prevent the development of pathological conditions around the shoulder.…”
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WGAN-GP for Synthetic Retinal Image Generation: Enhancing Sensor-Based Medical Imaging for Classification Models by Héctor Anaya-Sánchez, Leopoldo Altamirano-Robles, Raquel Díaz-Hernández, Saúl Zapotecas-Martínez

“…Our approach enhances training datasets by generating realistic retinal images that retain critical pathological features. We evaluated the method across multiple retinal image datasets, including Retinal-Lesions, Fine-Grained Annotated Diabetic Retinopathy (FGADR), Indian Diabetic Retinopathy Image Dataset (IDRiD), and the Kaggle Diabetic Retinopathy dataset. …”
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Advances in Selenium and Related Compounds Inhibiting Multi-Organ Fibrosis by Xiao X, Huang G, Yu X, Tan Y

“…Organ fibrosis, a pathological condition caused by various factors, has become a significant global health issue. …”
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Deficiency of FABP7 Triggers Premature Neural Differentiation in Idiopathic Normocephalic Autism Organoids by Xiao Han, Yuanlin He, Yuanhao Wang, Wenzhu Hu, Chu Chu, Lei Huang, Yuan Hong, Lu Han, Xu Zhang, Yao Gao, Yuan Lin, Hongxia Ma, Hongbing Shen, Xiaoyan Ke, Yan Liu, Zhibin Hu

“…Abstract Autism spectrum disorder (ASD), which is caused by heterogeneous genetic and environmental factors, is characterized by diverse clinical phenotypes linked to distinct pathological mechanisms. ASD individuals with a shared clinical phenotype might contribute to revealing the molecular mechanism underlying ASD progression. …”
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Lipid Oxidation at the Crossroads: Oxidative Stress and Neurodegeneration Explored in <i>Caenorhabditis elegans</i> by Julia Tortajada-Pérez, Andrea del Valle Carranza, Cristina Trujillo-del Río, Mar Collado-Pérez, José María Millán, Gema García-García, Rafael Pascual Vázquez-Manrique

“…In this review, we explore the role of lipid oxidation in protein folding and its associated pathological implications, with a particular focus on findings in neurodegeneration from <i>Caenorhabditis elegans</i> studies, an animal model that remains underutilized. …”
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Visceral Myopathy Presenting as Acute Appendicitis and Ogilvie Syndrome by Punyaram Kharbuja, Raghvendra Thakur, Jian Suo

“…Visceral myopathy is rare pathological condition of gastrointestinal tract with uncertain clinical presentation and unknown etiology. …”
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Hyaluronan Synthase 3 Null Mice Exhibit Decreased Intestinal Inflammation and Tissue Damage in the DSS-Induced Colitis Model by Sean P. Kessler, Dana R. Obery, Carol de la Motte

“…Therefore, we hypothesized that, during a pathologic challenge, HA promotes inflammation. In this study, we tested the progression of inflammation in mice null for the hyaluronan synthase genes (HAS1, HAS3, or both HAS1 and HAS3) in the DSS-colitis model. …”
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