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12041
In Vivo Confocal Microscopy of Cornea in Patients with Terrien’s Marginal Corneal Degeneration
Published 2019-01-01“…Our study demonstrated that the density of corneal epithelial cells, stromal cells, and sensory plexus nerve fibers was significantly reduced in the TMD group. The pathological changes were more obvious in the marginal cornea, and it is correlated with severity of the disease.…”
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12042
Extraintestinal manifestations of inflammatory bowel diseases: arthropathy and arthritis
Published 2018-08-01“…IBDs are diseases with high social impact due to predominance of young patients of working-age and tendency to chronization of pathological process that leads to deterioration of life of patients and high demand in hospital stay. …”
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12043
Pterostilbene antagonizes homocysteine-induced oxidative stress, apoptosis and lipid deposition in vascular endothelial cells
Published 2023-09-01“…Pterostilbene (Pte) has been reported to have antioxidant and anti-apoptotic effects under various pathological conditions. The purpose of this study was to explore whether Pte can inhibit the oxidative stress and apoptosis of vascular endothelium induced by homocysteine (Hcy) and to explain the possible mechanism by which it occurs. …”
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12044
Small cell lung cancer with EML4-ALK fusion: report of a case responding to ALK TKI and literature review
Published 2025-02-01“…Extensive SCLC (cT4N0M1) was diagnosed after relevant examination and pathological examination. The patient relapsed again six months after receiving first-line chemoradiotherapy. …”
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12045
INTENSITY OF NITRIC OXIDE SYNTHESIS IN THE BLOOD OF RATS UNDER THE INFLUENCE OF SODIUM FLUORIDE
Published 2020-12-01“…Oral administration of FN to rats in doses of 1/10 and 1/100 DL50 leads to an increase in the content of nitrite and nitrate anions in the blood plasma during the first 30 days, which indirectly indicates excess production of nitric oxide, which in the initial stages of intoxication may play a compensatory role, but subsequently cause pathological reactions associated with the activation of oxidative stress. …”
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12046
PHILOSOPHIC AND CLINICAL DISCOURSE OF THE TWENTIETH CENTURY
Published 2016-12-01“…Originality of the research lies in definition of the clinical philosophical discourse as a special communicative process, where utterances not only focus on disease syndromes, and reveal phenomenology of inner experience of a pathological self, but also structure a certain type of sociality. …”
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12047
Submandibular Gland Invasion From a Metastatic Lymph Node in Patients With Buccal Mucosal Squamous Cell Carcinoma: A Case Report
Published 2024-01-01“…The tracheostomy, modified radical neck dissection, buccal mucosal cancer resection including maxillary partial resection, mandibular segmentectomy, and reconstructive surgery with a plate and a free rectus abdominis flap were performed. Pathologically, the infiltrating SCC was observed in the SMG continuous with SMLN metastasis (pT4bN3bM0). …”
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12048
MYSM1 attenuates osteoarthritis by recruiting PP2A to deubiquitinate and dephosphorylate RIPK2
Published 2025-01-01“…Abstract Osteoarthritis (OA), the most prevalent degenerative joint disease, is marked by cartilage degradation and pathological alterations in surrounding tissues. Currently, no effective disease-modifying treatments exist. …”
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12049
Evidence of High-Risk Human Papillomavirus in Esophageal Cancer in East Azerbaijan Province, Northwest of Iran
Published 2022-01-01“…Methods. 140 paraffin-embedded specimens of esophageal tissues were investigated using nested-polymerase chain reaction (nested-PCR) with primer designing for the L1 region of HPV genome. According to the pathological diagnosis, the samples were divided into two groups: 70 patients with esophageal cancer EADC (n = 35) and ESCC (n = 35) as the case group and those without tumour in esophagus tissue as a control (n = 70). …”
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12050
The first clinical experience of Marshall’s vein alcohol ablation in complex treatment of persistent atrial fibrillation
Published 2021-03-01“…For example, in persistent AF forms pathological electrical activity often occurs beyond the pulmonary veins. …”
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12051
Application value of 18F-FDG PET/CT in soft tissue metastasis of intrahepatic cholangiocarcinoma: a case report and literature review
Published 2025-01-01“…To further evaluate the presence of other metastases, an 18F-FDG PET/CT scan was performed, which showed abnormal FDG uptake in the liver, peritoneum, left upper femur, right breast, subcutaneous tissues of the thoracic and abdominal regions, and skeletal muscle, while the corresponding CT densities of part of the skeletal muscle and the left upper femur did not show any significant abnormality. Pathologic confirmation of ICC with multiple metastases was obtained by puncture biopsy of the liver and subcutaneous nodes. …”
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12052
Potential Azo-8-hydroxyquinoline derivatives as multi-target lead candidates for Alzheimer's disease: An in-depth in silico study of monoamine oxidase and cholinesterase inhibitors...
Published 2025-01-01“…Cognitive dysfunction in Alzheimer's disease results from a complex interplay of various pathological processes, including the dysregulation of key enzymes such as acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), and monoamine oxidase B (MAO-B). …”
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12053
Changes in the Intestinal Microbiota in Patients with Chronic Pancreatitis: Systematizing Literature Data
Published 2022-12-01“…The human intestinal microbiota is a dynamically changing system that is constantly undergoing qualitative and quantitative changes, especially in several pathological conditions of the digestive system. At present, the differences in the intestinal microbiota in pancreatic diseases are poorly understood. …”
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12054
Role of physical activity in cardiovascular disease prevention: impact of epigenetic modifications
Published 2025-01-01“…Indeed, moderate exercise is not only beneficial to the heart in healthy populations, but also exerts a protective effect in pathological states. However, the molecular mechanisms underlying the cardioprotective effects of exercise are still not fully understood. …”
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12055
Lifestyles characterization in hypertensive patients of the doctor´s office 7 area IV. Cienfuegos, 2021
Published 2022-12-01“…The variables age, skin color, marital status, schooling, personal and family pathological history, eating habits and toxic habits were analyzed.…”
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12056
Mechanism and Therapeutic Prospect of miRNAs in Neurodegenerative Diseases
Published 2023-01-01“…They can inhibit translation or overexpression by combining with mRNA and participate in posttranscriptional regulation of genes, resulting in reduced expression of target proteins, affecting the development, growth, aging, metabolism, and other physiological and pathological processes of animals and plants. It is a powerful negative regulator of gene expression. …”
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12057
Infant of a diabetic mother: clinical presentation, diagnosis and treatment
Published 2024-04-01“…This article presents current knowledge about pathological conditions and the recommended management for IDMs.…”
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12058
Ethnomedical Knowledge of Plants Used in Nonconventional Medicine for Wound Healing in Lubumbashi, Haut-Katanga Province, DR Congo
Published 2024-01-01“…They are indicated in 70 other pathologies. From these 166 taxa, 198 healing recipes are obtained, 11 combining more than one plant. …”
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12059
Therapeutic Adherence and Subjective Well-being in Patients with Type II Diabetes Mellitus
Published 2019-09-01“…<strong><br />Conclusions:</strong> the subjective well-being can be a protective factor for the individual´s health before pathological processes, however, it is not necessarily equivalent to present therapeutic adherence, since in the studied patients, despite having a high subjective well-being, difficulties remained in therapeutic adherence.…”
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12060
Rotavirus in Calves and Its Zoonotic Importance
Published 2021-01-01“…However, various facets of diarrheal disease caused by rotavirus in calves in the world are inadequately understood, considering that diarrheal disease caused by rotavirus is a vital health problem in calves that interrupts production benefits with reduced weight gain and increased mortality, and its potential for zoonotic spread. The pathological changes made by rotavirus are almost exclusively limited to the small intestine that leads to diarrhea. …”
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