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  1. 12041

    In Vivo Confocal Microscopy of Cornea in Patients with Terrien’s Marginal Corneal Degeneration by Ting Chen, Qiangxiang Li, Xiangbo Tang, Min Liao, Hua Wang

    Published 2019-01-01
    “…Our study demonstrated that the density of corneal epithelial cells, stromal cells, and sensory plexus nerve fibers was significantly reduced in the TMD group. The pathological changes were more obvious in the marginal cornea, and it is correlated with severity of the disease.…”
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  2. 12042

    Extraintestinal manifestations of inflammatory bowel diseases: arthropathy and arthritis by Gulustan Hamid Sadygova

    Published 2018-08-01
    “…IBDs are diseases with high social impact due to predominance of young patients of working-age and tendency to chronization of pathological process that leads to deterioration of life of patients and high demand in hospital stay. …”
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  3. 12043

    Pterostilbene antagonizes homocysteine-induced oxidative stress, apoptosis and lipid deposition in vascular endothelial cells by Qiao Jiang, Li Wang, Xu Si, Yuanyuan Bian, Weijia Zhang, Huijun Cui, Hailong Gui, Ye Zhang, Bin Li, Dehong Tan

    Published 2023-09-01
    “…Pterostilbene (Pte) has been reported to have antioxidant and anti-apoptotic effects under various pathological conditions. The purpose of this study was to explore whether Pte can inhibit the oxidative stress and apoptosis of vascular endothelium induced by homocysteine (Hcy) and to explain the possible mechanism by which it occurs. …”
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  4. 12044

    Small cell lung cancer with EML4-ALK fusion: report of a case responding to ALK TKI and literature review by Mingyue Wang, Hongzhi Liu, Ruixin Zhang, Runyu Li, Xiaoyu Qin, Fangling Ning, Lijun Tian

    Published 2025-02-01
    “…Extensive SCLC (cT4N0M1) was diagnosed after relevant examination and pathological examination. The patient relapsed again six months after receiving first-line chemoradiotherapy. …”
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  5. 12045

    INTENSITY OF NITRIC OXIDE SYNTHESIS IN THE BLOOD OF RATS UNDER THE INFLUENCE OF SODIUM FLUORIDE by I.L. Kolisnyk

    Published 2020-12-01
    “…Oral administration of FN to rats in doses of 1/10 and 1/100 DL50 leads to an increase in the content of nitrite and nitrate anions in the blood plasma during the first 30 days, which indirectly indicates excess production of nitric oxide, which in the initial stages of intoxication may play a compensatory role, but subsequently cause pathological reactions associated with the activation of oxidative stress. …”
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  6. 12046

    PHILOSOPHIC AND CLINICAL DISCOURSE OF THE TWENTIETH CENTURY by V. M. Skyrtach, R. S. Martynov, A. O. Karpenko

    Published 2016-12-01
    “…Originality of the research lies in definition of the clinical philosophical discourse as a special communicative process, where utterances not only focus on disease syndromes, and reveal phenomenology of inner experience of a pathological self, but also structure a certain type of sociality. …”
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  7. 12047

    Submandibular Gland Invasion From a Metastatic Lymph Node in Patients With Buccal Mucosal Squamous Cell Carcinoma: A Case Report by Moeka Bukawa, Kenji Yamagata, Satoshi Fukuzawa, Shohei Takaoka, Fumihiko Uchida, Naomi Ishibashi-Kanno, Hiroki Bukawa

    Published 2024-01-01
    “…The tracheostomy, modified radical neck dissection, buccal mucosal cancer resection including maxillary partial resection, mandibular segmentectomy, and reconstructive surgery with a plate and a free rectus abdominis flap were performed. Pathologically, the infiltrating SCC was observed in the SMG continuous with SMLN metastasis (pT4bN3bM0). …”
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  8. 12048

    MYSM1 attenuates osteoarthritis by recruiting PP2A to deubiquitinate and dephosphorylate RIPK2 by Kang Wei, Chuankun Zhou, Zixing Shu, Xingru Shang, Yi Zou, Wei Zhou, Huanhuan Xu, Yulin Liang, Tian Ma, Xuying Sun, Jun Xiao

    Published 2025-01-01
    “…Abstract Osteoarthritis (OA), the most prevalent degenerative joint disease, is marked by cartilage degradation and pathological alterations in surrounding tissues. Currently, no effective disease-modifying treatments exist. …”
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  9. 12049

    Evidence of High-Risk Human Papillomavirus in Esophageal Cancer in East Azerbaijan Province, Northwest of Iran by Zahra Sadeghian, Hossein Bannazadeh Baghi, Vahdat Poortahmasebi, Javid Sadeghi, Alka Hasani, Arezoo Azadi, Mahin Ahangar Oskouee

    Published 2022-01-01
    “…Methods. 140 paraffin-embedded specimens of esophageal tissues were investigated using nested-polymerase chain reaction (nested-PCR) with primer designing for the L1 region of HPV genome. According to the pathological diagnosis, the samples were divided into two groups: 70 patients with esophageal cancer EADC (n = 35) and ESCC (n = 35) as the case group and those without tumour in esophagus tissue as a control (n = 70). …”
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  10. 12050

    The first clinical experience of Marshall’s vein alcohol ablation in complex treatment of persistent atrial fibrillation by V.V. Boiko, S.V. Rybchynskyi, D.O. Lopin, A.S. Vnukova, D.Ye. Volkov

    Published 2021-03-01
    “…For example, in persistent AF forms pathological electrical activity often occurs beyond the pulmonary veins. …”
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  11. 12051

    Application value of 18F-FDG PET/CT in soft tissue metastasis of intrahepatic cholangiocarcinoma: a case report and literature review by Siwen Liu, Xiaohui Sun, Yu Liu, Ning Shi, Xiaoli Zhang, Yuechao Yu

    Published 2025-01-01
    “…To further evaluate the presence of other metastases, an 18F-FDG PET/CT scan was performed, which showed abnormal FDG uptake in the liver, peritoneum, left upper femur, right breast, subcutaneous tissues of the thoracic and abdominal regions, and skeletal muscle, while the corresponding CT densities of part of the skeletal muscle and the left upper femur did not show any significant abnormality. Pathologic confirmation of ICC with multiple metastases was obtained by puncture biopsy of the liver and subcutaneous nodes. …”
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  12. 12052

    Potential Azo-8-hydroxyquinoline derivatives as multi-target lead candidates for Alzheimer's disease: An in-depth in silico study of monoamine oxidase and cholinesterase inhibitors... by Fatima Zahra Guerguer, Bouchra Rossafi, Oussama Abchir, Yasir S Raouf, Dhabya Bakhit Albalushi, Abdelouahid Samadi, Samir Chtita

    Published 2025-01-01
    “…Cognitive dysfunction in Alzheimer's disease results from a complex interplay of various pathological processes, including the dysregulation of key enzymes such as acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), and monoamine oxidase B (MAO-B). …”
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  13. 12053

    Changes in the Intestinal Microbiota in Patients with Chronic Pancreatitis: Systematizing Literature Data by I. V. Maev, A. I. Levchenko, D. N. Andreev

    Published 2022-12-01
    “…The human intestinal microbiota is a dynamically changing system that is constantly undergoing qualitative and quantitative changes, especially in several pathological conditions of the digestive system. At present, the differences in the intestinal microbiota in pancreatic diseases are poorly understood. …”
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  14. 12054

    Role of physical activity in cardiovascular disease prevention: impact of epigenetic modifications by Yi Sun, Zuoying Peng, Hua Liang

    Published 2025-01-01
    “…Indeed, moderate exercise is not only beneficial to the heart in healthy populations, but also exerts a protective effect in pathological states. However, the molecular mechanisms underlying the cardioprotective effects of exercise are still not fully understood. …”
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  15. 12055

    Lifestyles characterization in hypertensive patients of the doctor´s office 7 area IV. Cienfuegos, 2021 by Lianet Pérez Rodríguez, Grissel Utrera Díaz, Laritza Rodríguez Martínez

    Published 2022-12-01
    “…The variables age, skin color, marital status, schooling, personal and family pathological history, eating habits and toxic habits were analyzed.…”
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  16. 12056

    Mechanism and Therapeutic Prospect of miRNAs in Neurodegenerative Diseases by Ya-Min Ma, Lan Zhao

    Published 2023-01-01
    “…They can inhibit translation or overexpression by combining with mRNA and participate in posttranscriptional regulation of genes, resulting in reduced expression of target proteins, affecting the development, growth, aging, metabolism, and other physiological and pathological processes of animals and plants. It is a powerful negative regulator of gene expression. …”
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  17. 12057

    Infant of a diabetic mother: clinical presentation, diagnosis and treatment by Magdalena Suda-Całus, Katarzyna Dąbrowska, Ewa Gulczyńska

    Published 2024-04-01
    “…This article presents current knowledge about pathological conditions and the recommended management for IDMs.…”
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  18. 12058
  19. 12059

    Therapeutic Adherence and Subjective Well-being in Patients with Type II Diabetes Mellitus by Ahmed José Pomares Avalos, Rocío Jorge González, Yuslemi Alfonso Trujillo, Marian Amanda Vázquez Núñez

    Published 2019-09-01
    “…<strong><br />Conclusions:</strong> the subjective well-being can be a protective factor for the individual´s health before pathological processes, however, it is not necessarily equivalent to present therapeutic adherence, since in the studied patients, despite having a high subjective well-being, difficulties remained in therapeutic adherence.…”
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  20. 12060

    Rotavirus in Calves and Its Zoonotic Importance by Umer Seid Geletu, Munera Ahmednur Usmael, Fufa Dawo Bari

    Published 2021-01-01
    “…However, various facets of diarrheal disease caused by rotavirus in calves in the world are inadequately understood, considering that diarrheal disease caused by rotavirus is a vital health problem in calves that interrupts production benefits with reduced weight gain and increased mortality, and its potential for zoonotic spread. The pathological changes made by rotavirus are almost exclusively limited to the small intestine that leads to diarrhea. …”
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