Single-Lung Transplant Results in Position Dependent Changes in Regional Ventilation: An Observational Case Series Using Electrical Impedance Tomography by Kollengode Ramanathan, Hend Mohammed, Peter Hopkins, Amanda Corley, Lawrence Caruana, Kimble Dunster, Adrian G. Barnett, John F. Fraser

“…Positioning in patients with active unilateral lung pathologies will be implicated. This is the first study demonstrating changes in regional ventilation, associated with changes of position between transplanted and diseased lung.…”
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Sound-Induced Round Window Vibration—Experiment and Numerical Simulations of Energy Transfer Through the Cochlea of the Human Ear by Robert Zablotni, Sylwester Tudruj, Jaroslaw Latalski, Marcin Szymanski, Andrzej Kucharski, Grzegorz Zając, Rafał Rusinek

“…These findings provide new insights into cochlear acoustics and offer a potential tool for evaluating pathological disorders and designing prosthetic devices.…”
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Trimethyltin-Induced Microglial Activation via NADPH Oxidase and MAPKs Pathway in BV-2 Microglial Cells by Da Jung Kim, Yong Sik Kim

“…Microglial activation is one of the prominent pathological features of TMT neurotoxicity. Nevertheless, it remains unclear how microglial activation occurs in TMT intoxication. …”
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Prognostic Value of Melanoma Inhibitory Activity Protein in Localized Cutaneous Malignant Melanoma by Angela Sandru, Eugenia Panaitescu, Silviu Voinea, Madalina Bolovan, Adina Stanciu, Sabin Cinca, Alexandru Blidaru

“…The death risk was 12 times higher in pathological MIA group of patients (P=0.0001). Conclusions. …”
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Amino acid stable carbon isotopes in nail keratin illuminate breastfeeding and weaning practices of mother – infant dyads by Hana Salahuddin, Andrea L. Waters-Rist, Fred J. Longstaffe

“…Additionally, δ 13C values of glycine and glutamate indicate maternal physiological and pathological stress due to catabolic effects such as gluconeogenesis. …”
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Optical Coherence Tomography Angiography in Retinal Vascular Diseases and Choroidal Neovascularization by Rodolfo Mastropasqua, Luca Di Antonio, Silvio Di Staso, Luca Agnifili, Angela Di Gregorio, Marco Ciancaglini, Leonardo Mastropasqua

“…OCT-A provides detailed images of retinal vascular plexuses and quantitative data of pathologic structures. Further studies are warranted to define the role of OCT-A in the assessment of retinovascular diseases, with respect to conventional FA and ICG-A.…”
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Low Infection Rate after Tumor Hip Arthroplasty for Metastatic Bone Disease in a Cohort Treated with Extended Antibiotic Prophylaxis by Werner H. Hettwer, Peter Frederik Horstmann, Thea Bechmann Hovgaard, Tomas Andreas Grum-Scwensen, Michael M. Petersen

“…Our findings suggest that extended postoperative antibiotic prophylaxis may reduce the risk of PJI in patients undergoing tumor resection and endoprosthetic replacement for metastatic bone disease associated impending or de facto pathologic fractures of the proximal femur.…”
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S1P Lyase Regulation of Thymic Egress and Oncogenic Inflammatory Signaling by Ashok Kumar, Jesus Zamora-Pineda, Emilie Degagné, Julie D. Saba

“…SPL regulates lymphocyte trafficking, inflammation and other physiological and pathological processes. For example, SPL located in thymic dendritic cells acts as a metabolic gatekeeper that controls the normal egress of mature T lymphocytes from the thymus into the circulation, whereas SPL deficiency in gut epithelial cells promotes colitis and colitis-associated carcinogenesis (CAC). …”
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Virtopsy: Development and Application in Forensic Practice by Dong-Hua Zou, Yuan-Yuan Liu, Ning-Guo Liu, Yi-Jiu Chen

“…Thus, virtopsy can provide visual and powerful evidence for forensic pathological practice. This article mainly synthesizes the latest literature and reviews the application of virtopsy in forensic trauma identification, mechanical asphyxia, drowning, hypothermia and hyperthermia, disease diagnosis, as well as a new research direction of finite element method applied in trauma investigation.…”
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Diabetic Polyneuropathy in Type 2 Diabetes Mellitus: Inflammation, Oxidative Stress, and Mitochondrial Function by Luis Miguel Román-Pintos, Geannyne Villegas-Rivera, Adolfo Daniel Rodríguez-Carrizalez, Alejandra Guillermina Miranda-Díaz, Ernesto Germán Cardona-Muñoz

“…There are three main alterations involved in the pathologic changes of DPN: inflammation, oxidative stress, and mitochondrial dysfunction. …”
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Xeroderma Pigmentosum with Severe Neurological Manifestations/De Sanctis–Cacchione Syndrome and a Novel XPC Mutation by Esteban Uribe-Bojanini, Sara Hernandez-Quiceno, Alicia María Cock-Rada

“…Several genes have been found to be altered in these pathologies, but we lack more genotype-phenotype correlations in order to make an accurate diagnosis. …”
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Placental alterations and their annexes in fetal deaths. Dr. Gustavo Aldereguía Lima Hospital. 2021–2023 by Niuvys Valera Rodríguez, Caridad Socorro Castro, Javier Martínez Navarro, Lisanka Fumero Roldan, Jorge Enrique Rodríguez León

“…Gustavo Aldereguía Lima Hospital, in Cienfuegos, from 2021 to 2023. 58 placentas and their annexes, received in the Pathological Anatomy Department, were analyzed. Macroscopic and microscopic alterations of the placenta were studied.…”
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Modulation of Second Messenger Signaling in the Brain Through PDE4 and PDE5 Inhibition: Therapeutic Implications for Neurological Disorders by Min Kyu Park, Hyun Wook Yang, Seo Young Woo, Dong Yeon Kim, Dae-Soon Son, Bo Young Choi, Sang Won Suh

“…Pharmacological modulation of these enzymes offers potential to enhance cognitive function and mitigate pathological mechanisms underlying brain injuries, neurodegenerative diseases, and psychiatric disorders. …”
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Gastric Endocrine Cell Carcinoma Coexistent with Adenocarcinoma by Nobuhiro Takeuchi, Nomura Yusuke, Tetsuo Maeda, Kazuyoshi Naba

“…Distal gastrectomy with D2 lymph node dissection and Billroth I reconstruction was performed. Pathological examination of the gross specimen revealed that adenocarcinoma comprised <10% of all cancer cells. …”
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Identification of potent TMPRSS4 inhibitors through structural modeling and molecular dynamics simulations by Ismail Hdoufane, Mehdi Oubahmane, Youssef Habibi, Christelle Delaite, Mohammed M. Alanazi, Driss Cherqaoui

“…Abstract TMPRSS4, a transmembrane serine protease type II, is associated with various pathological illnesses. It has been found to activate SARS-CoV-2, enhance viral infection of human small-intestinal enterocytes and is overexpressed in different types of cancers. …”
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Successful Resection of Isolated Para-Aortic Lymph Node Recurrence from Advanced Sigmoid Colon Cancer following 156 Courses of FOLFIRI Regimen by Kaoru Takeshima, Kazuo Yamafuji, Atsunori Asami, Hideo Baba, Nobuhiko Okamoto, Hidena Takahashi, Chisato Takagi, Kiyoshi Kubochi

“…We report the case of a 63-year-old man who underwent sigmoidectomy for sigmoid colon cancer at our hospital. Pathological examination demonstrated advanced sigmoid colon cancer with metastatic involvement in both of the tested PLNs. …”
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Fourier Transform Infrared Spectroscopic Imaging of Fracture Healing in the Normal Mouse by Hans Gollwitzer, Xu Yang, Lyudmila Spevak, Lyudmila Lukashova, Allina Nocon, Kara Fields, Nancy Pleshko, Hayden William Courtland, Mathias P. Bostrom, Adele L. Boskey

“…These data assert the usefulness of FTIRI for evaluation of fracture healing in the mouse and its potential to evaluate pathologic fracture healing and the effects of therapeutic interventions.…”
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Spastic Paraparesis in Young Men With Spinal Meningioma and Spinal Arteriovenous Malformation: A Case Report by Leonard Christianto Singjie, Ivan Jeremia, Esdras Ardi Pramudita

“…We found motor weakness in the lower extremities (1/1), positive pathological reflexes, and sensibility disorders on physical examination. …”
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Psychometric properties and factor structure of the Persian version of worry questionnaire – Contrast avoidance model by Razieh Javaherirenani, Pantea Ahadianfard, Ahmad Ashouri

“…Background: According to the contrast avoidance (CA) model, avoiding sudden emotional changes can lead to pathological worry. There is no valid tool to measure CA tendencies in Iranian people. …”
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Progress in Pathogenesis of Proteinuria by Aihua Zhang, Songming Huang

“…Proteinuria not only is a sign of kidney damage, but also is involved in the progression of renal diseases as an independent pathologic factor. Clinically, glomerular proteinuria is most commonly observed, which relates to structural and functional anomalies in the glomerular filtration barrier. …”
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