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11881
The Interstitial Lymphatic Peritoneal Mesothelium Axis in Portal Hypertensive Ascites: When in Danger, Go Back to the Sea
Published 2010-01-01“…However, their hypothetical appearance in the cirrhotic patient is considered pathological since ultimately they lead to ascites development. …”
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11882
Immunotherapy for Hepatocellular Carcinoma: Current Advances and Future Expectations
Published 2018-01-01“…Hepatocellular carcinoma is the major pathological type of primary liver cancer. Traditional treatment methods for patients with hepatocellular carcinoma have shown poor efficacy in killing residual cancer cells for a long time. …”
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11883
Cellular and Molecular Mediators of Neuroinflammation in the Pathogenesis of Parkinson’s Disease
Published 2013-01-01“…As the relationship between PD and neuroinflammation is being studied, there is a realization that both cellular and molecular mediators are most likely assisting pathological processes leading to disease progression. …”
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11884
Very Late Onset Obsessive-Compulsive Disorder followed by Parkinson Disease: A Case Report
Published 2025-02-01“…Through meticulous examination and correlation with existing research, our case adds weight to the growing body of evidence suggesting a potential link between these two seemingly disparate pathologies. Conclusions: The present case underscores the urgent need for further investigation into the intricate relationship between OCD and PD. …”
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11885
A Case Report of Acute Esotropia in a Young Woman following Heroin Withdrawal
Published 2015-01-01“…Acute onset esotropia is rare and must be investigated right away to exclude central nervous system pathologies, where no opiates use is reported. Diplopia in the form of acute esotropia may manifest in up to 30% of individuals undergoing heroin withdrawal. …”
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11886
Value of Perfusion CT, Transcranial Doppler Sonography, and Neurological Examination to Detect Delayed Vasospasm after Aneurysmal Subarachnoid Hemorrhage
Published 2012-01-01“…The sensitivity, specificity, positive and negative predictive values of delayed ischemic neurological deterioration (DIND), pathological findings on PCT-maps, and accelerations of the mean flow velocity (MVF) were calculated. …”
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11887
Conformational Dynamics of Mitochondrial Inorganic Pyrophosphatase hPPA2 and Its Changes Caused by Pathogenic Mutations
Published 2025-01-01“…In addition to the wild-type enzyme, four mutant variants of hPPA2 were characterized that correspond to the natural pathogenic variants causing severe mitochondrial dysfunction and cardio pathologies. As a result, we identified the global type of flexible motion that seems to be shared by other dimeric PPases. …”
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11888
Activated Circulating T Follicular Helper Cells Are Associated with Disease Severity in Patients with Psoriasis
Published 2016-01-01“…Circulating T follicular helper (cTfh) cells are known to be involved in numerous immune-mediated diseases, but their pathological role in psoriasis is less fully investigated. …”
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11889
Facial Papulopustular Eruption during the COVID-19 Pandemic in Patients Treated with EGFR Inhibitors
Published 2024-01-01“…During COVID-19 pandemics, the use of surgical masks drastically increased and it had an impact on the face skin microenvironment, favoring the worsening of dermatological pathologies. We reported the relapse of PPR in patients treated with EGFR inhibitors who consistently wore face masks (>6 hours/day). …”
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11890
Dysfunctional Attitudes in Alcohol Dependents: A Comparative Study
Published 2012-07-01“…Objective: Cognitive behavioral theory provides a theoretical framework for understanding the etiology and persistence of pathological drinking, and a conceptual basis for developing clinical techniques to treat the disorder. …”
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11891
Aggressive Odontogenic myxoma: a case report
Published 2022-02-01“…<br /><strong>Case presentation:</strong> a clinical case is reported from white male patient, 25 years old, with no apparent personal pathological history is reported. He went to the body of guard of the Manuel Ascunce Domenech Hospital with an inflammatory process of sudden appearance in the right facial region, to the interrogation he referred asymptomatic, with slight limitation to the oral opening, with difficulty for phonation and swallowing. …”
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11892
Accumulation of Bile in the Gallbladder: Evaluation by means of Serial Dynamic Contrast-Enhanced Magnetic Resonance Cholangiography with Gadolinium Ethoxybenzyl Diethylenetriaminep...
Published 2014-01-01“…MR cholangiography obtained with Gd-EOB-DTPA showed that there may be an association between the biliary accumulation pattern in the gallbladder and the pathological condition.…”
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11893
Induced pluripotent stem cell–related approaches to generate dopaminergic neurons for Parkinson’s disease
Published 2025-11-01“…The progressive loss of dopaminergic neurons in affected patient brains is one of the pathological features of Parkinson’s disease, the second most common human neurodegenerative disease. …”
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11894
BMAL1 ameliorates type 2 diabetes-induced cognitive impairment via AREG upregulation and PI3K/Akt/GSK-3β pathway activation
Published 2025-01-01“…Conversely, BMAL1 overexpression mitigated these Alzheimer-like pathologies. Further investigation revealed that BMAL1 directly activated the transcription of Areg, thereby activating the PI3K/Akt/GSK-3β pathway and ameliorating cognitive dysfunction. …”
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11895
Association between Dental Erosion and Diet in Brazilian Adolescents Aged from 15 to 19: A Population-Based Study
Published 2014-01-01“…Dental erosion is a pathological condition resulting from the irreversible dissolution of the mineralized portion of the teeth, being recognized in modern society as an important cause of loss of tooth structure. …”
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11896
PPARs, Cardiovascular Metabolism, and Function: Near- or Far-from-Equilibrium Pathways
Published 2010-01-01“…Dysfunction of clock genes and PPARγ may lead to hyperphagia, obesity, metabolic syndrome, myocardial infarction and sudden cardiac death, In pathological conditions, regulatory processes of the cardiovascular system may bifurcate towards new states, such as those encountered in hypertension, type 2 diabetes, and heart failure. …”
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11897
Long-Term Safety of Transplanting Human Bone Marrow Stromal Cells into the Extravascular Spaces of the Choroid of Rabbits
Published 2017-01-01“…Spectral domain optical coherence tomography (SD-OCT) and histopathology analysis demonstrated no choroidal hemorrhages, retinal detachment, inflammation, or any untoward pathological reactions in any of transplanted eyes or in the control noninjected contralateral eyes. …”
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11898
Contralateral nodal failures in oropharyngeal cancers after TORS and unilateral neck management: a retrospective study
Published 2021-12-01“…Results Thirty-two patients were included. Pathologic T categories included 66% pT1, 31% pT2 and 3% pT3. …”
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11899
Case report: Guillain-Barré syndrome and possible association with Lyme disease
Published 2019-12-01“…We also discuss a possible connection between the two pathologies. …”
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11900
Decoding vascular aging: implications for atherosclerosis progression and clinical intervention
Published 2024-08-01“…Age-related pathologies, particularly cardiovascular disorders, pose a significant global health concern. …”
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