Apelin Protects Primary Rat Retinal Pericytes from Chemical Hypoxia-Induced Apoptosis by Li Chen, Yong Tao, Jing Feng, Yan Rong Jiang

“…Apelin, as the endogenous ligand of G protein-coupled receptor APJ, participates in a number of physiological and pathological processes. To date, the effect of apelin on pericyte is not clear. …”
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Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction by Andrew C. Hiday, Michael C. Edler, Asma B. Salek, Cameron W. Morris, Morrent Thang, Tyler J. Rentz, Kristie L. Rose, Lisa M. Jones, Anthony J. Baucum

“…Our data determine mechanisms that regulate, and putative consequences of, pathological changes in the association of spinophilin with NF-M that are observed in animal models of PD.…”
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A versatile platform based on matrix metalloproteinase-sensitive peptides for novel diagnostic and therapeutic strategies in arthritis by Mingyang Li, Tao Deng, Quan Chen, Shenghu Jiang, Hang Li, Jiayi Li, Shenglan You, Hui-qi Xie, Bin Shen

“…These applications include early and precise diagnosis of MMP activity via fluorescence probe technologies; acting as nanodrug carriers to enable on-demand drug release triggered by pathological microenvironments; and facilitating cartilage engineering through MMP-mediated degradation, which promotes cell migration, matrix synthesis, and tissue integration. …”
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Machine Learning ECG Classification Using Wavelet Scattering of Feature Extraction by Heyam A. Marzog, Haider. J. Abd

“…The heart’s electrical activity is registered by an electrocardiogram (ECG), which consists of a wealth of pathological data on heart diseases such as arrhythmia. …”
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Uncovering a novel SERPING1 pathogenic variant: insights into the aggregation of C1-INH in hereditary angioedema by Lingxi Jiang, Chao Dai, Suyang Duan, Tingting Wang, Chunbao Xie, Luhan Zhang, Zimeng Ye, Xiumei Ma, Yi Shi

“…This study aims to thoroughly investigate the underlying pathological mechanisms of HAE and identify potential biomarkers that could aid in its prediction and prevention. …”
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Rapid growth of a solitary fibrous tumor of the pleura after slow long-term progression: a case report by Daichi Kakibuchi, Shunta Ishihara, Masanori Shimomura, Satoshi Ikebe, Ryota Dobashi, Kazuki Honda, Masayoshi Inoue

“…The patient was discharged following an uneventful course. The tumor was pathologically diagnosed as an SFT with no malignant findings. …”
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The Relevance and Potential Role of Orbital Fat in Inflammatory Orbital Diseases: Implications for Diagnosis and Treatment by Prince Dadson, Peter Ngum, Luis Eduardo Juarez-Orozco, Michael Ntodie, Piotr Loba

“…Inflammatory orbital disease can affect any or all components of the orbit, often arising from various underlying pathologic conditions, including autoimmune, infectious, and vascular diseases. …”
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Diagnostic Study of Pathogenic Bacterial Isolated from Camel’s Pneumonic lungs Slaughtered in Al-Muthanna Province Abattoir, Iraq Using Vitek2 Compactiological approach and Vitek2... by Hayder M Watban, Nabeel M Al-Maaly

“…A cross-sectional study was undertaken at an abattoir, spanning the period from October 2022 to March 2023, to examine gross pathological disorders and identify bacterial pathogens in the respiratory system (specifically the lungs) of camels (Camelus dromedaries) suspected of having pneumonia. …”
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Correlation between Endometrial Vascular Endothelial Growth Factor Expression and Pregnancy Outcome of Frozen–Thawed Embryo Transfer in Patients with Repeated Implantation Failure... by Rui Jin, Wenye Ma, Dawei Tang, Fang Liu, Gang Bai, Mengmeng Reng

“…Vascular endothelial growth factor (VEGF) is a well-known angiogenic factor that is essential to numerous physiological and pathological processes. VEGF also contributes to embryo implantation by promoting embryo development, enhancing endometrial receptivity (ER), and promoting interactions between the endometrium and developing embryo. …”
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Towards more efficient, more specific, and safer MRI contrast agents: a Portuguese–French collaborative journey by Pinto, Sara Martinho Almeida, Lacerda, Sara, Morfin, Jean-François, Aroso, Rafael Tiago,  Teixeira, Daniela Sofia de Sousa, Garda, Zoltán, Pereira, Maria Miguens,  Geraldes, Carlos Frederico Gusmão Campos, Tóth, Éva

“…For the specific targeting of amyloid peptides implicated in many pathologies such as Alzheimer’s disease and diabetes, they have designed benzothiazole-derivative metal chelates with detection potential in MRI, optical, and nuclear imaging modalities. …”
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Central Sensitization-Based Classification for Temporomandibular Disorders: A Pathogenetic Hypothesis by Annalisa Monaco, Ruggero Cattaneo, Maria Chiara Marci, Davide Pietropaoli, Eleonora Ortu

“…Authors include some forms of TMD among central sensitization syndromes (CSS), a group of pathologies characterized by central morphofunctional alterations. …”
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Microcystic Changes in the Retinal Internal Nuclear Layer Associated with Optic Atrophy: A Prospective Study by Benjamin Wolff, Georges Azar, Vivien Vasseur, José-Alain Sahel, Catherine Vignal, Martine Mauget-Faÿsse

“…This study aimed at assessing the prevalence of pathologies presenting retinal inner nuclear layer (RINL) microcystic perimacular changes associated with optic nerve atrophy (OA). …”
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Clinicoradiological Correlation of Macropsia due to Acute Stroke: A Case Report and Review of the Literature by Mayra Johana Montalvo, Muhib Alam Khan

“…Dysmetropsia (macropsia, micropsia, teleopsia, or pelopsia) most commonly results from retinal pathologies, epileptic seizure, neoplastic lesions, viral infection, or psychoactive drugs. …”
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RECQ4-MUS81 interaction contributes to telomere maintenance with implications to Rothmund-Thomson syndrome by Raghib Ashraf, Hana Polasek-Sedlackova, Victoria Marini, Jana Prochazkova, Zdenka Hasanova, Magdalena Zacpalova, Michala Boudova, Lumir Krejci

“…Our findings demonstrate the RECQ4-MUS81 interaction as a key mechanism in alleviating replication stress at hard-to-replicate regions and highlight its relevance in pathological conditions such as RTS.…”
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Large and Small Dendritic Spines Serve Different Interacting Functions in Hippocampal Synaptic Plasticity and Homeostasis by Joshua J. W. Paulin, Peter Haslehurst, Alexander D. Fellows, Wenfei Liu, Joshua D. Jackson, Zelah Joel, Damian M. Cummings, Frances A. Edwards

“…Strong stimuli can also be pathological, causing a homeostatic response, depressing and shrinking the synapse to prevent damage from too much Ca2+ influx. …”
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Humanin Rescues Cultured Rat Cortical Neurons from NMDA-Induced Toxicity Not by NMDA Receptor by Ai-Ling Cui, Jian-Zhong Li, Zhi-Bo Feng, Guo-Lin Ma, Liang Gong, Chun-Ling Li, Ce Zhang, Kefeng Li

“…Excitatory neurotoxicity has been implicated in many pathological situations and there is no effective treatment available. …”
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Oral Squamous Cell Carcinoma: Features and Medico-Legal Implications of Diagnostic Omission by Davide Albano, Antonina Argo, Giuseppa Bilello, Enzo Cumbo, Melania Lupatelli, Pietro Messina, Fabio Massimo Sciarra, Mario Sessa, Stefania Zerbo, Giuseppe Alessandro Scardina

“…Early diagnosis of oncologic pathologies has a crucial role to determine patient’s prognosis and therapeutic path. …”
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Estradiol/testosterone ratio: unveiling links between hormones, sexual function, and health in chronic non-communicable diseases by María A. Gómez-Gutiérrez, Juan M. Huertas-Cañas, Juan M. Montoya-Osorio, Andrés Bedoya-Ossa

“…Materials and methods: This is a case–control study involving 32 adult male patients with chronic pathologies who consulted for sexual dysfunction. Cases defined as subjects with hypoactive sexual desire. …”
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Emerging Role and Therapeutic Implication of Wnt Signaling Pathways in Autoimmune Diseases by Juan Shi, Shuhong Chi, Jing Xue, Jiali Yang, Feng Li, Xiaoming Liu

“…Increasing lines of evidence have suggested a crucial role of Wnt signaling during the pathogenesis of many autoimmune diseases; in addition, some of microRNAs (miRNAs), a class of small, noncoding RNA molecules capable of transcriptionally regulating gene expression, have also recently been demonstrated to possess both physiological and pathological roles in autoimmune diseases by regulating the Wnt signaling pathway. …”
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Antimicrobial Activity of <i>Zingiber Officinale</i> and <i>Allium Sativum</i> on some Drug Resistant Bacterial Isolates by S.E. Emmanuel, E.O. Ehinmitan, R.S. Bodunde, J.C. Joseph

“… Ginger and garlic are very important and useful spices and are used as therapeutic agent against many pathological infections. Increasing multi-drug resistance of pathogens forces researchers to find alternative compounds for treatment of infectious diseases. …”
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