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11701
The Role of Virtual Cystoscopy, after Multidetector Computed Tomography Imaging Reconstruction without the Use of Contrast Medium, in the Diagnosis and Evaluations of Bladder Tumor...
Published 2014-01-01“…Tumor size measured by CT ranged from 3 to 80 mm in diameter. The pathological report revealed noninvasive transitional cell carcinomas in all cases. …”
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11702
Intercellular Mitochondrial transfer: Therapeutic implications for energy metabolism in heart failure
Published 2025-01-01“…Impaired cardiac energy metabolism plays a critical role in the pathological progression of HF. Various forms of HF exhibit marked differences in energy metabolism, particularly in mitochondrial function and substrate utilization. …”
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11703
Overview of hepatocarcinogenesis focusing on cellular origins of liver cancer stem cells: a narrative review
Published 2025-01-01“…Clinically, HCCs exhibit a broad spectrum of pathological and clinical characteristics, ranging from well-differentiated to poorly differentiated forms, and from slow-growing tumors to aggressive ones with significant metastatic potential. …”
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11704
Elastic Modulus of Osteoporotic Mouse Femur Based on Femoral Head Compression Test
Published 2017-01-01“…A biomechanical test is a good evaluation method that describes the structural, functional, and pathological differences in the bones, such as osteoporosis and fracture. …”
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11705
Alpha-Glycerylphosphorylcholine and D-Panthenol Eye Drops in Patients Undergoing Cataract Surgery
Published 2022-01-01“…The surgical procedure is associated with damage to the epithelial barrier and interruption of the corneal innervation. In addition, pathological events sustain signs and symptoms that may persist for a long time. …”
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11706
Sempervirine inhibits proliferation, invasion and metastasis of ovarian cancer cells and induces ultrastructural changes in vivo
Published 2025-01-01“…Furthermore, in an orthotopic ovarian cancer mouse model, sempervirine dramatically inhibited tumor growth and induced pathological changes in tumor tissues, including poor development of tumor mucosa, collagen deposition, endoplasmic reticulum damage, mitochondrial swelling and vacuolar degeneration, which were similar to the positive control 5-Fu. …”
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11707
Novel fusion protein REA induces robust prime protection against tuberculosis in mice
Published 2025-01-01“…Notably, REA-immunized mice suppressed MTB growth to undetectable levels at 16 weeks post-infection, which was supported by gross and pathologic findings and acid-fast staining of the lung tissues, and maintained antigen-specific multifunctional IFN-γ+IL-2+TNF-α CD4+ T and long-lasting T cells producing cytokines in the tissues. …”
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11708
Exploring glycolytic enzymes in disease: potential biomarkers and therapeutic targets in neurodegeneration, cancer and parasitic infections
Published 2025-02-01“…In addition, the potential role of these enzymes as targets for drug development and their potential for use as diagnostic and prognostic markers of some pathologies are also discussed.…”
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11709
ECMO-assisted bilateral uniportal thoracoscopic carinal resection and reconstruction: a case report
Published 2025-01-01“…Abstract Background Carinal resection and reconstruction are complex surgical procedures often necessitated by tumors or other pathologies involving the tracheobronchial junction. …”
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11710
Graph Neural Networks in Brain Connectivity Studies: Methods, Challenges, and Future Directions
Published 2024-12-01“…Findings reveal that GNNs excel in modeling complex, non-linear connectivity patterns and enable the integration of multiple neuroimaging modalities to provide richer insights into both healthy and pathological brain networks. However, challenges remain, particularly in interpretability, data scarcity, and multimodal integration, limiting the full clinical utility of GNNs. …”
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11711
Collagen fibers quantification for liver fibrosis assessment using linear dichroism photoacoustic microscopy
Published 2025-04-01“…Liver fibrosis represents a progressive pathological condition that can culminate in severe hepatic dysfunction, potentially advancing to cirrhosis and liver cancer. …”
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11712
Glioblastoma-derived migrasomes promote migration and invasion by releasing PAK4 and LAMA4
Published 2025-01-01“…We found that expression levels of key migrasome formation factor, tetraspanin 4 (TSPAN4), correlated positively with pathological grade and poor prognosis of GBM based on the databases and clinical samples analysis. …”
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11713
Extracellular Vesicles: A New Prospective in Crosstalk between Microenvironment and Stem Cells in Hematological Malignancies
Published 2018-01-01“…Extracellular vesicles (EVs) are an important cell-to-cell communication type in physiological and pathological conditions. In particular, in HMs, EV secretion participates to unidirectional and bidirectional interactions between neoplastic cells and BM cells. …”
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11714
A 23-Year-Old Female with a Mixed Germ Cell Tumor of the Pituitary Infundibulum: The Challenge of Differentiating Neoplasm from Lymphocytic Infundibuloneurohypophysitis—A Case Repo...
Published 2014-01-01“…The pathologic spectrum of diseases that infiltrate the pituitary infundibulum includes a broad variety of clinical entities. …”
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11715
The Role of the New Anti-CD20 Monoclonal Antibodies in Active Relapsing – Remitting Multiple Sclerosis Treatment: Efficacy and Safety of ofatumumab
Published 2024-03-01“…It is important to control neuroinflammation in the central nervous system caused by the pathologic activity of immune cells by considering a high efficacy treatment early in the disease course in order to prevent accumulation of neurological damage and to improve long term outcomes. …”
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11716
Stromal Vascular Fraction and Amniotic Epithelial Cells: Preclinical and Clinical Relevance in Musculoskeletal Regenerative Medicine
Published 2021-01-01“…The use of SVF and AECs could represent a new regenerative treatment in several musculoskeletal pathologies, solving the problem of cell expansion in vitro.…”
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11717
Uncommon Etiology for Seizure: Cerebral Hyperperfusion Syndrome
Published 2017-01-01“…After bilateral CEA, the imaging showed extensive pathologic process involving primarily the subcortical white matter and overlying cortex, more on the right cerebral hemisphere. …”
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11718
Impact of Time Delay in Perceptual Decision-Making: Neuronal Population Modeling Approach
Published 2017-01-01“…Impairments in decision-making are frequently observed in neurodegenerative diseases, but the mechanisms underlying such pathologies remain elusive. In this work, we study, on the basis of novel time-delayed neuronal population model, if the delay in self-inhibition terms can explain those impairments. …”
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11719
Tissue Factor, Blood Coagulation, and Beyond: An Overview
Published 2011-01-01“…Accordingly, TF suppression, anticoagulation, PAR blockade, or general anti-inflammation offers an array of therapeutical benefits for easing diverse pathological conditions.…”
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11720
Molecular mechanisms in liver repair and regeneration: from physiology to therapeutics
Published 2025-02-01“…An analysis of regenerative variability across pathological states reveals how disease conditions influence these dynamics, guiding the development of novel therapeutic strategies and advanced techniques to enhance liver repair and regeneration. …”
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