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11661
Liposomal Antioxidants for Protection against Oxidant-Induced Damage
Published 2011-01-01“…This paper focus on the use of liposomes for the delivery of antioxidants in the prevention or treatment of pathological conditions related to oxidative stress.…”
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11662
The link between optic neuritis and multiple sclerosis. Literature review
Published 2021-03-01“…Immuno-modulated myelin sheathing and axonal loss causing irreversible neurological dysfunction can be found in both pathologies. Patients who experience these conditions are usually young adults, therefore early diagnosis and control of the disease may benefit in preserving their neurological function and quality of life. …”
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11663
Near-Complete Avipoxvirus Genome Assembled from Skin Lesions of Dead Eurasian Crane (<i>Grus grus</i>)
Published 2024-12-01“…In this study, gross pathological examination and histopathological examination of skin lesions and several organs suggested acute poxvirus infection of a Eurasian crane (<i>Grus grus</i>, Linnaeus, 1758). …”
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11664
Sarcoglycans are enriched at the neuromuscular junction in a nerve-dependent manner
Published 2025-01-01“…Altogether, our findings suggest that pathological decline should no longer be understood only in terms of sarcolemma damage but also in terms of sarcoglycans’ participation in the NMJ. …”
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11665
Inhibition of IAPP Aggregation and Toxicity by Natural Products and Derivatives
Published 2016-01-01“…Fibrillar aggregates of human islet amyloid polypeptide, hIAPP, a pathological feature seen in some diabetes patients, are a likely causative agent for pancreatic beta-cell toxicity, leading to a transition from a state of insulin resistance to type II diabetes through the loss of insulin producing beta-cells by hIAPP induced toxicity. …”
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11666
Synthesis and Characterization of Hydrogel-Based Hyaluronic Acid-Chitosan-Allium sativum Extract for Intraperitoneal Antiadhesion Application
Published 2023-01-01“…Peritoneal Adhesion is a severe case that frequently occurs in patients after laparotomy surgery. Adhesions are pathological attachment that usually appears between the omentum, intestine, and abdominal wall. …”
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11667
Organ preservation strategies for rectal cancer treatment: tarts or trap?
Published 2024-09-01“…In recent years, with advancements in neoadjuvant chemoradiotherapy and the implementation of immunotherapy, the pathological complete response (pCR) rate following neoadjuvant therapy for rectal cancer has significantly increased. …”
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11668
Comparison between Conventional Methods and Molecular Diagnosis for Candida albicans and Candida dubliniensis isolated from Cancer Patients Infected with Oral Candidiasis
Published 2024-10-01“…Conclusion: Both types of pathogenic yeasts that were diagnosed in the current study are the important pathological types prevalent in cancer patients, especially in oral cavity infections, and they are similar to a large extent in terms of phenotypic and diagnostic characteristics.…”
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11669
A Rare Malignant Peripheral Nerve Sheath Tumor of the Maxilla Mimicking a Periapical Lesion
Published 2016-01-01“…Surgical approaches to malignant soft tissue tumor vary based on the extent of the disease, age of the patient, and pathological findings. A rare case of intraosseous malignant peripheral nerve sheath tumor is reported in a 16-year-old woman. …”
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11670
Modeling autoregulation of cardiac excitation-Ca-contraction and arrhythmogenic activities in response to mechanical load changes
Published 2025-02-01“…The model also makes non-trivial predictions on the autoregulation of contraction with moderate MCT-Ca2+ gain under a range of physiological load changes, but arrhythmogenic discordant alternans with excessive MCT-Ca2+ gain under pathological overload.…”
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11671
Electromagnetic Fields, Oxidative Stress, and Neurodegeneration
Published 2012-01-01“…Since free radicals are essential for brain physiological processes and pathological degeneration, research focusing on the possible influence of the EMFs-driven oxidative stress is still in progress, especially in the light of recent studies suggesting that EMFs may contribute to the etiology of neurodegenerative disorders. …”
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11672
Bone‐Targeted Fluoropeptide Nanoparticle Inhibits NF‐κB Signaling to Treat Osteosarcoma and Tumor‐Induced Bone Destruction
Published 2025-01-01“…Abstract Osteosarcoma is a malignant bone cancer usually characterized by symptoms of bone loss due to pathologically enhanced osteoclast activity. Activated osteoclasts enhance bone resorption and promote osteosarcoma cell progression by secreting various cytokines. …”
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11673
Emerging roles of extracellular vesicles in oral and maxillofacial areas
Published 2025-02-01“…To date, studies have revealed the different roles of extracellular vesicles in physiological or pathological processes, as well as applications in disease diagnosis, prognosis, and treatment. …”
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11674
Hepatoid adenocarcinoma of the stomach with ideal response to neoadjuvant chemo-immunotherapy: a case report
Published 2025-01-01“…Subsequent radical surgical intervention confirmed significant tumor shrinkage, with no evidence of lymph node metastasis upon pathological examination. This is the first report of chemotherapy combined with sintilimab in the treatment of gastric hepatoid adenocarcinoma, which may provide novel insights into the therapeutic strategy for HAS.…”
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11675
Natural products targeting ubiquitination to combat kidney fibrosis
Published 2025-01-01“…Abstract Background Kidney fibrosis is a crucial component that contributes to end-stage renal disease and is the inevitable last pathological process in many progressive chronic kidney diseases (CKD). …”
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11676
lncRNA-Triggered Macrophage Inflammaging Deteriorates Age-Related Diseases
Published 2019-01-01“…The detailed mechanism warrants further elucidation to obtain pathological evidence of ARDs and potential treatment approaches.…”
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11677
Concept and Design of a 3D Printed Support to Assist Hand Scanning for the Realization of Customized Orthosis
Published 2017-01-01“…However, hand scanning procedure presents differences between healthy subjects and patients affected by pathologies that compromise upper limb functionality. …”
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11678
Exercise and exerkines: Mechanisms and roles in anti-aging and disease prevention
Published 2025-02-01“…Additionally, the integration of exercise-induced exerkines into therapeutic strategies represents a promising approach to mitigating age-related pathologies at the molecular level. As our understanding deepens, it may pave the way for personalized interventions leveraging physical activity to enhance healthspan and improve quality of life.…”
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11679
Insights from the South Sector at Histria. New archaeological and anthropological data
Published 2024-09-01“…In addition to presenting and discussing the graves with their specific attributes such as the arrangement of diverse funerary structures, as well as body orientation and positioning, the skeletal remains were subjected to anthropological analysis for the first time to estimate the sex and age at death of the individuals and assess their health status while recording the documented pathological conditions. By constructing some individual profiles, we sought to briefly focus on detailing the challenges faced by individuals with particular and to offer insights into their lived experiences and difficulties when faced with such diseases. …”
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11680
Genome-Wide Analysis of DNA Methylation in Human Amnion
Published 2013-01-01“…This work provides preliminary evidence that DNA methylation changes in the amnion may be at least partially involved in the physiological process of labor and the etiology of preterm birth and suggests that DNA methylation profiles, in combination with other biological data, may provide valuable insight into the mechanisms underlying normal and pathological pregnancies.…”
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