Evolving perspectives on aortic stenosis: the increasing importance of evaluating the right ventricle before aortic valve intervention by Vitaliy Androshchuk, Omar Chehab, Joshua Wilcox, Benedict McDonaugh, Natalie Montarello, Ronak Rajani, Bernard Prendergast, Tiffany Patterson, Simon Redwood

“…Despite the increasing emphasis on the pathological significance of RV changes in AS, it remains to be established if earlier detection of these changes can improve the timing for intervention. …”
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The Impact of Purinergic System Enzymes on Noncommunicable, Neurological, and Degenerative Diseases by Margarete Dulce Bagatini, Alessandra Antunes dos Santos, Andréia Machado Cardoso, Aline Mânica, Cristina Ruedell Reschke, Fabiano Barbosa Carvalho

“…These diseases strike from children to elderly and are generally characterized by progressive deterioration of cells, eventually leading to tissue or organ degeneration. These pathological conditions can be associated with disturbance in the signaling mediated by nucleotides and nucleosides of adenine, in expression or activity of extracellular ectonucleotidases and in activation of P2X and P2Y receptors. …”
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An Overview of the Role of Innate Lymphoid Cells in Gut Infections and Inflammation by Silvia Sedda, Irene Marafini, Michele M. Figliuzzi, Francesco Pallone, Giovanni Monteleone

“…In this review, we will summarize the present knowledge on the distribution of ILCs in the intestinal mucosa, with particular focus on their role in the control of both infections and effector cytokine response in immune-mediated pathologies.…”
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Comparative Analysis of miRNA Expression Profiles of Yak Milk-Derived Exosomes at Different Altitudes by Wenwen Ren, Yongfu La, Xiaoming Ma, Xiaoyun Wu, Xian Guo, Min Chu, Ping Yan, Xianyong Lan, Chunnian Liang

“…Milk-derived exosomes, tiny vesicles containing various biological molecules, play crucial roles in numerous pathological and physiological processes, including cell growth, development, and immune regulation. …”
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Meibomian Glands or Not? Identification of In Vivo and Ex Vivo Confocal Microscopy Features and Histological Correlates in the Eyelid Margin by Yu-jing Wang, Min Ke

“…For the diagnostics of pathological eyelid margin lesions, the knowledge of the normal eyelid margin is essential. …”
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Shared signaling pathways and comprehensive therapeutic approaches among diabetes complications by Moein Ebrahimi, Hamid Ahmadieh, Mozhgan Rezaei Kanavi, Sare Safi, Saeed Alipour-Parsa, Soroor Advani, Christine M. Sorenson, Nader Sheibani

“…This review explores the current understanding of shared pathological signaling mechanisms among DM complications and recognizes new concepts that will benefit from further investigation in both basic and clinical settings. …”
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HLA-G Dimers in the Prolongation of Kidney Allograft Survival by Maureen Ezeakile, Vera Portik-Dobos, Juan Wu, Daniel D. Horuzsko, Rajan Kapoor, Muralidharan Jagadeesan, Laura L. Mulloy, Anatolij Horuzsko

“…Limited data are available on the role of soluble HLA-G dimers in clinical pathological conditions. We describe here the presence of soluble HLA-G dimers in kidney transplant patients. …”
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Sodium butyrate attenuate hyperglycemia-induced inflammatory response and renal injury in diabetic mice by Yan Man, Zhang Yan-Yan, Xi Yue, Ding Long-Kun, Sun Chang, Qu Li-Juan, Qian Xin, Xu Jing-Wen, Sun Wen, Wu Liang

“…NaB could alleviate these pathological lesions, but NaB cannot alleviate pancreatic injury. …”
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Working Together and Being Physically Active Are Not Enough to Advise Uniformly and Adequately Low Back Pain Patients: A Cross-Sectional Study by C. Praz, J. Ducki, M. L. Connaissa, P. Terrier, P. Vuistiner, B. Léger, F. Luthi

“…Three clinical vignettes were presented to a group of experts of low back pain (LBP) (guidelines), and 20 physicians, 22 physiotherapists, and 23 nurses to assess how they evaluate the symptoms and pathologies of LBP patients and how much work and physical activity they recommend. …”
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The Neurometabolic Function of the Dopamine–Aminotransferase System by Sergey A. Apryatin

“…An important part of the mentioned pathological conditions are associated with disturbances in protein metabolism, some of the most important biomarkers which are aminotransferases and transcription factors that regulate and direct the most important metabolic reactions. …”
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A Cellular Potts model simulating cell migration on and in matrix environments by Marco Scianna, Luigi Preziosi, Katarina Wolf

“…Cell migration on and through extracellular matrix is fundamental ina wide variety of physiological and pathological phenomena, and isexploited in scaffold-based tissue engineering. …”
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Nanomédicaments pour le traitement de maladies graves et recherches duales by Couvreur, Patrick

“…By releasing the active ingredient at the level of pathological cells and tissues, these nanocarriers help reduce toxicity while improving therapeutic efficacy. …”
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Bifidobacterium breve BB05 alleviates depressive symptoms in mice via the AKT/mTOR pathway by Yanni Pan, Qingling Huang, Yuan Liang, Yuwuqi Xie, Fang Tan, Xingyao Long

“…BB05 treatment also reduced pathological ileal damage, alleviated inflammation, and lowered serum levels of pro-inflammatory cytokines IL-6 and TNF-α. …”
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Pharmacologic Targets and Prototype Therapeutics in the Kallikrein-Kinin System: Bradykinin Receptor Agonists or Antagonists by J. N. Sharma, G.J. AL-Sherif

“…It is a proinflammatory polypeptide that is involved in many pathological conditions and can cause pain, inflammation, increased vascular permeability, vasodilation, contraction of various smooth muscles, as well as cell proliferation. …”
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Impact of surgery on visual acuity and life quality of senile patients by Mariela Julia Curbelo Gómez, Maria Adela Llull Tombo

“…<strong><br />Methods:</strong> A prospective, descriptive, study including variables as age, gender, general and visual personal pathological history of all the patients who attended to the provisional consultation of the General Hospital “Dr. …”
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A Current Review of the Meniscus Imaging: Proposition of a Useful Tool for Its Radiologic Analysis by Nicolas Lefevre, Jean Francois Naouri, Serge Herman, Antoine Gerometta, Shahnaz Klouche, Yoann Bohu

“…Ultrasound is rarely used as a diagnostic tool for meniscal pathologies and its accuracy is operator-dependent. …”
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Understanding the Role of Exercise in Nonalcoholic Fatty Liver Disease: ERS-Linked Molecular Pathways by Yong Zou, Zhengtang Qi

“…Recent studies showed that endoplasmic reticulum stress (ERS) at the subcellular level underlies these featured pathologies in the development of NAFLD. As an effective treatment, exercise significantly reduces hepatic lipid accumulation and thus alleviates NAFLD. …”
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Prepuce: Phimosis, Paraphimosis, and Circumcision by Yutaro Hayashi, Yoshiyuki Kojima, Kentaro Mizuno, Kenjiro Kohri

“…Balanitisxeroticaobliterans is an infiltrative skin condition that causes a pathological phimosis and has been considered to be the only absolute indication for circumcision. …”
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Prenatal maternal stress in rats alters the epigenetic and transcriptomic landscape of the maternal-fetal interface across four generations by Stephanie E. King, Nicola A. Schatz, Olena Babenko, Yaroslav Ilnytskyy, Igor Kovalchuk, Gerlinde A. S. Metz

“…The highly correlated placenta-brain profiles support the use of placenta as a noninvasive biomarker resource to predict pathological changes in the neonatal brain. The transgenerational persistence of critical DNAm, miRNA and mRNA signatures may explain familial non-genetic disease risks.…”
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Is It Necessary to Specifically Define the Cause of Surgically Treated Biliary Tract Infections? A Rare Case of Raoultella planticola Cholecystitis and Literature Review by Suat Can Ulukent, İnanc Samil Sarici, Nuri Alper Sahbaz, Yigit Mehmet Ozgun, Ozlem Akca, Kamuran Sanlı

“…Patient received intravenous antibiotic treatment, but the treatment failed and the patient underwent an open cholecystectomy. The final pathological result was gangrenous cholecystitis complicated with R. planticola. …”
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