Multiple Gastric Erosion Early after a 3 V Lithium Battery (CR2025) Ingestion in an 18-Month-Old Male Patient: Consideration about the Proper Time of Intervention by Ioannis Patoulias, Christos Kaselas, Dimitrios Patoulias, Konstantinos Farmakis, Eleni Papacrivou, Maria Kalogirou, Thomas Feidantsis

“…He did not have any symptoms and no pathological findings were encountered during clinical examination. …”
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Lumbar intervertebral disc calcification with massive herniation: a case report by Junxin Chen, Kangmao Huang, Song Dai, Yuanhang Chen, Wenbin Xu, Xiangqian Fang

“…Intraoperatively, a cystic intraspinal mass with calcification was observed, and upon incision, a toothpaste-like substance flowed out. Pathological examination revealed fibrous tissue with glassy deposits and calcifications. …”
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The role of the extracellular matrix in cardiac regeneration by Xiying Wang, Shuo Yu, Lan Xie, Meixiang Xiang, Hong Ma

“…Moreover, the ECM facilitates the replacement of dead cells and preserves the structural integrity of the heart, making it essential in conditions such as myocardial infarction and other pathological states. When excessive ECM deposition or abnormal production of ECM components occurs, the heart undergoes fibrosis, leading to cardiac dysfunction and heart failure. …”
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Periodontal Care as a Fundamental Step for an Active and Healthy Ageing by Carlo Cafiero, Marco Matarasso, Gaetano Marenzi, Vincenzo Iorio Siciliano, Loredana Bellia, Gilberto Sammartino

“…Diabetes mellitus, obesity, and osteoporosis are very frequent pathological situations in older age. They have been identified as cofactors in the progression of periodontitis. …”
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Ofatumumab successfully treats myelin oligodendrocyte glycoprotein antibody-associated disease accompanied by Epstein-Barr viral infection: a case series by Chen Min, Bi Zhuajin, Liu Peidong, Li Ruoyu, Liu Ju, Liu Hongbo

“…These cases provide new insight into the production of MOG-IgG and the possible pathological mechanisms underlying MOGAD. The cases also confirm the association with EBV, a virus that infects human B cells and has been proposed to be a trigger for MOGAD. …”
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Animal-based evidence supports protective activity of bioengineered silver and gold nanomaterials on hepatic and renal function profile parameters by Hamed Barabadi, Hesam Noqani, Maha Soltani, Ayeh Sabbagh Kashani

“…Key findings reveal the effects of these nanoparticles (NPs) on hepatic enzymes—Aspartate aminotransferase (AST), Alanine transaminase (ALT), and Alkaline phosphatase (ALP)—and renal function markers, including urea and creatinine levels, under both healthy and pathological conditions. In diseased animal models, biosynthesized NPs significantly reduced ALT, AST, ALP, urea, and creatinine levels, demonstrating their protective effects. …”
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Mechanism of podophyllotoxin-induced ovarian toxicity via the AMPK/TSC1/mTOR/ULK1 axis in rats on the basis of toxicological evidence chain (TEC) concept by Jingjing Li, Yanzhao Zhang, Mingyue Wei, Junjie He, Huifeng Ma, Zilong Chen, Jiajia Duan, Chuanxin Liu

“…Results: The rats presented different degrees of diarrhoea, body surface bruising, and petechiae, and the serum biochemical results revealed significant changes in the activities of the oxidative stress indicators SOD and MDA and the levels of the inflammatory indicators TNF-α and IL-1β. The pathological results suggested that the rat ovaries were significantly damaged, and the histological results revealed Th17 cell differentiation, necroptosis, Hspa9 expression, and other pathways or targets related to inflammation, necroptosis/apoptosis or autophagy. …”
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Injectable iodine-containing peptide hydrogel for treatment of MRSA infection by Yu Zhang, Haiyan Liu, Weiqi Zhang, Yinghao Ding, Shengyi Zhang, Xiaowan Huang, Jiali Chen, Zhimou Yang, Feng Lin

“…In this study, we report a novel iodine-containing hydrogel (I2@Nap-FFGP) designed for sustained iodine delivery under humid physiological and pathological conditions. I2@Nap-FFGP was fabricated using a self-assembling peptide-based hydrogel containing a proline motif to form a stable iodine complex. …”
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Overview of Cell Death Mechanisms Induced by Rose Bengal Acetate-Photodynamic Therapy by Elisa Panzarini, Valentina Inguscio, Luciana Dini

“…Photodynamic Therapy (PDT) is a non-invasive treatment for different pathologies, cancer included, using three key components: non-toxic light-activated drug (Photosensitizer, PS), visible light, and oxygen. …”
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CXCL14 in prostate cancer: complex interactions in the tumor microenvironment and future prospects by Lei Tang, Xin Chen, Jianquan Hou, Xuedong Wei

“…Abstract CXCL14 is a highly conserved chemokine expressed in various cell types, playing crucial roles in both physiological and pathological processes, including immune regulation and tumorigenesis. …”
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Contribution à l’analyse de la viabilité d’une petite population de gorilles, Gorilla beringei graueri (Hominidae, Primates), par modélisation et simulations de l’écosystème du Mon... by Jean‑Claude Kasolene Kyungu, Jean Mukulire Malekani, Lohandjola Nyamangombe

“…Nous avons également examiné par PCR, 29 échantillons de matières fécales de gorilles dont 13 pour la détermination de la parenté et 16 pour les pathologies. D’une manière générale, les résultats de la présente étude par rapport aux simulations indiquent : 1) qu’en tenant compte du nombre de mises bas, le taux de natalité s’est avéré se situer au niveau de 0.007. …”
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Intranasal delivery of hMSC-derived supernatant for treatment of ischemic stroke by inhibiting the pro-inflammatory polarization of neutrophils by Yixiang Jiang, Ning Wang, Jingyi Liu, Haoran Ren, Wenkang Jiang, Yanting Lei, Xidan Fu, Miao Hao, Xiujuan Lang, Yumei Liu, Xijun Liu, Rui Li, Hulun Li

“…The neuroprotective effects of hMSC-L and hMSC-M were assessed with TTC staining, behavioral tests and pathological staining. Flow cytometry and qPCR evaluated the expression of immune cells and cytokines in the CNS and peripheral immune organs. …”
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Giant Granular Cell Tumor of the Left Thigh, a Rare Case Report and Literature Review by Liu Q, Kong X, Yang J, Zhang D

“…The postoperative pathological diagnosis confirmed giant GCT.Conclusion: We report a case of a benign giant GCT in the left thigh. …”
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Research on the characteristics of 18F-FDG PET/CT in mantle cell lymphoma and the discrimination between cellular morphological variants by REN Yixuan, CHEN Cheng, CAI Mingci, CHEN Jiamin, YANG Xinxin, WANG Chao, LIN Xiaozhu, CHENG Shu, JIANG Xufeng, CHEN Dongxu

“…Objective·To analyze the imaging characteristics and diagnostic value of 18F-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET/CT) in mantle cell lymphoma (MCL) and explore its application to distinguishing between classic and aggressive variants of MCL.Methods·A retrospective analysis was conducted on the 18F-FDG PET/CT images and clinical data of 116 pathologically confirmed, newly diagnosed MCL patients. …”
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Progress in Study of Low-Intensity Pulsed Ultrasound Acting on Inflammation-Related Signaling Pathways in Knee Osteoarthritis by OUYANG Hui, LIN Xingjin, WANG Jinying, SHEN Longbin, WANG Chengdong

“…Knee osteoarthritis (KOA) is a degenerative total joint disease involving pathological changes in the cartilage, synovium, subchondral bone, and periarticular ligaments and muscles of the joint. …”
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Emodin protects against severe acute pancreatitis-associated acute lung injury by activating Nrf2/HO-1/GPX4 signal and inhibiting ferroptosis in vivo and in vitro by Gang Shen, Haiyun Wen, Huijuan Li, Xuetao Zhang, Bowen Lan, Xuanchi Dong, Peng Ge, Yalan Luo, Hailong Chen

“…Results The findings demonstrated that suppressing Nrf2 expression exacerbated the inflammatory response brought on by SAP and the pathological alterations of SAP-ALI. Emodin treatment reversed this pathological change by activating the Nrf2/Heme Oxygenase-1 (HO-1)/glutathione peroxidase 4 (GPX4) signal path. …”
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Proposing a two-stage screening approach to distinguish between transient and enduring postnatal depressive symptoms: A prospective cohort study by Johanne Smith-Nielsen, Ida Egmose, Stephen Matthey, Maria Stougård, Sophie Reijman, Mette Skovgaard Væver

“…This approach significantly improves referral efficiency and minimizes over-pathologization, enhancing clinical practice in perinatal mental health.…”
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Clinical management of bleeding manifestations in a family with the thrombomodulin C1611>A (p.Cys537Stop) mutation by Serge Pierre-Louis, Johalene Rabout, Octavio Labrada, Fatima Radouani, Emeline Chonville, Beatrice Ferrey, Olivier Pierre-Louis, Yesim Dargaud

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Immune‐dysregulation harnessing in myeloid neoplasms by Mohammad Jafar Sharifi, Ling Xu, Nahid Nasiri, Mehnoosh Ashja‐Arvan, Hadis Soleimanzadeh, Mazdak Ganjalikhani‐Hakemi

“…In recent years, researchers have identified several of these pathological interactions. For instance, recent works shows that the secretion of inflammatory cytokines such as tumor necrosis factor‐α (TNF‐α), from bone marrow stromal cells contributes to immune dysregulation and the selective proliferation of JAK2V617F+ clones in myeloproliferative neoplasms. …”
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Aquaporins in oral health and disease: A narrative review by Shailja Chatterjee

“…Discussion: AQPs are important intramembranous transportation channels that play a significant role in both physiological and pathological conditions of the orofacial complex. The present review provides an overview of the pathophysiology involving AQPs that can help scientists to design treatment therapeutics for various disease conditions.…”
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