Gender Differences in Metabolic Disorders and Related Diseases in Spontaneously Diabetic Torii-Leprfa Rats by Takeshi Ohta, Yoshiaki Katsuda, Katsuhiro Miyajima, Tomohiko Sasase, Shuichi Kimura, Bin Tong, Takahisa Yamada

“…Microangiopathies, such as nephropathy, retinopathy, neuropathy, and osteoporosis, were seen in both genders, and pathological grade and progression were more significant in males. …”
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Papillary Muscles of the Left Ventricle: Integrating Electrical and Mechanical Dynamics by Csilla Andrea Eötvös, Teodora Avram, Roxana Daiana Lazar, Iulia Georgiana Zehan, Madalina Patricia Moldovan, Patricia Schiop-Tentea, Giorgia Coseriu, Adriana Sarb, Gabriel Gusetu, Elena Buzdugan, Roxana Chiorescu, Diana Mocan-Hognogi, Sorin Pop, E. Kevin Heist, Dan Blendea

“…The aim of this review is to offer an overview of the anatomy and physiology of the papillary muscles, along with their involvement in cardiovascular pathologies, including arrhythmia development in various conditions and their contribution to secondary mitral regurgitation. …”
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Progressive histological and behavioral deterioration of a novel mouse model of secondary hydrocephalus after subarachnoid hemorrhage by Xuehai Deng, Jianlin Ding, Chang Liu, Zhong Wang, Junchi Wang, Qiyue Duan, Weida Li, Xinlong Chen, Xiaoping Tang, Long Zhao

“…Choroid plexus cerebrospinal fluid (CSF) hypersecretion, obliterative arachnoiditis occluding the arachnoid villi, lymphatic obstruction, subarachnoid fibrosis, and glymphatic system injury are considered the main pathological mechanisms of hydrocephalus after SAH. Although the mechanisms of hydrocephalus after SAH are increasingly being revealed, the clinical prognosis of SAH still has not improved significantly. …”
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Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics by BingBing Li, Cheng Zhang, XiaoJuan Xu, QiQin Shen, ShuNan Luo, JunFeng Hu

“…It reviewed the epidemiology and pathological characteristics of OS, highlighting its highly malignant nature and tendency for pulmonary metastasis, underscoring the importance of identifying new therapeutic targets. …”
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Primary Roles of Branched Chain Amino Acids (BCAAs) and Their Metabolism in Physiology and Metabolic Disorders by Tomoki Bo, Junichi Fujii

“…Leucine, isoleucine, and valine are collectively known as branched chain amino acids (BCAAs) and are often discussed in the same physiological and pathological situations. The two consecutive initial reactions of BCAA catabolism are catalyzed by the common enzymes referred to as branched chain aminotransferase (BCAT) and branched chain α-keto acid dehydrogenase (BCKDH). …”
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Lone Hepatocellular Carcinoma: An Isolated Chest Wall Malignancy by Joseph Allencherril, Sebastian Bruera, Ronan Allencherril, Richard J. Hamill

“…The patient had no history of hepatitis, alcohol abuse, or illicit substance use. Pathological examination and immunohistochemical staining of the chest mass biopsy were consistent with metastatic hepatocellular carcinoma (HCC). …”
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Laparoscopic Resection of Appendiceal Schwannoma by Toru Imagami, Satoru Takayama, Yohei Maeda, Ryohei Matsui, Masaki Sakamoto, Hisanori Kani

“…Ileocecal resection with D3 lymph node dissection was performed. Pathological and immunohistochemical findings confirmed the diagnosis of appendiceal schwannoma. …”
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Epigenetic regulation in coronary artery disease: from mechanisms to emerging therapies by Rui Gao, Rui Gao, Rui Gao, Meilin Liu, Meilin Liu, Meilin Liu, Haoyi Yang, Haoyi Yang, Haoyi Yang, Yuhan Shen, Yuhan Shen, Yuhan Shen, Ni Xia, Ni Xia, Ni Xia

“…This review synthesizes novel epigenetic insights into CAD, addressing the pathological processes, key molecular mechanisms, and potential biomarkers. …”
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Diabetic Macular Edema Pathophysiology: Vasogenic versus Inflammatory by Pedro Romero-Aroca, Marc Baget-Bernaldiz, Alicia Pareja-Rios, Maribel Lopez-Galvez, Raul Navarro-Gil, Raquel Verges

“…Although the vascular endothelial growth factor (VEGF) is known to play a role in the development of DME, the pathological processes leading to the onset of this disease are highly complex and the exact sequence in which they occur is still not completely understood. …”
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Predictors of cardiac conduction disorders in patients after aortic valve replacement by M.M. Zaretskyi, B.M. Todurov, O.M. Grytsay, V.B. Demyanchuk, O.V. Zelenchuk

“…Cardiac arrhythmias that appear after AVR surgery and require permanent pacemaker (PPM) implantation arise in connection with the anatomical features of the aortic valve, its pathological changes, and traumatic intervention during valve defect correction. …”
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Canonical and noncanonical autophagy: involvement in Parkinson’s disease by Maria Sakurai, Tomoki Kuwahara

“…Autophagy is the major degradation process in cells and is involved in a variety of physiological and pathological functions. While macroautophagy, which employs a series of molecular cascades to form ATG8-coated double membrane autophagosomes for degradation, remains the well-known type of canonical autophagy, microautophagy and chaperon-mediated autophagy have also been characterized. …”
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Therapeutic Potential of Stem Cells Strategy for Cardiovascular Diseases by Chang Youn Lee, Ran Kim, Onju Ham, Jihyun Lee, Pilseog Kim, Seokyeon Lee, Sekyung Oh, Hojin Lee, Minyoung Lee, Jongmin Kim, Woochul Chang

“…CVDs are characterized by a broad range of pathological reactions including inflammation, necrosis, hyperplasia, and hypertrophy. …”
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Ginsenoside Ro prevents endothelial injury via promoting Epac1/AMPK- mediated mitochondria protection in early diabetic retinopathy by Jia Liu, Yunqi Zhang, Xiaoyu Xu, Xi Dong, Yunfeng Pan, Xiaobo Sun, Yun Luo

“…Moreover, Ro alleviated DR progress through improving retinal thickness and pathological changes in STZ-induced diabetic mice. Mechanically, Ro promotes the activation of Epac1-mediated AMPK signaling. …”
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Pengaruh Harga Diri dan Kesejahteraan Psikologis terhadap Celebrity Worship pada Dewasa Awal Penggemar K-pop by Nada Nur Zahra, Primatia Yogi Wulandari

“…Hasil penelitian ini menunjukkan bahwa harga diri dan kesejahteraan psikologis secara simultan dan parsial tidak memiliki pengaruh signifikan terhadap celebrity worship intense-personal dan borderline-pathological (sig > 0,05). Dapat disimpulkan bahwa harga diri dan kesejahteraan psikologis tidak berpengaruh terhadap celebrity worship.…”
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Scorpion Venom and the Inflammatory Response by Vera L. Petricevich

“…Victims of envenoming by a scorpion suffer a variety of pathologies, involving mainly both sympathetic and parasympathetic stimulation as well as central manifestations such as irritability, hyperthermia, vomiting, profuse salivation, tremor, and convulsion. …”
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Aspirin inhibits proteasomal degradation and promotes α-synuclein aggregate clearance through K63 ubiquitination by Jing Gao, Yang Liu, Chenfang Si, Rui Guo, Shouqiao Hou, Xiaosong Liu, Houfang Long, Di Liu, Daichao Xu, Zai-Rong Zhang, Cong Liu, Bing Shan, Christoph W. Turck, Kaiwen He, Yaoyang Zhang

“…Accordingly, using the major pathological protein of Parkinson’s disease (PD), α-synuclein (α-syn), as an example of protein aggregates, we find that aspirin is able to reduce α-syn in cultured cells, neurons, and PD model mice with rescued locomotor ability. …”
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Insulin in Central Nervous System: More than Just a Peripheral Hormone by Ana I. Duarte, Paula I. Moreira, Catarina R. Oliveira

“…Herewith, we aim to integrate the metabolic, neuromodulatory, and neuroprotective roles of insulin in two age-related pathologies: diabetes and AD, both in terms of intracellular signaling and potential therapeutic approach.…”
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Manual Removal of the Placenta after Vaginal Delivery: An Unsolved Problem in Obstetrics by Fiona Urner, Roland Zimmermann, Alexander Krafft

“…Despite scant evidence it is commonly advised that if the placenta has not been expelled 30 minutes after delivery, manual removal of the placenta should be carried out under anaesthesia. Pathologic adhesion of the placenta in the low risk situation usually is diagnosed at the time of delivery; therefore a pre- or intrapartum screening opportunity for placenta accreta would be desirable. …”
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Evidence-Based Approach through a Critical Look at Strategic Management Theories by Vahid Khashei Varnamkhasti, Elham Sadat Sabour Abvani

“…This research has been done in the insurance industry and while having a pathological view of strategic decisions that are taken at the head of insurance companies, the researcher has tried to find a model of strategic decision-making based on evidence from the discourses of senior managers of insurance companies. …”
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Lifor Solution: An Alternative Preservation Solution in Small Bowel Transplantation by Mingxiao Guo, Chunlei Lu, Ying Gao, Haifeng Zhang, Dongfeng Chen, Yousheng Li

“…After 9 h cold preservation, pathological changes, the content of ATP in the intestinal mucosa, and the intestinal absorptive function after transplantation in group 2 were similar to those of group 1. …”
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