A Highly Selective Fluorescent Probe for Hypochlorous Acid in Living Cells Based on a Naphthalene Derivative by Jingguo Sun, Junhong Xu, Qiujuan Ma, Guojiang Mao, Nannan Zhu, Meiju Tian, Linke Li, Shuzhen Liu

“…Hypochlorous acid (HOCl) was crucial for maintaining the homeostasis in cells and plays vital roles in many physiological and pathological processes. In this work, a highly selective fluorescent probe for hypochlorous acid in living cells was constructed and prepared based on a naphthalene derivative. …”
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Popliteal Artery Entrapment or Chronic Exertional Compartment Syndrome? by Christopher Gaunder, Brandon McKinney, Jessica Rivera

“…Of these, the least frequent but potentially most serious of the pathologies is PAES. With an incidence of less than 1% seen in living subject studies, the condition is rare. …”
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Controversy About Management of Osteoarthritis with Disease-modifying Anti-rheumatic Drugs by CUI Hanshu, LIU Bin

“…Osteoarthritis (OA) is a degenerative joint cartilage disease characterized pathologically by osteophytes formation and subchondral bone damage. …”
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Le travail … c’est la santé : la santé au travail … une pratique en question by Paul Frimat

“…Numerous reports have been written in the last five years to debate the legitimacy of maintaining such a concept, as well as its efficiency as far as the prevention of work-related pathologies is concerned. A law will certainly be expected at the end of 2009/beginning of 2010. …”
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Eosinophils: old cells, new directions by Alejandra Sanchez Santos, Iovanna Socorro Avila, Helena Galvan Fernandez, Sara Cazorla Rivero, Sara Cazorla Rivero, Angelina Lemes Castellano, Carlos Cabrera Lopez

“…In recent years, various biological therapies targeting these cells have been developed, altering the course of eosinophilic pathologies. Recent research has demonstrated differences in eosinophil subtypes and their functions. …”
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Tropheryma whipplei infection presenting as indolent endophthalmitis by Rami Waked, Jeffrey K. Moore, Brandon Winward, Sophia Ham, Howard W. Hoyt, Leyla Azis

“…Gastrointestinal endoscopic and cerebrospinal fluid studies revealed no pathological or molecular evidence of the disease, complicating the diagnosis. …”
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An Unusual Complication in Plastic Periodontal Surgery by Jorge Vagarinho, Sara Sardinha, Ricardo Alves

“…Oroantral communications may arise as a result of pathological processes or iatrogenic situations, particularly in oral surgery and implantology, but are uncommon in periodontal plastic surgery. …”
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Protective Effects of Polydatin on Septic Lung Injury in Mice via Upregulation of HO-1 by Xiao-hui Li, Xia Gong, Li Zhang, Rong Jiang, Hong-zhong Li, Meng-jiao Wu, Jing-yuan Wan

“…Pretreatment of mice with PD (15, 45, and 100 mg/kg) dose-dependently reduced sepsis-induced mortality and lung injury, as indicated by alleviated lung pathological changes and infiltration of proteins and leukocytes. …”
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Roles of Mesenchymal Stem Cells in Spinal Cord Injury by Jing Qu, Huanxiang Zhang

“…Spinal cord injury (SCI) represents one of the most complicated and heterogeneous pathological processes of central nervous system (CNS) impairments, which is still beyond functional regeneration. …”
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The amplitude of low frequency fluctuation and spontaneous brain activity alterations in age-related macular degeneration by Yan Yan Zhang, Jin Yu Hu, Qian Ling, San Hua Xu, Min Kang, Hong Wei, Jie Zou, Quanyong Yi, Gang Tan, Yi Shao, Yi Shao

“…The amplitude of low-frequency fluctuation (ALFF) method was used to observe changes in spontaneous brain activity, which may help to investigate the underlying pathological mechanism of AMD.MethodsEighteen patients with wAMD and 18 age- and gender-matched healthy controls (HCs) were recruited. …”
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Massive vulval edema with severe preeclampsia. Case report by Nelson Pérez Rumbaut, José Luis Durán Páez, José Luis Gómez Miranda.

“…A very peculiar manifestation of edema on preeclampsia is massive vulval edema, which appears as a highly rare complication, in whose basis there is a complex, systemic pathological process involved. We present a case of a pregnant woman who was admitted with high blood pressure values and excessive weight gain, plus very noticeable general edemas, and during her stay developed massive vulval edema. …”
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The role of esophageal and stomach motility disorders in pathogenesis of gastroesophageal reflux disease by Yu. V. Yevsyutina, A. S. Trukhmanov

“…In patients with GERD disorders of primary and secondary peristalsis of the esophagus, increase of frequency of transient lower esophageal sphincter relaxations and pathologic bile refluxes are common.Conclusion. Numerous studies are devoted to investigation of gastroesophageal reflux disease. …”
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Peroxisome proliferator–activated receptor delta and liver diseases by Tomoo Yamazaki, Edward E. Cable, Bernd Schnabl

“…PPAR-delta not only regulates physiologic processes of lipid, glucose, and bile acid metabolism but also attenuates pathologic responses to alcohol metabolism, inflammation, fibrosis, and carcinogenesis, and is considered an important therapeutic target in liver diseases. …”
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Reidel’s Thyroiditis, a Diagnostic and Management Challenge: A Case Report and Review of the Literature by Yassine Er-Rahali, Mohammed Massine El Hammoumi, Jad Issouani, Colna Antonio Nfad, Souad El Moussaoui, El Hassane Kabiri, Ahmed Anass Guerboub

“…A hard subtotal thyroidectomy was performed. Pathological study confirmed Riedel's thyroiditis with the presence of IgG4 antibodies in immunohistochemistry. …”
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“Isolated” Amelogenesis Imperfecta Associated with DLX3 Mutation: A Clinical Case by Anne-Laure Bonnet, Kevin Sceosole, Arabelle Vanderzwalm, Caroline Silve, Anne-Margaux Collignon, Celine Gaucher

“…This report illustrates the challenge of diagnosing dental structure anomalies, specifically AI, in adults and highlights the need for an accurate and accessible molecular diagnosis for those anomalies to discriminate between isolated and syndromic pathologies.…”
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Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy by Tom Verfaillie, Maria Salazar, Guillermo Velasco, Patrizia Agostinis

“…Different physiological and pathological conditions can perturb protein folding in the endoplasmic reticulum, leading to a condition known as ER stress. …”
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Role of PPARα and Its Agonist in Renal Diseases by Ching-Feng Cheng, Hsi-Hsien Chen, Heng Lin

“…This paper focuses on signaling pathways, ligand selectivity, and physio-pathological roles of PPARα in kidney diseases and the therapeutic utility of PPARα modulators in the treatment of diabetes and inflammation-induced nephropathy. …”
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TNF-α as a Therapeutic Target in Acute Pancreatitis — Lessons from Experimental Models by Giuseppe Malleo, Emanuela Mazzon, Ajith K. Siriwardena, Salvatore Cuzzocrea

“…In particular, it is pivotal in many detrimental effects of acute pancreatitis, and it represents a major determinant of the systemic progression and end-organ damage (such as acute lung injury and liver failure) of this pathologic condition. Given the importance of TNF-α in the pathogenesis of acute pancreatitis, investigators have regarded blocking the action of this mediator as an attractive treatment option. …”
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Effectiveness of low-dose topical atropine in preventing the progression of myopia – A prospective interventional cohort study in pediatric patients by Tara Susan Mohan, Liji Menon, Mary Shimy, Binu Balan, Latha Panicker

“…Background: Myopia is a very common pathological condition in the pediatric age group which can lead to devastating complications if not treated early. …”
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Endometriosis Gene Expression Heterogeneity and Biosignature: A Phylogenetic Analysis by Mones Abu-Asab, Ming Zhang, Dennis Amini, Nihad Abu-Asab, Hakima Amri

“…Our objective was to characterize the heterogeneous pathological process using parsimony phylogenetics. Gene expression microarray data of ovarian endometriosis obtained from NCBI database were polarized and coded into derived (abnormal) and ancestral (normal) states. …”
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