Rat Model of Cystic Neutrophilic Granulomatous Mastitis by Corynebacterium Kroppenstedtii by Wang M, Zeng Y, Liu M, Zhang D, Zhao D, Wang J, Liu Y, Zhao W

“…Rats in group G presented with masses without ulceration, only chronic and acute inflammatory cell infiltration in pathological. Levels of C-reactive protein and interleukin-1 beta were significantly elevated in groups A and E at day 14.Conclusion: Components of pathological tissues from granulomatous mastitis patient combined with CK suspension, can successfully induce CNGM in rat models.Keywords: cystic neutrophilic granulomatous mastitis, Corynebacterium kroppenstedtii, rat model, granulomatous mastitis…”
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Injecting hope: the potential of intratumoral immunotherapy for locally advanced and metastatic cancer by Marketa Skalickova, Marketa Skalickova, Katerina Hadrava Vanova, Ondrej Uher, Jindriska Leischner Fialova, Jindriska Leischner Fialova, Jindriska Leischner Fialova, Katerina Petrlakova, Michal Masarik, Michal Masarik, Michal Masarik, Michal Masarik, Zdeněk Kejík, Zdeněk Kejík, Pavel Martasek, Karel Pacak, Milan Jakubek, Milan Jakubek

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Diagnosis and treatment of hepatocellular carcinoma with pelvic metastasis expressing AFP: a case report by Legang Huang, Zijie Wang, Jiankuan Lu

“…The combination of PET-CT imaging and pathological biopsy is instrumental in improving the detection rate of HCC metastases, enabling more accurate treatment planning for patients.…”
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Multiple Low Energy Long Bone Fractures in the Setting of Rothmund-Thomson Syndrome by Nicholas Beckmann

“…Although Rothmund-Thomson syndrome is associated with diminished bone mineral density in addition to multiple skeletal abnormalities, there are few reports of the association with stress fractures or pathologic fractures in low energy trauma or delayed healing of fractures. …”
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Regional sonology of the upper limb - II: Wrist and hand by Bipin R Shah, Ankit B Shah

“…The flexor tendons and the median nerve along the volar aspect of the wrist pass through a fibro-osseous tunnel known as the carpal tunnel. US pathologies commonly encountered in inflammatory arthritis have been very well defined in literature, so that there is better reproducibility of the tests and reduction in the inter-observer variation.…”
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Metabolomic and lipidomic pathways in aneurysmal subarachnoid hemorrhage by Bosco Seong Kyu Yang, Spiros L. Blackburn, Philip L. Lorenzi, Huimahn A. Choi, Aaron M. Gusdon

“…In particular, metabolomics—the study of small molecules, such as blood products, carbohydrates, amino acids, and lipids—can provide a snapshot of dynamic subcellular processes and thus broaden our understanding of molecular-level pathologic changes that lead to the systemic response after aSAH. …”
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Anti-Amyloid Imaging Abnormality in the Era of Anti-Amyloid Beta Monoclonal Antibodies: Recent Updates for the Radiologist by So Yeong Jeong, Chong Hyun Suh, Jae-Sung Lim, Yangsean Choi, Ho Sung Kim, Sang Joon Kim, Jae-Hong Lee

“…Anti-amyloid immunotherapy has shown potential to modify the progression of the disease by specifically binding to amyloid β, a key pathological product in Alzheimer’s disease, and eliminating accumulated amyloid plaques in the brain. …”
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Unveiling the mystery of hepatic epithelioid angiomyolipoma: A unique case report with literature review by Da Teng, Yue Xu, Qingtao Meng, Qingsong Yang

“…Clinical presentation, laboratory findings, and imaging results lack specificity, making pathological examination critical for definitive diagnosis. …”
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Active Roles of Tumor Stroma in Breast Cancer Metastasis by Zahraa I. Khamis, Ziad J. Sahab, Qing-Xiang Amy Sang

“…A reciprocal dynamic interaction occurs between the tumor cells and their surrounding stroma under physiological and pathological conditions. This tumor-host communication interface mediates the escape of tumor cells at the primary site, survival of circulating cancer cells in the vasculature, and growth of metastatic cancer at secondary site. …”
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A Review of Metal Exposure and Its Effects on Bone Health by Juliana Rodríguez, Patricia Mónica Mandalunis

“…Long term exposure and short exposure to high concentrations induce an imbalance in the bone remodeling process, altering both formation and resorption and leading to the development of different bone pathologies.…”
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Role of copper homeostasis and cuproptosis in heart failure pathogenesis: implications for therapeutic strategies by Zhichao Liu, Yongkang Gan, Zhen Shen, Siqi Cai, Xizhen Wang, Yong Li, Xiaofeng Li, Huanjie Fu, Jinhong Chen, Ningcen Li

“…Consequently, dysregulation of copper homeostasis—either excessive or deficient—can lead to pathological changes, such as heart failure (HF). Recently, a new type of copper-dependent cell death known as cuproptosis has drawn increasing attention to the impact of copper dyshomeostasis on HF. …”
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Tumor Resection, Reconstruction, and Ankle Fusion for Recurrent Giant Cell Tumor of the Distal Tibia by Alok C. Agrawal, Mukund Madhav Ojha, Somok Banerjee

“…A male patient presented to us with pathological fracture of the left distal tibia due to recurrent GCT. …”
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Mitochondrial DNA leakage: underlying mechanisms and therapeutic implications in neurological disorders by Guangming Zhang, Huayuan Wei, Anliu Zhao, Xu Yan, Xiaolu Zhang, Jiali Gan, Maojuan Guo, Jie Wang, Fayan Zhang, Yifang Jiang, Xinxing Liu, Zhen Yang, Xijuan Jiang

“…The escaped mtDNA activates cytosolic DNA sensors, especially cyclic gmp-amp synthase (cGAS) signalling and inflammasome, initiating neuroinflammatory cascades via pathways, exacerbating a spectrum of neurological pathologies. The therapeutic promise of targeting mtDNA leakage is discussed in detail, underscoring the necessity for a multifaceted strategy that encompasses the preservation of mtDNA homeostasis, prevention of membrane leakage, reestablishment of mitochondrial dynamics, and inhibition the activation of cytosolic DNA sensors. …”
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Adult-onset Renal Neuroblastoma: Case Report and Literature Review by Yao-Ren Yang, Cih-En Huang

“…The initial impression was renal cell carcinoma, and a right nephroureterectomy with regional lymph node dissection was performed. Pathologic examination confirmed the diagnosis of primary renal neuroblastoma with a differentiating subtype. …”
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Multispectral Bioluminescence Tomography: Methodology and Simulation by Alexander X. Cong, Ge Wang

“…Bioluminescent imaging has proven to be a valuable tool for monitoring physiological and pathological activities at cellular and molecular levels in living small animals. …”
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Challenges and Prospects of Sensing Technology for the Promotion of Tele-Physiotherapy: A Narrative Review by Kei Kakegawa, Tadamitsu Matsuda

“…The development of these technologies will not only enhance the accuracy of deep learning by AI through the acquisition of big data, but also has the potential to elucidate movement characteristics associated with movement disorders or pathological conditions. Furthermore, improving sensing technologies can broaden applications extending beyond tele-physiotherapy to impact daily life. …”
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Use of Flavonoids and Cinnamates, the Main Photoprotectors with Natural Origin by Alesandra R. Nunes, Ícaro G. P. Vieira, Dinalva B. Queiroz, Antonio Linkoln Alves Borges Leal, Selene Maia Morais, Débora Feitosa Muniz, João Tavares Calixto-Junior, Henrique Douglas Melo Coutinho

“…Many pathological problems are initiated by ultraviolet radiation (UVR), such as skin cancer, the most commonly diagnosed cancer worldwide. …”
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The Relationship between Osteoporosis and Osteoarthritis of the Knee: A Report of 2 Cases with Suspected Osteonecrosis by Akira Horikawa, Naohisa Miyakoshi, Yoichi Shimada, Hiroyuki Kodama

“…In both patients, preoperative bone mineral densities of the femoral condyle and proximal tibia of the affected side were lower than those of the unaffected side. Pathological examination of the resected femoral condyle and proximal tibia showed almost intact joint cartilage, healing of the collapsed subchondral bone, and significant trabecular bone loss. …”
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Could flavonoid aglycones prevent the absorption of flavonoid glycosides by inhibiting sodium-dependent glucose transporter-1 in the small intestine? by Katrin Sak

“…Flavonoids present a large group of natural polyphenols with numerous important health benefits for preventing and treating a diverse variety of pathological conditions. However, the actual therapeutic use of these phytochemicals is impeded by their low oral bioavailability. …”
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Pulmonary Blastoma: A Rare Primary Lung Malignancy by Mahmoud S. Alahwal, Iqbal H. Maniyar, Faiza Saleem, Mariam Alshiekh

“…Pulmonary blastoma, a rare primary lung malignancy, is considered to be distinct from other lung tumors based on pathological features, clinical course, and prognosis. …”
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