Identified VCAM1 as prognostic gene in gastric cancer by co-expression network analysis by Wenjuan Li, Hong Gao, Jianjun Liu

“…Data from RNA sequencing and clinical pathological details were acquired from The Cancer Genome Atlas (TCGA) database and the Gene Expression Omnibus (GEO) dataset. …”
Get full text

In silico evaluation of missense SNPs in cancer-associated Cystatin A protein and their potential to disrupt Cathepsin B interaction by Shafaat Hossain, Omar Hamza Bin Manjur, Mst Sharmin Sultana Shimu, Tamanna Sultana, Mustafizur Rahman Naim, Shahariar Siddique, Abdullah Al Mamun, Md Miftaur Rahman, Md Abu Saleh, Md Rakibul Hasan, Tania Rahman

“…These findings suggest that the E94K mutation could affect the protein structure and cathepsin B interaction, potentially leading to pathological consequences as evidenced by colorectal adenocarcinoma patients in the COSMIC (Catalogue of Somatic Mutations in Cancer) database.…”
Get full text

Hyperthermia and targeting heat shock proteins: innovative approaches for neurodegenerative disorders and Long COVID by David M. Smadja, David M. Smadja, M. Marc Abreu, M. Marc Abreu

“…HSPs such as HSP70 and HSP90 play pivotal roles in protein folding, aggregation prevention, and cellular protection, directly targeting pathological processes seen in NDs like Alzheimer's, Parkinson's, and Huntington's disease. …”
Get full text

Gut microbial subtypes and clinicopathological value for colorectal cancer by Shuwen Han, Jing Zhuang, Yifei Song, Xinyue Wu, Xiaojian Yu, Ye Tao, Jian Chu, Zhanbo Qu, Yinhang Wu, Shugao Han, Xi Yang

“…., free fatty acids and total cholesterol) and CRC pathological information (e.g., tumor depth) varied among gut microbial subtypes. …”
Get full text

Dexmedetomidine alleviates acute kidney injury in a rat model of veno‐arterial extracorporeal membrane oxygenation by Min Yu, Shilin Wei, Xueyang Shen, Junjie Ying, Dezhi Mu, Xiangyang Wu, Yongnan Li

“…Immunohistochemical staining was used to evaluate neutrophil infiltration in the kidney. Results The pathological Paller score was substantially lower in the ECMO + DEX group. …”
Get full text

Prevalence of supernumerary teeth among a sample of patients attending college of dentistry in Erbil, Iraq by Fighan Jalal Hussein, Heran Ibrahim Hassan, Alaa Mahmud Mustafa

“…Conclusion: The identification of this anomaly provides a clue towards the possibility of any complication, pathologies, other related dental anomalies, syndromes and familial association in Erbil, Iraq. …”
Get full text

A New Method of Evaluating the Symmetry of Movement Used to Assess the Gait of Patients after Unilateral Total Hip Replacement by Slawomir Winiarski, Alicja Rutkowska-Kucharska, Andrzej Pozowski, Krzysztof Aleksandrowicz

“…Regions of the greatest asymmetry in pathological movements are usually different from the region of the greatest range of motion. …”
Get full text

DIGITAL AND ESTHETIC APPROACHES TO THE ASSESSMENT OF GINGIVAL AND DENTAL PARAMETERS by Andra Ardelean, Roxana Buzatu, Otilia-Cornelia Bolos, Laura-Cristina Rusu, Anca Tudor, Marius Traian Leretter

“…Aim of the study: The aim of the study was to evaluate the main dental and gingival parameters in order to quantify the differences between genders and between symmetrical elements on the two hemiarches.Materials and methods: The study was conducted on a sample of 52 patients (20 men and 32 women) without periodontal pathologies, dental abrasions, and with properly aligned maxillary teeth. …”
Get full text

Impact of metformin on disease control and survival in patients with head and neck cancer: a retrospective cohort study by Daniel J. Lee, Caitlin P. McMullen, Andrew Foreman, Shao Hui Huang, Lin Lu, Wei Xu, John R. de Almeida, Geoffrey Liu, Scott V. Bratman, David P. Goldstein

“…Patients were well-matched in terms of clinical, pathologic, and treatment factors. No difference in local, regional, or distant failure was observed between diabetic metformin users and diabetic non-metformin users for the entire cohort or within subgroup analysis for subsite. …”
Get full text

Perceptions and attitudes towards AI among trainee and qualified radiologists at selected South African training hospitals by Ayanda I. Nciki, Linda T. Hlabangana

“…Participants agreed that AI could reliably detect pathological conditions (89%), reach reliable diagnosis (89%), improve daily work (78%), and 89% favoured AI practice; 89% believed that in the future, machine learning will not be independent of the radiologist. …”
Get full text

Placenta-derived mesenchymal stem cells protect against diabetic kidney disease by upregulating autophagy-mediated SIRT1/FOXO1 pathway by Honghong Liu, Jiao Wang, Guanru Yue, Jixiong Xu

“…The urine microalbumin/creatinine ratio was determined using ELISA, and renal pathological changes were detected by special staining techniques. …”
Get full text

Fish Tank Granuloma Presenting as a Nasal Cavity Mass by Motoki Sekine, Fumiyuki Goto, Kosuke Saito, Shoji Kaneda, Hikaru Yamamoto, Tomoaki Murakami, Takahide Hamano, Kenji Okami

“…Since the application of steroid ointment did not reduce the size of the mass, the tumor was resected under local anesthesia, and the base was cauterized. The pathological finding was an inflammatory granuloma with negative Ziehl–Neelsen staining. …”
Get full text

Macular Pigment Optical Density in Chinese Primary Open Angle Glaucoma Using the One-Wavelength Reflectometry Method by Yuying Ji, Chengguo Zuo, Mingkai Lin, Xiongze Zhang, Miaoling Li, Lan Mi, Bing Liu, Feng Wen

“…Whether the observed lower MPOD in POAG contributes to the disease process or is secondary to pathological changes caused by the disease (such as loss of ganglion cells) warrants further and longitudinal study.…”
Get full text

Protease-activated receptor 1 in the pathogenesis of cystic fibrosis by Sarath Ranganathan, Philip Sutton, Sophie Day, Poshmaal Dhar, Kristy Azzopardi, Muhammad A Saeed, Sohinee Sarkar, Jia-Xi Han

“…Weight gain in the ilea of Cftr-/- but not DKO mice was associated with increased ileal levels in the pro-inflammatory cytokine interleukin (IL)-6.Conclusions This study provides the first evidence of PAR1 contributing to the pathological effects of Cftr deficiency in the intestine and suggests a possible effect of PAR1 on the regulation of IL-6 in CF pathogenesis.…”
Get full text

Fibrinogen and Albumin Score Changes during Preoperative Treatment Can Predict Prognosis in Patients with Locally Advanced Rectal Cancer by Meng-Jun Tang, Shu-Bo Ding, Wang-Yuan Hu

“…In multivariate analysis, changes in FA scores, pretreatment carcinoembryonic antigen (CEA) levels, and pathologic differentiation were independent prognostic parameters for DFS and changes in FA scores and pretreatment CEA levels were independent prognostic parameters for OS. …”
Get full text

The problem of rare tumors in gynecology: a clinical case of benign retroperitoneal sclerosing pelvic pecoma in 49-year-old woman by V. I. Lanchinsky, Yu. V. Chushkov, A. B. Ponomarev, Yu. I. Osmanov, A. I. Ishchenko, N. V. Vorobev

“…It is noted that among the pelvic organs the uterus is affected most often, but furthermore, the pelvic lymph nodes, the broad ligament, the omentum, the peritoneum of the pelvis and the rectum wall can be also involved in the pathological process. Risk factor of pecomas malignancy is discussed separately, the presence of three types of pecomas is determined. …”
Get full text

Molecular Circuits of Resolution in the Eye by Elvira L. Liclican, Karsten Gronert

“…Protective endogenous roles of LXA4 and NPD1 have been established utilizing lipidomic analysis, knockout mice, and pharmacological, genetic, and dietary manipulation, providing compelling evidence that these intrinsic lipid autacoid circuits play essential roles in restraining inflammation, promoting wound healing, inhibiting pathological angiogenesis, and providing neuroprotection in the delicate visual axis.…”
Get full text

Elective Cesarean Section during Preterm Prevents Pulmonary Hypoplasia Development in Potter Sequence by Yuya Kinoshita, Rieko Sakamoto, Yusuke Hattori, Keishiro Furuie, Shohei Kuraoka, Yuko Hidaka, Hiroshi Tamura, Hiroshi Mitsubuchi, Kimitoshi Nakamura

“…Presently, patients with oligohydramnios showing similar pathological manifestations due to oligohydramnios caused by conditions other than bilateral renal aplasia have been reported, and are known as the Potter sequence. …”
Get full text

Intestinal Schwannoma: A Clinicopathological, Immunohistochemical, and Prognostic Study of 9 Cases by Zhenbo Shu, Chunsheng Li, Mingze Sun, Zhongmin Li

“…Two patients underwent endoscopic biopsy, and the pathological results revealed inflammation and necrosis. …”
Get full text

Exploring changes in metabolites and fecal microbiota of advanced gastric cancer based on plasma metabolomics and 16S rDNA sequencing by Xinyi Feng, Yu Zhang, Jun Feng, Zhongjun Li, Zhi Zhang, Lin Zhu, Ruoyu Zhou, Haibo Wang, Xiaojun Dai, Yanqing Liu

“…This deepens our understanding of the physiological and pathological mechanisms of advanced gastric cancer and helps to improve the diagnosis and treatment of advanced gastric cancer.…”
Get full text