The Gut Microbiota in Women Suffering from Gestational Diabetes Mellitus with the Failure of Glycemic Control by Lifestyle Modification by Guangyong Ye, Long Zhang, Min Wang, Yunbo Chen, Silan Gu, Keyi Wang, Jianhang Leng, Yujia Gu, Xinyou Xie

“…Gut bacteria may participate in the pathological development of GDM2 through the peroxisome proliferator-activated receptor (PPAR) signaling pathway. …”
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Pharmacokinetics of Transdermal Flunixin Meglumine Following a Single Dose in Marine Toads (Rhinella marina) by Gregory Scott, Meghan M. Louis, Julie A. Balko, Claire M. Bublitz, Brigid V. Troan, Ronald E. Baynes, Dustin Smith, Larry J. Minter

“…A single topical dose of transdermal flunixin meglumine was rapidly absorbed in marine toads in the current study, and peak plasma concentrations exceeded therapeutic ranges established in cattle with no significant pathologic findings.…”
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Study of cultural properties of canine enteric coronavirus isolate in different cell cultures by A. A. Komarova, T. S. Galkina

“…TheCCoV isolate recovered from the pathological material of a dead puppy with enteritis symptoms was used in the study. …”
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Phylogenetic analysis and protective effects of thymol and its chromatographic fractions from a novel wild mushroom in combating oxidative stress by M. Subbulakshmi, Sugapriya Dhanasekaran, S. Abirami, M. Kannan, R. Palaniappan, Divya Venugopal

“…The application of thymol natural products from novel mushroom SMK-1 as nutrition supplements could inhibit oxidative stress triggered by numerous pathologies that may pave the way to develop a new therapeutic natural drug.…”
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Targeted therapy for cisplatin‐resistant lung cancer via aptamer‐guided nano‐zinc carriers containing USP14 siRNA by Xinmin Zhao, Xianghua Wu, Huijie Wang, Songtao Lai, Jialei Wang

“…Ubiquitin‐specific protease (USP14) is involved in various pathological conditions including cancer; however, the role of USP14 in NSCLC remains elusive. …”
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Gut microbiota in the association between obesity and kidney function decline: a metagenomics-based study in a rat model by Akehu Alemasi, Lijiang Gu, Yilun Zhou

“…Additionally, the HFD rats exhibited a significantly larger glomerular diameter compared to the ND group, accompanied by the presence of glomerulosclerosis, tubular vacuolar transformation, and other pathological changes in certain glomeruli. Metagenomics analysis revealed a notable rise in the prevalence of the Firmicutes phylum within the HFD group, primarily comprising the Rumenococcus genus. …”
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Anatomical alterations: biparietal thinning in antiquity. Review of published cases and a new case by Nicol Rossetti, Roberta Fusco, Arianna Vanni, Francesca Garanzini, Alessandra Mazzucchi, Marta Licata

“…By presenting this new case, we aim to stimulate further research into biparietal thinning and similar cranial pathologies, enriching the broader narrative of human health evolution.…”
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Evaluation of furniture used by old people in sitting by Maria Luísa Guillaumon Emmel, Luciana Bolzan Agnelli Martinez, Luiza Oliva Paganelli

“…Aging is a dynamic and progressive process, in which there are morphological, functional, biochemical and psychological changes that lead to greater vulnerability and higher incidence of pathological processes. Considering this, one sees the need to provide some care for promoting a healthy aging. …”
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Patient-derived iPSCs link elevated mitochondrial respiratory complex I function to osteosarcoma in Rothmund-Thomson syndrome. by Brittany E Jewell, An Xu, Dandan Zhu, Mo-Fan Huang, Linchao Lu, Mo Liu, Erica L Underwood, Jun Hyoung Park, Huihui Fan, Julian A Gingold, Ruoji Zhou, Jian Tu, Zijun Huo, Ying Liu, Weidong Jin, Yi-Hung Chen, Yitian Xu, Shu-Hsia Chen, Nino Rainusso, Nathaniel K Berg, Danielle A Bazer, Christopher Vellano, Philip Jones, Holger K Eltzschig, Zhongming Zhao, Benny Abraham Kaipparettu, Ruiying Zhao, Lisa L Wang, Dung-Fang Lee

“…Here, we generated RTS patient-derived induced pluripotent stem cells (iPSCs) to dissect the pathological signaling leading to RTS patient-associated osteosarcoma. …”
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Medicalização do parto: a apropriação dos processos reprodutivos femininos como causa da violência obstétrica by Kenia Martins Pimenta Fernandes, Carlos Mendes Rosa

“…The medicalization of childbirth, as a result of social medicalization that attributes medical and pathological characteristics to natural aspects of life, was marked by the removal of midwives from the management of labor, which then became a predominantly male knowledge, given the prohibition of formal education for women. …”
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Choroidal and Retinal Thickness of Highly Myopic Eyes with Early Stage of Myopic Chorioretinopathy: Tessellation by Yanping Zhou, Minlu Song, Minwen Zhou, Yiming Liu, Fenghua Wang, Xiaodong Sun

“…CT may serve as an early pathologic predictor of high myopia.…”
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Impulsive-Compulsive Behaviours in Belgian-Flemish Parkinson’s Disease Patients: A Questionnaire-Based Study by Emke Maréchal, Benjamin Denoiseux, Ellen Thys, Patrick Cras, David Crosiers

“…In 15 patients (17%), a positive QUIP score for one or more impulse control disorders (ICD) was noted: pathological gambling in 1, hypersexuality in 8, compulsive shopping in 5, and compulsive eating in 8 patients. …”
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Wide-Field Megahertz OCT Imaging of Patients with Diabetic Retinopathy by Lukas Reznicek, Jan P. Kolb, Thomas Klein, Kathrin J. Mohler, Wolfgang Wieser, Robert Huber, Marcus Kernt, Josef Märtz, Aljoscha S. Neubauer

“…Due to the densely sampled OCT volume dataset, postprocessed customized cross-sectional B-frames through pathologic changes such as an individual microaneurysm or a retinal neovascularization could be imaged. …”
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An overview of methods for the treatment and diagnosis of dementia with Lewy bodies. Clinical case analysis by M. Š. Markevičiūtė, M. Karnickas, A. Bagdonaitė

“… Dementia with Lewy bodies (DLB) is a progressive neurodegenerative, rarely diagnosed dementia of unknown origin that manifests as fluctuations in cognitive function, complex visual hallucinations, parkinsonism, and REM sleep behavior disorder. A distinctive pathological feature of DLB is the multiple Lewy bodies – eosinophilic hyaline inclusions in the cytoplasm of neurons that are detected in the brain at autopsy. …”
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Surgical treatment of the fistulizing Crohn's disease with anterior abdominal wall reconstruction (Clinical case) by Yu. Ye. Kitsenko, O. S. Shifrin, P. V. Tsarkov

“…Surgical treatment of fistulizing Crohn's disease with interorgan and external fistulas with development of pathological cavity having anterior abdominal wall opening is described. …”
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Cognitive dysfunction in diabetes – the ‘forgotten’ diabetes complication: a narrative review by Åke Sjöholm, Louise Bennet, Peter M. Nilsson

“…Recent years have seen research that has clarified cerebral insulin resistance and defective insulin signaling as examples of pathogenic factors behind this cognitive impairment in diabetes.Method We provide a narrative review of select and contemporary publications with relevance for the interface between diabetes/prediabetes and cognitive function.Results Recently published studies show that physical activity can reverse insulin resistance in the brain as well as cognitive impairment and pathological appetite regulation. Pharmacological interventions with, for example, nasal insulin, GLP-1 receptor agonists, SGLT-2 inhibitors, or PPAR-γ agonists have also shown promising results.Conclusion Optimization of lifestyle factors (e.g. physical activity), as well as several pharmaceutical agents already in clinical use against diabetes, have shown promising results in improving cognitive function in diabetic patients. …”
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Functional Metaplasticity of Hippocampal Schaffer Collateral-CA1 Synapses Is Reversed in Chronically Epileptic Rats by Mirko Rehberg, Timo Kirschstein, Xiati Guli, Steffen Müller, Marco Rohde, Denise Franz, Tursonjan Tokay, Rüdiger Köhling

“…Our study demonstrates age-dependent functional metaplasticity following a spatial memory training task and its reversal under pathological conditions.…”
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Astragaloside IV inhibits atherosclerosis caused by ferritin autophagy in a lipid deposition environment by activating Nrf2 by Dandan Liu, Hewei Qin, Guanghua Liu, Yang Gao, Yu Guo

“…Lipid profile (TC, TG, LDL-C, HDLC), HE and local oil red O showed a reduction in atherosclerotic pathological damage and lipid deposition after astragaloside IV treatment. …”
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Identification of Differentially Expressed lncRNAs in a CpG ODN-Activated Macrophage by Ying Zheng, Xi Luo, Zailong Qin, Zhiguang Zhou

“…Long noncoding RNA (lncRNA) is a novel class of noncoding RNA, whose length is more than 200 nt, but without protein-coding capacity. lncRNAs are involved in many physiological and pathological processes, including inflammatory responses. …”
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Integrated Evaluation of Age-Related Changes in Structural and Functional Vascular Parameters Used to Assess Arterial Aging, Subclinical Atherosclerosis, and Cardiovascular Risk in... by Daniel Bia, Yanina Zócalo, Ignacio Farro, Juan Torrado, Federico Farro, Lucía Florio, Alicia Olascoaga, Javier Brum, Walter Alallón, Carlos Negreira, Ricardo Lluberas, Ricardo L. Armentano

“…A conservative approach was used and people with nonphysiological and pathological conditions were excluded. Then, we excluded subjects with (a) cardiovascular (CV) symptoms, (b) CV disease, (c) diabetes mellitus or renal failure, and (d) traditional CV risk factors (other than age and gender). …”
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