Ileostomy Prolapse in Children with Intestinal Dysmotility by Eric A. Sparks, Cristine S. Velazco, Brenna S. Fullerton, Jeremy G. Fisher, Faraz A. Khan, Amber M. Hall, Tom Jaksic, Leonel Rodriguez, Biren P. Modi

“…Primary outcome was pathologic stoma prolapse. Multivariate analysis using a logistic regression model and log-rank test to compare stoma prolapse rates over time between motility groups were used. …”
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Beyond Tumors: The Pivotal Role of TRIM Proteins in Chronic Non-Tumor Lung Diseases by Huang X, Yu W, Wei A, Wang X, Chen S

“…TRIM proteins modulate key pathological processes, including inflammation, fibrosis, and cellular remodeling, contributing to disease progression. …”
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Enhancing paddy leaf disease diagnosis -a hybrid CNN model using simulated thermal imaging by Jagamohan Padhi, Kunal Mishra, Ashoka Kumar Ratha, Santi Kumari Behera, Prabira Kumar Sethy, Aziz Nanthaamornphong

“…This research underscores the value of integrating thermal imaging with Deep Learning for advancing crop disease management and offers a framework for addressing other crop pathologies.…”
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Immune cell profiles and predictive modeling in osteoporotic vertebral fractures using XGBoost machine learning algorithms by Yi-Chou Chen, Hui-Chen Su, Shih-Ming Huang, Ching-Hsiao Yu, Jen-Huei Chang, Yi-Lin Chiu

“…Moreover, the interaction between immune cells and bone cells plays a crucial role in bone repair processes, highlighting the importance of osteoimmunology in understanding and treating bone pathologies. Methods This study aims to investigate the xCell signature-based immune cell profiles in osteoporotic patients with and without vertebral fractures, utilizing advanced predictive modeling through the XGBoost algorithm. …”
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FlashTag-mediated Labeling for Intraventricular Macrophages in the Embryonic Brain by Hisa Asai, Mizuki Ono, Takaki Miyata, Yuki Hattori

“…Microglia, the brain's immune cells, which play pivotal roles in both physiological and pathological contexts, begin colonizing the brain around embryonic day (E) 9.5 in mice, with their population expanding as development progresses. …”
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From the right ventricle to the descending aorta: a Case Report of complex thrombotic events in a patient with nephrotic syndrome by Jiaojiao Chen, Longyin Zhu, Fen Zhou, Yuting Li, Tao Gu, Jing Xia

“…The etiological diagnosis was hepatitis B virus-associated glomerulonephritis, and the pathological diagnosis was mesangial proliferative glomerulonephritis. …”
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MicroRNA-132 Interact with p250GAP/Cdc42 Pathway in the Hippocampal Neuronal Culture Model of Acquired Epilepsy and Associated with Epileptogenesis Process by Jinxian Yuan, Hao Huang, Xin Zhou, Xi Liu, Shu Ou, Tao Xu, Ruohan Li, Limin Ma, Yangmei Chen

“…Increasing evidence suggests that epilepsy is the result of synaptic reorganization and pathological excitatory loop formation in the central nervous system; however, the mechanisms that regulate this process are not well understood. …”
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Elevated ALOX12 in renal tissue predicts progression in diabetic kidney disease by Meixi Wang, Jingjing Wang, Jinni Wang, Yonggui Wu, Xiangming Qi

“…Clinical chemical and pathological data analysis indicated a correlation between ALOX12 protein expression and renal tubule injury. …”
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Individualized brain radiomics-based network tracks distinct subtypes and abnormal patterns in prodromal Parkinson's disease by Lin Hua, Canpeng Huang, Xinglin Zeng, Fei Gao, Zhen Yuan

“…Individuals in the prodromal phase of Parkinson's disease (PD) exhibit significant heterogeneity and can be divided into distinct subtypes based on clinical symptoms, pathological mechanisms, and brain network patterns. …”
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MicroRNA-208a Dysregulates Apoptosis Genes Expression and Promotes Cardiomyocyte Apoptosis during Ischemia and Its Silencing Improves Cardiac Function after Myocardial Infarction by Hasahya Tony, Kai Meng, Bangwei Wu, Aijia Yu, Qiutang Zeng, Kunwu Yu, Yucheng Zhong

“…Aims. miR-208a is associated with adverse outcomes in several cardiac pathologies known to have increased apoptosis, including myocardial infarction (MI). …”
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African swine fever in the Republic of Crimea in 2015–2018 by N. G. Kosharny, S. I. Danylchenko, M. A. Pasunkina, D. V. Gadzevich, N. G. Vorotilova

“…In 2018, ASF virus was detected with polymerase chain reaction (PCR) in 8 samples of pathological materials from wild boars, that was 0.1% out of total number of the samples tested in the FGBI “ARRIAH” Branch in the Republic of Crimea and FGI RC “Regional State Veterinary Laboratory of the Republic of Crimea”. …”
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GLI1-altered mesenchymal tumor involving the parietal pleura: case report and literature review by Yuanli Zhong, Baizhou Li, Gangping Wang, Yuqing Liu, Zhenwei Chen

“…These tumors are predominantly located in the head and neck region and display distinctive pathological morphology and molecular characteristics. …”
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Asymptomatic Hyperuricemia Is Associated with Achilles Tendon Rupture through Disrupting the Normal Functions of Tendon Stem/Progenitor Cells by Jingjing Liang, Biao Chen, Yanmei Li, Daibang Nie, Changbin Lei, Qing Yang, Yiqin Zhou, Shenglong Li, Shuaizhi Chen, Bin Li, Lin Shu, Liaobin Chen, Wang Wang

“…Here, we investigated whether asymptomatic hyperuricemia was associated with spontaneous ruptures in the Achilles tendon and the pathological effect of hyperuricemia on the tendon stem/progenitor cells (TSPCs). …”
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Controversial Roles of Regenerating Family Proteins in Tissue Repair and Tumor Development by Luting Yu, Qingyun Wu, Shenglong Jiang, Jia Liu, Junli Liu, Guoguang Chen

“…<b>Conclusions</b>: Reg proteins have dual functional roles under various physiological and pathological conditions. These theoretical foundations facilitate the subsequent development of diagnostic reagents and therapeutic drugs targeting Reg proteins.…”
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Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity by Evelyn F Okal, Philip A. Romero, Pete Heinzelman

“…Abstract Background Angiotensin-Converting Enzyme 2 (ACE2) is a crucial peptidase in human peptide hormone signaling, catalyzing the conversion of Angiotensin-II to Angiotensin-(1–7), which activates the Mas receptor and elicits vasodilation, increased blood flow, reduced inflammation, and decreased pathological tissue remodeling. This study leverages protein engineering to enhance ACE2’s therapeutic potential for treating conditions such as respiratory viral infections, acute respiratory distress syndrome, and diabetes. …”
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Bilateral inguinal hernioplasty in emergency surgery: Is it feasible? Comparative retrospective study using “propensity score matching” by A. Bravo-Salva, F. Ochoa-Segarra, A. M. González-Castillo, M. Juvany-Gómez, C. Téllez-Marques, L. Riba-Combatti, M. Pérez-Guitart, J. A. Pereira-Rodríguez

“…INTRODUCTION: Hernias, particularly groin hernias, are prevalent surgical pathologies worldwide, often necessitating surgery in cases of complications. …”
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Anisodamine ameliorates crystalline silica-exposed pulmonary inflammation and fibrosis via the α7nAChR/JAK2/STAT3 signaling pathway by Meng Liu, Hui Liu, Hong Kang, Juan Wu, Puhua Xing, Xiaorui Ding, Yangyang Wei, Xiaomei Kong

“…Animal experiments demonstrated that ANI significantly reduced alveolar structure damage and the formation of silicosis nodules in affected mice, as confirmed by pathological slides. ANI inhibited the expression of tumor necrosis factor (TNF-α) in bronchoalveolar lavage fluid (BALF) while promoting the secretion of interleukin-4 (IL-4) and interleukin-10 (IL-10). …”
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Study of Zuojin Pill in Treating Chronic Atrophic Gastritis by UPLC-Q-TOF/MS Based on Serum and Urine Metabolomics Combined with Network Pharmacology by Shihua Wu, Xing Chen, Honghong Liu, Ruilin Wang, Jianyu Li, Jianxia Wen, Tao Yang, Ying Wei, Sichen Ren, Shizhang Wei, Manyi Jing, Haotian Li, Min Wang, Houlin Xia, Yanling Zhao

“…ZJP and omeprazole significantly reduce contents of IL-1β, IL-6, IL-10, and iNOS and improve pathological characteristics. Metabolomic results indicated that the therapeutic effects of ZJP were mainly related to ten metabolites, namely, choline, L-threonine, hydroxypyruvic acid, creatine, taurine, succinic acid, cis-aconitic acid, citric acid, succinic acid semialdehyde, and uric acid. …”
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Interleukin-17: Potential Target for Chronic Wounds by Yasmin Hadian, Michelle D. Bagood, Sara E. Dahle, Apra Sood, R. Rivkah Isseroff

“…The published work supports a pathologic role for interleukin-17 family members in chronic wounds, though this needs to be more conclusively proven. …”
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Ventricular Depolarization Abnormalities and Their Role in Cardiac Risk Stratification — A Narrative Review by Maarten Blondeel, Tomas Robyns, Rik Willems, Bert Vandenberk

“…Abnormalities in ventricular depolarization may indicate various pathologies and can be present in all leads if the condition is general, or in a subgroup of anatomically contiguous leads if the condition is limited to the corresponding anatomic location of the heart. …”
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