Delayed Manifestation of Shunt Nephritis: A Case Report and Review of the Literature by Michael Babigumira, Benjamin Huang, Sherry Werner, Wajeh Qunibi

“…In this review, we comment on the presentation, lab findings, pathological features, and management of this rare, potentially fatal, but curable disease entity.…”
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Maternal Hypertension and Early Atherosclerotic Lesions in Aortas of Deceased Fetuses and Neonates by Janet María Capote-Santa Cruz Pacheco, Carmen Teresa Peraza Méndez, Marlene Ferrer Arrocha, Lisandra Álvarez de la Nuez, Belkis Ortega de la Campa, Mirian Castro Ortega

“…<br /><strong>Method:</strong> a descriptive cross-sectional study was carried out that included fetuses older than 22 weeks and deceased neonates born to hypertensive mothers, who underwent autopsy in the pathological anatomy department of the Eusebio Hernández Pérez Gynecobstetric University Hospital, in the period between January 2021 and December 2022, with a total of 18. …”
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Integrated Analysis of microRNA Targets Reveals New Insights into Transcriptional–Post-Transcriptional Regulatory Cross-Talk by Simona Panni, Roberto Pizzolotto

“…Despite their undeniable relevance and the substantial body of literature demonstrating their role in cancer and other pathologies, the identification of functional interactions is still challenging. …”
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Osteoporosis in Rett Syndrome: A Study on Normal Values by Lilit Zysman, Meir Lotan, Bruria Ben-Zeev

“…This condition may cause pathological fractures, inflict pain, and seriously damage mobility. …”
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STAT3 inhibition ameliorates renal interstitial inflammation in MRL/lpr mice with diffuse proliferative lupus nephritis by Jianfen Zhu, Yijing Chen, Yulan Chen, Yinqiu Lv, Tianxin Chen

“…However, the specific therapy and mechanisms of AKI in DPLN remain to be explored.Methods The correlation between AKI and clinical pathological changes in DPLN patients was analyzed. Expression of STAT3 signaling was detected in MRL/lpr mice with DPLN using immunohistochemical staining and immunoblotting. …”
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Chronic Mild Stress Modulates Activity-Dependent Transcription of BDNF in Rat Hippocampal Slices by Raffaella Molteni, Andrea C. Rossetti, Elisa Savino, Giorgio Racagni, Francesca Calabrese

“…Although activity-dependent transcription represents a crucial mechanism for long-lasting experience-dependent changes in the hippocampus, limited data exist on its contribution to pathological conditions. We aim to investigate the influence of chronic stress on the activity-dependent transcription of brain-derived neurotrophic factor (BDNF). …”
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New Predictive Factors in the Development of Type 2 Diabetes Mellitus by Maurio González Hernández

“…<strong><br />Conclusions:</strong> among the new predictive factors for the development of type 2 diabetes mellitus are: the value of microalbuminuria, periodontal disease, sensitivity disorders in the lower limbs, a pathological history of hypothyroidism and eye fundus alterations.…”
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Cyclin-dependent protein kinases and cell cycle regulation in biology and disease by Ilenia Pellarin, Alessandra Dall’Acqua, Andrea Favero, Ilenia Segatto, Valentina Rossi, Nicole Crestan, Javad Karimbayli, Barbara Belletti, Gustavo Baldassarre

“…We then discuss the potential roles and deregulation of CDKs in human pathologies, with a particular focus on cancer, the human disease in which CDKs have been most extensively studied and explored as therapeutic targets. …”
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Bile Reflux Gastritis: Insights into Pathogenesis, Relevant Factors, Carcinomatous Risk, Diagnosis, and Management by Xiaolan Shi, Zijiao Chen, Yi Yang, Su Yan

“…Nevertheless, advances in techniques, especially extensive applications of endoscopy and chemical analysis of reflux contents, have improved our ability to identify the occurrence of this disease as well as distinguishing physiological reflux from pathological reflux. Finally, it is fortunate for patients that more and more importance has been attached to the treatment of BRG. …”
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Electroacupuncture Treatment Alleviates Central Poststroke Pain by Inhibiting Brain Neuronal Apoptosis and Aberrant Astrocyte Activation by Gui-Hua Tian, Shan-Shan Tao, Man-Tang Chen, Yu-Sang Li, You-Ping Li, Hong-Cai Shang, Xiao-Yi Tang, Jian-Xin Chen, He-Bin Tang

“…Together, these findings suggest that CPSP is closely related to pathological changes of the neocortex and hippocampus. …”
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The Predictive and Prognostic Factors in Patients with Gastric Cancer Accompanied by Gastric Outlet Obstruction by Hongliang Zu, Huiling Wang, Chunfeng Li, Wendian Zhu, Yingwei Xue

“…The patients with distal gastric cancer with GOO generally presented more aggressive pathologic features, a poorer nutritional status, more duodenal infiltration, and peritoneal dissemination than those with cancer without GOO. …”
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Neurochemical Plasticity of the Coeliac-Superior Mesenteric Ganglion Complex Neurons Projecting to the Prepyloric Area of the Porcine Stomach following Hyperacidity by Katarzyna Palus, Jarosław Całka

“…These findings enrich existing knowledge about the participation of these active substances in adaptive mechanism(s) of the sympathetic neurons during pathological processes within the gastrointestinal tract.…”
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Association of Premature Ventricular Contraction (PVC) with hematological parameters: a data mining approach by Nafiseh Hosseini, Sara Saffar Soflaei, Pooria Salehi-Sangani, Mahdiyeh Yaghooti-Khorasani, Bahram Shahri, Helia Rezaeifard, Habibollah Esmaily, Gordon A. Ferns, Mohsen Moohebati, Majid Ghayour-Mobarhan

“…However, it may be associated with some pathological conditions. In this research the association between hematological factors and PVC was studied. …”
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The Efficacy of Denosumab in the Management of a Tibial Paediatric Aneurysmal Bone Cyst Compromised by Rebound Hypercalcaemia by Matthew Harcus, Samantha Aldridge, Adesegun Abudu, Lee Jeys, Senthil Senniappan, Henry Morgan, Barry Pizer

“…The patient had ongoing severe pain, was unable to weight-bear, and was at significant risk of pathological fracture. En bloc resection and embolization were not deemed viable, and a decision to use denosumab was made. …”
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Local Overexpression of Interleukin-11 in the Central Nervous System Limits Demyelination and Enhances Remyelination by Anurag Maheshwari, Kris Janssens, Jeroen Bogie, Chris Van Den Haute, Tom Struys, Ivo Lambrichts, Veerle Baekelandt, Piet Stinissen, Jerome J. A. Hendriks, Helena Slaets, Niels Hellings

“…Demyelination is one of the pathological hallmarks of multiple sclerosis (MS). To date, no therapy is available which directly potentiates endogenous remyelination. …”
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Diagnostic Value of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in the Evaluation of the Biliary Obstruction by Mehmet Bilgin, Hüseyin Toprak, Mehmet Burgazli, S. Sennur Bilgin, Ritvan Chasan, Ali Erdogan, Cem Balci

“…MRCP images were evaluated together with the T1 and T2w images, and both biliary ducts and surrounding tissues were examined for possible pathologies that may cause obstruction. Results. MRI/MRCP findings compared with final diagnoses, MRI/MRCP in the demonstration of bile duct obstruction sensitivity 96%, the specificity 100%, and accuracy 96.3%, in the detection of presence and level of obstruction, the sensitivity 96.7%, specificity 100%, and accuracy 97.2%, in the diagnosis of choledocholithiasis, the sensitivity 82.3%, specificity 96%, and accuracy 91.7%, and in the determination of the character of the stenosis, sensitivity 95.6%, specificity 91.3%, and accuracy 94.5% were found. …”
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FGF2 Attenuates Neural Cell Death via Suppressing Autophagy after Rat Mild Traumatic Brain Injury by Chonghui Tang, Yudong Shan, Yilan Hu, Zhanjian Fang, Yun Tong, Mengdan Chen, Xiaojie Wei, Xiaojun Fu, Xinlong Xu

“…One hundred and forty-four rats were used for creating controlled cortical impact (CCI) models to simulate the pathological damage after TBI. Our results indicated that pretreatment of FGF2 played a neuroprotective role in the early stage of rat mild TBI through alleviating brain edema, reducing neurological deficits, preventing tissue loss, and increasing the number of surviving neurons in injured cortex and the ipsilateral hippocampus. …”
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Evaluating the Correlation between Overjet and Skeletal Parameters Using DVT by Luca Lombardo, Chiara Sgarbanti, Antonio Guarneri, Giuseppe Siciliani

“…A sample of 42 subjects, all in complete permanent dentition and without a history of orthodontic treatment or systemic pathologies, was subdivided into 2 groups: group 1 consisted of 25 subjects with ANB angle 0°–4° (skeletal class I), and group 2 was made up of 17 subjects with ANB angle >4° (skeletal class II). …”
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Phase-Amplitude Coupling of Neural Oscillations Can Be Effectively Probed with Concurrent TMS-EEG by Sarah Glim, Yuka O. Okazaki, Yumi Nakagawa, Yuji Mizuno, Takashi Hanakawa, Keiichi Kitajo

“…By indicating that scalp-recorded phase-amplitude coupling can be effectively probed with TMS, these findings open the door to the technique’s application in manipulative dissections of such coupling during human cognition and behaviour in healthy and pathological conditions.…”
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DIAGNOSTIC COMPETENCE IN BONE TUMORS: INFLUENCE OF ONCO-ORTHOPEDIC TRAINING by Julia Pozzetti Daou, Caio Falk Giannotti, Jairo Greco Garcia, Marcelo de Toledo Petrilli, Dan Carai Maia Viola, Reynaldo Jesus Garcia Filho

“…Orthopedists’ ability to identify these pathologies early and accurately is paramount. There is a requirement to raise awareness within the orthopedic community regarding the necessity of referrals to orthopedic oncology specialists, as delays in initiating proper treatment can compromise patient prognosis. …”
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