Cervical Spondylotic Myelopathy Secondary to Dropped Head Syndrome: Report of a Case and Review of the Literature by Abolfazl Rahimizadeh, Housain F. Soufiani, Saghayegh Rahimizadeh

“…In review of the literature, we could find only 5 cases, with no unique guidelines to address the management of these two concomitant pathologies. Herein, a 69-year-old man who had developed cervical myelopathy 2 years after being affected by isolated dropped head syndrome is presented. …”
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Function of Dicer with regard to Energy Homeostasis Regulation, Structural Modification, and Cellular Distribution by Xiaohui Tong, Nianjun Yu, Rongchun Han, Tongsheng Wang

“…As a type III ribonuclease (RNase III) specifically cleaving double-stranded RNA substrates into short fragments, Dicer is indispensable in a range of physi/pathologic processes, e.g., nutrient deprivation, hypoxia, or DNA damage. …”
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Protective Effects of Tormentic Acid on Unilateral Ureteral Obstruction-Induced Renal Injury, Inflammation, and Fibrosis: A Comprehensive Approach to Reducing Oxidative Stress, Apo... by Ah Young Yang, Jung-Yeon Kim, Mi-Gyeong Gwon, Hyun Hee Kwon, Jaechan Leem, Eon-Ju Jeon

“…Tormentic acid (TA), a triterpenoid compound with known anti-inflammatory and antioxidant properties, shows significant potential in counteracting these pathological processes. This study explored the protective role of TA in a unilateral ureteral obstruction (UUO)-induced CKD model. …”
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Spectrum of Chronic Gastritis Based on Morphological Examination of Gastric Biopsies by А. S. Tertychnyy, Т. L. Lapina, D. Р. Nagornaya, N. V. Pachuashvili, А. Р. Kiryukhin, А. А. Fedorenko, Р. V. Pavlov, D. D. Protsenko, V. Т. Ivashkin

“…The study included 3162 individuals who underwent esophagogastroduodenoscopy with biopsy collection between 2017 and 2022. Pathological examination of biopsies was conducted using the updated Sydney system, determining the histological variant and, when possible, the etiology of gastritis. …”
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Chinese Torreya grandis cv. Merrillii seed oil affects obesity through accumulation of sciadonic acid and altering the composition of gut microbiota by Huan Wang, Ye Li, Rui Wang, Huaifei Ji, Chenyang Lu, Xiurong Su

“…Moreover, the oil supplement significantly changed the fatty acid composition and alleviated pathological damage to the liver caused by the high-fat diet. …”
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Do PPAR-Gamma Agonists Have a Future in Parkinson's Disease Therapy? by Anna R. Carta, Augusta Pisanu, Ezio Carboni

“…Moreover, after the discovery of infiltrating activated Limphocytes in the substantia nigra (SN) of PD patients, most recent research supports a role of immune-mediated mechanisms in the pathological process leading to chronic neuroinflammation and dopaminergic degeneration. …”
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Environmental high temperature (heat stroke) causes articular cartilage damage in vivo and in vitro by Sun yingfei, Yang feng, Ma haoning

“…However, up to now, the potential pathological effects of HS on articular cartilage have not been revealed. …”
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Instance-level semantic segmentation of nuclei based on multimodal structure encoding by Bo Guan, Guangdi Chu, Ziying Wang, Jianmin Li, Bo Yi

“…This approach shows significant potential for enhancing histopathological image analysis, potentially leading to more accurate diagnoses and improved understanding of cellular structures in pathological tissues.…”
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Visfatin/Nampt: An Adipokine with Cardiovascular Impact by Tania Romacho, Carlos F. Sánchez-Ferrer, Concepción Peiró

“…Further research is required to fully understand the mechanisms mediating the cellular actions of this adipokine and to better characterize the factors regulating visfatin/Nampt expression and release in all these pathologic scenarios. Only then, we will be able to conclude whether visfatin/Nampt is a therapeutical target in cardiometabolic diseases.…”
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Single-Lung Transplant Results in Position Dependent Changes in Regional Ventilation: An Observational Case Series Using Electrical Impedance Tomography by Kollengode Ramanathan, Hend Mohammed, Peter Hopkins, Amanda Corley, Lawrence Caruana, Kimble Dunster, Adrian G. Barnett, John F. Fraser

“…Positioning in patients with active unilateral lung pathologies will be implicated. This is the first study demonstrating changes in regional ventilation, associated with changes of position between transplanted and diseased lung.…”
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Trimethyltin-Induced Microglial Activation via NADPH Oxidase and MAPKs Pathway in BV-2 Microglial Cells by Da Jung Kim, Yong Sik Kim

“…Microglial activation is one of the prominent pathological features of TMT neurotoxicity. Nevertheless, it remains unclear how microglial activation occurs in TMT intoxication. …”
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Prognostic Value of Melanoma Inhibitory Activity Protein in Localized Cutaneous Malignant Melanoma by Angela Sandru, Eugenia Panaitescu, Silviu Voinea, Madalina Bolovan, Adina Stanciu, Sabin Cinca, Alexandru Blidaru

“…The death risk was 12 times higher in pathological MIA group of patients (P=0.0001). Conclusions. …”
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Amino acid stable carbon isotopes in nail keratin illuminate breastfeeding and weaning practices of mother – infant dyads by Hana Salahuddin, Andrea L. Waters-Rist, Fred J. Longstaffe

“…Additionally, δ 13C values of glycine and glutamate indicate maternal physiological and pathological stress due to catabolic effects such as gluconeogenesis. …”
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Low Infection Rate after Tumor Hip Arthroplasty for Metastatic Bone Disease in a Cohort Treated with Extended Antibiotic Prophylaxis by Werner H. Hettwer, Peter Frederik Horstmann, Thea Bechmann Hovgaard, Tomas Andreas Grum-Scwensen, Michael M. Petersen

“…Our findings suggest that extended postoperative antibiotic prophylaxis may reduce the risk of PJI in patients undergoing tumor resection and endoprosthetic replacement for metastatic bone disease associated impending or de facto pathologic fractures of the proximal femur.…”
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Diabetic Polyneuropathy in Type 2 Diabetes Mellitus: Inflammation, Oxidative Stress, and Mitochondrial Function by Luis Miguel Román-Pintos, Geannyne Villegas-Rivera, Adolfo Daniel Rodríguez-Carrizalez, Alejandra Guillermina Miranda-Díaz, Ernesto Germán Cardona-Muñoz

“…There are three main alterations involved in the pathologic changes of DPN: inflammation, oxidative stress, and mitochondrial dysfunction. …”
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Xeroderma Pigmentosum with Severe Neurological Manifestations/De Sanctis–Cacchione Syndrome and a Novel XPC Mutation by Esteban Uribe-Bojanini, Sara Hernandez-Quiceno, Alicia María Cock-Rada

“…Several genes have been found to be altered in these pathologies, but we lack more genotype-phenotype correlations in order to make an accurate diagnosis. …”
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Placental alterations and their annexes in fetal deaths. Dr. Gustavo Aldereguía Lima Hospital. 2021–2023 by Niuvys Valera Rodríguez, Caridad Socorro Castro, Javier Martínez Navarro, Lisanka Fumero Roldan, Jorge Enrique Rodríguez León

“…Gustavo Aldereguía Lima Hospital, in Cienfuegos, from 2021 to 2023. 58 placentas and their annexes, received in the Pathological Anatomy Department, were analyzed. Macroscopic and microscopic alterations of the placenta were studied.…”
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Modulation of Second Messenger Signaling in the Brain Through PDE4 and PDE5 Inhibition: Therapeutic Implications for Neurological Disorders by Min Kyu Park, Hyun Wook Yang, Seo Young Woo, Dong Yeon Kim, Dae-Soon Son, Bo Young Choi, Sang Won Suh

“…Pharmacological modulation of these enzymes offers potential to enhance cognitive function and mitigate pathological mechanisms underlying brain injuries, neurodegenerative diseases, and psychiatric disorders. …”
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Gastric Endocrine Cell Carcinoma Coexistent with Adenocarcinoma by Nobuhiro Takeuchi, Nomura Yusuke, Tetsuo Maeda, Kazuyoshi Naba

“…Distal gastrectomy with D2 lymph node dissection and Billroth I reconstruction was performed. Pathological examination of the gross specimen revealed that adenocarcinoma comprised <10% of all cancer cells. …”
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Identification of potent TMPRSS4 inhibitors through structural modeling and molecular dynamics simulations by Ismail Hdoufane, Mehdi Oubahmane, Youssef Habibi, Christelle Delaite, Mohammed M. Alanazi, Driss Cherqaoui

“…Abstract TMPRSS4, a transmembrane serine protease type II, is associated with various pathological illnesses. It has been found to activate SARS-CoV-2, enhance viral infection of human small-intestinal enterocytes and is overexpressed in different types of cancers. …”
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