Nanomédicaments pour le traitement de maladies graves et recherches duales by Couvreur, Patrick

“…By releasing the active ingredient at the level of pathological cells and tissues, these nanocarriers help reduce toxicity while improving therapeutic efficacy. …”
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Bifidobacterium breve BB05 alleviates depressive symptoms in mice via the AKT/mTOR pathway by Yanni Pan, Qingling Huang, Yuan Liang, Yuwuqi Xie, Fang Tan, Xingyao Long

“…BB05 treatment also reduced pathological ileal damage, alleviated inflammation, and lowered serum levels of pro-inflammatory cytokines IL-6 and TNF-α. …”
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Pharmacologic Targets and Prototype Therapeutics in the Kallikrein-Kinin System: Bradykinin Receptor Agonists or Antagonists by J. N. Sharma, G.J. AL-Sherif

“…It is a proinflammatory polypeptide that is involved in many pathological conditions and can cause pain, inflammation, increased vascular permeability, vasodilation, contraction of various smooth muscles, as well as cell proliferation. …”
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Impact of surgery on visual acuity and life quality of senile patients by Mariela Julia Curbelo Gómez, Maria Adela Llull Tombo

“…<strong><br />Methods:</strong> A prospective, descriptive, study including variables as age, gender, general and visual personal pathological history of all the patients who attended to the provisional consultation of the General Hospital “Dr. …”
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A Current Review of the Meniscus Imaging: Proposition of a Useful Tool for Its Radiologic Analysis by Nicolas Lefevre, Jean Francois Naouri, Serge Herman, Antoine Gerometta, Shahnaz Klouche, Yoann Bohu

“…Ultrasound is rarely used as a diagnostic tool for meniscal pathologies and its accuracy is operator-dependent. …”
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Understanding the Role of Exercise in Nonalcoholic Fatty Liver Disease: ERS-Linked Molecular Pathways by Yong Zou, Zhengtang Qi

“…Recent studies showed that endoplasmic reticulum stress (ERS) at the subcellular level underlies these featured pathologies in the development of NAFLD. As an effective treatment, exercise significantly reduces hepatic lipid accumulation and thus alleviates NAFLD. …”
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Prepuce: Phimosis, Paraphimosis, and Circumcision by Yutaro Hayashi, Yoshiyuki Kojima, Kentaro Mizuno, Kenjiro Kohri

“…Balanitisxeroticaobliterans is an infiltrative skin condition that causes a pathological phimosis and has been considered to be the only absolute indication for circumcision. …”
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Prenatal maternal stress in rats alters the epigenetic and transcriptomic landscape of the maternal-fetal interface across four generations by Stephanie E. King, Nicola A. Schatz, Olena Babenko, Yaroslav Ilnytskyy, Igor Kovalchuk, Gerlinde A. S. Metz

“…The highly correlated placenta-brain profiles support the use of placenta as a noninvasive biomarker resource to predict pathological changes in the neonatal brain. The transgenerational persistence of critical DNAm, miRNA and mRNA signatures may explain familial non-genetic disease risks.…”
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Is It Necessary to Specifically Define the Cause of Surgically Treated Biliary Tract Infections? A Rare Case of Raoultella planticola Cholecystitis and Literature Review by Suat Can Ulukent, İnanc Samil Sarici, Nuri Alper Sahbaz, Yigit Mehmet Ozgun, Ozlem Akca, Kamuran Sanlı

“…Patient received intravenous antibiotic treatment, but the treatment failed and the patient underwent an open cholecystectomy. The final pathological result was gangrenous cholecystitis complicated with R. planticola. …”
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Liposomal Antioxidants for Protection against Oxidant-Induced Damage by Zacharias E. Suntres

“…This paper focus on the use of liposomes for the delivery of antioxidants in the prevention or treatment of pathological conditions related to oxidative stress.…”
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The link between optic neuritis and multiple sclerosis. Literature review by A. Kubiliūtė, R. Liutkevičienė

“…Immuno-modulated myelin sheathing and axonal loss causing irreversible neurological dysfunction can be found in both pathologies. Patients who experience these conditions are usually young adults, therefore early diagnosis and control of the disease may benefit in preserving their neurological function and quality of life. …”
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Sarcoglycans are enriched at the neuromuscular junction in a nerve-dependent manner by Michela Gloriani, Bianca Cheli, Chiara D’Ercole, Veronica Ruggieri, Marianna Cosentino, Mireia Serrat Pineda, Biliana Lozanoska-Ochser, Francesca Grassi, Marina Bouché, Luca Madaro, Carles Sánchez Riera

“…Altogether, our findings suggest that pathological decline should no longer be understood only in terms of sarcolemma damage but also in terms of sarcoglycans’ participation in the NMJ. …”
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Inhibition of IAPP Aggregation and Toxicity by Natural Products and Derivatives by Amit Pithadia, Jeffrey R. Brender, Carol A. Fierke, Ayyalusamy Ramamoorthy

“…Fibrillar aggregates of human islet amyloid polypeptide, hIAPP, a pathological feature seen in some diabetes patients, are a likely causative agent for pancreatic beta-cell toxicity, leading to a transition from a state of insulin resistance to type II diabetes through the loss of insulin producing beta-cells by hIAPP induced toxicity. …”
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Synthesis and Characterization of Hydrogel-Based Hyaluronic Acid-Chitosan-Allium sativum Extract for Intraperitoneal Antiadhesion Application by Prihartini Widiyanti, Yolanda Citra Ayu Priskawati

“…Peritoneal Adhesion is a severe case that frequently occurs in patients after laparotomy surgery. Adhesions are pathological attachment that usually appears between the omentum, intestine, and abdominal wall. …”
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Organ preservation strategies for rectal cancer treatment: tarts or trap? by ZHOU Yihang, ZENG Ziwei, KANG Liang

“…In recent years, with advancements in neoadjuvant chemoradiotherapy and the implementation of immunotherapy, the pathological complete response (pCR) rate following neoadjuvant therapy for rectal cancer has significantly increased. …”
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A Rare Malignant Peripheral Nerve Sheath Tumor of the Maxilla Mimicking a Periapical Lesion by José Alcides Arruda, Pamella Álvares, Luciano Silva, Alexandrino Pereira dos Santos Neto, Cleomar Donizeth Rodrigues, Antônio Caubi, Marcia Silveira, Sandra Sayão, Ana Paula Sobral

“…Surgical approaches to malignant soft tissue tumor vary based on the extent of the disease, age of the patient, and pathological findings. A rare case of intraosseous malignant peripheral nerve sheath tumor is reported in a 16-year-old woman. …”
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Modeling autoregulation of cardiac excitation-Ca-contraction and arrhythmogenic activities in response to mechanical load changes by Asuka Hatano, Leighton T. Izu, Ye Chen-Izu, Daisuke Sato

“…The model also makes non-trivial predictions on the autoregulation of contraction with moderate MCT-Ca2+ gain under a range of physiological load changes, but arrhythmogenic discordant alternans with excessive MCT-Ca2+ gain under pathological overload.…”
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Electromagnetic Fields, Oxidative Stress, and Neurodegeneration by Claudia Consales, Caterina Merla, Carmela Marino, Barbara Benassi

“…Since free radicals are essential for brain physiological processes and pathological degeneration, research focusing on the possible influence of the EMFs-driven oxidative stress is still in progress, especially in the light of recent studies suggesting that EMFs may contribute to the etiology of neurodegenerative disorders. …”
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Emerging roles of extracellular vesicles in oral and maxillofacial areas by Qianting Wang, Jiayu Sun, Haci Jiang, Mengfei Yu

“…To date, studies have revealed the different roles of extracellular vesicles in physiological or pathological processes, as well as applications in disease diagnosis, prognosis, and treatment. …”
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Natural products targeting ubiquitination to combat kidney fibrosis by Lianhua Li, Xinhui Huang, Yao Chen, Jibin Liu, Yuhang Qiao, Wenyu Fan, Peiqing Zhang, Xiaoming Yan, Ming Chen

“…Abstract Background Kidney fibrosis is a crucial component that contributes to end-stage renal disease and is the inevitable last pathological process in many progressive chronic kidney diseases (CKD). …”
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