Malignant ilnesses in men breast. A twenty-five year study by Lidia Torres Ajá

“…<br /><strong>Objective:</strong> to describe the clinical-pathologic behavior of breast cancer in Cienfuegos province. …”
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A Link between Autophagy and the Pathophysiology of LRRK2 in Parkinson's Disease by Patricia Gómez-Suaga, Elena Fdez, Marian Blanca Ramírez, Sabine Hilfiker

“…The discovery of monogenic forms has significantly advanced our understanding of the molecular mechanisms underlying PD, as it allows generation of cellular and animal models carrying the mutant gene to define pathological pathways. Mutations in leucine-rich repeat kinase 2 (LRRK2) cause dominantly inherited PD, and variations increase risk, indicating that LRRK2 is an important player in both genetic and sporadic forms of the disease. …”
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Trafficking in cancer: from gene deregulation to altered organelles and emerging biophysical properties by Julie Patat, Kristine Schauer, Kristine Schauer, Hugo Lachuer

“…By understanding these parameters, we may gain insights into the mechanisms that lead to a pathological organelle spatial organization, which could help explain the plasticity of cancer cells.…”
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Inflammatory Bowel Disease in Hispanics: The University of Puerto Rico IBD Registry by Esther A. Torres, Abdiel Cruz, Mariola Monagas, Marina Bernal, Yadira Correa, Rafael Cordero, Víctor L. Carlo

“…Subjects with a documented diagnosis of IBD by clinical, radiologic, endoscopic, and/or pathologic criteria were recruited from the IBD clinics, support groups, and community practices, and demographic and medical data was collected. …”
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Extreme Maternal Metabolic Acidosis Leading to Fetal Distress and Emergency Caesarean Section by Nicolas Cecere, Corinne Hubinont, Arnauld Kabulu Kadingi, Marie-Françoise Vincent, Peter Van den Bergh, Anna Onnela, Philippe Hantson

“…As fetal heart monitoring was pathological, an emergency caesarean section was performed. …”
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Cross-Talk between Gut Microbiota and Heart via the Routes of Metabolite and Immunity by Jin Bu, Zhaohui Wang

“…Dysbiosis, characterized by changes in the gut microbiota in CVD, has been reported in cardiovascular pathologies, such as atherosclerosis, hypertension, and heart failure. …”
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Fenofibrate Exerts Antitumor Effects in Colon Cancer via Regulation of DNMT1 and CDKN2A by Rui Kong, Nan Wang, Wei Han, Wen Bao, Jie Lu

“…Recently, the potential role of PPARA in other pathological conditions, such as cancers, has been recognized. …”
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Therapeutic Actions of the Thiazolidinediones in Alzheimer’s Disease by María José Pérez, Rodrigo A. Quintanilla

“…How TZDs may improve or reduce these pathologic signs of AD and what the mechanisms and the implicated pathways in which these drugs work are are questions that remain to be answered. …”
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Aortic Valve Papillary Fibroelastoma Associated with Acute Cerebral Infarction: A Case Report by Nobuhiro Takeuchi, Masanori Takada, Koichi Fujita, Yoshiharu Nishibori, Takao Maruyama, Kazuyoshi Naba

“…Cardiac tumor was considered the cause of cerebral infarction, and the patient consented to surgical therapy. Pathological examination of the resected tumor suggested papillary fibroelastoma (PFE). …”
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Cow milk αs1-casein induces allergic responses in a mouse model of atopy by Guangyu Wang, Xiaofeng Yu, Yanjun Cong, Linfeng Li

“…The levels of specific IgE, mast cell proteinase, histamine and cytokines in sensitized mice were determined, and the clinical and pathological observation were evaluated. Results showed that the levels of specific IgE, mast cell proteinase, histamine, IL-4, IL-5, IL-10 increased significantly with a dose-dependent trend. …”
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Alzheimer’s Dementia due to Suspected CTE from Subconcussive Head Impact by Shauna H. Yuan, Sonya G. Wang

“…Clear clinical diagnostic criteria for CTE have not been established. Only recently, pathological diagnostic criteria have been recognized, but postmortem diagnosis is too late. …”
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TDP-43 nuclear retention is antagonized by hypo-phosphorylation of its C-terminus in the cytoplasm by Célia Rabhi, Nicolas Babault, Céline Martin, Bénédicte Desforges, Alexandre Maucuer, Vandana Joshi, Serhii Pankivskyi, Yitian Feng, Guillaume Bollot, Revital Rattenbach, David Pastré, Ahmed Bouhss

“…Importantly, we have analyzed specifically the self-assembly of full-length TDP-43 and its mRNA binding that are regulated by the phosphorylation of its self-adhesive C-terminus, which is the recipient of many pathological mutations. We show that C-terminus phosphorylation prevents the recruitment of TDP-43 in mRNA-rich stress granules only under acute stress conditions because of a low affinity for mRNA but not under mild stress conditions. …”
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The Agreement Rate between Radiographic Interpretation and Histopathologic Diagnosis of Jaw Lesions by Soulafa Almazrooa, Nada O. Binmadi, Hanadi M. Khalifa, Fatima M. Jadu, Ahmed M. Jan, Dalia E. Meisha

“…Methods. Cases with jaw pathologies that have diagnostically adequate histopathologic samples and radiographic examinations were reviewed retrospectively. …”
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Mucoepidermoid Carcinoma of the Lung: A Case Report and Literature Review by S. Alsidawi, J. C. Morris, K. A. Wikenheiser-Brokamp, S. L. Starnes, N. A. Karim

“…Bronchoscopy, surgical resection, and pathological examination revealed a low-grade MEC with tumor-free margins. …”
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Ventricular Habronemiasis in Aviary Passerines by Jennifer N. Niemuth, Joni V. Allgood, James R. Flowers, Ryan S. De Voe, Brigid V. Troan

“…Koilin fragmentation with secondary bacterial and fungal infections was the most frequently observed pathologic lesion. Secondary visceral amyloidosis, attributed to chronic inflammation associated with nematodiasis, was present in 4 individuals. …”
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An Unusual Cause of Abdominal Pain: Three Lead Pellets within the Appendix Vermiformis by Orhan Veli Ozkan, Vecdi Muderris, Fatih Altintoprak, Orhan Yagmurkaya, Omer Yalkin, Fehmi Celebi

“…An appendectomy was performed. Pathologically, three lead pellets were embedded in the appendix, which showed signs of intramucosal inflammation. …”
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Role of Lactate in Inflammatory Processes: Friend or Foe by Carolina Manosalva, John Quiroga, John Quiroga, Alejandra I. Hidalgo, Pablo Alarcón, Nicolás Ansoleaga, Nicolás Ansoleaga, María Angélica Hidalgo, Rafael Agustín Burgos

“…Taken together, the evidence suggests that lactate could exert differential effects depending on the metabolic status, cell type in which the effects of lactate are studied, and the pathological process analyzed. Additionally, various targets, including post-translational modifications, G-protein coupled receptor and transcription factor activation such as NF-κB and HIF-1, allow lactate to modulate signaling pathways that control the expression of cytokines, chemokines, adhesion molecules, and several enzymes associated with immune response and metabolism. …”
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Mechanism and Design Analysis of Articulated Ankle Foot Orthoses for Drop-Foot by Morshed Alam, Imtiaz Ahmed Choudhury, Azuddin Bin Mamat

“…Individuals suffering from stroke and other neurological disorders often experience inadequate dorsiflexion during swing phase of the gait cycle due to dorsiflexor muscle weakness. This type of pathological gait, mostly known as drop-foot gait, has two major complications, foot-slap during loading response and toe-drag during swing. …”
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The management of body dysmorphic disorder in adolescents: A systematic literature review by Ghosh Tania, Blair Erik

“…Body dysmorphic disorder (BDD) is a pathological body dissatisfaction characterised by delusional beliefs of a flaw in appearance paired with obsessive-compulsive rituals. …”
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Multiple Gastric Erosion Early after a 3 V Lithium Battery (CR2025) Ingestion in an 18-Month-Old Male Patient: Consideration about the Proper Time of Intervention by Ioannis Patoulias, Christos Kaselas, Dimitrios Patoulias, Konstantinos Farmakis, Eleni Papacrivou, Maria Kalogirou, Thomas Feidantsis

“…He did not have any symptoms and no pathological findings were encountered during clinical examination. …”
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