A Framework for the Objective Assessment of Registration Accuracy by Francesca Pizzorni Ferrarese, Flavio Simonetti, Roberto Israel Foroni, Gloria Menegaz

“…Results revealed a higher correlation and a lower dispersion among the metrics for simulated data, while the opposite trend was observed for pathologic ones. Results show that the proposed model not only provides a good prediction performance but also leads to the optimization of the end-to-end chain in terms of accuracy and robustness, setting the ground for its generalization to different and more complex scenarios.…”
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COph100: A comprehensive fundus image registration dataset from infants constituting the “RIDIRP” database by Yan Hu, Mingdao Gong, Zhongxi Qiu, Jiabao Liu, Hongli Shen, Mingzhen Yuan, Xiaoqing Zhang, Heng Li, Hai Lu, Jiang Liu

“…Existing public datasets, focusing on adult retinal pathologies with high-quality images, have limited number of image pairs and neglect clinical challenges. …”
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Probiotics in the Modern World by Y. P. Uspenskiy, Y. A. Fominykh, K. N. Nadzhafova, S. V. Polyushkin

“…The review highlights modern concepts of the role of microbiome in sustaining the human body, the place of probiotics in treatment and prevention of pathologies related to disorders in healthy microbiota.Key points. …”
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Сryosurgery possibilities for nevus in intermarginal eyelid space by A.N. Steblyuk, V.E. Gunter, S.N. Sahnov, P.A. Khloponin, Е.V. Bykova, Zh.G. Litvinova

“…Depending on the size of the pathological formation, exposure duration, the frequency of application repetitions per session, the nevus regression occurred within 1.5–2.0 months with preserving the integrity of the eyelid intermarginal space and the eye functional condition. …”
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Role of Inflammation in Muscle Homeostasis and Myogenesis by Domiziana Costamagna, Paola Costelli, Maurilio Sampaolesi, Fabio Penna

“…Muscle wasting, characteristic of several pathological states associated with local or systemic inflammation, has been for long considered to rely on the alteration of myofiber intracellular pathways regulated by both hormones and cytokines, eventually leading to impaired anabolism and increased protein breakdown. …”
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CLINICAL AND RADIOLOGICAL PARAMETERS IN MALIGNANT SPINAL TUMORS: A DESCRIPTIVE ANALYSIS by Marcelo Diniz de Menezes, Mariana Demétrio de Sousa Pontes, Carlos Fernando Pereira da Silva Herrero

“…The radiological evaluation analyzed radiographic exams, computed tomographies, and MRIs, focusing on morpho-pathological characteristics and the treatments employed. …”
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Comprehensive multi-omics, behavioral and morphological analysis of the hazards of nano-plastics in mice with internal carotid artery occlusion by Lu Wang, Jia-Qi Ma, Li-Jia Song, Xiao-Peng Qu, Yue Zhang, Hai-Ming Fan, Chao Wang, Long-Long Zheng, Guo-Dong Gao, Yan Qu, Liang-Liang Shen, Bei Liu

“…The NPs not only accumulated in the brain and caused pathologic damage, but also contributed to accelerating atherosclerosis in the mouse model of internal carotid artery occlusion. …”
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Endocan in Cancers: A Lesson from a Circulating Dermatan Sulfate Proteoglycan by Maryse Delehedde, Lucie Devenyns, Claude-Alain Maurage, Romain R. Vivès

“…Consequently, Endocan expression has been associated with a growing number of pathological conditions where endothelium gets challenged and notably in highly vascularized cancers. …”
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Obese hypoventilation syndrome. Presentation of a case by Luis Virgilio Díaz Martìnez, Yenisel Chang Cuesta, Inti Santana Carballosa

“…The case of a 53-years-old patient, white skin color, male, from urban origin, with a personal pathological history of high blood pressure, gouty arthritis, morbid obesity, unstable angina pectoris, previous episodes of atrial fibrillation and Pickwick syndrome without treatment for it, it is presented. …”
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Regulatory T Cells in Autoimmune and Viral Chronic Hepatitis by Pascal Lapierre, Alain Lamarre

“…This tolerance mechanism is carefully regulated in physiological conditions but any imbalance could be pathological. An overly tolerant immune response can lead to chronic infections while an overreactive and unbridled immune response can lead to autoimmune hepatitis. …”
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An Improved Yolov10n for Detection of Bronchoalveolar Lavage Cells by Peihe Jiang, Shaoqi Li, Yanfen Lu, Xiaogang Song

“…These components provide a non-invasive method to obtain pathological information about the lungs, serving as a powerful complement to traditional lung biopsies. …”
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Association between microplastics and the functionalities of human gut microbiome by Bei Gao, Lixia Chen, Lizhi Wu, Shirui Zhang, Sunan Zhao, Zhe Mo, Zhijian Chen, Pengcheng Tu

“…As an integral part of humans, the gut microbiome plays a significant role in the physiological and pathological processes of the host, and dysbiosis of the gut microbiome is linked to various diseases. …”
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CARDIOVASCULAR RISK IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE by L.I. Konopkina, L.A. Botvinikova, M.A. Krykhtina

“…We observed 29 men with the severe course of COPD in stable phase of the pathological process. In order to identify the extent of total CVR, we determined the demographic parameters for each patient (age, gender), attitude to smoking (smoker / non-smoker), systolic blood pressure and total cholesterol (TC) levels (mmol/l). …”
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Musculoskeletal Ultrasound: An Essential Tool in Diagnosing Patellar Tendon Injuries by Robert C. Manske, Phil Page, Michael Voight, Chris Wolfe

“…It allows for accurate visualization of the patellar tendon's structure and function, thereby facilitating the identification of pathological changes such as thickening, thinning, or disruption which aids in diagnosing conditions such as tendonitis, partial tears, and ruptures. …”
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The Dynamicity of the Oxytocin Receptor in the Brain May Trigger Sensory Deficits in Autism Spectrum Disorder by Claudia Camerino

“…Activation of the Oxt system through exposure to cold stress regulates the expression of oxytocin receptor (Oxtr) in the brain and circulating Oxt, and if this mechanism is pathologically disrupted, it can lead to sensory processing abnormalities since Oxt acts as a master gene that regulates thermogenesis. …”
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From Mild Ataxia to Huntington Disease Phenocopy: The Multiple Faces of Spinocerebellar Ataxia 17 by Georgios Koutsis, Marios Panas, George P. Paraskevas, Anastasia M. Bougea, Athina Kladi, Georgia Karadima, Elisabeth Kapaki

“…We presently report a Greek family with a pathological expansion of 54 repeats at the SCA 17 locus that displayed remarkable phenotypic variability. …”
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Oxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases? by Stefania Gonfloni, Emiliano Maiani, Claudia Di Bartolomeo, Marc Diederich, Gianni Cesareni

“…In line with these observations, an increased c-Abl activation is reported in human neurodegenerative pathologies, such as Parkinson’s, and Alzheimer’s diseases. …”
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Effect of Hemoadsorption for Cytokine Removal in Pneumococcal and Meningococcal Sepsis by Francesca Leonardis, Viviana De Angelis, Francesca Frisardi, Chiara Pietrafitta, Ivano Riva, Tino Martino Valetti, Valentina Broletti, Gianmariano Marchesi, Lorenza Menato, Roberto Nani, Franco Marson, Mirca Fabbris, Luca Cabrini, Sergio Colombo, Alberto Zangrillo, Carlo Coniglio, Giovanni Gordini, Lucia Stalteri, Giovanni Giuliani, Vittorio Dalmastri, Gaetano La Manna

“…We herein report five patients with similar critical pathological conditions, characterized by pneumococcal or meningococcal sepsis and treated with hemoadsorption for cytokine removal. …”
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Connection between oral health and chronic diseases by Di Fu, Xingyue Shu, Ge Zhou, Mengzhen Ji, Ga Liao, Ling Zou

“…Neglecting oral health can exacerbate localized pathologies and accelerate the progression of chronic conditions, whereas effective management has the potential to reduce their incidence and mortality. …”
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Breakage of a Third Generation Gamma Nail: A Case Report and Review of the Literature by Takashi Iwakura, Takahiro Niikura, Sang Yang Lee, Yoshitada Sakai, Kotaro Nishida, Ryosuke Kuroda, Masahiro Kurosaka

“…We present the first reported case of breakage of a third generation Gamma nail that was not used to treat a pathological fracture. An 83-year-old woman with an unstable trochanteric fracture of the femur was treated using a third generation Gamma nail. …”
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