MicroRNA as a Potential Biomarker and Treatment Strategy for Ischemia-Reperfusion Injury by Mingming Cao, Wenjing Song, Runyu Liang, Lili Teng, Mei Zhang, Jiyao Zhang, Luwen Zhu

“…Ischemia-reperfusion (I/R) injury is a progressive injury that aggravates the pathological state when the organ tissue restores blood supply after a certain period of ischemia, including the myocardial, brain, liver, kidney, and intestinal. …”
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BIOMARKERS, NEOANGIOGENESIS AND GROWTH FACTORS IN PANCREATIC CANCER by E. M. Frantsiyants, O. I. Kit, V. I. Aleynov, I. A. Goroshinskaya

“…Angiogenesis has been identified as a key factor in a number of pathological conditions, including cancer. The proangiogenic signaling molecule – vascular endothelial growth factor (VEGF) and its receptors play a central role in tumor angiogenesis. …”
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Possible Involvement of Liver Resident Macrophages (Kupffer Cells) in the Pathogenesis of Both Intrahepatic and Extrahepatic Inflammation by Yuki Kakinuma, Takuya Kimura, Yoshifumi Watanabe

“…Administration of clodronate liposomes resulted in the KC deletion and in the suppression of liver injury in T cell-mediated hepatitis by ConA as a local acute inflammation model, while the treatment did not influence dextran sulfate sodium- (DSS-) induced colitis featured by weight loss, intestinal shrink, and pathological observation as an ectopic local acute inflammation model. …”
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Culture of Critical Discourse on Education and Science by M. B. Sapunov, Kh. G. Tkhagapsoev

“…The authors state the change of the critique vector – the transition from value-loaded political statements to scientific analysis of the objective factors determining social pathologies in education system. The situation today is characterized by the attempts to find and formulate an objectivated language to describe social reality. …”
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Mesenchymal Stem Cells (MSCs): A Novel Therapy for Type 2 Diabetes by Shuang Gao, Yuanyuan Zhang, Kaini Liang, Ran Bi, Yanan Du

“…Potential mechanisms of MSC-based intervention on multiple pathological processes of T2DM, such as β-cell exhaustion, hepatic dysfunction, insulin resistance, and systemic inflammation, are also delineated. …”
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A Case of Brucellosis Presenting with Multiple Hypodense Splenic Lesions and Bilateral Pleural Effusions by Emine Dilek Eruz, Serhat Birengel, Alpay Azap, Gulden Yilmaz Bozkurt

“…Brucellosis was expected to be the cause of all pathological signs.…”
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MicroRNAs in the DNA Damage/Repair Network and Cancer by Alessandra Tessitore, Germana Cicciarelli, Filippo Del Vecchio, Agata Gaggiano, Daniela Verzella, Mariafausta Fischietti, Davide Vecchiotti, Daria Capece, Francesca Zazzeroni, Edoardo Alesse

“…Due to their activity, microRNAs play a role in many fundamental physiological and pathological processes. In this review we report and discuss the role of microRNAs in the DNA damage/repair and cancer.…”
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Bilateral Choroidal Metastases as Presentation of Dissemination of Cutaneous Malignant Melanoma by S. Fernandez-Perez, O. Ruiz-Moreno, V. Pueyo, G. de la Mata, L. Pablo

“…The patient obtained clinical ocular improvement after palliative chemotherapy, although he died in the following months. Pathological examination of the lesions confirmed the diagnosis of choroidal metastases from a malignant cutaneous melanoma. …”
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Designing and developing a prescription digital therapeutic for at-home heart rate variability biofeedback to support and enhance patient outcomes in post-traumatic stress disorder... by Rebecca Macy, Flavio Somanji, Flavio Somanji, Oleksandr Sverdlov

“…While various forms of psychotherapy are commonly utilized in PTSD treatment, the known neurological pathologies associated with PTSD are insufficiently addressed by these conventional approaches. …”
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Eating Disorders and Intrasexual Competition: Testing an Evolutionary Hypothesis among Young Women by Riadh Abed, Sunil Mehta, Aurelio José Figueredo, Sarah Aldridge, Hannah Balson, Caroline Meyer, Robert Palmer

“…It argues that eating disorders are pathological phenomena that arise from the mismatch between the modern environment and the inherited female adaptations for ISC. …”
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Combined Effect of Lentinan and Cisplatin on Cytokines IL-6, TNF-α, and TGF-β in Tumor Therapy by Xu-dong Liu, Min Li, Wan-xiang Li, Qing-yu Wang, Hong-xia Zhang

“…Cytokines, at the same time, are a key factor in regulating immune responses in physiological and pathological states. Many cytokines have shown positive effect on different malignancies in clinical trials. …”
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Androgen Receptor Regulates Transcription of the ZEB1 Transcription Factor by Bynthia M. Anose, Michel M. Sanders

“…The zinc finger E-box binding protein 1 (ZEB1) transcription factor belongs to a two-member family of zinc-finger homeodomain proteins involved in physiological and pathological events mostly relating to cell migration and epithelial to mesenchymal transitions (EMTs). …”
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Polymeric Scaffolds in Tissue Engineering Application: A Review by Brahatheeswaran Dhandayuthapani, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar

“…Current strategies of regenerative medicine are focused on the restoration of pathologically altered tissue architectures by transplantation of cells in combination with supportive scaffolds and biomolecules. …”
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Canadian Helicobacter Study Group Consensus Conference on the Approach to Helicobacter Pylori Infection in Children and Adolescents by P Sherman, E Hassall, RH Hunt, CA Fallone, S Veldhuyzen van Zanten, ABR Thomson, Canadian Helicobacter Study Group

“…Gastric infection with Helicobacter pylori is common in both children and adults, but children are considerably less susceptible to peptic ulcers and other pathological sequelae. As a result, the risk to benefit ratio of diagnostic studies and therapeutic regimens for H pylori in adults are likely different from those in paediatric populations. …”
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The Controversial C5a Receptor C5aR2: Its Role in Health and Disease by Ting Zhang, Malgorzata A. Garstka, Ke Li

“…Ramifications and controversies about C5aR2 are under debate since its identification, from putative ligands and cellular localization to intracellular signals and pathological roles in inflammation and immunity. The ruleless and even conflicting pro- or anti-inflammatory role of C5aR2 in animal models of diverse diseases makes one bewildered. …”
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Solitary fibular metastasis from lung adenocarcinoma with gene mutation: a case report by Jiechen Chen, Ahmad Alkhatatbeh, Yinbing Lin, Xiaolin Lu, Bin Chen, Hongjiang Chen, Xiaohui Lu, Hansheng Wu, Jun Hu

“…Imaging revealed bony destruction of the right fibular head, and further investigations with chest CT, PET/C, pathologic biopsy and genetic testing identified a primary lung adenocarcinoma with EGFR exon 19 deletion mutation. …”
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Sirtuin 1: A Dilemma in Transplantation by Sara Assadiasl, Nuala Mooney, Bahareh Mohebbi, Yousef Fatahi, Narjes Soleimanifar

“…Sirtuin 1, a member of sirtuin family of histone deacetylase enzymes, has been implicated in a variety of physiologic and pathologic events, including energy metabolism, cell survival, and age-related alterations. …”
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The Role of Sialic Acid-Binding Receptors (Siglecs) in the Immunomodulatory Effects of Trypanosoma cruzi Sialoglycoproteins on the Protective Immunity of the Host by Alexandre Morrot

“…Mucins are high molecular weight glycoproteins that are involved in regulating diverse cellular activities in both normal and pathological conditions. In Trypanosoma cruzi infection, the parasite-derived mucins are the main acceptors of sialic acid and it has been suggested that they play a role in various host-parasite interactions during the course of Chagas disease. …”
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Hirsutism Caused by Pregnancy Luteoma in a Low-Resource Setting: A Case Report and Literature Review by David Hamisi Mvunta, Fatemazahra Amiji, Mubina Suleiman, Francisco Baraka, Ikrah Abdallah, Mabula Kazabula, Peter J. T. Wangwe, Furaha August

“…Intraoperatively, a huge left ovarian mass was identified and resected, and tissue was sent for histopathology and a diagnosis of pregnancy luteoma was made after the pathological report. Conclusion. The present report emphasizes that pregnancy luteoma is a benign neoplasm and imprudent surgical intervention should be reserved. …”
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Navigational Bronchoscopy with Cryobiopsy for Diagnosis of ILD by Fernando Figueroa Rodriguez, Asfar Ghauri, Tony Abdo, Salim Daouk, Shideler Barbara, Houssein A. Youness

“…Interstitial lung diseases (ILDs) are a group of parenchymal pulmonary diseases in which pathologic diagnosis is essential. Although cryobiopsy has a high diagnostic yield, the complication rate remains high. …”
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