Uptake of Non-Transferrin Iron by Erythroid Cells by Eugenia Prus, Eitan Fibach

“…Most of the iron in the plasma is bound to transferrin (Tf) and is taken up by cells through their surface Tf receptors (TfRs). Under pathological conditions of iron-overload, the plasma iron which is in excess of the binding capacity of Tf is present as non-Tf-bound iron. …”
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Non-histone lactylation: unveiling its functional significance by Pusong Shi, Yongjie Ma, Yongjie Ma, Yongjie Ma, Yongjie Ma, Yongjie Ma, Shaolu Zhang, Shaolu Zhang, Shaolu Zhang, Shaolu Zhang, Shaolu Zhang

“…Indeed, lactylation is implicated in various physiological and pathological processes, including tumor development, cardiovascular and cerebrovascular diseases, immune cell activation and psychiatric disorders. …”
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Apoptosis-Inducing Factor, Protein Expression, and Apoptosis Changes with Glutamine in Podocytes Cells Exposed with Cisplatin by Imam Susilo, Himmayatussorofil Maulida, Lindawati Alimsardjono, Dyah Fauziah, Herinda Pertiwi

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Efficacy and safety of perioperative sintilimab plus platinum-based chemotherapy for potentially resectable stage IIIB non-small cell lung cancer (periSCOPE): an open-label, single... by Xiangyang Yu, Chujian Huang, Longde Du, Chunguang Wang, Yikun Yang, Xin Yu, Shengcheng Lin, Chenglin Yang, Hongbo Zhao, Songhua Cai, Zhe Wang, Lixu Wang, Xiaotong Guo, Baihua Zhang, Zhentao Yu, Jie He, Kai Ma

“…The primary endpoint was major pathological response (MPR). The key secondary endpoints included the objective response rate (ORR), radical resection (R0) rate, pathological complete response (pCR) rate, event-free survival (EFS), disease-free survival (DFS), OS, treatment-related adverse events (TRAEs), surgical complications, and surgery delay rate. …”
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Options of improvement of efficacy of gastroesophageal reflux disease treatment by dioctaedric smectite by O. A. Storonova, A. S. Trukhmanov, N. Yu. Ivashkina, V. T. Ivashkin

“…To analyze efficacy of heartburn relief and pathological gastroesophageal reflux (GER) elimination as well as dynamics of endoscopic changes at gastroesophageal reflux disease (GERD) under dioctaedric smectite (Smecta) treatment in standard doze as monotherapy and within complex mode of treatment.Material and methods. …”
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Anterior Controllable Antedisplacement and Fusion (ACAF) for Cervical Stenosis Patients With Hyperextension Injury: A Retrospective Study by Shuangxi Sun, Yingying Miao, Tao Xu, Kaiqiang Sun, Yijuan Lu, Jingchuan Sun, Jiuyi Sun, Jiangang Shi

“…The radiological parameters included associated pathologies, prevertebral hyperintensity (HI), intramedullary signal intensity (ISI), and Torg–Pavlov ratio (TPR). …”
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Prognostic evaluation of non-muscle invasive bladder cancer with P-CRP and its nomogram by Junyun Wu, Zhixuan Deng, Xu Lei, Zhiyao Xu, Chenxi Tan, Yunqiao Tang, Xi Sheng, Ning Yang

“…The Nomogram incorporating P-CRP, number of tumors, tumor size, T stage, and tumor pathological grading can better predict the postoperative recurrence risk of NMIBC patients.…”
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Diagnostic Accuracy of Magnetic Resonance Imaging in the Diagnosis of Placenta Accreta Spectrum: A Systematic Review and Meta-analysis by Suzi AbdelAziz, Nour A. El-Goly, Ahmed M. Maged, Nehal Bassiouny, Nihal El-Demiry, Ahmed Shamel, Yang Pan

“…All prospective and retrospective cohort, case-control, and cross-sectional studies involving prenatal magnetic resonance imaging diagnosis of PAS with subsequent pathological confirmation were included. Results:. A total of 40 studies encompassing 3664 women met the inclusion criteria, with 1894 cases confirmed pathologically as PAS. …”
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Rationale and design of a multicentre randomised controlled trial on circulating tumour DNA-guided neoadjuvant treatment strategy for locally advanced rectal cancer (CINTS-R) by Bin Wu, Yi Xiao, Xiao Zhang, Tao Xu, Qian Liu, Wei Fu, Yang An, Yongheng Li, Guole Lin, Huadan Xue, Guoju Wu, Jiaolin Zhou, Hongwei Yao, Zhenjun Wang, Weijie Chen, Junyang Lu, Guannan Zhang, Xiaoyuan Qiu

“…The secondary endpoints include time to recurrence, 2-year overall survival, 2-year disease-free survival, clinical complete response (cCR) rate, near cCR rate and pathologically complete response rate, pathological tumour regression grade and quality of life.Ethics and dissemination This protocol has been approved by the ethics committee of Peking Union Medical College Hospital, with approval number I-23PJ157, and by the institutional review boards of all the participating centres. …”
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Breathing time: a longue-durée multidisciplinary study of respiratory illnesses and airborne diseases in Switzerland (16th–21st century CE) by Tobias Hofstetter, Aude Fauvel, Silke Grabherr, Negahnaz Moghaddam

“…This model serves as a relevant reading grid for the understanding of the pathological and demographic evolutions that this study highlights. …”
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Characteristics and multi-omics analysis of spontaneous spondyloarthritis in non-human primates: Case report by Lei Cai, Qing Lv, Ronghua Ma, Wei Liu, Yalun Guan, Zhongqiang Huang, Qingyu Liu, Yunfeng Li, Shuhua Liu, Ge Li, Yu Zhang

“…Spondyloarthritis is a prevalent and persistent condition that significantly impacts the quality of life. Its intricate pathological mechanisms have led to a scarcity of animal models capable of replicating the disease progression in humans, making it a prominent area of research interest in the field. …”
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The Mast Cell-Aryl Hydrocarbon Receptor Interplay at the Host-Microbe Interface by Claudio Costantini, Giorgia Renga, Vasilis Oikonomou, Giuseppe Paolicelli, Monica Borghi, Marilena Pariano, Antonella De Luca, Matteo Puccetti, Claudia Stincardini, Paolo Mosci, Andrea Bartoli, Teresa Zelante, Luigina Romani

“…Herein, we summarize the current knowledge about the mechanisms underlying the ability of the microorganisms to regulate mast cell physiology and discuss potential deviations that result in pathological consequences. We will discuss the pivotal role of the aryl hydrocarbon receptor in sensing the environment and shaping mast cell adaptation at the host-microbe interface.…”
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Accessible model predicts response in hormone receptor positive HER2 negative breast cancer receiving neoadjuvant chemotherapy by Luca Mastrantoni, Giovanna Garufi, Giulia Giordano, Noemi Maliziola, Elena Di Monte, Giorgia Arcuri, Valentina Frescura, Angelachiara Rotondi, Armando Orlandi, Luisa Carbognin, Antonella Palazzo, Federica Miglietta, Letizia Pontolillo, Alessandra Fabi, Lorenzo Gerratana, Sergio Pannunzio, Ida Paris, Sara Pilotto, Fabio Marazzi, Antonio Franco, Gianluca Franceschini, Maria Vittoria Dieci, Roberta Mazzeo, Fabio Puglisi, Valentina Guarneri, Michele Milella, Giovanni Scambia, Diana Giannarelli, Giampaolo Tortora, Emilio Bria

“…In patients receiving neoadjuvant chemotherapy (NACT), pathological complete response (pCR) is rare and multiple efforts have been made to predict disease recurrence. …”
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Deficiencias en la entrevista médica: Un aspecto del método clínico by Miguel Moreno Rodríguez

“…It was evident that there is a trend to obtaining information by means of brief and closed questions, inducing to responses and start by personal pathologic backgrounds, as well as serious difficulties in interrogation abilities. …”
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Chemokines in Cancer Development and Progression and Their Potential as Targeting Molecules for Cancer Treatment by Naofumi Mukaida, So-ichiro Sasaki, Tomohisa Baba

“…Subsequent studies have further revealed that chemokines can regulate the movement of a wide variety of immune cells including lymphocytes, natural killer cells, and dendritic cells in both physiological and pathological conditions. These features endow chemokines with crucial roles in immune responses. …”
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Destin des identifications dans la perte : le fantôme by Ophélie Méchin

“…Are these apparitions always pathological or are they, though frightening at times, the building blocks of this process ? …”
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Activity-Dependent NPAS4 Expression and the Regulation of Gene Programs Underlying Plasticity in the Central Nervous System by José Fernando Maya-Vetencourt

“…A better understanding of how modifications in the connectivity of neuronal networks occur may shed light on the treatment of pathological conditions such as brain damage or disease in adult life, some of which were once considered untreatable.…”
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Frequency of the Causes of Postmenopausal Bleeding, Results of a Tertiary Referral Center in Turkey by Umit Yasemin Sert, Ismail Guler, Tuncay Nas

“…The frequency of etiologic factors and relevancy of pathological results with demographic factors were determined. …”
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Osteoblastic Metastases Mimickers on Contrast Enhanced CT by Fahad Al-Lhedan, Sam Samaan, Wanzhen Zeng

“…The aim of imaging is to identify the presence and extent of osseous disease and to assess for possible complications such as pathological fracture of the load-bearing bones and cord compression if the lesion is spinal. …”
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From the ethology of animals to the human ecology by Zbigniew Łepko

“…Lorenz conducted an ethological examination of human culture, thereby uncovering its biological bases, its dynamics, social pathologies and means for overcoming them. Thanks to this Lorenz gained an insight into the character of the crisis of contemporary civilization, described and diagnosed it, presented the causes and proposed a cure. …”
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