Does Branched-Chain Amino Acids Supplementation Modulate Skeletal Muscle Remodeling through Inflammation Modulation? Possible Mechanisms of Action by Humberto Nicastro, Claudia Ribeiro da Luz, Daniela Fojo Seixas Chaves, Luiz Roberto Grassmann Bechara, Vanessa Azevedo Voltarelli, Marcelo Macedo Rogero, Antonio Herbert Lancha

“…The proinflammatory status of muscle cells, observed in pathological conditions such as cancer, aging, and sepsis, can directly modulate protein translation initiation and muscle proteolysis, contributing to negative protein turnover. …”
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Hypopigmented Mycosis Fungoides in an 11-Year-Old Palestinian Boy by Duha Rabi, Balqis Shawer, Ahmad Rabee, Mohammad Qudaimat, Mohammad Milhem, Izzeddin Bakri

“…Misdiagnosis of MF can occur because it may resemble other benign skin pathologies. This is a case of an 11-year-old Palestinian boy presented with generalized nonpruritic hypopigmented maculopapular patches with progressive course for 9-months. …”
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Recent advances in the role of high-salt diet in anti- and pro-cancer progression by Shiwei Tang, Juan Xu, Ping Wan, Ping Wan, Ping Wan, Shumen Jin, Ying Zhang, Ying Zhang, Linting Xun, Linting Xun, Jinli Wang, Jinli Wang, Mei Luo, Mei Luo, Wenjie Chen, Wenjie Chen, Zan Zuo, Zan Zuo, Zan Zuo, Hui Tang, Hui Tang, Jialong Qi, Jialong Qi, Jialong Qi, Jialong Qi, Jialong Qi

“…However, recent studies have uncovered a novel aspect of HSD, suggesting that HSD may inhibit tumor growth in specific pathological conditions by modulating the activity of immune cells that infiltrate tumors and enhancing the effectiveness of PD-1 immunotherapy. …”
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Role of dietary and nutritional interventions in ceramide-associated diseases by Shengnan Wang, Zihui Jin, Biyu Wu, Andrew J. Morris, Pan Deng

“…Elevated cellular and circulating ceramide levels are consistently associated with pathological conditions including cardiometabolic diseases, neurological diseases, autoimmune diseases, and cancers. …”
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Umbilical Cord Mesenchymal Stromal Cells for Cartilage Regeneration Applications by E. Russo, M. Caprnda, P. Kruzliak, P. G. Conaldi, C. V. Borlongan, G. La Rocca

“…Mesenchymal stromal cell (MSCs) transplantation represents a promising approach to counteract the degenerative and inflammatory environment characterizing those pathologies, such as osteoarthritis (OA) and rheumatoid arthritis (RA). …”
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Airway Remodelling in Asthma and COPD: Findings, Similarities, and Differences Using Quantitative CT by Gaël Dournes, François Laurent

“…The structural changes found on pathological examination of remodelled airway wall have been shown to display similarities but also differences. …”
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New-onset seizure in pregnancy: case report and literature review by I. Paulauskienė, R. Mameniškienė

“…This article presents a clinical case of a 31-year-old primigravida woman at 29 weeks of gestation diagnosed with new-onset epilepsy which manifested with bilateral tonic-clonic seizure and slow pathological waves on the EEG with no neurologic deficits or magnetic resonance imaging abnormalities. …”
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Deciphering the mechanisms of long non-coding RNAs in ferroptosis: insights into its clinical significance in cancer progression and immunology by Shengming Ou, Xiaoya Nie, Xiangyu Qiu, Xin Jin, Geyan Wu, Rongxin Zhang, Jinrong Zhu

“…Abstract A new type of nonapoptotic, iron-dependent cell death induced by lipid peroxidation is known as ferroptosis. Numerous pathological processes, including inflammation and cancer, have been demonstrated to be influenced by changes in the ferroptosis-regulating network. …”
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Non-diffuse Large B-cell Lymphoma. Case Presentation by Miguel Ángel Serra Valdés, Yasniel Borrego Moreno, Marleny Viera García

“…The case of a 64-year-old patient is presented, with a pathological history of arterial hypertension, ex-smoker, who was admitted because for 3 months she had increased volume of the left lateral region of the neck. …”
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Altered Gene Expression, Mitochondrial Damage and Oxidative Stress: Converging Routes in Motor Neuron Degeneration by Luisa Rossi, Cristiana Valle, Maria Teresa Carrì

“…This is particularly well demonstrated in ALS, where both sporadic and familial forms share the same symptoms and pathological phenotype, with a prominent role for mitochondrial damage and resulting oxidative stress. …”
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Spontaneous rupture of a giant mature teratoma in the lateral ventricle: a case report by Yong Xiao, Liang Liu, Ran Wang, Dong Wang, Liangyuan Geng, Xinhua Hu, Yong Liu, Chunfa Qian, Yuanjie Zou

“…The patient underwent gross total resection of the tumor, and the subsequent pathological examination confirmed the diagnosis of mature teratoma. …”
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Alcoholism and Inflammatory Response: Implications for Liver and Cardiovascular Disease by Christian Gabriel Acosta Ricachi, Sheila Ivette Quinapanta Serrano, Álvaro Paúl Moina Veloz

“…A synthesis based on scientific evidence was carried out, which will provide medical professionals with updated knowledge on the pathological and physiological consequences of long-term alcohol consumption.…”
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The Effects of Hypoxia on the Immune-Modulatory Properties of Bone Marrow-Derived Mesenchymal Stromal Cells by Zsolt Fábián

“…Since one of the typical features of inflamed tissues is decreased oxygenation, the success of cellular therapy in inflammatory pathologies seems to be affected by the impact of oxygen depletion on transplanted cells. …”
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Neutrophils in Tuberculosis: Heterogeneity Shapes the Way? by Irina V. Lyadova

“…This review analyzes data on neutrophil defensive and pathological functions during tuberculosis and considers hypotheses explaining the dualism of neutrophils during M. tuberculosis infection and tuberculosis disease.…”
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THE ROLE OF COMPUTED TOMOGRAPHY IN THE DIAGNOSIS OF RETROPERITONEAL FIBROSIS by A. O. Rudnev, M. N. Maxim, V. B. Vizhgorodsky, A. V. Kiryushin, S. Yu. Kotans

“…Although the final diagnosis can be made only on the basis of biopsy, computed tomography is of great importance for the evaluation of the pathological process, it allows diagnosing the disease, assessing its prevalence and observing the dynamics during treatment. …”
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Risk Assessment of BRONJ in Oncologic Patients Treated with Bisphosphonates: Follow-Up to 18 Months by Scilla Sparabombe, Lucia Vitali, Alessandra Nori, Ricarda Sara Berlin, Marta Mazur, Giovanna Orsini, Angelo Putignano

“…Bisphosphonates related osteonecrosis of the jaw (BRONJ) is a pathological condition characterized by bone exposure or latent infection in patients treated with the drug. …”
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The Regulation and Functions of Endogenous Retrovirus in Embryo Development and Stem Cell Differentiation by Yangquan Xiang, Hongqing Liang

“…During the course of life, ERVs are associated with multiple aspects of chromatin and transcriptional regulation in development and pathological conditions. In mammalian embryos, ERVs are extensively activated in early embryo development, but with a highly restricted spatial-temporal pattern; and they are drastically silenced during differentiation with exceptions in extraembryonic tissue and germlines. …”
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Factors Contributing to Diagnosis and Prognosis in Sinonasal Malignancies by Wenjing Li, Jianqiang You, Haixiang Xue, Changjiang Chao

“…Cox regression model was used for multivariate analysis. Results. Gender, pathological type, treatment plan, clinical stage, and survival time of patients were different. …”
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Cerebellar Development and Plasticity: Perspectives for Motor Coordination Strategies, for Motor Skills, and for Therapy by J. D. Swinny, J. J. L. van der Want, A. Gramsbergen

“…This understanding will also help in the approach to possible therapies of pathologies arising during development because tile cerebellum is especially prone to such perturbation because of its late development.…”
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Molecular Mechanisms of Oxytocin Signaling at the Synaptic Connection by Jan Bakos, Annamaria Srancikova, Tomas Havranek, Zuzana Bacova

“…An early alteration in oxytocin signaling may disturb neuronal maturation and may have short-term and long-term pathological consequences. At the molecular level, neurodevelopmental disorders include alterations in cytoskeletal rearrangement and neuritogenesis resulting in a diversity of synaptopathies. …”
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