Targeting Chondrocyte Hypertrophy as Strategies for the Treatment of Osteoarthritis by Da-Long Dong, Guang-Zhen Jin

“…However, in the progression of OA, chondrocyte hypertrophy becomes one of its key pathological features. Although there is no definitive evidence to date confirming that chondrocyte hypertrophy is the direct cause of OA, substantial experimental data indicate that it plays an important role in the disease’s pathogenesis. …”
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Celiac Disease Assocaited with Primary Biliary Cirrhosis in a Coast Salish Native by Hugh J Freeman

“…A 41-year-old Coast Salish female was initially diagnosed with typical features of classical adult celiac disease. Clinical and pathological features of primary biliary cirrhosis were also present, along with a familial history of insulin-dependent diabetes. …”
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Roles of the Chemokine System in Development of Obesity, Insulin Resistance, and Cardiovascular Disease by Longbiao Yao, Oana Herlea-Pana, Janet Heuser-Baker, Yitong Chen, Jana Barlic-Dicen

“…In this review, we focus on and discuss members of the chemokine system for which there is clear evidence of participation in the development of obesity and obesity-induced pathologies.…”
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Management of Inflammatory Internal Root Resorption with Biodentine and Thermoplasticised Gutta-Percha by Girish Umashetty, Upendra Hoshing, Suvarna Patil, Nishant Ajgaonkar

“…This condition demands a comprehensive understanding of the pathologic process, so as to identify the cause and arrest the resorptive phenomena. …”
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MicroRNAs in Cerebral Ischemia by Yang Wang, Yongting Wang, Guo-Yuan Yang

“…Current studies found that microRNAs (miRNAs or miRs) are also closely related to the pathological process of stroke. miRNAs are a group of short, noncoding RNA molecules playing important role in posttranscriptional regulation of gene expression and they have emerged as regulators of ischemic preconditioning and ischemic postconditioning. …”
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The First Report of an Intraperitoneal Free-Floating Mass (an Autoamputated Ovary) Causing an Acute Abdomen in a Child by Ibrahim Uygun, Bahattin Aydogdu, Mehmet Hanifi Okur, Selcuk Otcu

“…A calcified mass was found floating in the abdomen and was removed. The pathological examination showed necrotic tissue debris with calcifications. …”
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Mechanisms of Alcohol-Induced Endoplasmic Reticulum Stress and Organ Injuries by Cheng Ji

“…Excessive alcohol consumption induces numerous pathological stress responses, part of which is endoplasmic reticulum (ER) stress response. …”
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A Survey of Strategies to Modulate the Bone Morphogenetic Protein Signaling Pathway: Current and Future Perspectives by Jonathan W. Lowery, Brice Brookshire, Vicki Rosen

“…Appropriate regulation of canonical BMP signaling is critical for the development and homeostasis of numerous human organ systems, as aberrations in the BMP pathway or its regulation are increasingly associated with diverse human pathologies. In this review, we provide a wide-perspective on strategies that increase or decrease BMP signaling. …”
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Ozone as Janus: this controversial gas can be either toxic or medically useful by Velio Bocci

“…The unbelievable versatility of ozone therapy is due to the cascade of ozone-derived compounds able to act on several targets leading to a multifactorial correction of a pathological state. During the past decade, contrary to all expectations, it has been demonstrated that the judicious application of ozone in chronic infectious diseases, vasculopathies, orthopedics and even dentistry has yielded such striking results that it is deplorable that the medical establishment continues to ignore ozone therapy.…”
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Mitochondrial Acetylation and Diseases of Aging by Gregory R. Wagner, R. Mark Payne

“…Although seminal discoveries have been made in the basic biology of mitochondrial acetylation, an understanding of how acetylation states influence enzyme function and metabolic reprogramming during pathological states remains largely unknown. This paper will examine our current understanding of eukaryotic acetate metabolism and present recent findings in the field of mitochondrial acetylation biology. …”
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Using wavelet denoising and mathematical morphology in the segmentation technique applied to blood cells images by Macarena Boix, Begoña Cantó

“…We study different wavelet families and we conclude that the wavelet db1 is the best and it can serve for posterior works on blood pathologies. The proposed method generatesgoods results when it is applied on several images. …”
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A Review on JC Virus Infection in Kidney Transplant Recipients by Serena Delbue, Mariano Ferraresso, Luciana Ghio, Camilla Carloni, Silvia Carluccio, Mirco Belingheri, Alberto Edefonti, Pasquale Ferrante

“…Here we describe the biology of JCV and its pathological features and we review the literature regarding the JCV infection analyzed in the setting of transplantations.…”
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Endoscopic Fistulotomy – ‘The Suprapapillary Punch’: A Method of Access to the Bile Duct during ERCP by Noel B Hershfield

“…On rare occasions, the papilla cannot be entered because of anatomical or pathological abnormalities. This report describes endoscopic fistulotomy or the suprapapillary punch that has been carried out at the Foothills Hospital in Calgary, Alberta, on 30 of 623 patients referred for ERCP for conditions causing obstruction of the common bile duct or suspected obstruction of the common bile duct. …”
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ER-Mitochondria Crosstalk during Cerebral Ischemia: Molecular Chaperones and ER-Mitochondrial Calcium Transfer by Yi-Bing Ouyang, Rona G. Giffard

“…The physical association between the endoplasmic reticulum (ER) and mitochondria, known as the mitochondria-associated ER membrane (MAM), enables highly efficient transmission of Ca2+ from the ER to mitochondria under both physiological and pathological conditions. Molecular chaperones are well known for their protective effects during cerebral ischemia. …”
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Clinical Effect of the Treatment of Lumbar Intervertebral Disc Protrusion by Yehui Zhou, Ming Yang

“…On the basis of fully eliminating the pathological factors, the intervertebral disc is reset by mechanical treatment, which makes the patient more likely to heal. …”
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Roles of core fucosylation modification in immune system and diseases by Qiu Pan, Xiao-Lian Zhang

“…Research over the past three decades has revealed the critical role of FUT8-mediated core fucosylation modification in various physiological and pathological processes, including cell growth, adhesion, receptor activation, antibody-dependent cellular cytotoxicity (ADCC), tumor metastasis and infections. …”
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Retrospective Analysis of Bone Metabolism in Patients on Waiting List for Simultaneous Pancreas-Kidney Transplantation by Simona Kratochvílová, Jana Brunová, Petr Wohl, Věra Lánská, František Saudek

“…Posttransplant osteoporosis, which evolves from preexisting bone pathologies, represents a serious complication with deteriorating consequences. …”
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Protective role of ginsenoside Rg1 in the dynamic progression of liver injury to fibrosis: a preclinical meta-analysis by Lijuan Dan, Xiuyan Li, Shuanglan Chen, Xiaojie You, Dong Wang, Tianyuan Wang, Jia Li, Wenping Liu, Jie Mu, Quansheng Feng, Quansheng Feng

“…BackgroundThe pathological progression from liver injury to fibrosis is a hallmark of liver disease, with no effective strategies to halt this transition. …”
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Establishment of a Risk Prediction Model for Pulmonary Infection in Patients with Advanced Cancer by Liangliang Yang, Xiaolong Xu, Qingquan Liu

“…Demographics, whether the primary cancer was lung cancer, lung metastasis, the pathological classification of lung cancer patients, the number of metastases, history of surgery, history of chemotherapy, history of radiotherapy, history of central venous catheterization, history of hypertension, diabetes, and whether with myelosuppression were recorded. …”
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Médecines créoles guyanaise et haïtienne face au Covid-19 by Marc-Alexandre Tareau, Guillaume Odonne

“…Indeed, on the basis of a symptomatological analogy, this disease was quickly assimilated in these systems to other pathologies causing high fevers. The respiratory symptoms are also perceived as qualifying, mobilizing many species traditionally used to treat these pathologies. …”
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