Emodin promotes the recovery of rheumatoid arthritis by regulating the crosstalk between macrophage subsets and synovial fibroblast subsets by Lianying Cheng, Xiaofeng Rong

“…Methods RA clinical samples from patients with different pathological processes were collected, and the correlations between the subsets of FLSs and STMs and pathological processes were analyzed via flow cytometry. …”
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Automatic assessment of nailfold capillaroscopy software: a pilot study by Olga Elżbieta Brzezińska, Krzysztof Andrzej Rychlicki-Kicior, Joanna Samanta Makowska

“…The sensitivity of the automatic tool relative to manual assessment in classification of correct vs. pathological images was 89.0%, specificity 89.4% for the training group, in validation 89.0% and 86.9% respectively. …”
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Risk Factors Associated with Breast Cancer in Women in a Health Area by Naifi Hierrezuelo Rojas, Mileidy Cordoví Hierrezuelo, Naiovis Neira Hierrezuelo

“…<br /><strong>Results:</strong> age over 60 years (OR=3.47), personal pathological history (OR=3.83), early menarche (OR=5.65), late menopause (OR=5.16), abandonment of breastfeeding (OR=6.59), smoking (OR=8.28) and obesity (OR=7.21) were associated with the appearance of breast cancer. …”
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Variation in Assessing Renal Allograft Rejection: A National Assessment of Nephrology Practice by John Peabody, Paul Billings, Czarlota Valdenor, Zach Demko, Solomon Moshkevich, David Paculdo, Mary Tran

“…Among nephrologists, practicing in settings ranging from transplant centers to community practice, we found that the clinical workup of kidney injury in posttransplant patients is highly variable and frequently deviates from evidence-based care. In cases with pathologic evidence of rejection, only 29.1% (102/350) received an appropriate, evidence-based biopsy, whereas, in cases with no pathological evidence of rejection, 41.3% (45/109) received low-value, unnecessary biopsies. …”
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Light-chain proximal tubulopathy: a retrospective study from a single Chinese nephrology referral center by Xin Wang, Xiao-juan Yu, Su-xia Wang, Fu-de Zhou, Ming-hui Zhao

“…Clinical data, kidney pathological type, treatment, and prognosis were analyzed.Results Nineteen patients were enrolled, the mean age at diagnosis was 57 ± 11 and the sex ratio was 6/13 (female/male). …”
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Context aware machine learning techniques for brain tumor classification and detection – A review by Usman Amjad, Asif Raza, Muhammad Fahad, Doaa Farid, Adnan Akhunzada, Muhammad Abubakar, Hira Beenish

“…Recent advancements in understanding the genetic abnormalities that underlie these tumors have shed light on their histo-pathological and biological characteristics, which support in better classification and prognosis. …”
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Amputations of Lower Limb in Subjects with Diabetes Mellitus: Reasons and 30-Day Mortality by Magdalena Walicka, Marta Raczyńska, Karolina Marcinkowska, Iga Lisicka, Arthur Czaicki, Waldemar Wierzba, Edward Franek

“…The most common disease diagnosed at discharge after LEA in diabetic patients was diabetes itself. Vascular pathologies, such as soft-tissue/bone/joint infections and ulcerations, were the next most common. …”
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Comparative efficacy and safety of first-line neoadjuvant therapy for early-stage non-small cell lung cancer based on immune checkpoint inhibitor therapy: a systematic review and n... by Linfeng Wang, Guangda Zheng, Yue Hu, Ayidana Maolan, Yue Luo, Yue Li, Rui Liu

“…For patients without programmed death-ligand 1(PD-L1) selection, Toripalimab plus chemotherapy provided the best Pathological complete response (PCR) benefit (OR = 32.89,95% CI:7.88-137.32), best Major Pathological response (MPR) benefit (OR = 10.25, 95% CI: 5.81–18.10) and best Event-free survival (EFS) benefit (HR = 0.40,95% CI: 0.28–0.57). …”
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Investigating the mechanisms of resveratrol in the treatment of gouty arthritis through the integration of network pharmacology and metabolics by Xiaomin Xu, Donghua Yu, Yu Wang, Xin Jiang, Fang Lu, Shumin Liu

“…The intervention of Res significantly reduced pathological damage, serum biochemical indicators, levels of inflammatory factors, and the activation of NF-κB, MAPK, and JAK/STAT signaling pathways in the model rats. …”
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PDZRN3 regulates adipogenesis of mesenchymal progenitors in muscle by Hiroki Iida, Minako Kawai-Takaishi, Yoshihiro Miyagawa, Yasuhiko Takegami, Akiyoshi Uezumi, Takeshi Honda, Shiro Imagama, Tohru Hosoyama

“…Introduction: Intramuscular adipose tissue (IMAT) is frequently formed in certain pathological conditions, such as biological aging, and ectopic fat accumulation leads to muscle weakness and a subsequent decline in physical function. …”
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Clinicopathological characteristics and outcomes of PLA2R related idiopathic membranous nephropathy in patients with seronegative PLA2R antibodies by Xue Li, Yang Shen, Yanchun Li, Lijie Ma, Qianmei Sun

“…Data on clinical features, pathological features, and outcomes were collected. Kaplan–Meier analysis of complete remission (CR) and partial remission (PR) comparing SAb−/GAg + and SAb+/GAg + patients. …”
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Prognostic stratification of patients with AJCC 2018 pN1 disease in stage III oral squamous cell carcinoma by Ming-Hsien Tsai, Hui-Ching Chuang, Yu-Tsai Lin, Tai-Lin Huang, Fu-Min Fang, Hui Lu, Chih-Yen Chien

“…Besides, there was no potential clinicopathological confounder which is significant associated with different pathological T classifications in this unique cohort. …”
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ROS-mediated M1 polarization-necroptosis crosstalk involved in Di-(2-ethylhexyl) phthalate-induced chicken liver injury by Guangxing Li, Menglin Wu, Kaiting Chen, Yue Xu, Xiandan Zhang, Yang Chen, Hong Zhang, Ruili Zhang, Xiaodan Huang

“…Macrophage polarization plays an important role in many physiological and pathological processes and regulates disease development. …”
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Effects of perioperative treatment of resectable adenocarcinoma of esophagogastric junction by immunotherapy (Adebrelimab) combined with chemotherapy (XELOX): protocol for a single... by Yingyi Li, Yuqin Cao, Xipeng Wang, Chengqiang Li, Liqin Zhao, Hecheng Li

“…The primary endpoint is the pathologic complete response (pCR) rate after perioperative neoadjuvant immunochemotherapy. …”
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Ferroptosis in Macrophage Impairment in Sepsis by Hongxuan Liu, Lei Li

“…Nonspecific immune dysfunction and immune imbalance are its important pathological features. Macrophages are important immune cells and one of the important components of innate and adaptive immunity. …”
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Optimal Treatment for Intermediate- and High-Risk, Nonmuscle-Invasive Bladder Cancer by A.P.M. van der Meijden

“…According to clinical and pathological factors the prognosis of a patient with non-muscle invasive bladder tumors can be assessed. …”
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Autopsy considerations from a science, technology and society perspectiva by Caridad Socorro Castro, Lian Roque Roque, Blanca Rosa Garcés Garcés, Magalys Oliver Cruz

“…Autopsy or necropsy is a method of anatomical-pathological study with a proven scientific and social value that arose in certain social conditions. …”
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Inflammatory Response and Immune Regulation in Brain-Heart Interaction after Stroke by Lihua Zou, Ruquan Han

“…Understanding the mechanism of the brain-heart interaction may be crucial for clinical treatment of pathological changes in CCS. Accumulating evidence suggests that the inflammatory response is involved in the brain-heart interaction after stroke. …”
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Gastrointestinal Tumors Mimicking Adnexal Masses: A Report of Three Cases and Review of the Literature by Berna Dilbaz, Burak Karadağ

“… It is important to determine the origin and malignancy risk of pelvic pathologies preoperatively and thus decide the route and extent of the surgery. …”
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Case Series of Intrauterine Subamniotic Hemorrhage by Momoko Owada, Yoshie Shibata, Shunji Suzuki

“…We present here 9 cases of intrauterine subamniotic hemorrhage to describe the pathological sequence. The definite diagnosis of subamniotic hemorrhage was mainly made macroscopically with the presence of hemorrhage or hematoma wrapped in the membrane on the fetal surface by postnatal examining of the placenta. …”
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