Case report: Personalized management of treatment resistance in advanced NSCLC patients with mutated epidermal growth factor receptor: special examples and literature review by Jun Wang, Jun Wang, Xiaojing Li, Shuang Dong, Sheng Hu, Fengming Ran, Yu Qian

“…The transformation of pathological types has brought great confusion to the clinical diagnosis and treatment process. …”
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Variabilities in Retinal Hemodynamics Across the Menstrual Cycle in Healthy Women Identified Using Optical Coherence Tomography Angiography by Vlad Constantin Donica, Alexandra Lori Donica, Irina Andreea Pavel, Ciprian Danielescu, Anisia Iuliana Alexa, Camelia Margareta Bogdănici

“…<b>Background:</b> Numerous conditions, both physiological and pathological, can influence changes in the retinal vascular architecture. …”
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The natural course of cystic pancreatic neuroendocrine tumours in MEN1 by Eline N M van Vliembergen, Carolina R C Pieterman, Annenienke C van de Ven, Arthur J A T Braat, Gerlof D Valk, Joanne M de Laat

“…In the second part, we investigated outcomes of pathological examinations, following resection of these lesions. …”
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A data driven approach for soft tissue biomarker identification linked to Chiari-like malformation and syringomyelia by Jake Cumber, Jake Cumber, Emma Scales-Theobald, Emma Scales-Theobald, Clare Rusbridge, Clare Rusbridge, Clare Rusbridge, Kevin Wells, Kevin Wells

“…This research aimed to identify cranial and spinal pathologies and neural morphologies linked to CM-P and SM in dogs using MRI scans and machine learning with the aim of identifying novel data driven biomarkers which could confirm CM-P and identify dogs at risk of developing SM. …”
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Partial unilateral ovarian torsion in a red-eared slider turtle (Trachemys scripta elegans) by Alessandro Vetere, Martina Gavezzoli, Lucia Victoria Bel, Rosanna Di Lecce, Martina Fumeo, Mattia Bonazzi, Francesco Di Ianni

“…Radiographs showed no pathological changes, while blood tests showed mild heterophilia. …”
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Role of PPARs in Progression of Anxiety: Literature Analysis and Signaling Pathways Reconstruction by Olga I. Rudko, Artemii V. Tretiakov, Elena A. Naumova, Eugene A. Klimov

“…Impairments in PPARG regulation and following MME and ACE peptidase expression impairments in amygdala may be the possible mechanism leading to pathological anxiety development, with brain CCK-4 accumulation being a key link. …”
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Epidemiological monitoring of avian influenza in the Republic of Crimea in 2019–2020 by D. V. Gadzevich, S. I. Danylchenko, N. V. Vorotilova, M. A. Pasunkina, V. A. Uppe, V. N. Irza, M. S. Volkov, N. G. Zinyakov

“…The natural biotope analysis conducted in 2019 and 2020 showed a decreased number of semiaquatic wild birds. The pathological material was sampled from semiaquatic and migratory wild birds, as well as from poultry kept in poultry farms and backyards. …”
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Cerebrospinal Fluid Biomarkers and Prediction of Conversion in Patients with Mild Cognitive Impairment: 4-Year Follow-Up in a Routine Clinical Setting by Alessia Lanari, Lucilla Parnetti

“…Among the stable MCI patients, none showed all three pathological values and only one subject had the pathological value of P-tau. …”
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Human PBMC-based humanized mice exhibit myositis features and serve as a drug evaluation model by Akiko Nishidate, Kana Takemoto, Yuki Imura, Mikako Murase, Ryu Yamanaka, Manami Kikuchi, Junpei Anan, Sayuka Kato, Airi Akatsuka, Sachiko Mochizuki, Yuzo Koda

“…In the present study, we demonstrate that immunodeficient mice transplanted with human peripheral blood mononuclear cells (hPBMCs) exhibit the key pathologic features of myositis observed in humans and develop graft-versus-host disease. …”
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NMR metabolic profiling of the liver following administrationof alcohol andthemushroom Ganoderma lucidum in rats by M. S. Krestina, O. B. Shevelev, I. V. Koptyug, L. A. Gerlinskaya, S. E. Peltek, A. E. Akulov

“…Noteworthy, alcohol consumption did not cause pathological changes, but stimulated hepatocyte proliferation. …”
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Acanthopanax versus 3-Methyladenine Ameliorates Sodium Taurocholate-Induced Severe Acute Pancreatitis by Inhibiting the Autophagic Pathway in Rats by Xiaohong Wang, Guoxiong Zhou, Chun Liu, Ronglong Wei, Shunxing Zhu, Yuefen Xu, Mengjie Wu, Qing Miao

“…Serum amylase levels, protein, and mRNA expression levels of nucleus NF-κB p65, LC3-II, and Beclin-1 protein, mRNA expression levels of PI3K-III, and pathological score of the pancreas in both treatment groups were significantly lower than those in SAP group at 12 and 24 h after operation (P<0.05 or 0.01). …”
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Treatment of a medial plica in the knee among German knee surgeons – The Plica Survey by Svea Faber, Philipp W. Winkler, Ralf Henkelmann, Theresa Diermeier, Wolf Petersen, Maurice Balke, Sebastian Metzlaff, Sebastian Colcuc, Gerald Zimmermann, Philip P. Roessler, Thomas R. Niethammer

“…While often an anatomical relic without pathological significance, inflammation or mechanical irritation of this structure can lead to plica syndrome, causing significant clinical symptoms. …”
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Intrascrotal Dedifferentiated Leiomyosarcoma Originating from Dartos Muscle by Taro Teshima, Sayuri Takahashi, Shoichi Nagamoto, Hideyo Miyazaki, Tohru Nakagawa, Tetsuya Fujimura, Hiroshi Fukuhara, Haruki Kume, Yukio Homma

“…The tumor and the right testis were excised with the adhered right scrotal skin. The pathological diagnosis was pleomorphic leiomyosarcoma with dedifferentiation originating from the dartos muscle. …”
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Persistent Increase in Serum Alkaline Phosphatase in a Patient with Monoclonal Gammopathy of Undefined Significance by I. Ramasamy

“…The identification of macro-ALP is important to rule out pathological causes of increased ALP activity and to avoid unnecessary diagnostic investigation. …”
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Unusual Cause of Persistent Epistaxis with Severe Anemia in a Child by Yilkal Zemene, Tadele Hailu, Josh Wiedermann

“…Epistaxis in children can be caused by different systemic and local pathologies. Respiratory infections, nasal mucosa dryness, and foreign bodies are some local causes of bleeding from the nose. …”
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An Examination of the Role of Transcriptional and Posttranscriptional Regulation in Rhabdomyosarcoma by Alexander J. Hron, Atsushi Asakura

“…Additionally, the subtypes of RMS are reviewed along with the involvement of basic helix-loop-helix (bHLH) proteins, Pax proteins, and microRNAs in normal and pathologic myogenesis. Finally, the current and potential future treatment options for RMS are outlined.…”
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Influence of Electric Current and Magnetic Flow on Firing Patterns of Pre-Bötzinger Complex Model by Wenchao Ji, Moutian Liu, Lixia Duan

“…The dynamics of neuronal firing activity is vital for understanding the pathological respiratory rhythm. Studies on electrophysiology show that the magnetic flow is an essential factor that modulates the firing activities of neurons. …”
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Abnormalities in Glutamate Metabolism and Excitotoxicity in the Retinal Diseases by Makoto Ishikawa

“…In this review, we describe the present knowledge concerning the retinal glutamate metabolism under the physiological and pathological conditions.…”
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Syntomatic Tarlov Cyst. Case presentation by Jorge Luis Castillo López, María E. Jerves Crespo, Victoria E. Solís Espín, Juan C. Vargas Parra

“…Tarlov or perineural cysts are pathologic deformations located in the space between the Perineurium and endoneurium of spinal roots close to the posterior root ganglion. …”
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Survival from Primary Abdominal Lymphoma Presenting with a Mass and Obstructive Jaundice by Hugh J Freeman, Andrew M Seal

“…Subsequent laboratory investigations confirmed the presence of cholestasis associated with an obstructing mass in the region of the common hepatic duct. Pathological evaluation of the mass revealed a localized abdominal lymphoma. …”
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