Cardiovascular sudden death and its progression between cross-disciplinarity and cross-sectorial approach by Luis A. Ochoa Montes, Rafael E. Araujo González, Daisy Ferrer Marrero

“…The complexity of its physio-pathologic elements, and the diversity of the population groups in which it takes place demand a cross-discipline study. …”
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Ascending to descending aortic prosthesis with reimplantation of brachiocephalic vessels in aneurysm of the arch and descending aorta for hypoplasia of the arch and coarctation of... by B.M. Todurov, O.V. Zelenchuk, S.M. Sudakevych, A.Yu. Shkandala, N.S. Gnoyanko

“…Thoracic aortic aneurysm is one of the most serious pathologies of cardiovascular surgery. Occurrence of an aneurysm in the proximal or distal part of the aortic arch is a recognized complication of uncorrected aortic coarctation and is associated with a significant risk of aortic rupture. …”
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Intestinal Necrosis due to Giant Ovarian Cyst: A Case Report by Ali Duran, Fulay Yilmaz Duran, Fevzi Cengiz, Ozgur Duran

“…Intestinal pathologies due to ovarian cyst are observed rarely. …”
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New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature by Elvis Henrique Santos Andrade, Pedro Mario Pan, Paula F. Ramalho da Silva, Ary Gadelha

“…Prolactinomas are the commonest pituitary adenomas and the major pathological cause of hyperprolactinaemia. Symptomatic prolactinomas are treated mainly by dopamine agonists; surgery and radiotherapy are options for nonresponders. …”
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Fused Double Supernumerary Premolars of the Mandible: A Rare Case by Ali Azhar Dawasaz, Syed Sadatullah, Syed Kamran Bokhari

“…Supernumerary premolars are likely to undergo pathological changes. The most commonly encountered complications with these teeth are dentigerous cyst and root resorption of the adjacent tooth. …”
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Ischemic Postconditioning Mitigates Retinopathy in Tree Shrews with Diabetic Cerebral Ischemia by Ling Zhao, Qiwei Liao, Yueting Zhang, Shufen Tan, Shuqing Li, Tingyu Ke

“…Tree shrews with diabetes had thinned retina with disordered structures, and these pathological changes were aggravated after cerebral ischemia. …”
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Chronic Isolated Fallopian Tube Torsion in a Sexually Inactive Adolescent Female Diagnosed Peroperatively by Yuhya Hirahara, Koichi Nagai, Kazunori Mukaida

“…Following laparoscopy, the patient’s watery discharge was resolved. Pathological findings confirmed no signs of malignancy. …”
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Secondary Circulating Prostate Cells Predict Biochemical Failure in Prostate Cancer Patients after Radical Prostatectomy and without Evidence of Disease by Nigel P. Murray, Eduardo Reyes, Nelson Orellana, Cynthia Fuentealba, Leonardo Bádinez, Ruben Olivares, José Porcell, Ricardo Dueñas

“…Serial blood samples were taken during followup after RP, mononuclear cells were obtained by differential gel centrifugation, and CPCs identified using standard immunocytochemistry using anti-PSA monoclonal antibodies. Age, pathological stage (organ confined, nonorgan confined), pathological grade, margin status (positive, negative), extracapsular extension, perineural, vascular, and lymphatic infiltration (positive, negative) were compared with the presence/absence of CPCs and with and without biochemical failure. …”
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Immune Checkpoint Blockade in Melanoma – Earlier is Better? by Vincas Urbonas, Audrius Dulskas, Edita Baltruškevičienė, Daiva Dabkevičienė

“…This approach boasts a considerable success in high pathologic response rate, a factor directly linked to survival rates. …”
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Oxidative stress and dysregulated long noncoding RNAs in the pathogenesis of Parkinson’s disease by Jialu Wang, Meitong Liu, Jiuhan Zhao, Pan Hu, Lianbo Gao, Shen Tian, Jin Zhang, Huayan Liu, Xiaoxue Xu, Zhenwei He

“…Therefore, modulating the levels of specific lncRNAs may alleviate pathological oxidative damage and have neuroprotective effects. …”
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Protective effects of myrtenol against paraquat-induced toxicity in rats by Fatemeh Amin, Hosein Basirat, Najmeh Parvaz, Morteza Khademalhosseini, Elham Hakimizadeh, Iman Fatemi

“…Various hematological, oxidative, inflammatory, and pathological indices were measured at the conclusion of the treatment period. …”
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Impact of the Siewert Classification on the Outcome of Patients Treated by Preoperative Chemoradiotherapy for a Nonmetastatic Adenocarcinoma of the Oesophagogastric Junction by Laurence Moureau-Zabotto, Eric Teissier, Didier Cowen, David Azria, Steve Ellis, Michel Resbeut

“…The aim of the study is to analyze the impact of the Siewert classification on the pathological complete response (pcR), pattern of failure, and general outcome of patients treated, by preoperative chemoradiotherapy and surgery for an gastroesophageal junction adenocarcinoma (OGJA). …”
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Effects of central administration of the human Tau proteinon the <i>Bdnf, Trkb, p75, Mapt, Bax</i> and <i>Bcl-2</i> genes expression in the mouse brain by A. S. Oreshko, A. Ya. Rodnyy, D. V. Bazovkina, V. S. Naumenko

“…Recently, more studies have been directed to the investigation of the processes leading to the formation of neurofibrillary tangles consisting of hyperphosphorylated microtubule-associated Tau proteins. Pathological aggregation of this protein leads to the development of neurodegeneration associated with impaired neurogenesis and apoptosis. …”
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Nomogram for Predicting Survival in Advanced Gastric Cancer after Neoadjuvant Chemotherapy and Radical Surgery by Yonghe Chen, Dan Liu, Jian Xiao, Jun Xiang, Aihong Liu, Shi Chen, Junjie Liu, Xiansheng Hu, Junsheng Peng

“…Younger age (<60 years old), increased examined lymph nodes (exLNs), successful R0 resection, the achievement of pathological complete response (pCR), and acceptance of adjuvant chemotherapy were positive predictors of survival. …”
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STAPHYLOCOCCAL INFECTION IN DOGS (DIAGNOSIS, TREATMENT AND PREVENTION) by V. B. Rudenko, P. A. Rudenko, S. G. Semushina, I. A. Pakhomova

“…In addition to the pathological agent, the following extra factors are needed for the disease clinical manifestation: immune deficiency, metabolic disorder, parasitic disease, manipulations resulting in damage to the skin and mucosa integrity. …”
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Combined metabolomics and 16S rDNA sequence analyses of the gut microbiome reveal the action mechanism of Fructus Akebiae against hepatic fibrosis by Rong-Rong Wu, Duo-Rui Nie, Fang-Hui He, Zhi-Hang Li, Fei Xu, Fei Xu, Fei Xu

“…ObjectivesTo explore the mechanism underlying the effect of Fructus Akebiae (FAE) against hepatic fibrosis in mice through combined network pharmacology, liver metabolomics, and 16S rDNA analyses of the gut microbiota.MethodsIn this study, we randomly divided mice into the control, model, FAE high-dose, FAE medium-dose, and FAE low-dose groups to analyze the pathological changes in the hepatic fibrosis and levels of the α-SMA, collagen 1, Nuclear Factor Kappa B (NF-κ B), Toll Like Receptor 4 (TLR4). …”
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Exploring Current Evidence on the Past, the Present, and the Future of the Heart Team: A Narrative Review by Alexandru Burlacu, Adrian Covic, Mircea Cinteza, Paula Madalina Lupu, Radu Deac, Grigore Tinica

“…Envisioned as a tool for optimizing the management of various complex cardiovascular pathologies, Heart Team should simplify and facilitate the activity in the cardiovascular ward. …”
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A “Catastrophic” Heparin-Induced Thrombocytopenia by D. Barcellona, M. Melis, G. Floris, A. Mameli, A. Muroni, G. Defazio, F. Marongiu

“…In contrast to other pathological conditions which lead to thrombocytopenia and bleeding complications, HIT results in a paradoxical prothrombotic state. …”
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The Emerging Roles of the Calcineurin-Nuclear Factor of Activated T-Lymphocytes Pathway in Nervous System Functions and Diseases by Maulilio John Kipanyula, Wahabu Hamisi Kimaro, Paul F. Seke Etet

“…Its role in physiological and pathological processes is still controversial. However, available data suggest that its beneficial and detrimental effects are context-dependent. …”
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Seizure-Induced Regulations of Amyloid-β, STEP61, and STEP61 Substrates Involved in Hippocampal Synaptic Plasticity by Sung-Soo Jang, Sara E. Royston, Gunhee Lee, Shuwei Wang, Hee Jung Chung

“…Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline. Pathologic accumulation of soluble amyloid-β (Aβ) oligomers impairs synaptic plasticity and causes epileptic seizures, both of which contribute to cognitive dysfunction in AD. …”
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