Potato spindle tuber viroid by A. V. Kochetov, A. Y. Pronozin, N. V. Shatskaya, D. A. Afonnikov, O. S. Afanasenko

“…There are PSTVd strains with a severe, a moderate or a mild pathological effect. Interestingly, viroid replication itself does not necessarily induce strong morphological or physiological symptoms. …”
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Distinct subcellular localization of tau and alpha-synuclein in lewy body disease by D. Luke Fischer, Marissa Menard, Omar Z. Abdelaziz, Nicholas M. Kanaan, Virginia G. Cobbs, Richard E. Kennedy, Geidy E. Serrano, Thomas G. Beach, Laura A. Volpicelli-Daley

“…However, p-α-syn rarely colocalized with p-tau or PAD-tau, although the overlap of p-α-syn with PAD-tau was significantly associated with LBD. In the rare cases pathologic α-syn and pathologic tau were found in the same Lewy body or Lewy neurite, tau appeared to surround α-syn but did not colocalize within the same structure. …”
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Simultaneous Acute Cholecystitis and Acute Appendicitis Treated by a Single Laparoscopic Operation by Jonas P. DeMuro

“…The laparoscopic approach is ideal for dealing with multiple, simultaenous abdominal pathologies.…”
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Congenital Pulmonary Malformation in Children by Montasser Nadeem, Basil Elnazir, Peter Greally

“…They represent a spectrum of abnormal development rather than discrete pathological entities. They are caused by aberrant embryological lung development which occurs at different stages of intrauterine life.…”
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Genetic Analysis of Undiagnosed Juvenile GM1-Gangliosidosis by Microarray and Exome Sequencing by Ahmed Bouhouche, Houyam Tibar, Yamna Kriouale, Mohammed Jiddane, Imane Smaili, Naima Bouslam, Ali Benomar, Mohamed Yahyaoui, Elmostafa El Fahime

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Les patrimoines mobiliers scientifique et technique : spécificités de leur restauration, de leur conservation et de leur valorisation by Philippe Tomsin

“…The scientific and technical movable heritage, because of its materials and special pathologies, gives some specific problems of conservation and restoration. …”
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Cholecystocolonic Fistulas from Diverticulosis: A Potentially Missable Cause of Liver Abscesses by Ben Warner, Terry Wong, Philip Berry

“…In this case report, we found both pathologies and emphasise the need to study cholangiograms carefully so as not to miss alternative diagnoses.…”
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SHOULDER PAIN, ULTRASOUND CHANGES, AND FUNCTIONAL PERFORMANCE IN OBESE PATIENTS by Fabiana Alves Costa Menegassi, Glaucus Cajaty Martins, Zartur José Barcelos Menegassi, Sérgio Augusto Lopes de Souza, Bianca Gutfilen, Fábio Ramos Costa

“…Conclusions: These findings suggest that being overweight is an important exacerbating factor for shoulder pain, lower shoulder functional performance and pathological changes of the rotator cuff and c-reactive protein test. …”
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Prostaglandin Receptor Signaling in Disease by Toshiyuki Matsuoka, Shuh Narumiya

“…These studies have revealed the roles of PG receptor signaling in various pathological conditions, and suggest that selective manipulation of the prostanoid receptors may be beneficial in treatment of the pathological conditions. …”
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Intravitreal Devices for the Treatment of Vitreous Inflammation by John B. Christoforidis, Susie Chang, Angela Jiang, Jillian Wang, Colleen M. Cebulla

“…The eye is a well-suited organ for local delivery of therapeutics to treat vitreous inflammation as well as other pathologic conditions that induce visual loss. Several conditions are particularly challenging to treat and often require chronic courses of therapy. …”
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Suxamethonium-Induced Hyperkalemia: A Short Review of Causes and Recommendations for Clinical Applications by Henrik Lynge Hovgaard, Peter Juhl-Olsen

“…These pathologic conditions include upper and lower neuron injuries, major burns, trauma, immobility, muscle tumors, muscular dystrophy, and prolonged critical illness. …”
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The Role of Insulin Receptor Isoforms in Diabetes and Its Metabolic and Vascular Complications by O. Escribano, N. Beneit, C. Rubio-Longás, A. R. López-Pastor, A. Gómez-Hernández

“…The differential physiological and pathological role of both isoforms is not completely known, and it is determinant the different binding affinity for insulin-like growth factor. …”
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Exosome-Like Vesicles as New Mediators and Therapeutic Targets for Treating Insulin Resistance and β-Cell Mass Failure in Type 2 Diabetes Mellitus by Qian Ge, Xin Xin Xie, Xiaoqiu Xiao, Xi Li

“…Pathologic conditions associated with type 2 diabetes (such as high blood glucose, inflammation, hypoxia, and fatty acids) can alter the quantity and components of ELVs secreted from the pancreas or peripheral insulin-targeting tissues. …”
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Surprise Lymph Node Histology in a Patient with Ovarian Serous Carcinoma by Jayanthi Karunanithi, Inny Busmanis

“…This case is also unusual, as although PEComas have been described as arising in the female genital tract, the associated phenomenon of endometriosis is exceedingly rare, and this is the first known reported case of lymph nodes harbouring a similar combination of pathologies.…”
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Role of Matrix Metalloproteinases in Angiogenesis and Its Implications in Asthma by Khuloud Bajbouj, Rakhee K. Ramakrishnan, Qutayba Hamid

“…Angiogenesis and associated vascular remodeling are one of the pathological hallmarks of asthma. The mechanisms underlying angiogenesis in asthmatic airways and its clinical relevance represent a relatively nascent field in asthma when compared to other airway remodeling features. …”
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High Sensitivity Method to Estimate Distribution of Hyaluronan Molecular Sizes in Small Biological Samples Using Gas-Phase Electrophoretic Mobility Molecular Analysis by Lan Do, Christen P. Dahl, Susanne Kerje, Peter Hansell, Stellan Mörner, Ulla Lindqvist, Anna Engström-Laurent, Göran Larsson, Urban Hellman

“…Hyaluronan is a negatively charged polydisperse polysaccharide where both its size and tissue concentration play an important role in many physiological and pathological processes. The various functions of hyaluronan depend on its molecular size. …”
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Morphine for the Treatment of Pain in Sickle Cell Disease by Mihir Gupta, Lilian Msambichaka, Samir K. Ballas, Kalpna Gupta

“…Due to opioid-induced endothelial-, mast cell-, renal mesangial-, and epithelial-cell-specific effects and proinflammatory as well as growth influencing signaling, it is likely that when used for analgesia, opioids may have organ specific pathological effects. Experimental and clinical studies, even though extremely few, suggest that opioids may exacerbate existent organ damage and also stimulate pathologies of their own. …”
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Case report: From misdiagnosis to timely detection: a clinical and imaging guide to neurological presentations of diffuse large B-cell lymphoma—insights from six cases by Chunxiao Yang, Zihua Gong, Tao Wang, Huijuan Yuan, Weinan Na, Wei Xie, Shengyuan Yu

“…These presentations precipitated multiple erroneous diagnoses pertaining to nervous system pathologies, culminating in a median diagnostic latency of 8 months.ConclusionThe differential diagnostic process for the misdiagnosed conditions in these cases has been meticulously revisited, enhancing the diagnostic acumen of neurologists. …”
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Сurrent state of clinical significance of early kidney injury markers by D. N. Khotko, A. I. Khotko, A. I. Tarasenko, A. O. Efimova

“…Today it is most relevant to conduct the search for biomarkers of acute and chronic renal lesions at patients with urolithiasis to detect pathological changes in the kidneys and to determine their nature at an early stage of diagnosis.Improved diagnostic techniques destined to provide a detailed picture of the development of the pathological process in patients with urolithiasis will make it possible to prevent renal failure development at an early stage in this category of patients.…”
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Scrotal Apocrine Adenocarcinoma with Pagetoid Phenomenon and Inguinal Lymph Node Metastases by Aristeidis Hristos Zibis, Apostolos Haralampos Fyllos, Sophia Havaki, Sotirios Sotiriou, Georgios Kotakidis, Dimitrios Leonidas Arvanitis

“…We report a case of scrotal apocrine adenocarcinoma in a 72-year-old Caucasian male which was initially presented as a reddish superficial lesion which in time became an ulcerated nodule. The initial pathological examination showed an apocrine adenocarcinoma with pagetoid phenomenon. …”
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