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    Programmed Cell Death Ligand 1 (PD-L1) and major Histocompatibility Complex Class I (MHC Class I) Expression Patterns and Their Pathologic Associations in triple-Negative Breast Cancer by Kaewkedsri P, Intarawichian P, Jessadapattarakul S, Kunprom W, Koonmee S, Thanee M, Somintara O, Wongbuddha A, Chadbunchachai P, Nawapun S, Aphivatanasiri C

    Published 2025-02-01
    “…Ponkrit Kaewkedsri,1 Piyapharom Intarawichian,1 Sirawich Jessadapattarakul,1 Waritta Kunprom,1 Supinda Koonmee,1 Malinee Thanee,1 Ongart Somintara,2 Anongporn Wongbuddha,2 Payia Chadbunchachai,3 Supajit Nawapun,3 Chaiwat Aphivatanasiri1 1Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 2Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 3Department of Radiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandCorrespondence: Chaiwat Aphivatanasiri, Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, Email chaiap@kku.ac.thPurpose: This study aims to investigate the clinicopathological characteristics of triple-negative breast cancer (TNBC) in relation to programmed cell death ligand 1 (PD-L1) and major histocompatibility complex class I (MHC class I) expression, with a focus on their prognostic significance.Patients and Methods: A retrospective analysis was conducted on formalin-fixed paraffin-embedded (FFPE) tissue samples from 148 TNBC patients diagnosed between 2008 and 2021. …”
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