O-GlcNAcylation attenuates ischemia-reperfusion-induced pulmonary epithelial cell ferroptosis via the Nrf2/G6PDH pathway by Liuqing Yang, Hexiao Tang, Jin Wang, Dawei Xu, Rui Xuan, Songping Xie, Pengfei Xu, Xinyi Li

“…Abstract Background Lung ischemia–reperfusion (I/R) injury is a common clinical pathology associated with high mortality. The pathophysiology of lung I/R injury involves ferroptosis and elevated protein O-GlcNAcylation levels, while the effect of O-GlcNAcylation on lung I/R injury remains unclear. …”
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CEST imaging combined with 1H-MRS reveal the neuroprotective effects of riluzole by improving neurotransmitter imbalances in Alzheimer’s disease mice by Yuanyu Shen, Xiaolei Zhang, Siqi Liu, Lijing Xin, Wentao Xuan, Caiyu Zhuang, Yue Chen, Beibei Chen, Xinhui Zheng, Renhua Wu, Yan Lin

“…At the study endpoint, immunohistochemistry, Nissl staining, and Western blot were used to evaluate the brain pathology, neuronal survival, and protein expression. …”
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Immune Dysfunction in Rett Syndrome Patients Revealed by High Levels of Serum Anti-N(Glc) IgM Antibody Fraction by Anna Maria Papini, Francesca Nuti, Feliciana Real-Fernandez, Giada Rossi, Caterina Tiberi, Giuseppina Sabatino, Shashank Pandey, Silvia Leoncini, Cinzia Signorini, Alessandra Pecorelli, Roberto Guerranti, Solange Lavielle, Lucia Ciccoli, Paolo Rovero, Claudio De Felice, Joussef Hayek

“…These findings offer a new insight into the mechanism underlying the Rett disease as they unveil the possible involvement of the immune system in this pathology.…”
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Investigating the dual causative pathways linking immune cells and venous thromboembolism via Mendelian randomization analysis by Ning Qi, Zhuochen Lyu, Lu Huang, Yun Zhao, Wan Zhang, Xinfeng Zhou, Yang Zhang, Jiasen Cui

“…While this study is exploratory and needs validation, the findings of this study are hypothesis-generating with resect to the mechanisms underlying VTE and encourage further investigation into the role of immune activity in VTE pathology. Graphical abstract…”
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Hubungan Kadar Laktat Dehidrogenase dengan Stadium Limfoma Maligna Non Hodgkin di Rumah Sakit Dr. M. Djamil Padang periode Desember 2009 sampai Maret 2013 by Dian Rahma Kasir, Irza Wahid, Hafni Bachtiar

“…Based on research conducted by Olivia Putri Perdana in anatomic pathology at the Faculty of Medicine, University of Andalas that the data obtained during the January 1997 - December 2001 there were 70 (81.39%) patients with non -Hodgkin's malignant lymphoma of the overall malignant lymphoma patients.…”
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EHMT2‐mediated R‐loop formation promotes the malignant progression of prostate cancer via activating Aurora B by Yuyang Zhang, Mingqin Su, Yiming Chen, Li Cui, Wei Xia, Renfang Xu, Dong Xue, Xiansheng Zhang, Xingliang Feng

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Hubungan Daerah Tempat Tinggal dengan Gambaran Histopatologi Karsinoma Tiroid pada Masyarakat Sumatera Barat by Eka Putri, Daan Khambri, Selfi Renita Rusdji

“…This analytic research with observational design obtaining secondary data from Pathology Anatomy Laboratory of Medical Faculty of Andalas University and medical record of M. …”
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Increased Frequency of Circulating Follicular Helper T Cells in Children with Hand, Foot, and Mouth Disease Caused by Enterovirus 71 Infection by Jianping Wu, David Cui, Xianzhi Yang, Jianzhou Lou, Jie Lin, Xianfei Ye, Zhimei Qin, Li Huang, Dejian Zhao, Zhaoxia Huo, Guoliang Xie, Shufa Zheng, Fei Yu, Liwei Lu, Yu Chen

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Genetic and peripheral biomarkers of comorbid posttraumatic stress disorder and traumatic brain injury: a systematic review by Kiriana Cowansage, Reshmi Nair, Jose M. Lara-Ruiz, Daniel E. Berman, Courtney C. Boyd, Tiffany L. Milligan, Daniel Kotzab, Dawn M. Bellanti, Lisa M. Shank, Maria A. Morgan, Derek J. Smolenski, Ida Babakhanyan, Nancy A. Skopp, Daniel P. Evatt, Marija S. Kelber

“…An elevated circulating level of the pro-inflammatory cytokine IL-6 was the most consistently replicated blood-based indicator of comorbid illness, compared to mTBI alone.ConclusionSeveral genetic and protein markers of cellular injury and inflammation appear to be promising indicators of chronic pathology in comorbid TBI and PTSD. Additional research is needed to determine how such factors indicate, predict, and contribute to comorbidity and to what extent they represent viable targets for the development of novel diagnostic tools and therapeutic interventions.…”
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Deciphering the role of IL17RA in psoriasis and chronic mucocutaneous candidiasis: shared pathways and distinct manifestations by Ayat Kadhi, Ayat Kadhi, Ayat Kadhi, Edward Eid, Michel J. Massaad, Inaam El-Rassy, Dana Maria Khoury, Yutaka Shimomura, Nelly Rubeiz, Mazen Kurban, Mazen Kurban, Mazen Kurban, Georges Nemer, Georges Nemer

“…Utilizing whole exome and transcriptomic sequencing, we meticulously investigated the genetic underpinnings and molecular pathways underlying these complex pathologies. RNA sequencing was performed on a skin biopsy to confirm transcriptomic profiles associated with these conditions.ResultsWe identified a novel bi-allelic variant (NM_014339.6, c.1173C>G A) within the interleukin 17 receptor type A (IL17RA) gene, resulting in a premature stop codon (p. …”
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Liver Metastases in Pancreatic Acinar Cell Carcinoma Treated with Selective Internal Radiation Therapy with Y-90 Resin Microspheres by Felipe Nasser, Joaquim Maurício Motta Leal Filho, Breno Boueri Affonso, Francisco Leonardo Galastri, Rafael Noronha Cavalcante, Diego Lima Nava Martins, Vanderlei Segatelli, Lilian Yuri Itaya Yamaga, Rene Claudio Gansl, Bernardino Tranchesi Junior, Antônio Luiz de Vasconcellos Macedo

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Perbedaan Kadar Superokside Dismutase pada Remaja dengan Dismenore Primer dan Tanpa Dismenore Primer by Yanti ., Ermawati ., Eliza Anas

“…</p><p><strong>Kata kunci:</strong> remaja, dismenore, antioksidan, superokside dismutase</p><p> </p><p><strong><em>Abstract</em></strong></p><p class="normal"><em>Primary dysmenorrhoe is  a painful menstrual cramps without obvious pathology. Cramps is lasting for one day or more, accaompanied by nausea, diarrhea and headache. …”
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Gastric Cancer Maximum Tumour Diameter Reduction Rate at CT Examination as a Radiological Index for Predicting Histopathological Regression after Neoadjuvant Treatment: A Multicent... by Maria Antonietta Mazzei, Giulio Bagnacci, Francesco Gentili, Andrea Nigri, Veronica Pelini, Carla Vindigni, Francesco Giuseppe Mazzei, Gian Luca Baiocchi, Frida Pittiani, Paolo Morgagni, Enrico Petrella, Gianni Mura, Beatrice Verdelli, Maria Bencivenga, Simone Giacopuzzi, Daniele Marrelli, Franco Roviello, Luca Volterrani

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Dynamics of retinal changes in early-stage Parkinson’s disease by Ane Murueta-Goyena, Sara Teijeira-Portas, Elisa Blanco Martín, Raquel Vázquez-Picón, Blanca Ruiz Bajo, Jone Bocos, Jorge Sánchez-Molina, Patricia Alves Dias, Ioana Croitoru, Iñaki Rodríguez Agirretxe, Rocío Del Pino, Marian Acera, Beatriz Tijero, Oihane Sáez-Atxukarro, David Romero-Bascones, Juan Carlos Gómez-Esteban, Javier Aritz Urcola, Javier Ruiz Martínez, Iñigo Gabilondo

“…Abstract Parkinson’s disease (PD) is a neurodegenerative disorder primarily characterized by motor symptoms, with emerging evidence suggesting retinal pathology, particularly in the ganglion cell-inner plexiform layer (GCIPL), detectable via optical coherence tomography (OCT). …”
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Effects of isoquinoline alkaloids as an alternative to antibiotic on oxidative stress, inflammatory status, and cecal microbiome of broilers under high stocking density by Kittisak Insawake, Thaweesak Songserm, Ornprapun Songserm, Atthawoot Plaiboon, Nitipong Homwong, Kazeem D. Adeyemi, Konkawat Rassmidatta, Yuwares Ruangpanit

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USP35 promotes the growth of ER positive breast cancer by inhibiting ferroptosis via BRD4-SLC7A11 axis by Jiawei Cao, Tao Wu, Tong Zhou, Zewei Jiang, Yinrui Ren, Jiawei Yu, Jiayi Wang, Changrui Qian, Guang Wu, Licai He, Hongzhi Li, Rixu Lin, Min Liu, Haihua Gu

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The protein structurome of Orthornavirae and its dark matter by Pascal Mutz, Antonio Pedro Camargo, Harutyun Sahakyan, Uri Neri, Anamarija Butkovic, Yuri I. Wolf, Mart Krupovic, Valerian V. Dolja, Eugene V. Koonin

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Inducing salt stress tolerance in bitter gourd (Momordica chanrantia) through seed treatment with chitosan by Ahsan Ali, Fiaz Hussain Ferdosi, Mubeen Sarwar, Sumreen Anjum, Zain Mushtaq, Mehwish Liaquat, Muhammad Taqqi Abbas, Moazzam Anees, Muhammad Rizwan Tariq, M. Irfan Ashraf, Abdulrahman Alasmari, Md Sabir Ahmed Mondol, Gholamreza Abdi

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Ferroptosis Transcriptional Regulation and Prognostic Impact in Medulloblastoma Subtypes Revealed by RNA-Seq by Christophe Desterke, Yuanji Fu, Jenny Bonifacio-Mundaca, Claudia Monge, Pascal Pineau, Jorge Mata-Garrido, Raquel Francés

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A case-control genome-wide association study of estimated breeding values for resistance to gastrointestinal nematodes in two local dairy sheep breeds by C. Persichilli, S. Biffani, G. Senczuk, M. Di Civita, M.K. Bitew, A. Bosco, L. Rinaldi, S. Grande, G. Cringoli, F. Pilla

“…Among these, genes involved in the physiology or pathology of the gastrointestinal tract, in adaptive processes and in production traits, were detected. …”
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