Therapeutic efficacy and mechanism of artesunate for mouse model of polycystic ovary syndrome by WANG Xueling, WANG Xueling, ZHONG Peiling, ZHONG Peiling, ZHAO Zhipeng

“…The estrous cycle was observed, and HE staining was performed for pathological changes in the ovary and uterus. Immunofluorescence assay was employed to measure the expression of p-eIF2α, ATF4 and CHOP in the ovarian tissue. …”
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A systematic review of Streptococcus Mutans and Veillonellae species interactions in dental caries progression: Positive or Negative impact? [version 2; peer review: 1 approved, 2... by Faizul Hasan, Prawati Nuraini, Ariadna Adisattya Djais, Ervina Restiwulan Winoto, Tantiana Tantiana, Rini Devijanti Ridwan, Juni Handajani, Rajesh Ramasamy, Silvia Anitasari, Hendrik Setia Budi

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Strengthening identification and characterization of causes of perinatal deaths in Kaski district of Nepal (Perinatal MITS Nepal) by Nuwadatta Subedi, Sunita Ranabhat, Sanjib Mani Regmi, Mukesh Mallik, Dela Singh, Shree Krishna Shrestha, Bandana Gurung, Arjun Bhattarai, Madan Prasad Baral, Sudhir Raman Parajuli, Ramchandra Bastola, Junu Shrestha, Sahisnuta Basnet, Eva Gauchan, Sabita Paudel

“…The outcome will be helpful to standardize methods to establish the accurate causes of perinatal deaths and develop strategies to minimize the deaths. The selected pathological investigations can be integrated into the existing death surveillance system in order to effectively determine the causes of death.…”
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The APOE∗3-Leiden Heterozygous Glucokinase Knockout Mouse as Novel Translational Disease Model for Type 2 Diabetes, Dyslipidemia, and Diabetic Atherosclerosis by Marianne G. Pouwer, Suvi E. Heinonen, Margareta Behrendt, Anne-Christine Andréasson, Arianne van Koppen, Aswin L. Menke, Elsbet J. Pieterman, Anita M. van den Hoek, J. Wouter Jukema, Brendan Leighton, Ann-Cathrine Jönsson-Rylander, Hans M. G. Princen

“…E3L and E3L.GK+/− mice developed NASH with severe inflammation and fibrosis which, however, was not altered by introduction of the defective GK phenotype, whereas mild kidney pathology with tubular vacuolization was present in all three phenotypes. …”
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An animal model of severe acute respiratory distress syndrome for translational research by Kuo-An Chu, Chia-Yu Lai, Yu-Hui Chen, Fu-Hsien Kuo, I.-Yuan Chen, You-Cheng Jiang, Ya-Ling Liu, Tsui-Ling Ko, Yu-Show Fu

“…Abstract Background Despite the fact that an increasing number of studies have focused on developing therapies for acute lung injury, managing acute respiratory distress syndrome (ARDS) remains a challenge in intensive care medicine. Whether the pathology of animal models with acute lung injury in prior studies differed from clinical symptoms of ARDS, resulting in questionable management for human ARDS. …”
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Development, validation, and clinical application of a machine learning model for risk stratification and management of cervical cancer screening based on full-genotyping hrHPV tes... by Binhua Dong, Zhen Lu, Tianjie Yang, Junfeng Wang, Yan Zhang, Xunyuan Tuo, Juntao Wang, Shaomei Lin, Hongning Cai, Huan Cheng, Xiaoli Cao, Xinxin Huang, Zheng Zheng, Chong Miao, Yue Wang, Huifeng Xue, Shuxia Xu, Xianhua Liu, Huachun Zou, Pengming Sun

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Impact of Ecobiol plus ® feed additive on growth performance, physiological response, oxidative status and immunological status of Nile tilapia (Oreochromis niloticus) fingerlings... by Amira A. Omar, Doaa H. Assar, Mustafa Shukry, Aya Abo El-Ezz, Foad A. Farrag, Wesam E. Abd El-Aziz, Eman M. Moustafa

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Symptomatic Pituitary Metastasis as Initial Manifestation of Renal Cell Carcinoma: Case Report and Review of Literature by Gunjan Y. Gandhi, Russell Fung, Patrick E. Natter, Raafat Makary, K. C. Balaji

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Vaccines in the fight against antimicrobial resistance – perspectives from South Africa by A Brink, A Kgasi, A Musyoki, B Kagina, C Feldman, D Reddy, E du Toit, E Kalanxhi, J Meyer, I Impalli, M Schönfeldt, M Sibanda, N Schellack, P Skosana, S Essack, S Dlamini, Y Ramsamy

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Predicting Axillary Lymph Node Metastasis in Young Onset Breast Cancer: A Clinical-Radiomics Nomogram Based on DCE-MRI by Dong X, Meng J, Xing J, Jia S, Li X, Wu S

“…Xia Dong,1 Jingwen Meng,1 Jun Xing,2 Shuni Jia,3 Xueting Li,4 Shan Wu1 1Department of Radiology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, People’s Republic of China; 2Department of Breast Surgery, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, People’s Republic of China; 3Department of Ultrasound, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, People’s Republic of China; 4Department of Pathology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, People’s Republic of ChinaCorrespondence: Shan Wu, Department of Radiology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, No. 99, Longcheng Street, Taiyuan, Shanxi Province, 030032, People’s Republic of China, Tel +86 03518368398, Email drshanwu@outlook.comBackground: Young onset breast cancer, diagnosed in women under 50, is known for its aggressive nature and challenging prognosis. …”
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NUDT21 regulates lysyl oxidase-like 2(LOXL2) to influence ECM protein cross-linking in silica-induced pulmonary fibrosis by Lan Peng, Wenqing Sun, Demin Cheng, Xinying Jia, Wenxiu Lian, Ziwei Li, Haojie Xiong, Ting Wang, Yi Liu, Chunhui Ni

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The Differential Expressions and Associations of Intracellular and Extracellular GRP78/Bip with Disease Activity and Progression in Rheumatoid Arthritis by Guoyin Liu, Jianping Wu, Yongqiang Wang, Yuansheng Xu, Chun Xu, Guilin Fang, Xin Li, Jianmin Chen

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Accuracy of Pretransplant Imaging Diagnostic for Hepatocellular Carcinoma: A Retrospective German Multicenter Study by Uta Herden, Wenzel Schoening, Johann Pratschke, Steffen Manekeller, Andreas Paul, Richard Linke, Thomas Lorf, Frank Lehner, Felix Braun, Dirk L. Stippel, Robert Sucher, Hartmut Schmidt, Christian P. Strassburg, Markus Guba, Marieke van Rosmalen, Xavier Rogiers, Undine Samuel, Gerhard MSc Schön, Bjoern Nashan

“…According to the German waitlist guidelines, imaging has to be reported to the allocation organization (Eurotransplant) and pathology reports have to be submitted thereafter. …”
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Anatomical and Functional Outcomes of Vitrectomy with/without Intravitreal Methotrexate Infusion for Management of Proliferative Vitreoretinopathy Secondary to Rhegmatogenous Retin... by Samir El Baha, Mahmoud Leila, Ahmed Amr, Mohamed M. A. Lolah

“…Intravitreal infusion has the advantage of blocking the pathology in its nascence and obviates the need for repeated intravitreal injections of the drug.…”
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Roles of the rpoEc-chrR-chrA operon in superoxide tolerance and β-lactam susceptibility of Stenotrophomonas maltophilia by Ren-Hsuan Ku, Hsu-Feng Lu, Li-Hua Li, Li-Hua Li, Ting-Yu Yeh, Yi-Tsung Lin, Yi-Tsung Lin, Tsuey-Ching Yang

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Determining the effect of frailty on survival in advanced ovarian cancer: study protocol for a prospective multicentre national cohort study (FOLERO) by Daniel Hunde, Niklas Ekerstad, Mihaela Asp, Päivi Kannisto, Madelene Wedin, Charlotte Palmqvist, Pernilla Dahm-Kähler, Yvonne Brandberg, Mirna Abraham-Nordling, Kristina Åhlund, Vilhelm Mörlin, Nina Groes-Kofoed, Sahar Salehi

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Risk of SARS-CoV-2 infection before and after the Omicron wave in a cohort of healthcare workers in Ontario, Canada by Jorge L. Martinez-Cajas, Ann Jolly, Yanping Gong, Gerald Evans, Santiago Perez-Patrigeon, Bradley Stoner, T. Hugh Guan, Beatriz Alvarado

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Renewed Global Partnerships and Redesigned Roadmaps for Rabies Prevention and Control by Tiziana Lembo, Michaël Attlan, Hervé Bourhy, Sarah Cleaveland, Peter Costa, Katinka de Balogh, Betty Dodet, Anthony R. Fooks, Elly Hiby, Fernando Leanes, François-Xavier Meslin, Mary Elizabeth Miranda, Thomas Müller, Louis H. Nel, Charles E. Rupprecht, Noël Tordo, Abbigail Tumpey, Alexander Wandeler, Deborah J. Briggs

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Development and validation of a novel artificial intelligence algorithm for precise prediction the postoperative prognosis of esophageal squamous cell carcinoma by Zichen Wang, Zhihan Xiao, Tongyu Zhang, Meiyou Lu, Hai Li, Jing Cao, Jianan Zheng, Yichan Zhou, Juncheng Dai, Cheng Wang, Liang Chen, Jing Xu

“…Methods We conducted LASSO regression analysis of protein-coding CTGs and clinical characteristics from 119 pathologically confirmed ESCC patients to recognize powerful predictive variables. …”
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Utility of Pulse Oximetry Oxygen Saturation (SpO2) with Incorporation of Positive End-Expiratory Pressure (SpO2∗10/FiO2∗PEEP) for Classification and Prognostication of Patients wit... by Pratibha Todur, Anitha Nileshwar, Souvik Chaudhuri, Nitin Gupta, Srikant Natarajan, Shwethapriya Rao

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