The roadmap to integrate diversity, equity, and inclusion in hematology clinical trials: an American Society of Hematology initiative by Alice Kuaban, Alysha K. Croker, Jeffrey Keefer, Leonard A. Valentino, Barbara E. Bierer, Stephen Boateng, Donna DiMichele, Patrick Fogarty, C. Michael Gibson, Anna M. Hood, Lloryn Hubbard, Antonella Isgrò, Karin Knobe, Leslie Lake, Iman Martin, Michel Reid, Jonathan C. Roberts, Wendy Tomlinson, Lanre Tunji-Ajayi, Harriette G.C. Van Spall, Caroline Voltz-Girolt, Allison P. Wheeler, Alan E. Mast, Stephanie Seremetis

Get full text

Kidney and liver histopathology of sea bass Lates calcarifer infected with black body syndrome-associated bacteria by Sri Nuryati, Mauliza Yanti, Rahman, Sutiastuti Wahyuwardani

“…Microscopic anatomical pathology of each bacterium needs to be done to determine its pathogenicity. …”
Get full text

Predictors of biochemical and structural response to medical therapy in patients with active acromegaly following surgery: a real-world perspective by Maryam Rafieemanesh, Manizhe Ataee Kachuee, Ali Zare Mehrjardi, Alireza Khajavi, Mohammad Ghorbani, Mohammad Reza Mohajeri-Tehrani, Nahid Hashemi-Madani, Mohammad E. Khamseh

Get full text

Safety and Potential Complications of Facial Wrinkle Correction with Dermal Fillers: A Systematic Literature Review by Audra Janovskiene, Deividas Chomicius, Dominykas Afanasjevas, Zygimantas Petronis, Dainius Razukevicius, Egle Jagelaviciene

Get full text

The age-adjusted international prognostic index 2 (A-FLIPI2) for elderly patients with follicular lymphoma by Jiesong Wang, Junlei Jia, Jingwei Yu, Jing Liu, Meng Gao, Hengqi Liu, Lanfang Li, Lihua Qiu, Shiyong Zhou, Bin Meng, Wenchen Gong, Zhengzi Qian, Xianhuo Wang, Huilai Zhang

Get full text

Clinical and genetic drivers of oligo-metastatic disease in colon cancer by Alessandro Ottaiano, Mariachiara Santorsola, Roberto Sirica, Annabella Di Mauro, Antonella Di Carlo, Monica Ianniello, Francesco Sabbatino, Rosa Castiello, Francesca Del Peschio, Marco Cascella, Francesco Perri, Maurizio Capuozzo, Nicola Martucci, Edoardo Mercadante, Valentina Borzillo, Rossella Di Franco, Francesco Izzo, Vincenza Granata, Carmine Picone, Antonella Petrillo, Massimiliano Berretta, Salvatore Stilo, Luca Tarotto, Anna Chiara Carratù, Gerardo Ferrara, Madhura Tathode, Alessia Maria Cossu, Marco Bocchetti, Michele Caraglia, Guglielmo Nasti, Giovanni Savarese

Get full text

Occurrence of Fatal and Nonfatal Adverse Outcomes after Heart Transplantation in Patients with Pretransplant Noncytotoxic HLA Antibodies by Luciano Potena, Andrea Bontadini, Sandra Iannelli, Fiorenza Fruet, Ornella Leone, Francesco Barberini, Laura Borgese, Valentina Manfredini, Marco Masetti, Gaia Magnani, Francesco Fallani, Francesco Grigioni, Angelo Branzi

“…Of the subgroup of 37 patients suspected for antibody mediated rejection (AMR), the 9 with pretransplant HLA ab were more likely to display pathological AMR grade 2 (P=0.04). By an inexpensive, luminex-based, HLA-screening assay, we were able to detect non-cytotoxic HLA ab predicting fatal and nonfatal adverse outcomes after heart transplant. …”
Get full text

Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model by Frida Wilske, Olof Eriksson, Rose-Marie Amini, Sergio Estrada, Helena Janols, Amina Khalil, Anders Larsson, Miklós Lipcsey, Sara Mangsbo, Jonathan Sigfridsson, Jan Sjölin, Paul Skorup, Anders Wall, Viola Wilson, Markus Castegren, Gunnar Antoni

Get full text

Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance by Wenjing Xue, Haiqing Liu, Ziheng Su, Siqi Wang, Junping Cheng, Yunzhi Pan, Lurong Zhang

“…The therapeutic effects were evaluated through pathology, biochemical tests, and ELISA. The therapeutic mechanism of QgYp for HF was predicted through network pharmacology. …”
Get full text

A preliminary study on the prognostic significance of cysteine-rich EGF ligand domain 2 protein (CRELD2) in patients with triple negative breast cancer by Mehmet Zahid Kocak, Murat Araz, Siddika Findik, Aykut Demirkiran, Mustafa Korkmaz, Melek Karakurt Eryilmaz, Mehmet Artac

Get full text

Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells by Chu-An Wang, Ya-Chin Hou, Yi-Kai Hong, Yu-Jing Tai, Chieh Shen, Pei-Chi Hou, Jhao-Lin Fu, Cheng-Lin Wu, Siao Muk Cheng, Daw-Yang Hwang, Yung-Yeh Su, Yan-Shen Shan, Shaw-Jenq Tsai

Get full text

Molecular detection of parasites and host preference in wild-caught Culicoides biting midges (Diptera: Ceratopogonidae) in Chiang Mai and Nakhon Si Thammarat Provinces, Thailand by Kyi Soe Baby, Kaewmee Saowalak, Mano Chonlada, Pattanawong Urassaya, Tipparawong Nopporn, Siriyasatien Padet, Gatherer Derek, Urbaniak Michael D., Bates Paul A., Jariyapan Narissara

Get full text

Urinary human papillomavirus DNA as an indicator of gynaecological infection in young women in Schistosoma and HIV endemic South Africa by P. Pillay, H. N. Galappaththi-Arachchige, M. Taylor, B. Roald, B. Roald, E. F. Kjetland, E. F. Kjetland

Get full text

Cancer-associated fibroblasts promote pro-tumor functions of neutrophils in pancreatic cancer via IL-8: potential suppression by pirfenidone by Tomohiko Yagi, Shunsuke Kagawa, Shohei Nogi, Atsuki Taniguchi, Masashi Yoshimoto, Kanto Suemori, Yasuo Nagai, Shuto Fujita, Shinji Kuroda, Satoru Kikuchi, Yoshihiko Kakiuchi, Fuminori Teraishi, Kosei Takagi, Toshiaki Ohara, Hiroshi Tazawa, Toshiyoshi Fujiwara

Get full text

Clinicopathological and Prognostic Significance of CD47 Expression in Lung Neuroendocrine Tumors by Mario Orozco-Morales, Alejandro Avilés-Salas, Norma Hernández-Pedro, Rodrigo Catalán, Graciela Cruz-Rico, Ana Laura Colín-González, Elsa Dosal-Mancilla, Pedro Barrios-Bernal, Oscar Arrieta

“…Then, we analyzed if there was any correlation between CD47 expression with any clinical or pathological characteristic. We also analyzed the prognostic significance of CD47, assessed as progression-free survival and overall survival. …”
Get full text

Patient and tumor factors contributing to distant metastasis in well-differentiated thyroid cancer: a retrospective cohort study by Usman Khan, Ayham Al Afif, Abdullah Aldaihani, Colin MacKay, Matthew H. Rigby, Murali Rajaraman, Syed Ali Imran, Martin J. Bullock, S. Mark Taylor, Jonathan R. B. Trites, Robert D. Hart

“…There is limited information available to clinicians regarding pathological features that confer a higher risk of distant metastasis (DM). …”
Get full text

Case report: Chest radiotherapy-induced vertebral fractures in lung cancer patients: a case series and literature review by Oscar Arrieta, Francisco Lozano-Ruiz, Alberto Guijosa, Pamela Soberanis-Pina, Monika Blake-Cerda, Ana Pamela Gómez-García, Federico Maldonado-Magos, Emilio Conde-Flores, Andrés F. Cardona, Sandra Ileana Pérez Álvarez, Luis Antonio Cabrera-Miranda

Get full text

Enhanced Interleukin 6 Trans-Signaling Modulates Disease Process in Amyotrophic Lateral Sclerosis Mouse Models by Carol Milligan, Dale O. Cowley, William Stewart, Alyson M. Curry, Elizabeth Forbes, Brian Rector, Annette Hastie, Liang Liu, Gregory A. Hawkins

“…<b>Results:</b> The results indicate that in animals with enhanced trans-signaling, symptom onset and pathological processes were accelerated, suggesting a role in disease modification. …”
Get full text

Vitamin D3/VDR alleviates double-stranded RNA virus -induced biliary epithelial cell damage by inhibiting autophagy by Na Liu, Pu Zhao, Ping Cao, JunPeng Hui, YongKang Pan, Jiwen Cheng

Get full text

Renal Dysfunction among Ghanaians Living with Clinically Diagnosed Hypertension in the Asutifi-South District: A Cross-Sectional Descriptive Study at the St. Elizabeth Hospital, Hw... by Sylvester Yao Lokpo, James Osei-Yeboah, William K. B. A. Owiredu, Francis Abeku Ussher, Verner Ndudiri Orish, Felix Gadzeto, Paul Ntiamoah, Felix Botchway, Ivan Muanah, Romeo Asumbasiya Aduko

Get full text