Classifying tumour infiltrating lymphocytes in oral squamous cell carcinoma histopathology using joint learning framework by Barun Barua, Genevieve Chyrmang, Kangkana Bora, Gazi N. Ahmed, Lopamudra Kakoti, Manob Jyoti Saikia

“…This approach reflects pathology practices and increases TILs classification accuracy. …”
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Spontaneous Heterotopic Pregnancy: Dual Case Report and Review of Literature by Annika Chadee, Shadi Rezai, Catherine Kirby, Ekaterina Chadwick, Sri Gottimukkala, Abraham Hamaoui, Vasiliy Stankovich, Theodore Hale, Hamid Gilak, Mohammad Momtaz, Harvey Sasken, Cassandra E. Henderson

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68Ga-NOTA-RM26 PET/CT in the evaluation of glioma: a pilot prospective study by Yilin Li, Rongxi Wang, Jingci Chen, Zhaohui Zhu, Yu Wang, Wenbin Ma

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The Prediction Model of High-Frequency Ultrasound Combined with Artificial Intelligence-Assisted Scoring System Improved the Diagnosis of Sclerosing Adenosis and Early Breast Cance... by Ma B, Wu G, Zhu H, Liu Y, Hu W, Zhao J, Liu Y, Liu Q

“…Bingxin Ma,1 Gang Wu,1 Haohui Zhu,1 Yifei Liu,1 Wenjia Hu,1 Jing Zhao,1 Yinlong Liu,1 Qiuyu Liu2 1Department of Ultrasound, Henan Provincial People’s Hospital, Zhengzhou, 450000, People’s Republic of China; 2Department of Pathology, Henan Provincial People’s Hospital, Zhengzhou, 450000, People’s Republic of ChinaCorrespondence: Gang Wu, Email drwugang325@126.com; Haohui Zhu, Email zhh761126@163.comObjective: The study aimed to apply an artificial intelligence (AI)-assisted scoring system, and improve the diagnostic efficiency of Sclerosing adenosis and early breast cancer.Methods: This study retrospectively collected adenopathy patients (156 cases) and early breast cancer patients (150 cases) in Henan Provincial People’s Hospital from August 2020 to April 2023.Results: The area under the curve of the model constructed by clinical ultrasound features and combined AI features to predict and identify the two in the training group was 0.89 and 0.94, respectively. …”
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Surgical Outcomes and Associated Morbidity of Active and Expectant Management of Second-Trimester Placenta Accreta Spectrum (PAS) by Jessian L. Munoz, Rachel Counts, Amanda E. Lacue, Kayla E. Ireland, Patrick S. Ramsey, Kristyn Brandi

“…<i>Materials and Methods:</i> This study is a retrospective case-control study of patients with a pathology-confirmed diagnosis of PAS managed at a single center over 16 years (2005–2020). …”
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Adult Wilms Tumor With Inferior Vena Cava Thrombus on an Incomplete Duplex Collecting System Ureter Fissus Proximalis Managed at a Tertiary Hospital in Tanzania: A Case Report and... by Amini Mitamo Alexandre, Joseph Martin Lori, Gabriel F. Mtaturu, Victor Patrick Sensa, Sylvia Bedas Nsato, Mariam Athumani Mbezi, Obadia V. Nyongole, Charles A. Mkony

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Sex differences in the relationship between body composition and MASLD progression in a murine model of metabolic syndrome by Laura Manjarrés, Aline Xavier, Leticia González, Camila Garrido, Flavia C. Zacconi, Katherine Rivera, Laura Parra, Alkystis Phinikaridou, Cecilia Besa, Marcelo E. Andia

“…These findings highlight the critical role of sex as a biological variable in MASLD pathology and emphasize the influence of body composition and fat distribution on disease progression. …”
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Spinal cord injury induces transient activation of hepatic stellate cells in rat liver by Inmaculada Fernandez-Canadas, Alejandro Badajoz, Jesús Jimenez-Gonzalez, Martin Wirenfeldt, Beatriz Paniagua-Torija, Clara Bravo-Jimenez, Mar Del Cerro, Angel Arevalo-Martin, Daniel Garcia-Ovejero

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Diospyros kaki and Citrus unshiu Mixture Improves Disorders of Lipid Metabolism in Nonalcoholic Fatty Liver Disease by Mi-Rae Shin, Sung Ho Shin, Seong-Soo Roh

“…Subsequently, body weight changes, liver weight, serum liver function and lipid profiles, and liver pathology were examined, and the relative levels of fatty acid synthesis and β-oxidation gene expression were evaluated by western blot. …”
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Concurrent Viewing of H&E and Multiplex Immunohistochemistry in Clinical Specimens by Larry E. Morrison, Tania M. Larrinaga, Brian D. Kelly, Mark R. Lefever, Rachel C. Beck, Daniel R. Bauer

“…<b>Conclusions:</b> Simultaneous staining and detection, as described here, provides the pathologist a means to evaluate complex multiplexed assays, while seated at the microscope, with the added multispectral imaging capability to support digital pathology and artificial intelligence workflows of the future.…”
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Mechanistic insights into epithelial-mesenchymal transition mediated cisplatin resistance in ovarian cancer by Taha Umair Wani, Hyun-Yi Kim, Geum-Hwa Lee, Young Je Lim, Han-Jung Chae, Ji-Ye Kim, Hyonok Yoon

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Shattering the Amyloid Illusion: The Microbial Enigma of Alzheimer’s Disease Pathogenesis—From Gut Microbiota and Viruses to Brain Biofilms by Anna Onisiforou, Eleftheria G. Charalambous, Panos Zanos

“…Probiotics and prebiotics reduce neuroinflammation and Aβ plaques, while antiviral therapies targeting HSV-1 and vaccines like the shingles vaccine show potential to mitigate AD pathology. Developing effective treatments requires standardized methods to identify and measure microbial infections in AD patients, enabling personalized therapies that address individual microbial contributions to AD pathogenesis. …”
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Down syndrome with cryptorchidism and retroperitoneal mixed germ cell tumour in an adult patient: a case report and literature review by Qiang Wang, Hai-bin Zhou, Li Ao, Yi Jiang, Xiao-Cong Zhou

“…Fluorine-2-fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography/CT examination showed an abnormal increase in the FDG uptake in the parenchymal part of the mass, with a maximum standardised uptake value of approximately 10.5. The pathological diagnosis was retroperitoneal mixed germ cell tumour (yolk sac tumour + seminoma). …”
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Daily activity, mood, and quality of life in colorectal cancer patients with chemotherapy‐induced peripheral neuropathy: A mediation effect analysis by Ling‐Chun Lu, Shiow‐Luan Tsay, Sou‐Yi Chang, Chung‐Ming Chen, Chieh‐Yu Liu

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Procedure Time for Gastric Endoscopic Submucosal Dissection according to Location, considering Both Mucosal Circumferential Incision and Submucosal Dissection by Hironori Konuma, Kenshi Matsumoto, Hiroya Ueyama, Hiroyuki Komori, Yoichi Akazawa, Misuzu Ueyama, Yuta Nakagawa, Takashi Morimoto, Tsutomu Takeda, Kohei Matsumoto, Daisuke Asaoka, Mariko Hojo, Akihito Nagahara, Takashi Yao, Akihisa Miyazaki, Sumio Watanabe

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Biological factors controlling starch digestibility in human digestive system by Cheng Li, Yiming Hu, Songnan Li, Xueer Yi, Shuaibo Shao, Wenwen Yu, Enpeng Li

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Geo-epidemiology of temporal artery biopsy-positive giant cell arteritis in Australia and New Zealand: is there a seasonal influence? by Matthew A Brown, Tony R Merriman, Paul G Sanfilippo, Alex W Hewitt, Catherine L Hill, Elisabeth De Smit, Linda Clarke

“…Demographic details including age, sex and date of TAB were collected from collaborating pathology departments. The season in which GCA was diagnosed was determined and compared with previous reports investigating the association between environmental risk factors and GCA.Results Our study comprises data from 2224 TAB-positive patients with GCA; 2099 of which were from patients in Australia and New Zealand. …”
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Exploring Clec9a in dendritic cell-based tumor immunotherapy for molecular insights and therapeutic potentials by Zubair Hussain, Yueteng Zhang, Lu Qiu, Shanshan Gou, Kangdong Liu

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Receipt of specialized palliative care and health care utilization at the end of life in hematological cancer patients – the Stockholm experience by Lena von Bahr, Peter Strang, Torbjörn Schultz, Per Fürst

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Multifactorial Origin of Exertional Rhabdomyolysis, Recurrent Hematuria, and Episodic Pain in a Service Member with Sickle Cell Trait by Nyamkhishig Sambuughin, Mingqiang Ren, John F. Capacchione, Ognoon Mungunsukh, Kevin Chuang, Iren Horkayne-Szakaly, Francis G. O’Connor, Patricia A. Deuster

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