Left Bundle Branch Block Chest Pain Conundrum by Karthik Seetharam, Ayesha Cheema, Gary Friedman, Roman Pachulski

“…Current STEMI management favors emergent invasive angiography; however, recent data suggests the prevalence of coronary obstructive pathology may be as low as 50%. The application of more specific, less-sensitive Sgarbossa electrocardiographic criteria may reduce angiographic assessment in an otherwise high-risk population unlikely to tolerate further myocardial injury. …”
Get full text

An Atypical Presentation of Sporadic Jejunal Burkitt’s Lymphoma by Pratik Naik, James Wang, Michael J. Brazeau, Domingo Rosario

Get full text

Bilateral Ureteral Stenosis with Hydronephrosis as First Manifestation of Granulomatosis with Polyangiitis (Wegener’s Granulomatosis): A Case Report and Review of the Literature by Joelle Suillot, Jürg Bollmann, Samuel Rotman, Eric Descombes

Get full text

αSynuclein and Mitochondrial Dysfunction: A Pathogenic Partnership in Parkinson’s Disease? by David Protter, Charmaine Lang, Antony A. Cooper

“…Mitochondrial dysfunction is also a common theme in PD patients and this review explores the strong possibility that αSynuclein and mitochondrial dysfunction have an inter-relationship responsible for underlying the disease pathology. Amplifying cycles of mitochondrial dysfunction and αSynuclein toxicity can be envisaged, with either being the disease-initiating factor yet acting together during disease progression. …”
Get full text

Metachronous Liver Metastasis from Alpha-Fetoprotein-Producing Gastric Cancer Successfully Treated with Capecitabine/Oxaliplatin Combination Chemotherapy by Soichi Furukawa, Takashi Kobayashi, Saori Shiono, Shuta Nishinakagawa

Get full text

Hepatic epithelioid hemangioendothelioma with TFE3 rearrangement: a case report and literature review by Ke Meng, Xingrong Yang, Sitong Guo, Juan Tao

“…It may be confusing as its manifestations of multifocal lesions on imaging and epithelial histomorphology in pathology. EHE is easy to be mistaken for a metastatic tumor by radiologists and clinicians. …”
Get full text

Elderly Onset Primary Intestinal Lymphangiectasia—A Rare Case by Li‐Han Goh, Madhavan Manoharan, Khean‐Lee Goh

Get full text

A Hypothesis Concerning a Potential Involvement of Ceramide in Apoptosis and Acantholysis Induced by Pemphigus Autoantibodies by Wendy B. Bollag

“…Our hypothesis is that: (1) the autoantibodies generate pathology through an alteration in ceramide metabolism in targeted keratinocytes, resulting in apoptosis and/or cell death and acantholysis, but only when the cell's ability to metabolize ceramide is exceeded, and (2) apoptosis in response to this altered ceramide metabolism is initiated and/or exacerbated by other agents that increase ceramide levels, such as cytokines, ultraviolet irradiation, and senescence.…”
Get full text

Five-Year Long-Term Followup of a Primary Lymph node Gastrinoma: Is a Pancreaticoduodenectomy Justified? by Bernd Jaenigen, Gian Kayser, Berthold Steinke, Oliver Thomusch

Get full text

Interim Restorative Approach for the Management of Congenitally Missing Permanent Mandibular Incisors: Presentation of Three Cases by Prashanth Prakash, Jayadev M. Hallur, Rachana Narse Gowda

Get full text

Isolated Interrupted Aortic Arch: Unexpected Diagnosis in a 63-Year-Old Male by Hassan Javadzadegan, Jahan Porhomayon, Alireza Sadighi, Mehrdad Yavarikia, Nader Nader

Get full text

New Aspects in the Differential Diagnosis and Therapy of Bladder Pain Syndrome/Interstitial Cystitis by Jochen Neuhaus, Thilo Schwalenberg, Lars-Christian Horn, Henry Alexander, Jens-Uwe Stolzenburg

Get full text

De Novo Fibrillary Glomerulonephritis (FGN) in a Renal Transplant with Chronic Hepatitis C by Edward J. Filippone, Christine Chmielewski, Rakesh Gulati, Eric Newman, John L. Farber

Get full text

Development of Asymmetric Facial Depigmentation in a Patient Treated with Dasatinib with New-Onset Hypovitaminosis D: Case Report and Review of the Literature by Kirsten C. Webb, Magdalena Harasimowicz, Monica Janeczek, Jodi Speiser, James Swan, Rebecca Tung

Get full text

Perivascular Wall Tumor in the Brain of a Dog by Margaret Cohn-Urbach, Annie Chen, Gary Haldorson, Stephanie Thomovsky

Get full text

Multifaceted roles of ninjurin1 in immunity, cell death, and disease by Lili Zhu, Yunfei Xu, Yunfei Xu

“…The absence or inhibition of NINJ1 can delay PMR, thereby mitigating the spread of inflammation resulting from cell lysis and preventing the progression of various cell death-related pathologies, suggesting a conserved regulatory mechanism across these processes. …”
Get full text

Reducing anxiety and enhancing confidence in paediatric patients through visual schedules by Gert C. Koekemoer, Ariné Kuyler, Ensa Johnson, Karen van Zijl, Alta J. Terblanche, Khetsiwe P. Masuku, Juan Bornman

Get full text

A Rare Occurrence of Primary Hepatic Leiomyosarcoma Associated with Epstein Barr Virus Infection in an AIDs Patient by Haritha Chelimilla, Kanthi Badipatla, Ariyo Ihimoyan, Masooma Niazi

Get full text

Reoperation as a Result of Raised Intracranial Pressure Associated with Cyst Formation in Tumor Cavity after Intracranial Tumor Resection: A Report of Two Cases by Jinlu Yu, Wenji Xiong, Limei Qu, Haiyan Huang

Get full text

Mapping transcriptomic profiles of seminal vesiculitis and experimental verification by Chenkui Miao, Shaobo Zhang, Jiajin Wu, Meiling Bao, Zengjun Wang, Bianjiang Liu

Get full text