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621
Cellular Stress Responses: Cell Survival and Cell Death
Published 2010-01-01“…The implications of cellular stress responses to human physiology and diseases are manifold and will be discussed in this review in the context of some major world health issues such as diabetes, Parkinson's disease, myocardial infarction, and cancer.…”
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622
Impulse Control Disorders in Parkinson’s Disease: Crossroads between Neurology, Psychiatry and Neuroscience
Published 2013-01-01“…Such behaviours are characterized by an inappropriate drive to conduct repetitive behaviours that are usually socially inadequate or result in harmful consequences. Parkinson disease impulse control disorders (PD-ICDs) have raised significant interest in the scientific and medical community, not only because of their incapacitating nature, but also because they may represent a valid model of ICDs beyond PD and a means to study the physiology of drive, impulse control and compulsive actions in the normal brain. …”
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623
Cross-Talk between Apolipoprotein E and Cytokines
Published 2011-01-01“…Despite its importance in lipid transport and atherosclerosis pathogenesis, apoE is associated with neurodegenerative disorders such as Alzheimer's disease (AD) and Parkinson disease, and autoimmune disorders such as multiple sclerosis and psoriasis. …”
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624
Cellular Programming and Reprogramming: Sculpting Cell Fate for the Production of Dopamine Neurons for Cell Therapy
Published 2012-01-01“…Importantly, the success of clinical applications depends on our ability to steer pluripotent stem cells towards the right neuronal identity. In Parkinson disease, the loss of dopamine neurons is more pronounced in the ventrolateral population that projects to the sensorimotor striatum. …”
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625
EVALUATION OF THE THERAPEUTIC EFFECTS OF SALVIA ROSMARINUS ESSENTIAL OIL ON NERVOUS SYSTEM DISORDERS
Published 2025-02-01“…This review explores the therapeutic potential of rosemary in alleviating nervous system disorders such as Alzheimer's disease (AD), major depressive disorder (MDD), epilepsy, Parkinson's disease (PD), addiction, and attention-deficit hyperactivity disorder (ADHD). …”
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626
Kinetic Modeling of the Mitochondrial Energy Metabolism of Neuronal Cells: The Impact of Reduced α-Ketoglutarate Dehydrogenase Activities on ATP Production and Generation of Reacti...
Published 2012-01-01“…Reduced activity of brain α-ketoglutarate dehydrogenase complex (KGDHC) occurs in a number of neurodegenerative diseases like Parkinson's disease and Alzheimer's disease. In order to quantify the relation between diminished KGDHC activity and the mitochondrial ATP generation, redox state, transmembrane potential, and generation of reactive oxygen species (ROS) by the respiratory chain (RC), we developed a detailed kinetic model. …”
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627
Therapeutic Use of Botulinum Toxin in Neurorehabilitation
Published 2012-01-01“…The use of BTX for the rehabilitation of children with obstetrical brachial plexus palsy and in treating sialorrhea which can complicate the course of some severe neurological diseases such as amyotrophic lateral sclerosis and Parkinson's disease is also addressed. …”
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628
Taltirelin induces TH expression by regulating TRHR and RARα in medium spiny neurons
Published 2024-12-01“…Abstract Taltirelin, an orally effective thyrotropin-releasing hormone analog, significantly improves motor impairments in rat models of Parkinson's disease (PD) and enhances dopamine release within the striatum. …”
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629
Examining vaccination-related adverse events in frequent neurodegenerative diseases
Published 2025-02-01“…This study investigates adverse events following vaccination in patients with four neurodegenerative diseases: Amyotrophic Lateral Sclerosis (ALS), Alzheimer's disease, Multiple Sclerosis (MS), and Parkinson's disease. We applied advanced data processing techniques to analyze symptom patterns and severity scores across these disease groups. …”
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630
Electroconvulsive shock and transcranial magnetic stimulation do not alter the survival or spine density of adult-born striatal neurons.
Published 2025-01-01“…Since striatal dysfunction occurs in Parkinson's disease, which is amenable to neurostimulation therapies, we investigated whether electroconvulsive shock (ECS) or transcranial magnetic stimulation (rTMS) modulate neuroplasticity of adult-born striatal neurons. …”
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631
SPECT Findings in Alzheimer’s Disease and Parkinson’s Disease with Dementia
Published 1997-01-01“…We examined, with single photon emission tomography (SPECT) and (99mTc)-HMPAO, 18 patients with idiopathic Parkinson's disease and no dementia (PD), 12 patients with PD and dementia, 24 patients with probable Alzheimer's disease (AD), and 14 controls. …”
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632
Effect of Grovth Medium on L-Dopa and Dopamine Production Using Citrobacter freundii (NRRL B-2643)
Published 2022-12-01“…In this study, microbial production of L-Dopa and Dopamine which is an important substrance for the treatment of Parkinson's disease were investigated by using Citrobacter freundii (NRRL B-2643). …”
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633
Multiple-System Atrophy with Cerebellar Predominance Presenting as Respiratory Insufficiency and Vocal Cords Paralysis
Published 2010-01-01“…It is considered a rare disease, but many patients are misdiagnosed as suffering from idiopathic Parkinson's disease. In this paper, we report a case of a patient admitted with respiratory failure and vocal cords paralysis due to MSA-c. …”
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634
The Pivotal Role of TBK1 in Inflammatory Responses Mediated by Macrophages
Published 2012-01-01“…Inflammation is considered to be a major cause of most chronic diseases, especially in more than 100 types of inflammatory diseases which include Alzheimer's disease, rheumatoid arthritis, asthma, atherosclerosis, Crohn's disease, colitis, dermatitis, hepatitis, and Parkinson's disease. Recently, an increasing number of studies have focused on inflammatory diseases. …”
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635
Promising Neuroprotective Effects of Dracocephalum Species: Mechanistic Perspectives
Published 2024-12-01“…The role of the genus Dracocephalum was investigated in relation to various neurological conditions such as Alzheimer's disease, insomnia, Parkinson's disease, vascular dementia, cerebral ischemia, pain, depression, and glioblastoma. …”
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636
Don't die like me: Which proteins are responsible for the selective neuronal vulnerability within the substantia nigra?
Published 2024-01-01“…A hallmark of Parkinson's disease is the specific degeneration of dopaminergic neurons in the substantia nigra pars compacta. …”
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637
Investigation of the Possible Correlation between Idiopathic Parkinson’s Disease and Diabetes Mellitus in Egyptian Patients: A Pilot Study
Published 2021-01-01“…To study the diabetes-Parkinson's disease (PD) linkage. Methods. The investigators recorded the rapid eye movement sleep behavior disorder screening questionnaire (RBDSQ) score for 60 diabetic patients: 30 patients were treated with metformin-inclusive sulfonylurea and 30 patients were treated with sulphonylurea(s) monotherapy and matched with 30 controls. …”
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638
Historical Pathways for Opioid Addiction, Withdrawal with Traditional and Alternative Treatment Options with Ketamine, Cannabinoids, and Noribogaine: A Narrative Review
Published 2022-10-01“…These include, but are not limited to epilepsy, Parkinson's disease, multiple sclerosis, chronic pain conditions, anxiety disorders, and addiction. …”
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639
Partnership and Depression in Parkinson’s Disease
Published 1992-01-01“…In this study, the influence of partnership on depression and coping with Parkinson's disease has been investigated. Twenty-three single female patients, 46 married patients (23 female, 23 male) with unimpaired partnership and 42 patients (21 female, 21 male) whose partnership had worsened since the onset of disease, were compared with regard to depression and self reported extent of psychosocial distress. …”
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640
Research on Role of Connexin 36 in Pathogenesis of Rats with Levodopa-induced Dyskinesia
Published 2016-08-01“…Objective:To study the role of striatal connexin 36 (Cx36) in the pathogenesis of levodopa-induced dyskinesia (LID).Methods:A total of 60 SD rats were divided into the normal group, the sham operation group, the Parkinson's disease (PD) group, the experimental group and the control group by a random number table, and 12 rats in each group. …”
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