Oncogene mutations in non-small cell lung cancer patients in Iran: a study of their association with programmed death ligand-1 expression by Zahra Abrehdari-Tafreshi, Majid Pirestani, Zahra Mosaferi, Nasser Rakhshani, Ehsan Arefian

“…Therefore, the identification of mutations in crucial cancer-related genes is paramount for guiding optimal chemotherapy strategies. …”
Get full text

Using dynamic Bayesian belief networks to infer the effects of climate change and human activities on changes in regional ecosystem services by Haoran Yu, Junyi Jiang, Xinchen Gu, Chunwu Cao, Cheng Shen

“…This underscores the paramount importance of forecasting and managing these services for regional sustainability. …”
Get full text

Cultivating clean skies: unveiling the tapestry of air quality in Gujarat through innovative machine learning analysis by Gaddam Advitha, Allada Nagasai Varaprasad, Koti Vennela Khushi, Pullabhotla Vijay, Sukanta Nayak

“…The imperative to accurately forecast Air Quality Indices (AQIs) becomes paramount for the prompt implementation of mitigation measures, thereby safeguarding public well-being. …”
Get full text

Association between Shock Index and Emergency Department Cardiac Arrest by Chao-Tung Chen, Pei-Ming Wang, Chao-Hsin Wu, Chih-Wei Wei, Tai-Lin Huang

“…In the emergency department (ED), early identification of patients at risk of cardiac arrest is paramount, especially in the context of overcrowding. …”
Get full text

Non-pharmacological interventions for the prevention of type 2 diabetes in low-income and middle-income countries: a systematic review of randomised controlled trials by K M Saif-Ur-Rahman, Md Shariful Islam, Anupam Sarker, Rina Das, Saraban Ether

“…All the studies demonstrated a low ROB in most of the bias assessment domains with some unclear results in allocation concealments.Conclusions Emphasising non-pharmacological interventions for T2DM prevention can improve health outcomes and lessen the economic burdens, which will be of paramount importance in LMICs.Systematic review registration number CRD42020191507…”
Get full text

Ventilator-Associated Pneumonia After Cardiac Arrest and Prevention Strategies: A Narrative Review by Harinivaas Shanmugavel Geetha, Yi Xiang Teo, Sharmitha Ravichandran, Amos Lal

“…Given the already elevated mortality rates in cardiac arrest cases, the addition of VAP further diminishes the chances of survival. Consequently, a paramount focus on VAP prevention becomes imperative. …”
Get full text

Integration of Multi-Source Landslide Disaster Data Based on Flink Framework and APSO Load Balancing Task Scheduling by Zongmin Wang, Huangtaojun Liang, Haibo Yang, Mengyu Li, Yingchun Cai

“…To bolster the data support capabilities for the monitoring, prevention, and management of landslide disasters, the efficient integration of multi-source heterogeneous data is of paramount importance. The present study proposes an innovative approach to integrate multi-source landslide disaster data by combining the Flink-oriented framework with load balancing task scheduling based on an improved particle swarm optimization (APSO) algorithm. …”
Get full text

Influence of Cosmetic Skincare Products with pH < 5 on the Skin Microbiome: A Randomized Clinical Evaluation by Ciska Janssens-Böcker, Claudia Doberenz, Marta Monteiro, Marta de Oliveira Ferreira

“…The importance of pH for the microbiome is paramount. Cosmetic skincare products interact with the skin microbiome and skin pH, playing a key role in maintaining microbial balance. …”
Get full text

EVALUATION OF SMARTNESS OF THE TOURISM DESTINATION WEBSITES OF THE KLAIPEDA REGION by Julius Ramanauskas, Šarūnas Banevičius, Putinas Bielskis

“…The concept of a smart city is not merely concerned with operational efficiency; it also seeks to enhance the overall value and quality of life for residents. This is of paramount importance for the sustainable development of urban areas. …”
Get full text

Clinical presentations and outcomes of celiac disease in children and adolescents at a tertiary care center in Lebanon by Dana Andari, Rima Hanna-Wakim, Sarah Khafaja, Nadine Yazbeck

“…The recognition of early manifestations, early diagnosis and strict adherence to the diet are of paramount importance to prevent long term complications.…”
Get full text

Analysis of the Internal Radial Gradient of Chemical Abundances in Spiral Galaxies from CALIFA by A. F. S. Cardoso, O. Cavichia, M. Mollá, L. Sánchez-Menguiano

“…The study of chemical evolution is of paramount importance for understanding the evolution of galaxies. …”
Get full text

Impact of a multiple oversampling technique-based assessment framework on shallow rockburst prediction models by Guozhu Rao, Guozhu Rao, Yunzhang Rao, Yunzhang Rao, Yangjun Xie, Qiang Huang, Jiazheng Wan, Jiyong Zhang

“…The occurrence of class-imbalanced datasets is a frequent observation in natural science research, emphasizing the paramount importance of effectively harnessing them to construct highly accurate models for rockburst prediction. …”
Get full text

Developing a Shariah-compliant medical services framework in Malaysia: an expert system approach using fuzzy Delphi method and interpretive structural modelling by Farrah Ilyani Che Jamaludin, Muhammad Ridhuan Tony Lim Abdullah, Mohd Nuri Al Amin Endut, Shaikh Mohd Saifuddeen, Kamarul Afendey Hamimi, Shariff Harun

“…Introduction In an increasingly diverse healthcare landscape, addressing the specific needs of Muslim patients has become paramount. The absence of comprehensive frameworks for Shariah-compliant healthcare services often poses challenges for healthcare professionals striving to provide care that aligns with Islamic values.Objective The objective of this study was to develop a comprehensive framework for Shariah-compliant healthcare services, ensuring alignment with Islamic practices in healthcare.Methods, setting, participants This consensus study employed a key input approach using the fuzzy Delphi method (FDM) and interpretive structural modelling. …”
Get full text

Multiscale attention network via topology learning for cerebral vessel segmentation in angiography images by Tao Han, Junchen Xiong, Tingyi Lin, Tao An, Cheng Wang, Jianjun Zhu, Zhongliang Li, Ligong Lu, Yi Zhang, Gao-Jun Teng

“…The accurate extraction of cerebral vessel structures is of paramount importance in the diagnosis and treatment of cerebrovascular diseases. …”
Get full text

Integrated transmission expansion planning incorporating fault current limiting devices and thyristor-controlled series compensation using meta-heuristic optimization techniques by Abdulaziz Almalaq, Khalid Alqunun, Rabeh Abbassi, Ziad M. Ali, Mohamed M. Refaat, Shady H. E. Abdel Aleem

“…In TEP, prioritizing solution quality is paramount over algorithm speed.…”
Get full text

Emerging trends in nano-sensors: A new frontier in food safety and quality assurance by Farhang Hameed Awlqadr, Ammar B. Altemimi, Syamand Ahmed Qadir, Tablo Azad Hama Salih, Zina T. Alkanan, Qausar Hamed AlKaisy, Othman Abdulrahman Mohammed, Mohammad Ali Hesarinejad

“…The rapid evolution of nanotechnology has catalyzed significant advancements in the design and application of nano-sensors, particularly within the food industry, where ensuring safety and quality is of paramount concern. This review explores the multifaceted role of nano-sensors constructed from diverse nanomaterials in detecting foodborne pathogens and toxins, offering a comprehensive analysis of their operational principles, sensitivity, and specificity. …”
Get full text

Identification of new reference genes with stable expression patterns for cell cycle experiments in human leukemia cell lines by Otília Tóth, Gergely Attila Rácz, Eszter Oláh, Máté Tóth, Edit Szabó, György Várady, Beáta G. Vértessy, Nikolett Nagy

“…For cancer cells, analysis of cell cycle-related events is of paramount significance since tumorigenesis is characteristically coupled to cell cycle perturbations. …”
Get full text

Ascaris lumbricoides a rare cause gastric perforation: a case report and brief literature review by Tian-Hao Xie, Tian-Hao Xie, Yan Fu, Xiang-Xiang Ren, Xin-Li Sun, Qiang Wang, Qian Sun

“…This case highlights the crucial importance of recognizing ascariasis-associated complications and underscores the paramount role of timely surgical intervention in such cases. …”
Get full text

Atomically engineering interlayer symmetry operations of two-dimensional crystals by Ziyi Han, Shengqiang Wu, Chun Huang, Fengyuan Xuan, Xiaocang Han, Yinfeng Long, Qing Zhang, Junxian Li, Yuan Meng, Lin Wang, Jiahuan Zhou, Wenping Hu, Jingsi Qiao, Dechao Geng, Xiaoxu Zhao

“…Abstract Crystal symmetry, which governs the local atomic coordination and bonding environment, is one of the paramount constituents that intrinsically dictate materials’ functionalities. …”
Get full text

Comparing the Fiscal Consequences of Controlled and Uncontrolled Osteoarthritis Pain Applying a UK Public Economic Perspective by Rui Martins, Nikos Kotsopoulos, Melodi Kosaner Kließ, Craig Beck, Lucy Abraham, Samuel Large, Patricia Schepman, Mark P. Connolly

“…**Conclusions:** For governments, maintaining an active workforce is paramount to maintaining economic growth and reducing spending on government programs. …”
Get full text