Potential of emodepside for vector-borne disease control by Pattarapon Khemrattrakool, Thitipong Hongsuwong, Theerawit Phanphoowong, Patchara Sriwichai, Kittiyod Poovorawan, Joel Tarning, Kevin C. Kobylinski

“…Emodepside targets the calcium-activated voltage-gated potassium slowpoke 1 (SLO-1) channels of presynaptic nerves of pharynx and body wall muscle cells of nematodes leading to paralysis, reduced locomotion and egg laying, starvation, and death. …”
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A Case of Nasopharyngeal Mycobacteriosis with Bony Erosion of the External Skull Base by Kohei Matsuo, Satoshi Tanaka, Masayuki Sakata, Hiroki Takeda, Akihiro Nagata, Masashi Mori, Rie Ito, Yoshifumi Yamamoto, Kiyonobu Ueno, Atsuhiko Uno

“…However, this was followed by glossopharyngeal and vagus nerve paralysis. Computed tomography (CT) showed a diffuse enhancing mucosal irregularity in the nasopharynx with bony erosion of the external skull base. …”
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NMO-IgG and AQP4 Peptide Can Induce Aggravation of EAMG and Immune-Mediated Muscle Weakness by Tehila Mizrachi, Livnat Brill, Malcolm Rabie, Yoram Nevo, Yakov Fellig, Mayan Zur, Dimitrios Karussis, Oded Abramsky, Talma Brenner, Adi Vaknin-Dembinsky

“…Injection of either AQP4 peptide or NMO-Ig to EAMG or to naive mice caused increased fatigability and aggravation of EAMG symptoms as expressed by augmented muscle weakness (but not paralysis), decremental response to repetitive nerve stimulation, increased neuromuscular jitter, and aberration of immune responses. …”
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Stem Cell Therapy for the Treatment of Amyotrophic Lateral Sclerosis: Comparison of the Efficacy of Mesenchymal Stem Cells, Neural Stem Cells, and Induced Pluripotent Stem Cells by Lauren Frawley, Noam Tomer Taylor, Olivia Sivills, Ella McPhillamy, Timothy Duy To, Yibo Wu, Beek Yoke Chin, Chiew Yen Wong

“…With an incidence rate of about 4.42 cases per 100,000 people annually, ALS severely impacts motor function and quality of life, causing progressive muscle atrophy, spasticity, paralysis, and eventually death. The cause of ALS is largely unknown, with 90% of cases being sporadic and 10% familial. …”
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Clinical Efficacy of Platelet-Rich Plasma in the Treatment of Neurotrophic Corneal Ulcer by Dominika Wróbel-Dudzińska, Jorge Alio, Alejandra Rodriguez, Ewa Suchodoła-Ratajewicz, Ewa Kosior-Jarecka, Beata Rymgayłło-Jankowska, Agnieszka Ćwiklińska-Haszcz, Tomasz Żarnowski

“…The study group consists of 25 patients with nonhealing corneal ulcers due to herpes simplex or herpes zoster infection and facial nerve or trigeminal nerve paralysis as a result of a neurosurgical operation caused by a tumour or stroke. …”
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Identification and Quality Evaluation of Raw and Processed Asarum Species Using Microscopy, DNA Barcoding, and Gas Chromatography-Mass Spectrometry by Guangzhe Yao, Wenjuan Ma, Xuhua Huang, Qi Jia, Jiayuan Shen, Yanxu Chang, Huizi Ouyang, Jun He

“…Some volatile components of Asarum which have toxic effect may cause adverse reactions such as headache, general tension, unconsciousness, and respiratory paralysis. Therefore, Asarum is normally processed to reduce such toxicity and adverse effects. …”
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Human Motor Neuron Progenitor Transplantation Leads to Endogenous Neuronal Sparing in 3 Models of Motor Neuron Loss by Tanya J. Wyatt, Sharyn L. Rossi, Monica M. Siegenthaler, Jennifer Frame, Rockelle Robles, Gabriel Nistor, Hans S. Keirstead

“…Motor neuron loss is characteristic of many neurodegenerative disorders and results in rapid loss of muscle control, paralysis, and eventual death in severe cases. In order to investigate the neurotrophic effects of a motor neuron lineage graft, we transplanted human embryonic stem cell-derived motor neuron progenitors (hMNPs) and examined their histopathological effect in three animal models of motor neuron loss. …”
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The <i>Meq</i> Genes of Nigerian Marek’s Disease Virus (MDV) Field Isolates Contain Mutations Common to Both European and US High Virulence Strains by Joseph N. Patria, Luka Jwander, Ifeoma Mbachu, Levi Parcells, Brian Ladman, Jakob Trimpert, Benedikt B. Kaufer, Phaedra Tavlarides-Hontz, Mark S. Parcells

“…MD is characterized by paralysis, immune suppression, and the rapid formation of T-cell (primarily CD4+) lymphomas. …”
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Reconstructive trends and complications following parotidectomy: incidence and predictors in 11,057 cases by Cory Donovan Bovenzi, Peter Ciolek, Meghan Crippen, Joseph M. Curry, Howard Krein, Ryan Heffelfinger

“…Reconstruction following parotidectomy is utilized to address contour deformity and facial nerve paralysis. This study aims to demonstrate national trends in parotidectomy patients and identify factors associated with adverse postoperative outcomes. …”
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Locked-in Syndrome: Insights into Etiology, Diagnosis, Management, and Quality of Life by Urszula Zelik, Wojciech Florczak, Joanna Śnieżna, Jakub Dziewic, Karol Dzwonnik, Wiktoria Domino, Gabriela Trestka, Maria Przygoda, Jagienka Włodyka, Kamila Stępień, Sabina Adamczyk

“… Locked-in Syndrome (LIS) is a rare and severe neurological condition resulting from damage to the ventral pons, leading to complete paralysis of voluntary muscles while preserving consciousness and cognitive function. …”
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Gross recurrent laryngeal nerve invasion by extranodal extension in thyroid carcinoma by Xin Li, Xiang-yun Yao, Shi-rong Liu, Fang Mei, Bo Yu, Bing-yan Wang, Shi-bing Song, Shi Tan

“…Permanent vocal cord paralysis occurred in two (13.3%) cases receiving neurectomy, of which one was of the PTC group, and the other one belonged to the MTC group. …”
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Delayed facial nerve decompression for severe refractory cases of Bell’s palsy: a 25-year experience by Ilyes Berania, Mohamed Awad, Issam Saliba, Jean-Jacques Dufour, Marc-Elie Nader

“…Conclusions When indicated, facial nerve decompression for BP is usually recommended within the first 2 weeks of onset of facial paralysis. Nonetheless, our results suggest that patients with severe BP could benefit from decompression surgery within 90 days after onset of symptoms in the absence of an opportunity to proceed earlier to surgery. …”
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Electroacupuncture Involved in Motor Cortex and Hypoglossal Neural Control to Improve Voluntary Swallowing of Poststroke Dysphagia Mice by Shuai Cui, Shuqi Yao, Chunxiao Wu, Lulu Yao, Peidong Huang, Yongjun Chen, Chunzhi Tang, Nenggui Xu

“…Four main conclusions can be drawn from our study: (i) EA may enhance the local field potential in noninfarction area of M1, activate the swallowing-related neurons (pyramidal cells), and increase the motor conduction of noninfarction area in voluntary swallowing; (ii) EA may improve the blood flow in both M1 on the healthy side and deglutition muscles and relieve PSD symptoms; (iii) EA could increase the motor conduction velocity (MCV) in hypoglossal nerve, enhance the EMG of mylohyoid muscle, alleviate the paralysis of swallowing muscles, release the substance P, and restore the ability to drink water; and (iv) EA can boost the functional compensation of M1 in the noninfarction side, strengthen the excitatory of hypoglossal nerve, and be involved in the voluntary swallowing neural control to improve PSD. …”
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Bp-13 PLA2: Purification and Neuromuscular Activity of a New Asp49 Toxin Isolated from Bothrops pauloensis Snake Venom by Georgina Sucasaca-Monzón, Priscila Randazzo-Moura, Thalita Rocha, Frank Denis Torres-Huaco, Augusto Vilca-Quispe, Luis Alberto Ponce-Soto, Sérgio Marangoni, Maria Alice da Cruz-Höfling, Léa Rodrigues-Simioni

“…In the mouse phrenic nerve-diaphragm (PND) preparation, the time for 50% paralysis was concentration-dependent (P<0.05). Both the replacement of Ca2+ by Sr2+ and temperature lowering (24°C) inhibited the Bp-13 PLA2-induced twitch-tension blockade. …”
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Predictors of the Short‐Term Outcomes of Guillain–Barré Syndrome: Exploring Electrodiagnostic and Clinical Features by Yi‐Hsiang Chen, Chia‐Lun Wu, Wei‐Chieh Weng, Yi‐Chia Wei

“…ABSTRACT Background and Objectives Guillain–Barré syndrome (GBS), an acute inflammatory disorder of the peripheral nervous system, is characterized by muscle weakness and paralysis. Prompt identification of patients at a high risk of poor outcomes is crucial for timely intervention. …”
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An Investigation of Manifold-Based Direct Control for a Brain-to-Body Neural Bypass by E. Losanno, M. Badi, E. Roussinova, A. Bogaard, M. Delacombaz, S. Shokur, S. Micera

“…<italic>Objective:</italic> Brain-body interfaces (BBIs) have emerged as a very promising solution for restoring voluntary hand control in people with upper-limb paralysis. The BBI module decoding motor commands from brain signals should provide the user with intuitive, accurate, and stable control. …”
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NLRX1 limits inflammatory neurodegeneration in the anterior visual pathway by Alexander J. Gill, Matthew D. Smith, Danny Galleguillos, Thomas Garton, Jackson W. Mace, Sachin P. Gadani, Swati Kumar, Aayush Pokharel, Krista Solem, Saahith Potluri, Omar Hussein, Giuliana Sardi Rogines, Arihant Singh, Annatje Clark, Peter A. Calabresi, Marjan Gharagozloo

“…Moreover, treating EAE mice with oral LABP-66, compared to vehicle, after the onset of paralysis resulted in less anterior visual pathway neurodegeneration. …”
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Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS) by Robert Chen, Angus G K McNair, Vafa Rahimi-Movaghar, Julio C Furlan, Benjamin M Davies, Oliver D Mowforth, Iwan Sadler, Bizhan Aarabi, Brian K Kwon, Michael G Fehlings, James S Harrop, Armin Curt, Ellen Sarewitz, Carl Moritz Zipser, Timothy F Boerger, Mark R N Kotter, James Milligan, Lindsay Tetreault, Danyal Khan, Keng Siang Lee, Alvaro Yanez Touzet, Ricardo Rodrigues-Pinto, James D Guest, Sukhvinder Kalsi-Ryan, Shirley Widdop

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Retrospective Study of Chronic Coughing in Dogs in a Referral Centre in the UK: 329 Cases (2012–2021) by Carla Asorey Blazquez, Ico Jolly Frahija, Arran Smith, Rachel Miller, Mayank Seth, Edgar Garcia Manzanilla, Ferran Valls Sanchez

“…Higher body weight (OR 1.105, 95%, CI: 1.061–1.150), older age (OR 1.041, 95%, CI: 1.022–1.061), and regurgitation were predictive factors of laryngeal paralysis. Epiglottic retroversion was associated with younger age (OR 0.969, 95%, CI: 0.943–0.994), dysphagia (OR 42.5, 95%, CI: 4.7–382.7), and regurgitation (OR 11.6, 95%, CI: 1.2–113.1). …”
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Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice by Ali Yousefian-Jazi, Suhyun Kim, Jiyeon Chu, Seung-Hye Choi, Phuong Thi Thanh Nguyen, Uiyeol Park, Min-gyeong Kim, Hongik Hwang, Kyungeun Lee, Yeyun Kim, Seung Jae Hyeon, Hyewhon Rhim, Hannah L. Ryu, Grewo Lim, Thor D. Stein, Kayeong Lim, Hoon Ryu, Junghee Lee

“…Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the loss of both upper and lower motor neurons, leading to progressive paralysis. Both genetic alterations and epigenetic modifications contribute to neuronal dysfunction in the pathogenesis of ALS. …”
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